Hüseyin Kaya

Sparsely populated folding intermediates of the Fyn SH3 domain: Matching native-centric essential dynamics and experiment

Ollerenshaw, Jason E., Kaya, Hüseyin, Chan, Hue Sun, Kay, Lewis E.

A complete description of how a protein folds requires the characterization of intermediate conformations traversed during the folding transition. We have calculated dynamics trajectories of a...

Chevron Behavior and Isostable Enthalpic Barriers in Protein Folding: Successes and Limitations of Simple Gō-like Modeling

Kaya, Hüseyin, Liu, Zhirong, Chan, Hue Sun

It has been demonstrated that a “near-Levinthal” cooperative mechanism, whereby the common Gō interaction scheme is augmented by an extra favorability for the native state as a whole, can lead...

Sparsely populated folding intermediates of the Fyn SH3 domain: Matching native-centric essential dynamics and experiment

Ollerenshaw, Jason E., Kaya, Hüseyin, Chan, Hue Sun, Kay, Lewis E.

A complete description of how a protein folds requires the characterization of intermediate conformations traversed during the folding transition. We have calculated dynamics trajectories of a...

Chevron Behavior and Isostable Enthalpic Barriers in Protein Folding: Successes and Limitations of Simple Gō-like Modeling

Kaya, Hüseyin, Liu, Zhirong, Chan, Hue Sun

It has been demonstrated that a “near-Levinthal” cooperative mechanism, whereby the common Gō interaction scheme is augmented by an extra favorability for the native state as a whole, can lead...