Ikeda, N, Mukaida, N, Kaneko, S, Fujioka, N, Su, S, Nariuchi, H, ...
Acute lethality was induced in rabbits by the sequential injection of Propionibacterium acnes and lipopolysaccharide (LPS). P. acnes induced the infiltration of inflammatory cells into the liver...
Kawasaki, H, Moriyama, M, Nariuchi, H
We analyzed the mechanism of the augmentation of endotoxin fever by human beta interferon (IFN) cross-reacting to rabbit cells in rabbits by using a purified rabbit tumor necrosis factor (RaTNF) and...
Kawasaki, H, Moriyama, M, Ohtani, Y, Naitoh, M, Nariuchi, H, Tanaka, A
Early-phase pyrogen tolerance was induced in rabbits by two consecutive daily injections of 125 ng of endotoxin per kg of body weight. The second injection of the same dose of endotoxin evoked only a...
Kawasaki, H, Moriyama, M, Ohtani, Y, Naitoh, M, Tanaka, A, Nariuchi, H
A murine monoclonal antibody to rabbit tumor necrosis factor (TNF; cachectin) was injected intravenously into an endotoxin-treated rabbit to examine the role of endogenous TNF in fever. Both early...
Ikeda, N, Mukaida, N, Kaneko, S, Fujioka, N, Su, S, Nariuchi, H, ...
Acute lethality was induced in rabbits by the sequential injection of Propionibacterium acnes and lipopolysaccharide (LPS). P. acnes induced the infiltration of inflammatory cells into the liver...
Kawasaki, H, Moriyama, M, Nariuchi, H
We analyzed the mechanism of the augmentation of endotoxin fever by human beta interferon (IFN) cross-reacting to rabbit cells in rabbits by using a purified rabbit tumor necrosis factor (RaTNF) and...
Kawasaki, H, Moriyama, M, Ohtani, Y, Naitoh, M, Nariuchi, H, Tanaka, A
Early-phase pyrogen tolerance was induced in rabbits by two consecutive daily injections of 125 ng of endotoxin per kg of body weight. The second injection of the same dose of endotoxin evoked only a...
Kawasaki, H, Moriyama, M, Ohtani, Y, Naitoh, M, Tanaka, A, Nariuchi, H
A murine monoclonal antibody to rabbit tumor necrosis factor (TNF; cachectin) was injected intravenously into an endotoxin-treated rabbit to examine the role of endogenous TNF in fever. Both early...
Takamoto, M, Wang, Z X, Watanabe, N, Matsuzawa, A, Nariuchi, H, Sugane, K
Mutant mice deficient in CD4+ T cells and their normal and heterozygous littermates were infected with Toxocara canis, and compared for eosinophilia, total and Toxocara-specific immunoglobulin E...
Takamoto, M, Kusama, Y, Takatsu, K, Nariuchi, H, Sugane, K
We studied cells in the lungs of BALB/c and BALB/c-nu/nu (nude) mice infected with Toxocara canis, which produced interleukin-5 (IL-5) in in vitro culture with larval excretory-secretory antigen...
The role of T cells in pathogenesis and protective immunity to murine malaria.
Waki, S, Uehara, S, Kanbe, K, Ono, K, Suzuki, M, Nariuchi, H
T-cell-mediated immunity to a virulent strain of Plasmodium berghei NK65 (Pb NK65) and to an attenuated derivative (Pb XAT) of the strain were examined in CBA mice by the administration of monoclonal...
Kusama, Y, Takamoto, M, Kasahara, T, Takatsu, K, Nariuchi, H, Sugane, K
We studied the mechanism of eosinophilia in BALB/c-nu/+ (nu/+) and BALB/c-nu/nu (nu/nu) mice infected with Toxocara canis. Eosinophilia with two peaks on days 11 and 21 of infection was observed in...
Kimura, K, Nakanishi, M, Ueda, M, Ueno, J, Nariuchi, H, Furukawa, S, ...
We have studied the antibody-dependent binding of macrophages to supported planar lipid monolayers containing haptenated phospholipids (Tnp-Cap-DPPE). Eight monoclonal anti-TNP IgG1s, which had...
Effect of lipopolysaccharide (LPS) on the thymocyte response to PHA: strain difference.
Mizuguchi, J, Kakiuchi, T, Nariuchi, H, Matuhasi, T
Thymocytes responded well to PHA in terms of [3H]-TdR incorporation if they were precultured in the presence of LPS, whereas fresh thymocytes or thymocytes pre-cultured in the absence of LPS...
Studies of the immunological activities of the outer membrane protein from Escherichia coli
Mohri, S., Watanabe, T., Nariuchi, H.
The outer membrane protein (OMP) prepared from Escherichia coli was found to be a potent mitogen for murine B cells and to be capable of inducing polyclonal antibody formation as well as a...
Different effect of LPS-induced macrophage factor on antibody responses to TI-1 and TI-2 antigens.
Mizuguchi, J, Kakiuchi, T, Nariuchi, H, Matuhasi, T
Effect of macrophage culture fluid (MF) on thymic independent (TI) antibody responses was examined. MF potentiated antibody responses of spleen cells to dinitrophenyl (DNP)-Ficoll and DNP-liposome,...
Wang, C-R, Hino, A, Yoshimoto, T, Nagase, H, Kato, T, Hirokawa, K, ...
Delayed-type hypersensitivity (DTH) is an important in vivo manifestation of cell-mediated immunity. We examined the DTH response to methylated bovine serum albumin of a novel mutant strain of mice...
Yanagië, H., Tomita, T., Kobayashi, H., Fujii, Y., Takahashi, T., Hasumi, K., ...
An immunoliposome containing a 10B-compound has been examined as a selective drug delivery system in boron neutron-capture therapy. Liposomes, conjugated with monoclonal antibodies specific for...