H. Patel

Publication List Details

Period

1973 - 2009

Number

81

Co-Authors

Effect of maternal diet and body condition on glucose metabolism and skeletal muscle structure in mature adult sheep offspring (2008)

Costello, P.M., Cripps, R.L., Bearpark, N., Rowlerson, A., Hollis, L., Patel, H., ...

Early life nutrition is implicated in the risk of metabolic diseases (e.g. type 2 diabetes) in adulthood. Low birth-weight was associated with defects in the skeletal muscle insulin-signalling...

Extending the desktop workplace by a portable virtual reality system (2006)

Hoffmann, H., Stefani, O., Patel, H.

Users are increasingly recognizing the potential of virtual reality (VR) technology for applications such as data analysis, design review, product development, production planning, marketing,...

Human centred design of 3-D interaction devices to control virtual environments (2006)

Patel, H., Stefani, O., Sharples, S., Hoffmann, H., Karaseitanidis, I., Amditis, A.

It is commonly acknowledged that user needs should drive design, but often technical influences prevail. Currently, there are no standard interaction devices or interfaces used in 3-D environments,...

Practical evaluations of real user company needs for visualization technologies (2006)

Patel, H., Sharples, S., Letourneur, S., Johansson, E., Hoffmann, H., Lorisson, J., ...

The use of visualization technologies by the automotive industry is primarily aimed at increasing competitive advantage. Within the VIEW of the Future project (IST-2000-26089), two automotive...

Heterozygous missense mutations in BSCL2 are associated with distal hereditary motor neuropathy and Silver syndrome (2004)

Windpassinger, C., Auer-Grumbach, M., Irobi, J., Patel, H., Petek, E., Hörl, G., ...

Distal hereditary motor neuropathy (dHMN) or distal spinal muscular atrophy (OMIM #182960) is a heterogeneous group of disorders characterized by an almost exclusive degeneration of motor nerve...

A clinical and genetic study of SPG5A linked autosomal recessive hereditary spastic paraplegia (2003)

Wilkinson, P.A., Crosby, A.H., Turner, C., Patel, H., Wood, N.W., Schapira, A.H., ...

The authors performed a clinical and genetic study of a large consanguineous English family with uncomplicated autosomal recessive hereditary spastic paraplegia (ARHSP). Linkage to the previously...

Mannitol is required for stress tolerance in Aspergillus niger conidiospores (2003)

Ruijter, G.J.G., Bax, M., Patel, H., Flitter, S.J., ...

D-Mannitol is the predominant carbon compound in conidiospores of the filamentous fungus Aspergillus niger and makes up 10 to 15␘f the dry weight. A number of physiological functions have been...

2HAPI: a microarray data analysis system (2003)

Fink, JL, Drewes, S, Patel, H, Welsh, JB, Masys, DR, Corbeil, J, ...

2HAPI (version 2 of High density Array Pattern Interpreter) is a web-based, publicly-available analytical tool designed to aid researchers in microarray data analysis. 2HAPI includes tools for...

Mobilizing grassroots' technological innovations and traditional knowledge, values and institutions: articulating social and ethical capital (2003)

A. K. Gupta, R. Sinha, D. Koradia, R. Patel, M. Parmar, P. Rohit, ...

The Honey Bee Network has helped provide a sort of loose platform to converge creative, but uncoordinated individuals across not only Indian states having varying cultural, linguistic and social...

2HAPI: a microarray data analysis system (2003)

Fink, J. L., Drewes, S., Patel, H., Welsh, J. B., Masys, D. R., Corbeil, J., ...

2HAPI (version 2 of High density Array Pattern Interpreter) is a web-based, publicly-available analytical tool designed to aid researchers in microarray data analysis. 2HAPI includes tools for...

Addressing the social aspects of urban transport through a more effective funding strategy in South Africa (2001)

Patel, H., Freeman, P.N.W., Mitchell, M.F. (Malcolm F.)

This paper was transferred from the original CD ROM created for this conference. The material on the CD ROM was published using Adobe Acrobat technology. The original CD ROM was produced by Document...

Addressing the social aspects of urban transport through a more effective funding strategy in South Africa (2001)

Patel, H., Freeman, P.N.W., Mitchell, M.F. (Malcolm F.)

This paper was transferred from the original CD ROM created for this conference. The material on the CD ROM was published using Adobe Acrobat technology. The original CD ROM was produced by Document...

Partial Scan Design Based on Circuit State Information (1996)

Dong Xiang, Srikanth Venkataraman, W. Kent, Fuchs Janak, H. Patel

State information of a sequential circuit can be used to evaluate the complexity of test generation. The ratio of valid states to all the states of the circuit is an important indicator of test...

Diagnostic Fault Simulation of Sequential Circuits (1992)

Elizabeth M. Rudnick, W. Kent Fuchs, Janak H. Patel, W. Kent, Fuchs Janak, H. Patel

In this work we describe a diagnostic fault simulator for sequential circuits which evaluates the effectiveness of a given test set in distinguishing between faults. Diagnostic fault simulation is...

REFLECTION-ABSORPTION IR SPECTROSCOPY AS AN IN-SITU PROBE OF THE SURFACE CHEMISTRY OF SEMICONDUCTOR GROWTH INTERMEDIATES : THE ADSORPTION OF TRIMETHYLGALLIUM AT GaAs (100) SURFACES AT 300 K (1991)

Patel, H., Pemble, M.

FTIR spectroscopy has been used in reflection-absorption mode to monitor the adsorption of trimethylgallium (TMGa) at GaAs (100) surfaces at 300 K. Intense, positive going transmittance bands are...

SOME INSIGHT INTO THE NATURE OF THE SURFACE CHEMICAL PROCESSES INVOLVED IN THE MOVPE GROWTH OF GaAs FROM ARSINE AND TRIMETHYL- OR TRIETHYL-GALLIUM (1991)

Pemble, M., Buhaenko, D., Patel, H., Stafford, A., Tayor, A.

A now established method of studying reaction pathways in GaAs growth is via the use of surface science and related techniques. This paper sets out to review progress made to date via the use of such...

REFLECTION-ABSORPTION IR SPECTROSCOPY AS AN IN-SITU PROBE OF THE SURFACE CHEMISTRY OF SEMICONDUCTOR GROWTH INTERMEDIATES : THE ADSORPTION OF TRIMETHYLGALLIUM AT GaAs (100) SURFACES AT 300 K (1991)

Patel, H., Pemble, M.

FTIR spectroscopy has been used in reflection-absorption mode to monitor the adsorption of trimethylgallium (TMGa) at GaAs (100) surfaces at 300 K. Intense, positive going transmittance bands are...

SOME INSIGHT INTO THE NATURE OF THE SURFACE CHEMICAL PROCESSES INVOLVED IN THE MOVPE GROWTH OF GaAs FROM ARSINE AND TRIMETHYL- OR TRIETHYL-GALLIUM (1991)

Pemble, M., Buhaenko, D., Patel, H., Stafford, A., Tayor, A.

A now established method of studying reaction pathways in GaAs growth is via the use of surface science and related techniques. This paper sets out to review progress made to date via the use of such...

REFLECTION-ABSORPTION IR SPECTROSCOPY AS AN IN-SITU PROBE OF THE SURFACE CHEMISTRY OF SEMICONDUCTOR GROWTH INTERMEDIATES : THE ADSORPTION OF TRIMETHYLGALLIUM AT GaAs (100) SURFACES AT 300 K (1991)

Patel, H., Pemble, M.

FTIR spectroscopy has been used in reflection-absorption mode to monitor the adsorption of trimethylgallium (TMGa) at GaAs (100) surfaces at 300 K. Intense, positive going transmittance bands are...

SOME INSIGHT INTO THE NATURE OF THE SURFACE CHEMICAL PROCESSES INVOLVED IN THE MOVPE GROWTH OF GaAs FROM ARSINE AND TRIMETHYL- OR TRIETHYL-GALLIUM (1991)

Pemble, M., Buhaenko, D., Patel, H., Stafford, A., Tayor, A.

A now established method of studying reaction pathways in GaAs growth is via the use of surface science and related techniques. This paper sets out to review progress made to date via the use of such...

Three-dimensional structure of the platelet integrin recognition segment of the fibrinogen gamma chain obtained by carrier protein-driven crystallization.

Donahue, J P, Patel, H, Anderson, W F, Hawiger, J

We have developed a method for crystallizing small functional protein segments so that their three-dimensional structure can be determined by x-ray diffraction analysis. This method consists of...

Rapid culture confirmation of herpes simplex virus by a monoclonal antibody-based enzyme immunoassay.

Patel, H, Frenkel, L D, Greenhalgh, M, Howell, R, Patel, S

Rapid confirmation of herpes simplex virus (HSV) is essential in many clinical settings. Viral isolation in cell culture is the standard method for diagnosing HSV infection, with confirmation by...

Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes.

Franklin, R A, Tordai, A, Patel, H, Gardner, A M, Johnson, G L, Gelfand, E W

Stimulation of T cells with antibodies directed towards the T cell receptor complex results in the activation of mitogen-associated protein kinase (MAPK). Two pathways have been described in other...

Comparison of Sentinel and Bactec blood culture systems.

Stevens, M, Patel, H, Walters, A, Burch, K, Jay, A, Dowling, N, ...

AIMS: To evaluate the Sentinel automated blood culture system and to compare its performance with that of Bactec. METHODS: The Sentinel blood culture system was evaluated in three centres. The...

Effects of low-protein diet and starvation on the activity of branched-chain 2-oxo acid dehydrogenase kinase in rat liver and heart.

Espinal, J, Beggs, M, Patel, H, Randle, P J

The activity of branched-chain 2-oxo acid dehydrogenase kinase was 3-fold greater in extracts of heart mitochondria than in extracts of liver mitochondria from rats fed on normal diet. Feeding rats...

Expression of recombinant human serum amyloid A in mammalian cells and demonstration of the region necessary for high-density lipoprotein binding and amyloid fibril formation by site-directed mutagenesis.

Patel, H, Bramall, J, Waters, H, De Beer, M C, Woo, P

Site-directed mutagenesis of the acute-phase human serum amyloid A (SAA1 alpha) protein was used to evaluate the importance of the N-terminal amino acid residues, namely RSFFSFLGEAF The full-length...

The Silver Syndrome Variant of Hereditary Spastic Paraplegia Maps to Chromosome 11q12-q14, with Evidence for Genetic Heterogeneity within This Subtype

Patel, H., Hart, P. E., Warner, T. T., Houlston, R. S., Patton, M. A., Jeffery, S., ...

The hereditary spastic paraplegias (HSPs) are a complex group of neurodegenerative disorders characterized by lower-limb spasticity and weakness. Silver syndrome (SS) is a particularly disabling...

Three-dimensional structure of the platelet integrin recognition segment of the fibrinogen gamma chain obtained by carrier protein-driven crystallization.

Donahue, J P, Patel, H, Anderson, W F, Hawiger, J

We have developed a method for crystallizing small functional protein segments so that their three-dimensional structure can be determined by x-ray diffraction analysis. This method consists of...

Rapid culture confirmation of herpes simplex virus by a monoclonal antibody-based enzyme immunoassay.

Patel, H, Frenkel, L D, Greenhalgh, M, Howell, R, Patel, S

Rapid confirmation of herpes simplex virus (HSV) is essential in many clinical settings. Viral isolation in cell culture is the standard method for diagnosing HSV infection, with confirmation by...

Ligation of the T cell receptor complex results in activation of the Ras/Raf-1/MEK/MAPK cascade in human T lymphocytes.

Franklin, R A, Tordai, A, Patel, H, Gardner, A M, Johnson, G L, Gelfand, E W

Stimulation of T cells with antibodies directed towards the T cell receptor complex results in the activation of mitogen-associated protein kinase (MAPK). Two pathways have been described in other...

Comparison of Sentinel and Bactec blood culture systems.

Stevens, M, Patel, H, Walters, A, Burch, K, Jay, A, Dowling, N, ...

AIMS: To evaluate the Sentinel automated blood culture system and to compare its performance with that of Bactec. METHODS: The Sentinel blood culture system was evaluated in three centres. The...

Effects of low-protein diet and starvation on the activity of branched-chain 2-oxo acid dehydrogenase kinase in rat liver and heart.

Espinal, J, Beggs, M, Patel, H, Randle, P J

The activity of branched-chain 2-oxo acid dehydrogenase kinase was 3-fold greater in extracts of heart mitochondria than in extracts of liver mitochondria from rats fed on normal diet. Feeding rats...

Expression of recombinant human serum amyloid A in mammalian cells and demonstration of the region necessary for high-density lipoprotein binding and amyloid fibril formation by site-directed mutagenesis.

Patel, H, Bramall, J, Waters, H, De Beer, M C, Woo, P

Site-directed mutagenesis of the acute-phase human serum amyloid A (SAA1 alpha) protein was used to evaluate the importance of the N-terminal amino acid residues, namely RSFFSFLGEAF The full-length...

The Silver Syndrome Variant of Hereditary Spastic Paraplegia Maps to Chromosome 11q12-q14, with Evidence for Genetic Heterogeneity within This Subtype

Patel, H., Hart, P. E., Warner, T. T., Houlston, R. S., Patton, M. A., Jeffery, S., ...

The hereditary spastic paraplegias (HSPs) are a complex group of neurodegenerative disorders characterized by lower-limb spasticity and weakness. Silver syndrome (SS) is a particularly disabling...

Prospective analysis of the association of infection with CagA bearing strains of Helicobacter pylori and coronary heart disease

Singh, R K, McMahon, A D, Patel, H, Packard, C J, Rathbone, B J, Samani, N J

Objective: To see whether it was possible to replicate in a prospective study the association recently reported between infection with the more virulent (type 1) cytotoxin associated gene A (CagA)...

Carotenemia in mentally retarded children I. Incidence and etiology

Patel, H., Dunn, H. G., Tischler, B., McBurney, A. Karaa

The incidence and etiology of carotenemia in mentally retarded children were examined. Fasting serum carotenoid and vitamin A levels were measured in 77 profoundly mentally retarded children aged 3...

Spontaneous coronary artery dissection in the postpartum period: association with antiphospholipid antibody

Krishnamurthy, M, Desai, R, Patel, H

Spontaneous coronary artery dissection (SCAD) is an extremely uncommon cause of myocardial infarction, occurring predominantly in women during or after pregnancy. The exact aetiology is unknown. This...

Comparison of human recombinant adenosine A2B receptor function assessed by Fluo-3-AM fluorometry and microphysiometry

Patel, H, Porter, R H P, Palmer, A M, Croucher, M J

The aim of this study was to establish the utility of a fluorometric imaging plate reader (FLIPR) assay to assess human adenosine A2B receptor function by characterizing its receptor pharmacology and...

Office management of minor wounds.

Gouin, S., Patel, H.

OBJECTIVE: To review office interventions for minor wounds not requiring sutures, such as abrasions, bites, and lacerations. QUALITY OF EVIDENCE: Most information on minor wound management comes from...

gamma-Carboxyglutamic acids 36 and 40 do not contribute to human factor IX function.

Gillis, S., Furie, B. C., Furie, B., Patel, H., Huberty, M. C., Switzer, M., ...

The gamma-carboxyglutamic acid (Gla) domains of the vitamin K-dependent blood coagulation proteins contain 10 highly conserved Gla residues within the first 33 residues, but factor IX is unique in...

Where do children go? Comparing the after-hours availability of family physicians and primary care pediatricians in four Canadian cities.

Patel, H., Macarthur, C., Feldman, W.

OBJECTIVE: To describe and compare family physicians' and pediatricians' after-hours availability for pediatric care in four Canadian cities. DESIGN: Cross-sectional telephone survey. SETTING:...

Sources of error in neonatal blood sampling.

Patel, H, Ryan, S W, McLain, B

Significant underestimation of blood electrolyte concentrations may occur if less than 1 ml of blood is withdrawn from an indwelling arterial line before taking the sample for analysis. Compared with...

P131-M Performance Evaluation of a New 6-Channel, Small-Scale Peptide Synthesizer

Campbell, P., Park, J., Patel, H., Racioppo, T., Blais, J., Hensley, B., ...

Protein Technologies has developed a new parallel peptide synthesizer able to perform efficient synthesis at scales from 10 to 350 μmoles. A bench-top model, the Prelude incorporates several...

Boron microlocalization in oral mucosal tissue: implications for boron neutron capture therapy

Morris, G M, Smith, D R, Patel, H, Chandra, S, Morrison, G H, Hopewell, J W, ...

Clinical studies of the treatment of glioma and cutaneous melanoma using boron neutron capture therapy (BNCT) are currently taking place in the USA, Europe and Japan. New BNCT clinical facilities are...