H. Eisen

Publication List Details

Period

1977 - 2004

Number

68

Co-Authors

Overview of the Mars Reconnaissance Orbiter mission (2004)

Mateer, B., Graf, J., Zurek, R., Jones, R., Eisen, H., Johnston, M., ...

The Mars Reconnaissance Orbiter will deliver to Mars orbit a payload to conduct remote sensing science observations, characterize sites for future landers, and provide critical telecom/navigation...

Sojourner Mars Rover Thermal Performance (2004)

Eisen, H., Wen, L. C., Hickey, G., Braun, D. F.

This paper summarizes the Rover's design and performance as well as post-mission model correlation.

Soil-Like Deposits Observed by Sojourner, The Pathfinder Rover (2004)

Bickler, D., Moore, H., Crisp, J., Eisen, H., Gensler, J., Haldemann, A., ...

Most of the soil-like materials at the Pathfinder landing site behave like moderately dense soils on Earth with friction angles near 34 degrees through 39 degrees and are called cloddy deposits.

Second generation Mars landed missions (2004)

Graf, J., Rivellini, T., Sabahi, D., Thurman, S., Eisen, H.

This paper addresses some of the candidate missions being considered for the next generation projects, discusses the new approaches being developed to implement safe and accurate entry, descent and...

SRTM on-orbit structural dynamics (2004)

Umland, J. W., Eisen, H.

One of SRTM's significant features is the use of a 60 meter long deployable mast that serves to deploy an outboard antenna and creates a stable baseline.

La Dirección Ante el Diagnóstico Empresarial (1977)

Boyce, R.O., Eisen, H.

Traducción de: Management Diagnosis: A Practical Guide

The major 85-kDa surface antigen of the mammalian-stage forms of Trypanosoma cruzi is a family of sialidases.

Kahn, S, Colbert, T G, Wallace, J C, Hoagland, N A, Eisen, H

Trypanosoma cruzi, an intracellular protozoan parasite infecting a wide variety of vertebrates, is the agent responsible for Chagas disease in humans. An estimated 15-20 million people in South and...

Growth properties of Cellulomonas flavigena mutants affected in cellulose utilization.

Béguin, P, Eisen, H

The role of cellobiose metabolism in cellulose utilization by Cellulomonas flavigena was investigated by studying mutants unable to grow on cellobiose or cellulose. The results show that the ability...

In vitro activation of bacteriophage P2 late gene expression by extracts from phage P4-infected cells.

Gibbs, W, Eisen, H, Calendar, R

We have used a cell-free, DNA-dependent protein-synthesizing system to study the stimulation of phage P2 late gene expression by satellite phage P4. An activity is present in extracts prepared from...

Regulation of Repressor Expression in λ*

Eisen, H., Brachet, P., Silva, L. Pereira Da, Jacob, F.

A new gene in bacteriophage λ is described. The product of this gene cro prevents expression of immunity and regulates the expression of those genes to the left of the immunity region. cro- mutants...

Myeloproliferative virus, a cloned murine sarcoma virus with spleen focus-forming properties in adult mice.

Ostertag, W, Vehmeyer, K, Fagg, B, Pragnell, I B, Paetz, W, Le Bousse, M C, ...

Myeloproliferative virus, derived from Moloney sarcoma virus, causes erythroleukemia and myeloid leukemia in adult mice. This virus is also capable of fibroblast transformation in vitro. The virus...

Active late-appearing variable surface antigen genes in Trypanosoma equiperdum are constructed entirely from pseudogenes.

Roth, C, Bringaud, F, Layden, R E, Baltz, T, Eisen, H

The expression of genes coding for variable surface glycoproteins (VSGs) in Trypanosoma equiperdum is linked to duplicative transpositions of silent, basic copy sequences into telomere-linked...

Organization of four mouse lambda light chain immunoglobulin genes.

Blomberg, B, Traunecker, A, Eisen, H, Tonegawa, S

We have cloned four lambda light chain constant region (C) genes from mouse embryo DNA. Each carries its own joining (J) segment approximately 1.3 kilobases to its 5' side. The four C genes occur in...

Deletions of lambda phage locating a prm mutation within the rightward operator.

Smith, G R, Eisen, H, Reichardt, L, Hedgepeth, J

Two deletion-substitution mutations of phage lambda, spi-113 and spi-274, are shown to remove about half of the rightward operator OR. Physiological studies show that spi-113 is still repressible....

Developmental and hormonal regulation of protein H1 degrees in rodents.

Gjerset, R, Gorka, C, Hasthorpe, S, Lawrence, J J, Eisen, H

The tissue and cellular distribution and regulation of the chromatin protein H1 degrees has been examined in developing and adult mouse and in rat. The protein appears in specific cell types of solid...

Novel bacteriophage lambda mutation affecting lambda head assembly.

Georgopoulos, C P, Bisig, R, Magazin, M, Eisen, H, Court, D

A novel phage lambda mutation, called dc10, which interferes with proper lambda head assembly has been isolated and characterized. Phage lambda carrying this mutation is (i) unable to form plaques at...

A family of genes related to a new expression site-associated gene in Trypanosoma equiperdum.

Florent, I C, Raibaud, A, Eisen, H

Two genes, belonging to a new expression site-associated gene family of six to eight members in Trypanosoma equiperdum and Trypanosoma brucei, have been cloned from a T. equiperdum variant. One of...

Sodium butyrate inhibits myogenesis by interfering with the transcriptional activation function of MyoD and myogenin.

Johnston, L A, Tapscott, S J, Eisen, H

Sodium butyrate reversibly inhibits muscle differentiation and blocks the expression of many muscle-specific genes in both proliferating myoblasts and differentiated myotubes. We investigated the...

Alternate trans splicing in Trypanosoma equiperdum: implications for splice site selection.

Layden, R E, Eisen, H

We examined the structures of the 5' ends of mRNAs encoding variant surface glycoprotein 78 (VSG-78) and VSG-1(78) in Trypanosoma equiperdum. Several mRNA species were found for each gene, and all...

Cloning and characterization of a variant surface glycoprotein expression site from Trypanosoma equiperdum.

Raibaud, A, Buck, G, Baltz, T, Eisen, H

Variant surface glycoprotein (VSG) genes of African trypanosomes are expressed when they are inserted into one of several telomere-linked expression sites. We cloned and characterized an 11-kilobase...

DNA rearrangements and antigenic variation in Trypanosoma equiperdum: multiple expression-linked sites in independent isolates of trypanosomes expressing the same antigen.

Longacre, S, Hibner, U, Raibaud, A, Eisen, H, Baltz, T, Giroud, C, ...

African trypanosomes resist the immune response of their mammalian hosts by varying the surface glycoprotein which constitutes their antigenic identity. The molecular mechanism of this antigenic...

DNA rearrangements and antigenic variation in Trypanosoma equiperdum: expression-independent DNA rearrangements in the basic copy of a variant surface glycoprotein gene.

Longacre, S, Raibaud, A, Hibner, U, Buck, G, Eisen, H, Baltz, T, ...

Antigenic variation in Trypanosoma equiperdum is associated with the sequential expression of variant surface glycoprotein (VSG) genes in a process which involves gene duplication and transposition...

Genomic environment of variant surface antigen genes of Trypanosoma equiperdum.

Raibaud, A, Gaillard, C, Longacre, S, Hibner, U, Buck, G, Bernardi, G, ...

Expression of variant antigen genes in Trypanosoma equiperdum is accompanied by the duplication of a silent basic copy gene and the transposition of the copy to an expression site elsewhere in the...

Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells.

Keppel, F, Allet, B, Eisen, H

Chromatin proteins from erythroleukemia cells transformed by Friend virus were analyzed by sodium dodecyl sulfate/polyacrylamide gel electrophoresis. A new chromosomal protein, apparent molecular...

Modification of T-cell proliferation and interleukin 2 production in mice infected with Trypanosoma cruzi.

Harel-Bellan, A, Joskowicz, M, Fradelizi, D, Eisen, H

Acute infection of mice with Trypanosoma cruzi results in severe immunodepression and the appearance of autoimmune symptoms. In vitro, concanavalin A-stimulated T cells from spleens of infected...

Induction of spectrin in erythroleukemic cells transformed by Friend virus.

Eisen, H, Bach, R, Emery, R

The presence and accumulation in murine erythroleukemic cells transformed by Friend virus of the erythrocyte membrane-associated protein spectrin has been investigated. Spectrin was present in the...

Surface antigen in early differentiation.

Kemler, R, Babinet, C, Eisen, H, Jacob, F

Addition of Fab fragments from rabbit antiserum to surface antigen F9 to 2-cell stage mouse embryos in culture does not alter cleavage; however, the addition prevents culture does not alter cleavage;...

Exposed epitopes on a Trypanosoma equiperdum variant surface glycoprotein altered by point mutations.

Baltz, T, Giroud, C, Bringaud, F, Eisen, H, Jacquemot, C, Roth, C W

African trypanosomes are covered by a dense protein layer that is immunologically distinct on different trypanosome isolates and is termed the variant surface glycoprotein (VSG). The different VSGs...

The trypanosome VSG expression site encodes adenylate cyclase and a leucine-rich putative regulatory gene.

Ross, D T, Raibaud, A, Florent, I C, Sather, S, Gross, M K, Storm, D R, ...

African trypanosomes are protozoan parasites that evade the host immune system by varying their dense antigenic coat. The Variant Surface Glycoprotein (VSG) is expressed exclusively from...

The genomic organization and transcription of the ubiquitin genes of Trypanosoma cruzi.

Swindle, J, Ajioka, J, Eisen, H, Sanwal, B, Jacquemot, C, Browder, Z, ...

We describe here the organization of the ubiquitin genes of the parasitic protozoan Trypanosoma cruzi. T. cruzi contains greater than 100 ubiquitin coding sequences all of which are clustered into a...

Cell cycle regulation of histone H1O in CHO cells: a flow cytofluorimetric study after double staining of the cells.

Chabanas, A, Lawrence, J J, Humbert, J, Eisen, H

The regulation of histone H1O content throughout the cell cycle of non-synchronized Chinese hamster ovary (CHO) cells has been studied using double fluorescent staining and flow cytofluorometry. In...

Expression of whole and hybrid genes in Trypanosoma equiperdum antigenic variation.

Longacre, S, Eisen, H

A rapid technique involving the S1 nuclease resistance of RNA:DNA duplexes has been used to screen four Trypanosoma equiperdum variant surface glycoprotein (VSG) genes for evidence of hybrid gene...

The use of incomplete genes for the construction of a Trypanosoma equiperdum variant surface glycoprotein gene.

Roth, C W, Longacre, S, Raibaud, A, Baltz, T, Eisen, H

The expression of Trypanosoma equiperdum variant surface protein (VSG) 78 is accomplished by the duplicative transposition of silent basic copy (BC) genes into a telomer-linked expression site to...

The major 85-kDa surface antigen of the mammalian-stage forms of Trypanosoma cruzi is a family of sialidases.

Kahn, S, Colbert, T G, Wallace, J C, Hoagland, N A, Eisen, H

Trypanosoma cruzi, an intracellular protozoan parasite infecting a wide variety of vertebrates, is the agent responsible for Chagas disease in humans. An estimated 15-20 million people in South and...

Growth properties of Cellulomonas flavigena mutants affected in cellulose utilization.

Béguin, P, Eisen, H

The role of cellobiose metabolism in cellulose utilization by Cellulomonas flavigena was investigated by studying mutants unable to grow on cellobiose or cellulose. The results show that the ability...

In vitro activation of bacteriophage P2 late gene expression by extracts from phage P4-infected cells.

Gibbs, W, Eisen, H, Calendar, R

We have used a cell-free, DNA-dependent protein-synthesizing system to study the stimulation of phage P2 late gene expression by satellite phage P4. An activity is present in extracts prepared from...

Regulation of Repressor Expression in λ*

Eisen, H., Brachet, P., Silva, L. Pereira Da, Jacob, F.

A new gene in bacteriophage λ is described. The product of this gene cro prevents expression of immunity and regulates the expression of those genes to the left of the immunity region. cro- mutants...

Myeloproliferative virus, a cloned murine sarcoma virus with spleen focus-forming properties in adult mice.

Ostertag, W, Vehmeyer, K, Fagg, B, Pragnell, I B, Paetz, W, Le Bousse, M C, ...

Myeloproliferative virus, derived from Moloney sarcoma virus, causes erythroleukemia and myeloid leukemia in adult mice. This virus is also capable of fibroblast transformation in vitro. The virus...

Active late-appearing variable surface antigen genes in Trypanosoma equiperdum are constructed entirely from pseudogenes.

Roth, C, Bringaud, F, Layden, R E, Baltz, T, Eisen, H

The expression of genes coding for variable surface glycoproteins (VSGs) in Trypanosoma equiperdum is linked to duplicative transpositions of silent, basic copy sequences into telomere-linked...

Organization of four mouse lambda light chain immunoglobulin genes.

Blomberg, B, Traunecker, A, Eisen, H, Tonegawa, S

We have cloned four lambda light chain constant region (C) genes from mouse embryo DNA. Each carries its own joining (J) segment approximately 1.3 kilobases to its 5' side. The four C genes occur in...

Deletions of lambda phage locating a prm mutation within the rightward operator.

Smith, G R, Eisen, H, Reichardt, L, Hedgepeth, J

Two deletion-substitution mutations of phage lambda, spi-113 and spi-274, are shown to remove about half of the rightward operator OR. Physiological studies show that spi-113 is still repressible....

Developmental and hormonal regulation of protein H1 degrees in rodents.

Gjerset, R, Gorka, C, Hasthorpe, S, Lawrence, J J, Eisen, H

The tissue and cellular distribution and regulation of the chromatin protein H1 degrees has been examined in developing and adult mouse and in rat. The protein appears in specific cell types of solid...

Novel bacteriophage lambda mutation affecting lambda head assembly.

Georgopoulos, C P, Bisig, R, Magazin, M, Eisen, H, Court, D

A novel phage lambda mutation, called dc10, which interferes with proper lambda head assembly has been isolated and characterized. Phage lambda carrying this mutation is (i) unable to form plaques at...

A family of genes related to a new expression site-associated gene in Trypanosoma equiperdum.

Florent, I C, Raibaud, A, Eisen, H

Two genes, belonging to a new expression site-associated gene family of six to eight members in Trypanosoma equiperdum and Trypanosoma brucei, have been cloned from a T. equiperdum variant. One of...

Sodium butyrate inhibits myogenesis by interfering with the transcriptional activation function of MyoD and myogenin.

Johnston, L A, Tapscott, S J, Eisen, H

Sodium butyrate reversibly inhibits muscle differentiation and blocks the expression of many muscle-specific genes in both proliferating myoblasts and differentiated myotubes. We investigated the...

Alternate trans splicing in Trypanosoma equiperdum: implications for splice site selection.

Layden, R E, Eisen, H

We examined the structures of the 5' ends of mRNAs encoding variant surface glycoprotein 78 (VSG-78) and VSG-1(78) in Trypanosoma equiperdum. Several mRNA species were found for each gene, and all...

Cloning and characterization of a variant surface glycoprotein expression site from Trypanosoma equiperdum.

Raibaud, A, Buck, G, Baltz, T, Eisen, H

Variant surface glycoprotein (VSG) genes of African trypanosomes are expressed when they are inserted into one of several telomere-linked expression sites. We cloned and characterized an 11-kilobase...

DNA rearrangements and antigenic variation in Trypanosoma equiperdum: multiple expression-linked sites in independent isolates of trypanosomes expressing the same antigen.

Longacre, S, Hibner, U, Raibaud, A, Eisen, H, Baltz, T, Giroud, C, ...

African trypanosomes resist the immune response of their mammalian hosts by varying the surface glycoprotein which constitutes their antigenic identity. The molecular mechanism of this antigenic...

DNA rearrangements and antigenic variation in Trypanosoma equiperdum: expression-independent DNA rearrangements in the basic copy of a variant surface glycoprotein gene.

Longacre, S, Raibaud, A, Hibner, U, Buck, G, Eisen, H, Baltz, T, ...

Antigenic variation in Trypanosoma equiperdum is associated with the sequential expression of variant surface glycoprotein (VSG) genes in a process which involves gene duplication and transposition...

Genomic environment of variant surface antigen genes of Trypanosoma equiperdum.

Raibaud, A, Gaillard, C, Longacre, S, Hibner, U, Buck, G, Bernardi, G, ...

Expression of variant antigen genes in Trypanosoma equiperdum is accompanied by the duplication of a silent basic copy gene and the transposition of the copy to an expression site elsewhere in the...

Appearance of a chromatin protein during the erythroid differentiation of Friend virus-transformed cells.

Keppel, F, Allet, B, Eisen, H

Chromatin proteins from erythroleukemia cells transformed by Friend virus were analyzed by sodium dodecyl sulfate/polyacrylamide gel electrophoresis. A new chromosomal protein, apparent molecular...

Modification of T-cell proliferation and interleukin 2 production in mice infected with Trypanosoma cruzi.

Harel-Bellan, A, Joskowicz, M, Fradelizi, D, Eisen, H

Acute infection of mice with Trypanosoma cruzi results in severe immunodepression and the appearance of autoimmune symptoms. In vitro, concanavalin A-stimulated T cells from spleens of infected...

Induction of spectrin in erythroleukemic cells transformed by Friend virus.

Eisen, H, Bach, R, Emery, R

The presence and accumulation in murine erythroleukemic cells transformed by Friend virus of the erythrocyte membrane-associated protein spectrin has been investigated. Spectrin was present in the...

Surface antigen in early differentiation.

Kemler, R, Babinet, C, Eisen, H, Jacob, F

Addition of Fab fragments from rabbit antiserum to surface antigen F9 to 2-cell stage mouse embryos in culture does not alter cleavage; however, the addition prevents culture does not alter cleavage;...

Exposed epitopes on a Trypanosoma equiperdum variant surface glycoprotein altered by point mutations.

Baltz, T, Giroud, C, Bringaud, F, Eisen, H, Jacquemot, C, Roth, C W

African trypanosomes are covered by a dense protein layer that is immunologically distinct on different trypanosome isolates and is termed the variant surface glycoprotein (VSG). The different VSGs...

The trypanosome VSG expression site encodes adenylate cyclase and a leucine-rich putative regulatory gene.

Ross, D T, Raibaud, A, Florent, I C, Sather, S, Gross, M K, Storm, D R, ...

African trypanosomes are protozoan parasites that evade the host immune system by varying their dense antigenic coat. The Variant Surface Glycoprotein (VSG) is expressed exclusively from...

The genomic organization and transcription of the ubiquitin genes of Trypanosoma cruzi.

Swindle, J, Ajioka, J, Eisen, H, Sanwal, B, Jacquemot, C, Browder, Z, ...

We describe here the organization of the ubiquitin genes of the parasitic protozoan Trypanosoma cruzi. T. cruzi contains greater than 100 ubiquitin coding sequences all of which are clustered into a...

Cell cycle regulation of histone H1O in CHO cells: a flow cytofluorimetric study after double staining of the cells.

Chabanas, A, Lawrence, J J, Humbert, J, Eisen, H

The regulation of histone H1O content throughout the cell cycle of non-synchronized Chinese hamster ovary (CHO) cells has been studied using double fluorescent staining and flow cytofluorometry. In...

Expression of whole and hybrid genes in Trypanosoma equiperdum antigenic variation.

Longacre, S, Eisen, H

A rapid technique involving the S1 nuclease resistance of RNA:DNA duplexes has been used to screen four Trypanosoma equiperdum variant surface glycoprotein (VSG) genes for evidence of hybrid gene...

The use of incomplete genes for the construction of a Trypanosoma equiperdum variant surface glycoprotein gene.

Roth, C W, Longacre, S, Raibaud, A, Baltz, T, Eisen, H

The expression of Trypanosoma equiperdum variant surface protein (VSG) 78 is accomplished by the duplicative transposition of silent basic copy (BC) genes into a telomer-linked expression site to...

Interactions of rodent malaria parasites with Friend erythroleukemia cells in vitro

Eisen, H., Furusawa, M., Tanabe, K., Takada, S., Ostertag, W.

The ability of Plasmodium chabaudi and P. yoelii to bind to Friend erythroleukemia cells in vitro was examined. Extensive binding of P. yoelii and weaker binding of P. chabaudi was observed. Binding...