Spenkelink, A., Mooibroek, H., Sijtsma, L., Bosch, D, ...
The chemopreventive effects of high fat microalgal oil diet on azoxymethane (AOM)-induced colonic aberrant crypt foci (ACF) were studied in male Fischer 344 rats following 8 weeks of dietary...
Enhanced substrate conversion effiency of fermentation processes (2008)
Sanders, J.P.M., Weusthuis, R.A., Mooibroek, H.
The present invention relates to the field of fermentation technology. In particular the invention relates to fermentation processes for the production of a first and a second fermentation product by...
Biorefinery as the inspired process to bulk chemicals (2007)
Sanders, J.P.M., Scott, E.L., Mooibroek, H., Weusthuis, R.A.
This paper describes several examples of knowledge-intensive technologies for the production of chemicals from biomass, which take advantage of the biomass structure in a more efficient way than the...
Roeleveld, J., Mooibroek, H., Sijtsma, L., Bino, R.J., Bosch, H.J., ...
Polyunsaturated fatty acid (PUFA) rich micro-algal oil was tested in vitro and compared with fish oil for antiproliferative properties on cancer cells in vitro. Oils derived from Crypthecodinium...
Bio-refinery as the bio-inspired process to bulk chemicals (2007)
Sanders, J.P.M., Scott, E.L., Weusthuis, R.A., Mooibroek, H.
This paper describes several examples of knowledge-intensive technologies for the production of chemicals from biomass, which take advantage of the biomass structure in a more efficient way than the...
Mooibroek, H., Oosterhuis, N., Giuseppin, M.L.F., Toonen, M.A.J., Scott, E.L., ...
Major transitions can be expected within the next few decades aiming at the reduction of pollution and global warming and at energy saving measures. For these purposes, new sustainable biorefinery...
Alink, G.M., Bino, R.J., Bosch, H.J., ...
Enhanced substrate conversion efficiency of fermentation processes (2006)
Sanders, J.P.M., Weusthuis, R.A., Mooibroek, H.
The present invention relates to the field of fermentation technology. In particular the invention relates to fermentation processes for the production of a first and a second fermentation product by...
Aarts, M.G.M., Reus, A., Mooibroek, H., Sijtsma, L., Bosch, H.J., ...
In this study the n-3 polyunsaturated fatty acids (PUFAs) eicosapentaenoic acid and docosahexaenoic acid appear to be effective inducers of electrophile-responsive element (EpRE) regulated genes,...
Cyanophycin production from nitrogen-containing chemicals obtained from biomass (2006)
Scott, E.L., Mooibroek, H., Sanders, J.P.M., Obsts, M., Steinbüchel, A.
The present invention relates to fermentation processes for the production of cyanophycin in a microorganism whereby a plant-derived nitrogen source is converted by the microorganism into...
Protamylasse, a residual compound suitable for large scale cyanophycin production (2006)
Elbahloul, Y., Sanders, J.P.M., Mooibroek, H., Steinbüchel, A.
Mcl-PHA production in Pseudomonas putida KT2442 and PhaZ-negative strains (2006)
Mooibroek, H., Wolbert, E.J.H., Dielissen, M.P.M., Weusthuis, R.A., Eggink, G.
Particle bombardment and the genetic enhancement of crops: myths and realities (2005)
Altpeter, F., Baisakh, N., Beachy, R., Bock, R., Capell, T., Christou, P., ...
DNA transfer by particle bombardment makes use of physical processes to achieve the transformation of crop plants. There is no dependence on bacteria, so the limitations inherent in organisms such as...
Particle bombardment and the genetic enhancement of crops: myths and realities (2005)
Altpeter, F., Baisakh, N., Beachy, R., Bock, R., Capell, T., Christou, P., ...
DNA transfer by particle bombardment makes use of physical processes to achieve the transformation of crop plants. There is no dependence on bacteria, so the limitations inherent in organisms such as...
Biorefinery, the bridge between agriculture and chemistry (2005)
Sanders, J.P.M., Scott, E.L., Mooibroek, H.
The depletion in fossil feedstocks, increasing oil prices and the ecological problems associated with CO2 emissions are forcing the development of alternative resources for energy (heat and...
Cloning, expression and characterisation of two tyrosinase cDNAs from Agaricus bisporus (2003)
Recourt, K, Ebbelaar, C E M, Biancone, G, Hoeberichts, F A, ...
Using primers designed on the basis of sequence homologies in the copper-binding domains for a number of plant and fungal tyrosinases, two tyrosinase encoding cDNAs were cloned from an Agaricus...
Isolation and initial characterization of microbial species with high mcl-PHA production (2002)
Wolbert, E.J.H., Gorissen, J.P.L., Dielissen, M.P.M., Weusthuis, R.A., Eggink, G., Mooibroek, H.
Heterologous expression of a fungal cellulase in Clostridium (2001)
Lopez-Contreras, A., Claassen, P., Mooibroek, H.
Growth and the production of acetone, butanol, and ethanol by Clostridium beijerinckii NCIMB 8052 on several polysaccharides and sugars were analyzed. On crystalline cellulose, growth and solvent...
Transformation of potato (Solanum tuberosum) using particle bombardment (2001)
Romano, A., Raemakers, K., Visser, R., Mooibroek, H.
Internodes, leaves and tuber slices from potato (Solanum tuberosum), genotype 1024-2, were subjected to particle bombardment. Transient expression was optimized using the uidA and the luc reporter...
Lopez-Contreras, A.M., Claassen, P.A., Mooibroek, H.
Domestic organic waste (DOW) collected in The Netherlands was analysed and used as substrate for acetone, butanol and ethanol (ABE) production. Two different samples of DOW, referred to as fresh DOW...
Alternative sources of natural rubber (2000)
Rubber (cis-1,4-polyisoprene) is one of the most important polymers naturally produced by plants because it is a strategic raw material used in more than 40,000 products, including more than 400...
Merkulov, S., Springer, J., Del Carmen, A.F., Mooibroek, H.
The squalene synthase (SQS) gene encodes a key regulatory enzyme, farnesyl-diphosphate farnesyltransferase (EC 2.5.1.21), in sterol biosynthesis. The SQS1 gene was isolated from a subgenomic library...
Cloning and expression of fungal cellulases in 'Closridium beijerinckii' NCIMB 8052 (2000)
López-Contreras, A.M., Claassen, P.A.M., Mooibroek, H., Vos, W.M.d.
Cloning and expression of fungal cellulases in 'Closridium beijerinckii' NCIMB 8052 (2000)
López-Contreras, A.M., Claassen, P.A.M., Mooibroek, H., Vos, W.M.d.
During the last decade several major breakthroughs have been achieved in mushroom biotechnology, which greatly enhanced classical mushroom breeding. DNA-based technologies such as restriction...
Mooibroek, H, Van Randen, J, Venema, G
When recipient Bacillus subtilis carrying chromosomal trimethylpsoralen cross-links were transformed, the donor marker activity decreased with the extent of cross-linking. Additional donor marker...
Mooibroek, H, Van Randen, J, Venema, G
When recipient Bacillus subtilis carrying chromosomal trimethylpsoralen cross-links were transformed, the donor marker activity decreased with the extent of cross-linking. Additional donor marker...