ON THE IWASAWA λ-INVARIANT OF THE CYCLOTOMIC Z2-EXTENSION OF Q ( √ p) (2009)
Takashi Fukuda, Keiichi Komatsu, In Professor, H. Ogawa
Abstract. We study the Iwasawa λ-invariant of the cyclotomic Z2-extension of Q ( √ p) for an odd prime number p which satisfies p ≡ 1(mod16)relating it to units having certain properties. We...
Distillation of Liquid Xenon to Remove Krypton (2008)
Abe, K., Hosaka, J., Iida, T., Ikeda, M., Kobayashi, K., Koshio, Y., ...
A high performance distillation system to remove krypton from xenon was constructed, and a purity level of Kr/Xe = $\sim 3 \times 10^{-12}$ was achieved. This development is crucial in facilitating...
Solar neutrino measurements in Super-Kamiokande-II (2008)
Cravens, J. P., Abe, K., Iida, T., Ishihara, K., Kameda, J., Koshio, Y., ...
The results of the second phase of the Super-Kamiokande solar neutrino measurement are presented and compared to the first phase. The solar neutrino flux spectrum and time variation as well as...
Scintillation yield of liquid xenon at room temperature (2008)
Ueshima, K., Abe, K., Iida, T., Ikeda, M., Kobayashi, K., Koshio, Y., ...
The intensity of scintillation light emission from liquid xenon at room temperature was measured. The scintillation light yield at 1 deg. was measured to be 0.64 +/- 0.02 (stat.) +/- 0.06 (sys.) of...
Search for matter-dependent atmospheric neutrino oscillations in Super-Kamiokande (2008)
Abe, K., Hayato, Y., Iida, T., Ikeda, M., Kameda, J., Koshio, Y., ...
We consider ν_μ→ν_τ oscillations in the context of the mass varying neutrino (MaVaN) model, where the neutrino mass can vary depending on the electron density along the flight path of the...
SEARCHES FOR $\beta$-ALANINE AND PYRIMIDINE TOWARD ORION-KL (2008)
Fujimori, R., Kawaguchi, K., Nakajima, T., Ogawa, H.
S. Watanebe, S. Kubota, K. Kawaguchi, Y. Kasai, and T. Momose, 61st V. B. Blagojevic, S. Petrie, and D. K. Bohme, Mon. Not. R. Astron. Soc.Y. J. Kuan, C. H. Yan, S. B. Charnley, Z. Kisiel, P....
Molecular dynamics simulation study on the structrural stabilities of polyglutamine peptides. (2008)
Ogawa, H., Nakano, M., Watanabe, H., Starikov, E.B., Rothstein, S.M., Tanaka, S.
Computational Biology and Chemistry, 32(2008) S.102-10
Journal of The Korean Astronomical Society (2007)
The Development, K. C. Xiao, H. Ogawa, H. Suzuki
A 230 GHz SIS tunnel junction receiver has been being developed for radio astronomy in Nagoya University. In this heterodyne receiver, we use a ¸ 1/3 reduced hight rectangular waveguide SIS mixer...
K. Yamazaki, H. Yamada, K. Y. Watanabe, K. Nishimura, S. Yamaguchi, M. Shoji, ...
The world’s largest superconducting helical fusion facility, the Large Helical Device (LHD), is in the final stage of the 8-year construction schedule at the National Institute for Fusion Science...
AOYAMA, M, BECKER, S, DAI, M, DAIMON, H, GORDON, L, KASAI, H, ...
An intercomparison exercise was conducted using the recently developed Reference Material for Nutrients in Seawater (RMNS). Discrepancies of reported values among laboratories were greater than the...
Guillian, G., Hosaka, J., Ishihara, K., Kameda, J., Koshio, Y., Minamino, A., ...
The relative sidereal variation in the arrival direction of primary cosmic ray nuclei of median energy 10 TeV was measured using downward, through-going muons detected with the Super-Kamiokande-I...
Projectile fragmentation reactions and production of nuclei near the neutron drip-line (2007)
Notani, M., Sakurai, H., Aoi, N., Iwasaki, H., Fukuda, N., Liu, Z., ...
The reaction mechanism of projectile fragmentation at intermediate energies has been investigated observing the target dependence of the production cross sections of very neutron-rich nuclei....
Search for the Invisible Decay of Neutrons with KamLAND (2006)
Araki, T., Enomoto, S., Furuno, K., Gando, Y., Ichimura, K., Ikeda, H., ...
The Kamioka Liquid scintillator Anti-Neutrino Detector (KamLAND) is used in a search for single neutron or two neutron intra-nuclear disappearance that would produce holes in the $\it{s}$-shell...
Citation as a Representation Process (2006)
Kryssanov, V. V., Rinaldo, F. J., Ogawa, H., Kuleshov, E.
The presented work proposes a novel approach to model the citation rate. The paper begins with a brief introduction into informetrics studies and highlights drawbacks of the contemporary approaches...
Search for the Invisible Decay of Neutrons with KamLAND (2006)
Araki, T., Enomoto, S., Furuno, K., Gando, Y., Ichimura, K., Ikeda, H., ...
The Kamioka Liquid scintillator Anti-Neutrino Detector (KamLAND) is used in a search for single neutron or two neutron intra-nuclear disappearance that would produce holes in the $\it{s}$-shell...
Nakamura, T., Ogawa, H., DileepKumar, M., Uematsu, M.
This paper presents information on concentrations, size distributions, geographical distributions and sources of water-soluble organic nitrogen (ONws) in aerosols over the East China Sea and western...
Thermo-elastic deformation of a titanium foil by ion irradiation (2006)
Tsuchida, H, Katayama, I, Jeong, SC, Ogawa, H, Sakamoto, N, Itoh, A
High-Mass Cloud Cores in the eta Carinae Giant Molecular Cloud (2005)
Yonekura, Y., Asayama, S., Kimura, K., Ogawa, H., Kanai, Y., Yamaguchi, N., ...
We carried out an unbiased survey for massive dense cores in the giant molecular cloud associated with eta Carinae with the NANTEN telescope in 12CO, 13CO, and C18O 1-0 emission lines. We identified...
Measurement of Neutrino Oscillation with KamLAND: Evidence of Spectral Distortion (2005)
Araki, T., Eguchi, K., Enomoto, S., Furuno, K., Ichimura, K., Ikeda, H., ...
We present results of a study of neutrino oscillation based on a 766 ton/year exposure of KamLAND to reactor antineutrinos. We observe 258 [overline nu ]e candidate events with energies above 3.4 MeV...
Measurement of Neutrino Oscillation with KamLAND: Evidence of Spectral Distortion (2005)
Araki, T., Eguchi, K., Enomoto, S., Furuno, K., Ichimura, K., Ikeda, H., ...
We present results of a study of neutrino oscillation based on a 766 ton/year exposure of KamLAND to reactor antineutrinos. We observe 258 [overline nu ]e candidate events with energies above 3.4 MeV...
Petersen, Poul Erik, Bourgeois, D, Bratthall, Douglas, Ogawa, H
This article describes the essential components of oral health information systems for the analysis of trends in oral disease and the evaluation of oral health programmes at the country, regional and...
Tsuchiya, T, Hirata, M, Chiba, N, Udo, R, Yoshitomi, Y, Ando, T, ...
Functional MRI Detection of Activation in the Primary Gustatory Cortices in Humans (2005)
Ogawa, H., Wakita, M., Hasegawa, K., Kobayakawa, T., Sakai, N., Hirai, T., ...
Magnetoencephalography (MEG) has recently revealed that the transitions between the parietal operculum (Pop) and the insula (area G) and the ventral end of the central sulcus (cs) were activated with...
Measurement of neutrino oscillation with Kamland: Evidence of spectral distortion (2004)
Araki, T., Eguchi, K., Enomoto, S., Furuno, K., Ichimura, K., Ikeda, H., ...
An Overview of the KamLAND 1-kiloton Liquid Scintillator (2004)
Suekane, F., Iwamoto, T., Ogawa, H., Tajima, O., Watanabe, H.
KamLAND is a massive liquid-scintillator-based neutrino detector studying low energy neutrino oscillation. The experiment has discovered a large deficit of the reactor neutrino flux with baseline of...
Yabe, A, Hirasawa, S, Kasagi, N, Kitamura, T, Nakamachi, E, Takano, Y, ...
Tsuchida, H, Katayama, I, Jeong, SC, Haba, M, Ogawa, H, Sakamoto, N, ...
Hasegawa, K., Otawa, S., Ikeda, I., Ogawa, H.
The taste coding mechanism in the cortical taste area was investigated by analyzing the responses of 59 neurons in the cortical taste area of the anesthetized rat to a mixture of the four basic...
Two cases of atopic dermatitis associated with autoimmune abnormalities (2003)
Sekigawa, I., Yoshiike, T., Iida, N., Hashimoto, H., Ogawa, H.
A preliminary methods comparison for measurement of dissolved organic nitrogen in seawater (2002)
Sharp, J.H., Rinker, K.R., Savidge, K.B., Abell, J., Benaim, J.Y., Bronk, D., ...
$\beta$-delayed proton decay of $^{24}$Si (2001)
Banerjee, V., Kubo, T., Chakrabarti, A., Sakurai, H., Bandyopadhyay, A., Morita, K., ...
$\beta$-delayed proton decay of $^{24}$Si (2001)
Banerjee, V., Kubo, T., Chakrabarti, A., Sakurai, H., Bandyopadhyay, A., Morita, K., ...
Direct measurement of a beam force exerted to a foil with a laser displacement meter (2001)
Katayama, I, Jeong, SC, Tsuchida, H, Ogawa, H, Sakamoto, N, Itoh, A
Practical stereoselective synthesis of (2,3,4,5-tetrahydro-1H-benzo[b]azepin-5-yl)acetic acid (2000)
Shinohara, T, Kondo, K, Ogawa, H, Mori, T, Nozaki, K, Hiyama, T
Evidence for particle stability of $^{31}F$ and particle instability of $^{25}N$ and $^{28}O$ (1999)
Sakuraï, H, Lukyanov, S M, Notani, M, Aoi, N, Beaumel, D, Fukuda, N, ...
Evidence for particle stability of $^{31}$F and particle instability of $^{25}$N and $^{28}$O (1999)
Sakurai, H., Lukyanov, S.M., Notani, M., Aoi, N., Beaumel, D., Fukuda, N., ...
The neutron drip line up to fluorine has been investigated by the projectile fragmentation of a 94.1A MeV /sup 40/Ar beam at the fragment separator RIPS at RIKEN. A new neutron-rich isotope, /sup...
Evidence for particle stability of $^{31}$F and particle instability of $^{25}$N and $^{28}$O (1999)
Sakurai, H., Lukyanov, S.M., Notani, M., Aoi, N., Beaumel, D., Fukuda, N., ...
The neutron drip line up to fluorine has been investigated by the projectile fragmentation of a 94.1A MeV /sup 40/Ar beam at the fragment separator RIPS at RIKEN. A new neutron-rich isotope, /sup...
Properties of incremental projection learning (1999)
We proposed a method of incremental projection learning which provides exactly the same generalization capability as that obtained by batch projection learning in the previous paper. However,...
Corrosion Behaviors of Corrosion Resistant Alloys in Acid Stimulation Environments. (1998)
A series of laboratory experiments was conducted on the corrosion behaviors in acidizing environments of corrosion resistant alloys (CRAs) such as a 13% chromium martensitic stainless steel, duplex...
Crevice Corrosion of Corrosion-Resistant Alloys in Sour Environments. (1998)
Crevice corrosion of corrosion-resistant alloys (CRAs) was studied; the crevice pH effect on initiation was investigated with the results of the linear relation between electric charge and crevice...
Solidification and Precipitation Behaviour of Inconel 718 and Waspaloy. (1998)
Murata, Y., Morinaga, M., Ogawa, H., Kato, M., Yukawa, N.
The solidification and precipitation sequence of Inconel 718 and Waspaloy was examined by means of differential thermal analysis, optical microscopy, scanning electron microscopy, electron probe...
Solidification Structure of Inconel 718 Microalloying Elements. (1998)
Murata, Y., Morinaga, M., Yukawa, N., Ogawa, H., Kato, M.
This paper concerned metals in some important way and contained information about, utilized, or discussed these subjects: basic topics: experimental materials and material types:...
KamLAND: a liquid scintillator anti-neutrino detector at the Kamioka site (1998)
Alivisatos, P, Berridge, S C, Bokor, N, Britton, C L, Bryan, W, Bugg, W M, ...
New neutron-rich isotope $^{31}$F and particle instability of $^{25}$N and $^{28}$O (1998)
Sakurai, H., Lukyanov, S.M., Notani, M., Aoi, N., Beaumel, D., Fukuda, N., ...
New neutron-rich isotope $^{31}$F and particle instability of $^{25}$N and $^{28}$O (1998)
Sakurai, H., Lukyanov, S.M., Notani, M., Aoi, N., Beaumel, D., Fukuda, N., ...
The 1000 ton liquid scintillation detector project at Kamioka (Kam-LAND) (1997)
Suekane, F, Suzuki, A, Shirai, J, Suekane, F, Hasegawa, A, Iwamoto, T, ...
Tanaka, T, Makita, H, Kawabata, K, Mori, H, Kakumoto, M, Satoh, K, ...
Neural Interaction between Cortical Taste Neurons in Rats: a Cross-correlation Analysis (1997)
In the rat cortical taste area (CTA), we recorded 31 pairs of taste neurons and seven pairs of taste and non-taste neurons, with single or double electrodes. By using a cross-correlogram (CCG) in a...
Ogawa, H, Inouye, S, Tsuji, F I, Yasuda, K, Umesono, K
The localization, trafficking, and fluorescence of Aequorea green fluorescent protein (GFP) in cultured vertebrate cells transiently transfected with GFP cDNA were studied. Fluorescence of GFP in UV...
Okeke, C. N., Tsuboi, R., Kawai, M., Ogawa, H.
Keratin particles impregnated with amorolfine or clotrimazole in serial doubling dilutions (64 to 0.125 μg/ml) were used to evaluate the activities of these agents against 20 isolates each of...
Katahira, R, Katahira, M, Yamashita, Y, Ogawa, H, Kyogoku, Y, Yoshida, M
Aureolic acid group compounds, such as chromomycin A3(CHM) and mithramycin (MIT), are known as antitumor drugs. Recently we isolated a novel aureolic acid group antitumor drug, UCH9, from...
Subcutaneous Phaeohyphomycosis Caused by Veronaea botryosa in the People’s Republic of China
Matsushita, A., Jilong, L., Hiruma, M., Kobayashi, M., Matsumoto, T., Ogawa, H., ...
The second case of phaeohyphomycosis caused by Veronaea botryosa in China, in a 12-year-old boy from Jiangsu Province, is presented. Based on direct examination of the scrapings from crusted lesions;...
Subcutaneous Phaeohyphomycosis Caused by Veronaea botryosa in the People's Republic of China
Matsushita, A., Jilong, L., Hiruma, M., Kobayashi, M., Matsumoto, T., Ogawa, H., ...
Induction of an extracellular esterase from Candida albicans and some of its properties.
Tsuboi, R, Komatsuzaki, H, Ogawa, H
An extracellular esterase from Candida albicans A-714 was found to be induced in a medium containing 0.7% yeast nitrogen base and 2.5% Tween 80 (polyoxyethylenesorbitan compounds). Enzyme activity,...
In vitro and in vivo activities of DN-9550, a new broad-spectrum cephalosporin.
Une, T, Otani, T, Sato, M, Ikeuchi, T, Osada, Y, Ogawa, H, ...
DN-9550 [(6R, 7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(1H-imidazol-4-yl) methoxyiminoacetamido]-3-[(1-pyridinio)methyl]-8-oxo-5-thia -1-azabicyclo...
In vitro and in vivo activity of DL-8280, a new oxazine derivative.
Sato, K, Matsuura, Y, Inoue, M, Une, T, Osada, Y, Ogawa, H, ...
DL-8280, 9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H- pyrido-(1,2,3-de)1,4-benzoxazine-6-carboxylic acid, is a new nalidixic acid analog with a broad spectrum of antibacterial...
Antimycoplasmal activity of ofloxacin (DL-8280).
Ofloxacin (DL-8280; (+/-)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- pipera-zinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid) showed a broader spectrum and a greater potency of...
Isolation and properties of extracellular proteinases from Sporothrix schenckii.
Tsuboi, R, Sanada, T, Takamori, K, Ogawa, H
Sporothrix schenckii, mainly in the yeast form of the organism, produced extracellular proteinases when cultivated in liquid media containing albumin or collagen as a nitrogen source, but did not do...
Tsuboi, R, Ko, I, Takamori, K, Ogawa, H
A keratinolytic proteinase with enzyme activity at acidic pH was isolated from culture filtrates of Trichophyton mentagrophytes, a major pathogenic fungus of dermatophytosis. The molecular weight of...
Tsuboi, R, Sanada, T, Ogawa, H
Sporothrix schenckii produces two extracellular proteinases in albumin- or collagen-supplemented unbuffered liquid medium. Proteinase I had an optimal pH of 6.0, and its activity was strongly...
Ogawa, H, Date, T, Gomi, T, Konishi, K, Pitot, H C, Cantoni, G L, ...
Five cDNA clones encoding rat liver guanidinoacetate methyltransferase (S-adenosyl-L-methionine: guanidinoacetate N-methyltransferase, EC 2.1.1.2) were isolated from a lambda gt11 cDNA library by use...
Ogawa, H, Miller, D A, Dunn, T, Su, Y, Burcham, J M, Peraino, C, ...
Rat serine dehydratase cDNA clones were isolated from a lambda gt11 cDNA library on the basis of their reactivity with monospecific immunoglobulin to the purified enzyme. Using the cDNA insert from a...
Yasue, H, Obata, K, Okumura, K, Kurose, M, Ogawa, H, Matsuyama, K, ...
To examine whether atrial natriuretic polypeptide (ANP) is released from the left ventricle in patients with dilated cardiomyopathy (DCM) we measured plasma ANP level in the aortic root (Ao), the...
Ogawa, H, Gomi, T, Mueckler, M M, Fujioka, M, Backlund, P S, Aksamit, R R, ...
Rat liver cDNA libraries constructed in lambda gt11 were screened for reactivity with polyclonal antibodies to native S-adenosyl-L-homocysteine (AdoHcy) hydrolase (adenosylhomocysteinase; EC...
A chicken RAD51 homologue is expressed at high levels in lymphoid and reproductive organs.
Bezzubova, O, Shinohara, A, Mueller, R G, Ogawa, H, Buerstedde, J M
Comparisons of the amino acid sequences of three yeast RecA-like proteins, Rad51 and DMC1 from S.cerevisiae and Rad51 from S.pombe, revealed several highly conserved regions. Degenerated...
A new mutant, which was sensitive to both methyl-methanesulfonate (MMS) and ultra-violet light (UV) and defective in meiotic recombination, was isolated from Saccharomyces cerevisiae. The gene, ESR1,...
The MRE4 gene was cloned by complementation of the defects of meiotic recombination and haploidization in an mre4-1 mutant. Disruption of MRE4 resulted in reduced meiotic recombination and spore...
Purification and characterization of an extracellular proteinase from Hendersonula toruloidea.
Rojanavanich, V, Yoshiike, T, Tsuboi, R, Takamori, K, Ogawa, H
An extracellular proteinase from a fast-growing strain of Hendersonula toruloidea was demonstrated when it was cultivated in liquid medium containing bovine serum albumin as the sole nitrogen source....
Kojima, M, Suzuki, M, Morita, T, Ogawa, T, Ogawa, H, Tada, M
Interaction of RecA protein of Escherichia coli with pBR322 DNA modified by N-hydroxy-2-acetylaminofluorene (N-OH-AAF) and 4-hydroxyaminoquinoline 1-oxide (4HAQO) was investigated. RecA protein bound...
Sequence of the rat serine dehydratase gene.
Ogawa, H, Fujioka, M, Matsuda, Y, Su, Y, Dunn, T, Miller, D A, ...
Osada, Y, Mitsuyama, M, Une, T, Matsumoto, K, Otani, T, Satoh, M, ...
By subcutaneous treatment with an aqueous solution of 6-O-stearoyl-N-acetylmuramyl-L-alanyl-D-isoglutamine [6-O-CH3-(CH2)16-CO-MurNAc-L-Ala-D-isoGln] [referred to here as L18-MDP(Ala)], an...
Polymorphonuclear leukocyte activation by a synthetic muramyl dipeptide analog.
Osada, Y, Otani, T, Sato, M, Une, T, Matsumoto, K, Ogawa, H
N alpha-(N-Acetylmuramyl-L-alanyl-D-isoglutaminyl)-N epsilon -stearoyl-L-lysine, a synthetic derivative of muramyl dipeptide, stimulated the chemotactic mobility, phagocytic activity, and superoxide...
Matsumoto, K, Otani, T, Une, T, Osada, Y, Ogawa, H, Azuma, I
Stimulation of resistance to infection induced by the analogs of muramyl dipeptide (MDP) having substituted functions in the gamma-carboxyl group of D-isoglutamyl residue was examined in experimental...
Organization of the recA gene of Escherichia coli.
The restriction map of a BamHI DNA fragment that contains the recA gene of Escherichia coli has been established and a large portion of the fragment's nucleotide sequence has been determined. The...
Matsumoto, K, Ogawa, H, Kusama, T, Nagase, O, Sawaki, N, Inage, M, ...
The experimental system utilized in investigating the correlation between the chemical structures of muramyl peptides and their protective activities in the sepsis type of systemic infections caused...
Primary structure of the RAD52 gene in Saccharomyces cerevisiae.
The RAD52 gene of Saccharomyces cerevisiae, which is involved in genetic recombination and DNA repair, was cloned by transformation of rad52-1 mutant cells to methyl methanesulfonate resistance with...
Structural analysis of the umu operon required for inducible mutagenesis in Escherichia coli.
Kitagawa, Y, Akaboshi, E, Shinagawa, H, Horii, T, Ogawa, H, Kato, T
The nucleotide sequence of a 2.8-kilobase fragment of the Escherichia coli chromosome containing the umuDC genes has been determined. The DNA sequence specifies two open reading frames of 417 and...
Christiano, A M, Suga, Y, Greenspan, D S, Ogawa, H, Uitto, J
Epidermolysis bullosa (EB) is a group of heritable mechano-bullous skin diseases classified into three major categories on the basis of the level of tissue separation within the dermal-epidermal...
Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death.
Sonoda, E, Sasaki, M S, Buerstedde, J M, Bezzubova, O, Shinohara, A, Ogawa, H, ...
Yeast rad51 mutants are viable, but extremely sensitive to gamma-rays due to defective repair of double-strand breaks. In contrast, disruption of the murine RAD51 homologue is lethal, indicating an...
The MER3 gene is identified as a novel meiosis-specific gene, whose transcript is spliced in an MRE2/MER1-dependent manner. The predicted Mer3 protein contains the seven motifs characteristic of the...
Ogawa, H, Gomi, T, Takata, Y, Date, T, Fujioka, M
An expression vector was constructed that produced rat glycine N-methyltransferase in Escherichia coli. Recombinant glycine N-methyltransferase was purified to homogeneity by DEAE-cellulose and...
Identification of the major allergens in wheat flour responsible for baker's asthma.
Amano, M, Ogawa, H, Kojima, K, Kamidaira, T, Suetsugu, S, Yoshihama, M, ...
Baker's asthma, a typical occupational allergic disease, is a serious problem in the food industries. In this study, purification and identification of major allergens recognized by IgEs in sera of...
Lamellar stacking in three-dimensional crystals of Ca(2+)-ATPase from sarcoplasmic reticulum.
Cheong, G W, Young, H S, Ogawa, H, Toyoshima, C, Stokes, D L
Electron microscopy of multilamellar crystals of CA(2+)-ATPase currently offers the best opportunity for obtaining a high-resolution structure of this ATP-driven ion pump. Under certain conditions...
Ogawa, H, Stokes, D L, Sasabe, H, Toyoshima, C
We have used multilamellar crystals of the ATP-driven calcium pump from sarcoplasmic reticulum to address the structural effects of calcium binding to the enzyme. They are stacks of disk-shaped...
In vivo release of glutamate in nucleus tractus solitarii of the rat during hypoxia.
Mizusawa, A, Ogawa, H, Kikuchi, Y, Hida, W, Kurosawa, H, Okabe, S, ...
1. An attempt has been made to test the hypothesis that, in the caudal part of nucleus tractus solitarii (NTS) where carotid sinus nerve (CSN) afferents project, L-glutamate (Glut) modulates the...
Ikeda, I, Yamashita, Y, Ono, T, Ogawa, H
1. The fluorescent dye quinacrine which accumulates in Merkel cells in touch domes was administered to rats and the effects of excitation light irradiation on the mechanical responses of slowly...
Nitric oxide as a retrograde messenger in the nucleus tractus solitarii of rats during hypoxia.
Ogawa, H, Mizusawa, A, Kikuchi, Y, Hida, W, Miki, H, Shirato, K
1. We examined the role of nitric oxide (NO) in respiratory regulation in the nucleus tractus solitarii (NTS), where L-glutamate release associated with peripheral chemoreceptor activation modulates...
Role of the parabrachial nucleus in ventilatory responses of awake rats.
Mizusawa, A, Ogawa, H, Kikuchi, Y, Hida, W, Shirato, K
1. The parabrachial nucleus (PBN) is thought to play an important role in cardiorespiratory control. However, the circumstances under which it affects ventilation are still not known. The purpose of...
Voltage-dependent currents in isolated single Merkel cells of rats.
Yamashita, Y, Akaike, N, Wakamori, M, Ikeda, I, Ogawa, H
1. Merkel cells were dissociated enzymatically from the footpad epidermis of 10- to 20-day-old rats pretreated with fluorescent dye, quinacrine, for purposes of staining. The fluorescent Merkel cells...
1. A total of fifty-four mechanoreceptor afferent units with fast conducting axons in the tibial nerve innervating the glabrous skin of the hind leg were isolated in anaesthetized cats. 2. Twenty-six...
Gustatory impulse discharges in response to saccharin in rats and hamsters
Ogawa, H., Sato, M., Yamashita, S.
1. Impulse discharges produced by saccharin sodium as well as four basic gustatory stimuli were recorded in chorda tympani fibres of rats and hamsters.
Ogawa, H., Sato, M., Yamashita, S.
1. Impulse discharges in single chorda tympani fibres of rats and hamsters in response to gustatory stimuli representing the four basic qualities of taste as well as to cooling and warming of the...
Identification of New Genes Required for Meiotic Recombination in Saccharomyces Cerevisiae
Ajimura, M., Leem, S. H., Ogawa, H.
Mutants defective in meiotic recombination were isolated from a disomic haploid strain of Saccharomyces cerevisiae by examining recombination within the leu2 and his4 heteroalleles located on...
A temperature-sensitive mre11-1 mutation of Saccharomyces cerevisiae causes defects in meiotic recombination and DNA repair during vegetative grwoth at a restrictive temperature. We cloned the MRE11...
Shinohara, M., Shita-Yamaguchi, E., Buerstedde, J. M., Shinagawa, H., Ogawa, H., Shinohara, A.
The RAD54 gene, which encodes a protein in the SWI2/SNF2 family, plays an important role in recombination and DNA repair in Saccharomyces cerevisiae. The yeast genome project revealed a homologue of...
Genetic studies to characterize the origin of the mutation in placental aromatase deficiency.
Harada, N, Ogawa, H, Shozu, M, Yamada, K
Placental aromatase deficiency has recently been shown to be due to expression of RNA transcripts encoding abnormal aromatase molecules with 29 extra amino acids. To establish whether this aromatase...
Ogawa, H, Inouye, S, Tsuji, F I, Yasuda, K, Umesono, K
The localization, trafficking, and fluorescence of Aequorea green fluorescent protein (GFP) in cultured vertebrate cells transiently transfected with GFP cDNA were studied. Fluorescence of GFP in UV...
Okeke, C. N., Tsuboi, R., Kawai, M., Ogawa, H.
Keratin particles impregnated with amorolfine or clotrimazole in serial doubling dilutions (64 to 0.125 μg/ml) were used to evaluate the activities of these agents against 20 isolates each of...
Katahira, R, Katahira, M, Yamashita, Y, Ogawa, H, Kyogoku, Y, Yoshida, M
Aureolic acid group compounds, such as chromomycin A3(CHM) and mithramycin (MIT), are known as antitumor drugs. Recently we isolated a novel aureolic acid group antitumor drug, UCH9, from...
Subcutaneous Phaeohyphomycosis Caused by Veronaea botryosa in the People’s Republic of China
Matsushita, A., Jilong, L., Hiruma, M., Kobayashi, M., Matsumoto, T., Ogawa, H., ...
The second case of phaeohyphomycosis caused by Veronaea botryosa in China, in a 12-year-old boy from Jiangsu Province, is presented. Based on direct examination of the scrapings from crusted lesions;...
Subcutaneous Phaeohyphomycosis Caused by Veronaea botryosa in the People's Republic of China
Matsushita, A., Jilong, L., Hiruma, M., Kobayashi, M., Matsumoto, T., Ogawa, H., ...
Induction of an extracellular esterase from Candida albicans and some of its properties.
Tsuboi, R, Komatsuzaki, H, Ogawa, H
An extracellular esterase from Candida albicans A-714 was found to be induced in a medium containing 0.7% yeast nitrogen base and 2.5% Tween 80 (polyoxyethylenesorbitan compounds). Enzyme activity,...
In vitro and in vivo activities of DN-9550, a new broad-spectrum cephalosporin.
Une, T, Otani, T, Sato, M, Ikeuchi, T, Osada, Y, Ogawa, H, ...
DN-9550 [(6R, 7R)-7-[(Z)-2-(2-aminothiazol-4-yl)-2-(1H-imidazol-4-yl) methoxyiminoacetamido]-3-[(1-pyridinio)methyl]-8-oxo-5-thia -1-azabicyclo...
In vitro and in vivo activity of DL-8280, a new oxazine derivative.
Sato, K, Matsuura, Y, Inoue, M, Une, T, Osada, Y, Ogawa, H, ...
DL-8280, 9-fluoro-3-methyl-10-(4-methyl-1-piperazinyl)-7-oxo-2,3-dihydro-7H- pyrido-(1,2,3-de)1,4-benzoxazine-6-carboxylic acid, is a new nalidixic acid analog with a broad spectrum of antibacterial...
Antimycoplasmal activity of ofloxacin (DL-8280).
Ofloxacin (DL-8280; (+/-)-9-fluoro-2,3-dihydro-3-methyl-10-(4-methyl-1- pipera-zinyl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid) showed a broader spectrum and a greater potency of...
Isolation and properties of extracellular proteinases from Sporothrix schenckii.
Tsuboi, R, Sanada, T, Takamori, K, Ogawa, H
Sporothrix schenckii, mainly in the yeast form of the organism, produced extracellular proteinases when cultivated in liquid media containing albumin or collagen as a nitrogen source, but did not do...
Tsuboi, R, Ko, I, Takamori, K, Ogawa, H
A keratinolytic proteinase with enzyme activity at acidic pH was isolated from culture filtrates of Trichophyton mentagrophytes, a major pathogenic fungus of dermatophytosis. The molecular weight of...
Tsuboi, R, Sanada, T, Ogawa, H
Sporothrix schenckii produces two extracellular proteinases in albumin- or collagen-supplemented unbuffered liquid medium. Proteinase I had an optimal pH of 6.0, and its activity was strongly...
Ogawa, H, Date, T, Gomi, T, Konishi, K, Pitot, H C, Cantoni, G L, ...
Five cDNA clones encoding rat liver guanidinoacetate methyltransferase (S-adenosyl-L-methionine: guanidinoacetate N-methyltransferase, EC 2.1.1.2) were isolated from a lambda gt11 cDNA library by use...
Ogawa, H, Miller, D A, Dunn, T, Su, Y, Burcham, J M, Peraino, C, ...
Rat serine dehydratase cDNA clones were isolated from a lambda gt11 cDNA library on the basis of their reactivity with monospecific immunoglobulin to the purified enzyme. Using the cDNA insert from a...
Yasue, H, Obata, K, Okumura, K, Kurose, M, Ogawa, H, Matsuyama, K, ...
To examine whether atrial natriuretic polypeptide (ANP) is released from the left ventricle in patients with dilated cardiomyopathy (DCM) we measured plasma ANP level in the aortic root (Ao), the...
Ogawa, H, Gomi, T, Mueckler, M M, Fujioka, M, Backlund, P S, Aksamit, R R, ...
Rat liver cDNA libraries constructed in lambda gt11 were screened for reactivity with polyclonal antibodies to native S-adenosyl-L-homocysteine (AdoHcy) hydrolase (adenosylhomocysteinase; EC...
A chicken RAD51 homologue is expressed at high levels in lymphoid and reproductive organs.
Bezzubova, O, Shinohara, A, Mueller, R G, Ogawa, H, Buerstedde, J M
Comparisons of the amino acid sequences of three yeast RecA-like proteins, Rad51 and DMC1 from S.cerevisiae and Rad51 from S.pombe, revealed several highly conserved regions. Degenerated...
A new mutant, which was sensitive to both methyl-methanesulfonate (MMS) and ultra-violet light (UV) and defective in meiotic recombination, was isolated from Saccharomyces cerevisiae. The gene, ESR1,...
The MRE4 gene was cloned by complementation of the defects of meiotic recombination and haploidization in an mre4-1 mutant. Disruption of MRE4 resulted in reduced meiotic recombination and spore...
Purification and characterization of an extracellular proteinase from Hendersonula toruloidea.
Rojanavanich, V, Yoshiike, T, Tsuboi, R, Takamori, K, Ogawa, H
An extracellular proteinase from a fast-growing strain of Hendersonula toruloidea was demonstrated when it was cultivated in liquid medium containing bovine serum albumin as the sole nitrogen source....
Kojima, M, Suzuki, M, Morita, T, Ogawa, T, Ogawa, H, Tada, M
Interaction of RecA protein of Escherichia coli with pBR322 DNA modified by N-hydroxy-2-acetylaminofluorene (N-OH-AAF) and 4-hydroxyaminoquinoline 1-oxide (4HAQO) was investigated. RecA protein bound...
Sequence of the rat serine dehydratase gene.
Ogawa, H, Fujioka, M, Matsuda, Y, Su, Y, Dunn, T, Miller, D A, ...
Osada, Y, Mitsuyama, M, Une, T, Matsumoto, K, Otani, T, Satoh, M, ...
By subcutaneous treatment with an aqueous solution of 6-O-stearoyl-N-acetylmuramyl-L-alanyl-D-isoglutamine [6-O-CH3-(CH2)16-CO-MurNAc-L-Ala-D-isoGln] [referred to here as L18-MDP(Ala)], an...
Polymorphonuclear leukocyte activation by a synthetic muramyl dipeptide analog.
Osada, Y, Otani, T, Sato, M, Une, T, Matsumoto, K, Ogawa, H
N alpha-(N-Acetylmuramyl-L-alanyl-D-isoglutaminyl)-N epsilon -stearoyl-L-lysine, a synthetic derivative of muramyl dipeptide, stimulated the chemotactic mobility, phagocytic activity, and superoxide...
Matsumoto, K, Otani, T, Une, T, Osada, Y, Ogawa, H, Azuma, I
Stimulation of resistance to infection induced by the analogs of muramyl dipeptide (MDP) having substituted functions in the gamma-carboxyl group of D-isoglutamyl residue was examined in experimental...
Organization of the recA gene of Escherichia coli.
The restriction map of a BamHI DNA fragment that contains the recA gene of Escherichia coli has been established and a large portion of the fragment's nucleotide sequence has been determined. The...
Matsumoto, K, Ogawa, H, Kusama, T, Nagase, O, Sawaki, N, Inage, M, ...
The experimental system utilized in investigating the correlation between the chemical structures of muramyl peptides and their protective activities in the sepsis type of systemic infections caused...
Primary structure of the RAD52 gene in Saccharomyces cerevisiae.
The RAD52 gene of Saccharomyces cerevisiae, which is involved in genetic recombination and DNA repair, was cloned by transformation of rad52-1 mutant cells to methyl methanesulfonate resistance with...
Structural analysis of the umu operon required for inducible mutagenesis in Escherichia coli.
Kitagawa, Y, Akaboshi, E, Shinagawa, H, Horii, T, Ogawa, H, Kato, T
The nucleotide sequence of a 2.8-kilobase fragment of the Escherichia coli chromosome containing the umuDC genes has been determined. The DNA sequence specifies two open reading frames of 417 and...
Christiano, A M, Suga, Y, Greenspan, D S, Ogawa, H, Uitto, J
Epidermolysis bullosa (EB) is a group of heritable mechano-bullous skin diseases classified into three major categories on the basis of the level of tissue separation within the dermal-epidermal...
In vivo release of glutamate in nucleus tractus solitarii of the rat during hypoxia.
Mizusawa, A, Ogawa, H, Kikuchi, Y, Hida, W, Kurosawa, H, Okabe, S, ...
1. An attempt has been made to test the hypothesis that, in the caudal part of nucleus tractus solitarii (NTS) where carotid sinus nerve (CSN) afferents project, L-glutamate (Glut) modulates the...
Ikeda, I, Yamashita, Y, Ono, T, Ogawa, H
1. The fluorescent dye quinacrine which accumulates in Merkel cells in touch domes was administered to rats and the effects of excitation light irradiation on the mechanical responses of slowly...
Nitric oxide as a retrograde messenger in the nucleus tractus solitarii of rats during hypoxia.
Ogawa, H, Mizusawa, A, Kikuchi, Y, Hida, W, Miki, H, Shirato, K
1. We examined the role of nitric oxide (NO) in respiratory regulation in the nucleus tractus solitarii (NTS), where L-glutamate release associated with peripheral chemoreceptor activation modulates...
Role of the parabrachial nucleus in ventilatory responses of awake rats.
Mizusawa, A, Ogawa, H, Kikuchi, Y, Hida, W, Shirato, K
1. The parabrachial nucleus (PBN) is thought to play an important role in cardiorespiratory control. However, the circumstances under which it affects ventilation are still not known. The purpose of...
Rad51-deficient vertebrate cells accumulate chromosomal breaks prior to cell death.
Sonoda, E, Sasaki, M S, Buerstedde, J M, Bezzubova, O, Shinohara, A, Ogawa, H, ...
Yeast rad51 mutants are viable, but extremely sensitive to gamma-rays due to defective repair of double-strand breaks. In contrast, disruption of the murine RAD51 homologue is lethal, indicating an...
The MER3 gene is identified as a novel meiosis-specific gene, whose transcript is spliced in an MRE2/MER1-dependent manner. The predicted Mer3 protein contains the seven motifs characteristic of the...
Voltage-dependent currents in isolated single Merkel cells of rats.
Yamashita, Y, Akaike, N, Wakamori, M, Ikeda, I, Ogawa, H
1. Merkel cells were dissociated enzymatically from the footpad epidermis of 10- to 20-day-old rats pretreated with fluorescent dye, quinacrine, for purposes of staining. The fluorescent Merkel cells...
Identification of New Genes Required for Meiotic Recombination in Saccharomyces Cerevisiae
Ajimura, M., Leem, S. H., Ogawa, H.
Mutants defective in meiotic recombination were isolated from a disomic haploid strain of Saccharomyces cerevisiae by examining recombination within the leu2 and his4 heteroalleles located on...
A temperature-sensitive mre11-1 mutation of Saccharomyces cerevisiae causes defects in meiotic recombination and DNA repair during vegetative grwoth at a restrictive temperature. We cloned the MRE11...
Shinohara, M., Shita-Yamaguchi, E., Buerstedde, J. M., Shinagawa, H., Ogawa, H., Shinohara, A.
The RAD54 gene, which encodes a protein in the SWI2/SNF2 family, plays an important role in recombination and DNA repair in Saccharomyces cerevisiae. The yeast genome project revealed a homologue of...
Ogawa, H, Gomi, T, Takata, Y, Date, T, Fujioka, M
An expression vector was constructed that produced rat glycine N-methyltransferase in Escherichia coli. Recombinant glycine N-methyltransferase was purified to homogeneity by DEAE-cellulose and...
Identification of the major allergens in wheat flour responsible for baker's asthma.
Amano, M, Ogawa, H, Kojima, K, Kamidaira, T, Suetsugu, S, Yoshihama, M, ...
Baker's asthma, a typical occupational allergic disease, is a serious problem in the food industries. In this study, purification and identification of major allergens recognized by IgEs in sera of...
Lamellar stacking in three-dimensional crystals of Ca(2+)-ATPase from sarcoplasmic reticulum.
Cheong, G W, Young, H S, Ogawa, H, Toyoshima, C, Stokes, D L
Electron microscopy of multilamellar crystals of CA(2+)-ATPase currently offers the best opportunity for obtaining a high-resolution structure of this ATP-driven ion pump. Under certain conditions...
1. A total of fifty-four mechanoreceptor afferent units with fast conducting axons in the tibial nerve innervating the glabrous skin of the hind leg were isolated in anaesthetized cats. 2. Twenty-six...
Ogawa, H, Stokes, D L, Sasabe, H, Toyoshima, C
We have used multilamellar crystals of the ATP-driven calcium pump from sarcoplasmic reticulum to address the structural effects of calcium binding to the enzyme. They are stacks of disk-shaped...
Gustatory impulse discharges in response to saccharin in rats and hamsters
Ogawa, H., Sato, M., Yamashita, S.
1. Impulse discharges produced by saccharin sodium as well as four basic gustatory stimuli were recorded in chorda tympani fibres of rats and hamsters.
Ogawa, H., Sato, M., Yamashita, S.
1. Impulse discharges in single chorda tympani fibres of rats and hamsters in response to gustatory stimuli representing the four basic qualities of taste as well as to cooling and warming of the...
Genetic studies to characterize the origin of the mutation in placental aromatase deficiency.
Harada, N, Ogawa, H, Shozu, M, Yamada, K
Placental aromatase deficiency has recently been shown to be due to expression of RNA transcripts encoding abnormal aromatase molecules with 29 extra amino acids. To establish whether this aromatase...
Suchi, M, Mizuno, H, Kawai, Y, Tsuboi, T, Sumi, S, Okajima, K, ...
Uridine monophosphate (UMP) synthase is a bifunctional enzyme catalyzing the last two steps of de novo pyrimidine biosynthesis, orotate phosphoribosyltransferase (OPRT) and orotidine-5'-monophosphate...
Kobayashi, T, Ogawa, H, Kasahara, M, Shiozawa, Z, Matsuzawa, T
We describe here evidence of congenital enzyme mistargeting induced not by abnormalities in the signal sequence. We examined the molecular mechanism of hereditary ornithine aminotransferase (OAT)...
Classification of non-Q-wave myocardial infarction according to electrocardiographic changes.
Ogawa, H, Hiramori, K, Haze, K, Saito, M, Sumiyoshi, T, Fukami, K, ...
The characteristics of 93 patients in whom electrocardiographic recordings were obtained within 12 hours of the onset of non-Q-wave myocardial infarction were studied. Patients were divided into the...
Circadian variation in fibrinolytic activity in patients with variant angina.
Masuda, T., Ogawa, H., Miyao, Y., Yu, Q., Misumi, I., Sakamoto, T., ...
BACKGROUND--Coronary artery spasm induces activation of the coagulation system. Turnover and maintenance of thrombus depend not only on formation but also on lysis. The relation between coronary...
In vitro X-ray irradiation of human peripheral blood T lymphocytes enhances suppressor function.
We studied the effect of in vitro X-ray irradiation on human peripheral blood T lymphocytes, with regard to their suppressor activity related to the concanavalin A (Con A)-induced suppressor system....
We attempted to elucidate the mechanism of action of T cell growth factor (TCGF)-expanded cells after stimulation with concanavalin A (Con A), a process which reduces the severity of adjuvant...
Suppression of adjuvant arthritis in rats by transfer of cultured spleen cells.
We studied the in vivo effect of transfer of nonspecific suppressor spleen cells into syngeneic Lewis rats. The rats were immunized with Freund's adjuvant on day 0, and then given 5 X 10(7) cells on...
Transfer of spleen cells expanded by T cell growth factor suppresses arthritis induced in rats.
The effects of transfer of T cell growth factor (TCGF)-expanded spleen cells after concanavalin A (Con A) stimulation into syngeneic Lewis rats were studied. The recipient rats were immunized with...
Comparative study of eosinophil and neutrophil chemotaxis and enzyme release.
Ogawa, H., Kunkel, S. L., Fantone, J. C., Ward, P. A.
It has been well documented that both natural and synthetic chemotactic peptides can induce lysosomal enzyme release from neutrophils treated with cytochalasin B. These same peptides are also potent...
Pancreatic B-cell function is altered by oxidative stress induced by acute hyperglycaemia
Miyazaki, Y, Kawano, H, Yoshida, T, Miyamoto, S, Hokamaki, J, Nagayoshi, Y, ...
Involvement of macrophage migration inhibitory factor (MIF) in the mechanism of tumor cell growth.
Takahashi, N., Nishihira, J., Sato, Y., Kondo, M., Ogawa, H., Ohshima, T., ...
BACKGROUND: Macrophage migration inhibitory factor (MIF) was recently rediscovered as a cytokine, pituitary hormone, and glucocorticoid-induced immunomodulator. MIF is constitutively expressed in...
Role of hypoxia on increased blood pressure in patients with obstructive sleep apnoea.
Okabe, S, Hida, W, Kikuchi, Y, Taguchi, O, Ogawa, H, Mizusawa, A, ...
BACKGROUND--Cyclical changes in systemic blood pressure occur during apnoeic episodes in patients with obstructive sleep apnoea (OSA). Although several factors including arterial hypoxaemia,...
Placental transfer and tissue distribution of 14C-styrene: an autoradiographic study in mice.
Kishi, R, Katakura, Y, Okui, T, Ogawa, H, Ikeda, T, Miyake, H
The distribution of 14C-styrene was studied in the pregnant mouse using a whole body low temperature autoradiographic technique. In unsectioned tissues studied by liquid scintillation the...
Comparison of atopic cough with cough variant asthma: is atopic cough a precursor of asthma?
Fujimura, M, Ogawa, H, Nishizawa, Y, Nishi, K
Background: We have described a group of patients who present with isolated chronic bronchodilator resistant non-productive cough with an atopic constitution, eosinophilic tracheobronchitis, and...
Passive smoking by pregnant women and fetal growth.
Ogawa, H, Tominaga, S, Hori, K, Noguchi, K, Kanou, I, Matsubara, M
STUDY OBJECTIVE--The aim was to investigate the effect of passive smoke exposure during pregnancy on fetal growth in the Japanese population. DESIGN--The study comprised a community based interview...
Nonmonocentric urban configurations in a two-dimensional space
A one-dimensional model of nonmonocentric urban land use is extended into a two-dimensional space. Under the assumption of circular symmetry, it is shown that the equilibrium urban configurations in...
De Baets, Johan, Capon, Jan, DE RYCKE, I, De Smet, Herbert, Doutreloigne, Jan, Van Calster, André, ...
De Baets, Johan, Capon, Jan, De Cubber, Ann, De Smet, Herbert, Van Calster, André, Vanfleteren, Jan, ...
De Baets, Johan, Capon, Jan, DE RYCKE, I, De Smet, Herbert, Doutreloigne, Jan, Van Calster, André, ...
Tanaka, N., Ogawa, H., Kinjo, M., Kohga, S., Tanaka, K.
Lewis lung carcinoma cells were implanted in the foot-pads of mice and the effects of the plasminogen-plasmin inhibitor tranexamic acid (t-AMCHA) and of the plasminogen activator urokinase on...
Ido, M., Hayashi, K., Kato, S., Ogawa, H., Komada, Y., Zhau, Y. W., ...
Tumour necrosis factor (TNF)-alpha induces apoptosis in a human acute myeloid leukaemia cell line, Kasumi-1. To examine the role of protein phosphorylation in signal transduction of TNF-alpha-induced...