H. K. Kole

Specific dephosphorylation of phosphoproteins by protein-serine and -tyrosine kinases.

Kole, H K, Abdel-Ghany, M, Racker, E

Five protein kinases are shown to serve as specific phosphatases in the absence of ADP. Although the rates of hydrolysis are very slow compared to the forward phosphorylation rates under optimal...

Stimulation of phosphorylation of lipocortin at threonine residues by epidermal growth factor (EGF) and the EGF receptor: addition of protein kinase P with polylysine inhibits this effect.

Abdel-Ghany, M, Kole, H K, El Saad, M A, Racker, E

In this paper we show that epidermal growth factor (EGF) stimulates the phosphorylation of lipocortin 1, at threonine as well as at tyrosine residues, by a highly purified preparation of the EGF...

Effect of protein kinase P on phosphorylations catalyzed by the epidermal growth factor.

Abdel-Ghany, M, Kole, H K, Racker, E

Protein kinase P (PK-P) activated by histones or certain other basic compounds has been purified previously from yeast [Yanagita, Y., Abdel-Ghany, M., Raden, D., Nelson, N. & Racker, E. (1987) Proc....

Phosphonate inhibitors of protein-tyrosine and serine/threonine phosphatases.

Kole, H K, Smyth, M S, Russ, P L, Burke, T R

In all, 15 aryl-containing phosphonates have been synthesized and tested for their effect on protein-tyrosine phosphatase (PTPase) activity. Two compounds, (naphth-2-yl) difluoromethylphosphonic acid...

Specific dephosphorylation of phosphoproteins by protein-serine and -tyrosine kinases.

Kole, H K, Abdel-Ghany, M, Racker, E

Five protein kinases are shown to serve as specific phosphatases in the absence of ADP. Although the rates of hydrolysis are very slow compared to the forward phosphorylation rates under optimal...

Stimulation of phosphorylation of lipocortin at threonine residues by epidermal growth factor (EGF) and the EGF receptor: addition of protein kinase P with polylysine inhibits this effect.

Abdel-Ghany, M, Kole, H K, El Saad, M A, Racker, E

In this paper we show that epidermal growth factor (EGF) stimulates the phosphorylation of lipocortin 1, at threonine as well as at tyrosine residues, by a highly purified preparation of the EGF...

Effect of protein kinase P on phosphorylations catalyzed by the epidermal growth factor.

Abdel-Ghany, M, Kole, H K, Racker, E

Protein kinase P (PK-P) activated by histones or certain other basic compounds has been purified previously from yeast [Yanagita, Y., Abdel-Ghany, M., Raden, D., Nelson, N. & Racker, E. (1987) Proc....

Phosphonate inhibitors of protein-tyrosine and serine/threonine phosphatases.

Kole, H K, Smyth, M S, Russ, P L, Burke, T R

In all, 15 aryl-containing phosphonates have been synthesized and tested for their effect on protein-tyrosine phosphatase (PTPase) activity. Two compounds, (naphth-2-yl) difluoromethylphosphonic acid...