Plasma metanephrines: a novel and cost-effective test for pheochromocytoma (2000)
Eisenhofer,G., Walther,M., Keiser,H.R., Lenders,J.W.M., Friberg,P., Pacak,K.
Pheochromocytomas are rare chromaffin cell tumors that nevertheless must be excluded in large numbers of patients who develop sustained or episodic hypertension as well as in many others with...
Plasma metanephrines in the diagnosis of pheochromocytoma (1996)
Friberg, P., Willemsen, J.J., Jacobs, M.C.G.S., Goldstein, D.S., Keiser, H.R., Lenders, J.W.M.
Plasma metanephrines in the diagnosis of pheochromocytoma (1995)
Eisenhofer, G., Thien, Th., Kloppenborg, P.W.C., Jacobs, M.C.G.S., Friberg, P., Willemsen, J.J., ...
Plasma metanephrines in the diagnosis of pheochromocytoma. (1995)
Eisenhofer, G., Thien, Th., Kloppenborg, P.W.C., Jacobs, M.C.G.S., Friberg, P., Willemsen, J.J., ...
Regulation of postocclusive hyperemia by endogenously synthesized prostaglandins in the dog heart.
Alexander, R W, Kent, K M, Pisano, J J, Keiser, H R, Cooper, T
Experiments were performed to evaluate the role of prostaglandin synthesis in the regulation of coronary blood flow in dog hearts. The left main coronary artery was cannulated and flow measured both...
Goldstein, D S, Horwitz, D, Keiser, H R, Polinsky, R J, Kopin, I J
We infused tracer-labeled l-[3H]-norepinephrine, d-[14C]norepinephrine, and d,l-[3H]-isoproterenol simultaneously into patients with essential hypertension and into normotensive control subjects, in...
Rabbit renomedullary interstitial cells were isolated and grown in tissue culture. These cells synthesize 0.8 ng of prostaglandin E2 (PGE2) per microgram cellular protein per hour in monolayer tissue...
Zusman, R M, Keiser, H R, Handler, J S
Prostaglandin E biosynthesis and its effect on water permeability were investigated in the toad urinary bladder. Arginine vasopressin (1 mU/ml) increased prostaglandin E (PGE) biosynthesis from...
Zusman, R M, Keiser, H R, Handler, J S
Chlorpropamide is known to enhance the water permeability response of the toad urinary bladder to vasopressin and to theophylline. In other studies, we have shown that prostaglandin E synthesis by...
Measurement of regional neuronal removal of norepinephrine in man.
Goldstein, D S, Zimlichman, R, Stull, R, Folio, J, Levinson, P D, Keiser, H R, ...
We describe here and validate an in vivo technique to measure the regional proportionate removal of norepinephrine (NE) by neuronal uptake (Uptake1) in man. The measurement is based on the...
Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans.
Goldstein, D S, Eisenhofer, G, Stull, R, Folio, C J, Keiser, H R, Kopin, I J
We examined plasma levels of the sympathetic neurotransmitter norepinephrine (NE) and its deaminated metabolite dihydroxyphenylglycol (DHPG) during supine rest in healthy human subjects and in...
Surgical management of pheochromocytoma with the use of metyrosine.
Perry, R R, Keiser, H R, Norton, J A, Wall, R T, Robertson, C N, Travis, W, ...
Despite recommended preoperative preparation with alpha-adrenergic blockers, severe hemodynamic instability may occur during operations to resect pheochromocytoma. We combined the alpha-blocker...
Regulation of postocclusive hyperemia by endogenously synthesized prostaglandins in the dog heart.
Alexander, R W, Kent, K M, Pisano, J J, Keiser, H R, Cooper, T
Experiments were performed to evaluate the role of prostaglandin synthesis in the regulation of coronary blood flow in dog hearts. The left main coronary artery was cannulated and flow measured both...
Goldstein, D S, Horwitz, D, Keiser, H R, Polinsky, R J, Kopin, I J
We infused tracer-labeled l-[3H]-norepinephrine, d-[14C]norepinephrine, and d,l-[3H]-isoproterenol simultaneously into patients with essential hypertension and into normotensive control subjects, in...
Rabbit renomedullary interstitial cells were isolated and grown in tissue culture. These cells synthesize 0.8 ng of prostaglandin E2 (PGE2) per microgram cellular protein per hour in monolayer tissue...
Zusman, R M, Keiser, H R, Handler, J S
Prostaglandin E biosynthesis and its effect on water permeability were investigated in the toad urinary bladder. Arginine vasopressin (1 mU/ml) increased prostaglandin E (PGE) biosynthesis from...
Zusman, R M, Keiser, H R, Handler, J S
Chlorpropamide is known to enhance the water permeability response of the toad urinary bladder to vasopressin and to theophylline. In other studies, we have shown that prostaglandin E synthesis by...
Measurement of regional neuronal removal of norepinephrine in man.
Goldstein, D S, Zimlichman, R, Stull, R, Folio, J, Levinson, P D, Keiser, H R, ...
We describe here and validate an in vivo technique to measure the regional proportionate removal of norepinephrine (NE) by neuronal uptake (Uptake1) in man. The measurement is based on the...
Plasma dihydroxyphenylglycol and the intraneuronal disposition of norepinephrine in humans.
Goldstein, D S, Eisenhofer, G, Stull, R, Folio, C J, Keiser, H R, Kopin, I J
We examined plasma levels of the sympathetic neurotransmitter norepinephrine (NE) and its deaminated metabolite dihydroxyphenylglycol (DHPG) during supine rest in healthy human subjects and in...
Surgical management of pheochromocytoma with the use of metyrosine.
Perry, R R, Keiser, H R, Norton, J A, Wall, R T, Robertson, C N, Travis, W, ...
Despite recommended preoperative preparation with alpha-adrenergic blockers, severe hemodynamic instability may occur during operations to resect pheochromocytoma. We combined the alpha-blocker...
Hydrolysis of iodine labelled urodilatin and ANP by recombinant neutral endopeptidase EC. 3.4.24.11.
Abassi, Z A, Golomb, E, Agbaria, R, Roller, P P, Tate, J, Keiser, H R
1. Urodilatin is a 32 amino-acid peptide of similar sequence to atrial natriuretic peptide (ANP), with four additional amino-acids at the N-terminus. Although ANP and urodilatin bind to the same...
Metabolism of endothelin-1 and big endothelin-1 by recombinant neutral endopeptidase EC.3.4.24.11.
Abassi, Z. A., Golomb, E., Bridenbaugh, R., Keiser, H. R.
1. Inhibitors of neutral endopeptidase EC.3.4.24.11 (NEP) have been shown to attenuate the hypertensive effect of big-endothelin-1 (BET-1) in rats. To determine whether NEP converts BET-1 to...