Barry, A. L., Fuchs, P. C., Citron, D. M., Allen, S. D., Wexler, H. M.
The susceptibility of anaerobic bacteria to two new fluoroquinolones, PD 131628 (the bioactive form of PD 131112 or CI-990) and clinafloxacin (CI-960 or PD 127391), was determined with the agar...
In vitro activities of trovafloxacin against 557 strains of anaerobic bacteria.
Wexler, H M, Molitoris, E, Molitoris, D, Finegold, S M
The antimicrobial activity of trovafloxacin for 557 strains of anaerobic bacteria was determined by the National Committee for Clinical Laboratory Standards-approved Wadsworth agar dilution...
Cell-wall-defective variants of Fusobacterium.
Johnson, C C, Wexler, H M, Becker, S, Garcia, M, Finegold, S M
The activity of antimicrobial agents against Fusobacterium species has been reported as variable in the literature. For some strains, the inconsistency arises from difficulty in determining the...
Aldridge, K E, Wexler, H M, Sanders, C V, Finegold, S M
With 120 clinical isolates of the Bacteroides fragilis group, a comparison of rates of resistance to selected antimicrobial agents by using two susceptibility tests was performed in two medical...
Wexler, H M, Lavin, P T, Molitoris, E, Finegold, S M
A pilot study was designed to estimate the variance components in the determination of the MIC of cefoxitin for isolates of the Bacteroides fragilis group. Twenty different organisms were tested, and...
The activity of two cefoperazone-sulbactam combinations against anaerobic bacteria was tested and compared both with that of cefoperazone alone and with that of other commonly used antimicrobial...
The activity of cefotetan against 430 strains of anaerobic bacteria was compared with that of cefoxitin, ceftizoxime, clindamycin, metronidazole, and chloramphenicol. Percent susceptible values for...
In vitro efficacy of sulbactam combined with ampicillin against anaerobic bacteria.
Wexler, H M, Harris, B, Carter, W T, Finegold, S M
An ampicillin-sulbactam combination was compared with ampicillin alone, chloramphenicol, clindamycin, and metronidazole against 272 strains of anaerobic bacteria. Chloramphenicol and...
In vitro activities of three of the newer quinolones against anaerobic bacteria.
Wexler, H M, Molitoris, E, Finegold, S M
The antimicrobial activities of three new quinolone compounds, sparfloxacin, temafloxacin, and WIN 57273, against anaerobic bacteria were determined in three separate studies. The Wadsworth agar...
Summanen, P, Wexler, H M, Finegold, S M
Initial susceptibility studies of Bilophila wadsworthia indicated significant resistance to several beta-lactam antibiotics, including imipenem and cefoxitin. NO beta-lactamase production was...
In vitro activity of Bay Y3118 against anaerobic bacteria.
Wexler, H M, Molitoris, E, Finegold, S M
The antimicrobial activity of a new quinolone, Bay Y3118, was determined against 326 strains of anaerobic bacteria and compared with the activities of ampicillin-sulbactam, cefotetan, clindamycin,...
Summanen, P, Wexler, H M, Lee, K, Becker, S A, Garcia, M M, Finegold, S M
The penicillin-binding protein (PBP) patterns of six strains of Bilophila wadsworthia were investigated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis and subsequent...
Wexler, H M, Molitoris, E, Murray, P R, Washington, J, Zabransky, R J, Edelstein, P H, ...
A multilaboratory collaborative study was carried out to assess the utility of the spiral gradient endpoint (SGE) method for the determination of the antimicrobial susceptibilities of anaerobes and...
Preliminary study using species-specific oligonucleotide probe for rRNA of Bilophila wadsworthia.
Sapico, F L, Reeves, D, Wexler, H M, Duncan, J, Wilson, K H, Finegold, S M
Portions of the 16S RNA from a urease-positive Bilophila wadsworthia strain were sequenced, and a probe was constructed. The probe was end labeled with [32P]ATP and polynucleotide kinase and...
Wexler, H M, Molitoris, E, Jashnian, F, Finegold, S M
Antimicrobial susceptibility tests were performed on brucella laked blood agar with 340 isolates and 14 antimicrobial agents by the standard agar dilution technique and the spiral gradient technique...
Wexler, H M, Molitoris, E, Finegold, S M
The in vitro activities of several new beta-lactam-beta-lactamase inhibitor combinations (piperacillin plus tazobactam, ceftizoxime and cefonicid with sulbactam and clavulanic acid, and ampicillin...
In vitro activity of DU-6859a against anaerobic bacteria.
Wexler, H M, Molitoris, E, Reeves, D, Finegold, S M
The activity of a new quinolone agent, DU-6859a, against 330 strains of anaerobic bacteria was determined by using the National Committee for Clinical Laboratory Standards-approved Wadsworth brucella...
Wexler, H M, Molitoris, E, Finegold, S M
The in vitro activities of the N,N-dimethylglycylamido derivatives of minocycline (DMG-MINO) and 6-demethyl-6-deoxytetracycline (DMG-DMDOT) were compared with those of minocycline, tetracycline,...
Susceptibility testing of anaerobic bacteria: myth, magic, or method?
The demand for susceptibility testing of anaerobes has increased, yet consensus as to procedure and interpretation in this area has not been achieved. While routine testing of anaerobic isolates is...
In vitro activities of trovafloxacin against 557 strains of anaerobic bacteria.
Wexler, H M, Molitoris, E, Molitoris, D, Finegold, S M
The antimicrobial activity of trovafloxacin for 557 strains of anaerobic bacteria was determined by the National Committee for Clinical Laboratory Standards-approved Wadsworth agar dilution...
Cell-wall-defective variants of Fusobacterium.
Johnson, C C, Wexler, H M, Becker, S, Garcia, M, Finegold, S M
The activity of antimicrobial agents against Fusobacterium species has been reported as variable in the literature. For some strains, the inconsistency arises from difficulty in determining the...
Aldridge, K E, Wexler, H M, Sanders, C V, Finegold, S M
With 120 clinical isolates of the Bacteroides fragilis group, a comparison of rates of resistance to selected antimicrobial agents by using two susceptibility tests was performed in two medical...
Wexler, H M, Lavin, P T, Molitoris, E, Finegold, S M
A pilot study was designed to estimate the variance components in the determination of the MIC of cefoxitin for isolates of the Bacteroides fragilis group. Twenty different organisms were tested, and...
The activity of two cefoperazone-sulbactam combinations against anaerobic bacteria was tested and compared both with that of cefoperazone alone and with that of other commonly used antimicrobial...
The activity of cefotetan against 430 strains of anaerobic bacteria was compared with that of cefoxitin, ceftizoxime, clindamycin, metronidazole, and chloramphenicol. Percent susceptible values for...
In vitro efficacy of sulbactam combined with ampicillin against anaerobic bacteria.
Wexler, H M, Harris, B, Carter, W T, Finegold, S M
An ampicillin-sulbactam combination was compared with ampicillin alone, chloramphenicol, clindamycin, and metronidazole against 272 strains of anaerobic bacteria. Chloramphenicol and...
In vitro activities of three of the newer quinolones against anaerobic bacteria.
Wexler, H M, Molitoris, E, Finegold, S M
The antimicrobial activities of three new quinolone compounds, sparfloxacin, temafloxacin, and WIN 57273, against anaerobic bacteria were determined in three separate studies. The Wadsworth agar...
Summanen, P, Wexler, H M, Finegold, S M
Initial susceptibility studies of Bilophila wadsworthia indicated significant resistance to several beta-lactam antibiotics, including imipenem and cefoxitin. NO beta-lactamase production was...
In vitro activity of Bay Y3118 against anaerobic bacteria.
Wexler, H M, Molitoris, E, Finegold, S M
The antimicrobial activity of a new quinolone, Bay Y3118, was determined against 326 strains of anaerobic bacteria and compared with the activities of ampicillin-sulbactam, cefotetan, clindamycin,...
Summanen, P, Wexler, H M, Lee, K, Becker, S A, Garcia, M M, Finegold, S M
The penicillin-binding protein (PBP) patterns of six strains of Bilophila wadsworthia were investigated by sodium dodecyl sulfate-polyacrylamide gel electrophoresis analysis and subsequent...
Wexler, H M, Molitoris, E, Murray, P R, Washington, J, Zabransky, R J, Edelstein, P H, ...
A multilaboratory collaborative study was carried out to assess the utility of the spiral gradient endpoint (SGE) method for the determination of the antimicrobial susceptibilities of anaerobes and...
Preliminary study using species-specific oligonucleotide probe for rRNA of Bilophila wadsworthia.
Sapico, F L, Reeves, D, Wexler, H M, Duncan, J, Wilson, K H, Finegold, S M
Portions of the 16S RNA from a urease-positive Bilophila wadsworthia strain were sequenced, and a probe was constructed. The probe was end labeled with [32P]ATP and polynucleotide kinase and...
Wexler, H M, Molitoris, E, Jashnian, F, Finegold, S M
Antimicrobial susceptibility tests were performed on brucella laked blood agar with 340 isolates and 14 antimicrobial agents by the standard agar dilution technique and the spiral gradient technique...
Wexler, H M, Molitoris, E, Finegold, S M
The in vitro activities of several new beta-lactam-beta-lactamase inhibitor combinations (piperacillin plus tazobactam, ceftizoxime and cefonicid with sulbactam and clavulanic acid, and ampicillin...
In vitro activity of DU-6859a against anaerobic bacteria.
Wexler, H M, Molitoris, E, Reeves, D, Finegold, S M
The activity of a new quinolone agent, DU-6859a, against 330 strains of anaerobic bacteria was determined by using the National Committee for Clinical Laboratory Standards-approved Wadsworth brucella...
Wexler, H M, Molitoris, E, Finegold, S M
The in vitro activities of the N,N-dimethylglycylamido derivatives of minocycline (DMG-MINO) and 6-demethyl-6-deoxytetracycline (DMG-DMDOT) were compared with those of minocycline, tetracycline,...
Susceptibility testing of anaerobic bacteria: myth, magic, or method?
The demand for susceptibility testing of anaerobes has increased, yet consensus as to procedure and interpretation in this area has not been achieved. While routine testing of anaerobic isolates is...