Integrated reactor concepts for the enzymatic kinetic synthesis of cephalexin (2002)
Nierstrasz, V.A., Bosma, R., Kroon, P.J., Tjeerdsma, P.S., DeVroom, E., ...
Integrated process concepts for enzymatic cephalexin synthesis were investigated by our group, and this article focuses on the integration of reactions and product removal during the reactions. The...
Modelling of the enzymatic kinetically controlled synthesis of cephalexin (2002)
Fretz, C.B., Berendsen, W., Moody, H.M., Roos, E.C., ...
In this study the influence of diffusion limitation on enzymatic kinetically controlled cephalexin synthesis from phenylglycine amide and 7-aminodeacetoxycephalosporinic acid (7-ADCA) was...
Integrated reactor concepts for the enzymatic kinetic synthesis of cephalexin (2002)
Nierstrasz, V.A., Bosma, R., Kroon, P.J., Tjeerdsma, P.S., Vroom, E. De, ...
Nierstrasz, V.A., Moody, H.M., Hoogschagen, M.J., Kroon, P.J., Bosma, R., ...
During enzymatic kinetic synthesis of cephalexin, an activated phenylglycine derivative (phenylglycine amide or phenylglycine methyl ester) is coupled to the nucleus 7-aminodeacetoxycephalosporanic...
Regiospecific inhibition of DNA duplication by antisense phosphate-methylated oligodeoxynucleotides.
Moody, H M, Van Genderen, M H, Koole, L H, Kocken, H J, Meijer, E M, Buck, H M
A new synthesis route for long phosphate-methylated oligodeoxynucleotides is described, which were used as antisense inhibitors of the DNA replication. Phosphate-methylated oligomers hybridize more...
Regiospecific inhibition of DNA duplication by antisense phosphate-methylated oligodeoxynucleotides.
Moody, H M, Van Genderen, M H, Koole, L H, Kocken, H J, Meijer, E M, Buck, H M
A new synthesis route for long phosphate-methylated oligodeoxynucleotides is described, which were used as antisense inhibitors of the DNA replication. Phosphate-methylated oligomers hybridize more...