H. Sakai

Publication List Details

Period

1967 - 2009

Number

217

Co-Authors

$^{235}$U nuclear relaxation rates in an itinerant antiferromagnet USb$_2$ (2009)

Curro, N. J., Sakai, H., Bauer, E. D., Cooley, J. C., Smith, J. L.

$^{235}$U nuclear spin-lattice ($T_1^{-1}$) and spin-spin ($T_2^{-1}$) relaxation rates in the itinerant antiferromagnet USb$_2$ are reported as a function of temperature in zero field. The heating...

Spin-isospin selectivity in three-nucleon forces (2009)

Mardanpour, H., Amir-Ahmadi, H. R., Benard, R., Biegun, A., Eslami-Kalantari, M., Joulaeizadeh, L., ...

Precision data are presented for the break-up reaction, $^2{\rm H}(\vec p,pp)n$, within the framework of nuclear-force studies. The experiment was carried out at KVI using a polarized-proton beam of...

Spectroscopy of 13B via the 13C(t,3He) reaction at 115 AMeV (2009)

Guess, C. J., Zegers, R. G. T., Brown, B. A., Austin, Sam M., Bazin, D., Caesar, C., ...

Gamow-Teller and dipole transitions to final states in 13B were studied via the 13C(t,3He) reaction at Et = 115 AMeV. Besides the strong Gamow-Teller transition to the 13B ground state, a weaker...

Superconductivity and the Effects of Pressure and Structure in Single Crystalline SrNi$_2$P$_2$ (2009)

Ronning, F., Bauer, E. D., Park, T., Sakai, H., Thompson, J. D.

Heat capacity, magnetic susceptibility, NMR, and resistivity of SrNi2P2 single crystals are presented, illustrating a purely structural transition at 325 K with no magnetism. Bulk superconductivity...

Neutrino-less Double Beta Decay of 48Ca studied by CaF2(Eu) Scintillators (2008)

Umehara, S., Kishimoto, T., Ogawa, I., Hazama, R., Miyawaki, H., Yoshida, S., ...

We searched for the neutrino-less double beta decay(0nbb) of 48Ca by using CaF2(Eu) scintillators. Analysis of their pulse shapes was effective to reduce backgrounds. No events are observed in the...

Dopant-dependent impact of Mn-site doping on the critical-state manganites: R0.6Sr0.4MnO3 (R=La, Nd, Sm, and Gd) (2008)

Sakai, H., Ito, K., Nishiyama, T., Yu, X. Z., Matsui, Y., Miyasaka, S., ...

Versatile features of impurity doping effects on perovskite manganites, $R_{0.6}$Sr$_{0.4}$MnO$_{3}$, have been investigated with varying the doing species as well as the $R$-dependent one-electron...

Pacific Symposium on Biocomputing 9:54-65(2004) EXTENSIVE SEARCH FOR DISCRIMINATIVE FEATURES OF ALTERNATIVE SPLICING (2008)

H. Sakai, O. Maruyama, H. Sakai A

Alternative pre-mRNA splicing events can be classified into various types, including cassette, mutually exclusive, alternative 3 ’ splice site, alternative 5 ’ splice site, retained intron. The...

Current-induced persistent magnetization in a relaxorlike manganite (2008)

Sakai, H., Tokura, Y.

A single crystal of 7% Fe-doped (La$_{0.7}$Pr$_{0.3}$)$_{0.65}$Ca$_{0.35}$MnO$_3$ shows up as a typical relaxor ferromagnet, where ferromagnetic metallic and charge-orbital-ordered insulating...

Extensive Search for Discriminative Features of Alternative Splicing (2008)

H. Sakai, O. Maruyama

Alternative pre-mRNA splicing events can be classified into various types, including cassette, mutually exclusive, alternative 3' splice site, alternative 5' splice site, retained intron....

Changes in C3/C4 vegetation in the continental interior of the Central Himalayas associated with monsoonal paleoclimatic changes during the last 600 kyr (2008)

Mampuku, M., Yamanaka, T., Uchida, M., Fujii, R., Maki, T., Sakai, H.

A continuous lacustrine sediment core obtained from the Kathmandu Valley in the Central Himalayas revealed that cyclical changes in C3/C4 vegetation corresponded to global glacial-interglacial cycles...

Changes in C3/C4 vegetation in the continental interior of the Central Himalayas associated with monsoonal paleoclimatic changes during the last 600 kyr (2008)

Mampuku, M., Yamanaka, T., Uchida, M., Fujii, R., Maki, T., Sakai, H.

A continuous lacustrine sediment core obtained from the Kathmandu Valley in the Central Himalayas revealed that cyclical changes in C3/C4 vegetation corresponded to global glacial-interglacial cycles...

Changes in C3/C4 vegetation in the continental interior of the Central Himalayas associated with monsoonal paleoclimatic changes during the last 600 kyr (2008)

M. Mampuku, T. Yamanaka, M. Uchida, R. Fujii, T. Maki, H. Sakai

A continuous lacustrine sediment core obtained from the Kathmandu Valley in the Central Himalayas revealed that cyclical changes in C3/C4 vegetation corresponded to global glacial-interglacial cycles...

Fe-doping-induced evolution of charge-orbital ordering in a bicritical-state manganite (2007)

Sakai, H., Ito, K., Kumai, R., Tokura, Y.

Impurity effects on the stability of a ferromagnetic metallic state in a bicritical-state manganite, (La0.7Pr0.3)0.65Ca0.35MnO3, on the verge of metal-insulator transition have been investigated by...

Analyzing powers Ayy, Axx, Axz and Ay in the dd->3Hen reaction at 270 MeV (2007)

Janek, M., Saito, T., Ladygin, V. P., Uesaka, T., Hatano, M., Isupov, A. Yu., ...

The data on the tensor Ayy, Axx, Axz and vector Ay analyzing powers in the dd->3Hen obtained at Td= 270 MeV in the angular range 0 - 110 degrees in the c.m. are presented. The observed negative sign...

Compensation of the Crossing Angle with Crab Cavities at KEKB (2007)

Abe, T., Akai, K., Akemoto, M., Akiyama, A., Arinaga, M., Ebihara, K., ...

Crab cavities have been installed in the KEKB B--Factory rings to compensate the crossing angle at the collision point and thus increase luminosity. The beam operation with crab crossing has been...

Charge Exchange Spin-Dipole Excitations of 90Zr and 208Pb and Neutron Matter Equation of State (2007)

Sagawa, H., Yoshida, Satoshi, Zhou, Xian-Rong, Yako, K., Sakai, H.

Charge exchange spin-dipole (SD) excitations of $^{90}$Zr and $^{208}$Pb are studied by using a Skyrme Hartree-Fock(HF) + Random Phase approximation (RPA). The calculated spin-dipole strength...

Cultured articular chondrocytes sheets for partial thickness cartilage defects utilizing temperature-responsive culture dishes (2007)

N Kaneshiro, M Sato, M Ishihara, G Mitani, H Sakai, T Kikuchi, ...

The extracellular matrix (ECM) of articular cartilage has several functions that are unique to joints. Although a technique for transplanting cultured chondrocytes has already been introduced, it is...

Changes in C3/C4 vegetation in the continental interior of the Central Himalayas associated with monsoonal paleoclimatic changes during the last 600 kyr (2007)

Mampuku, M., Yamanaka, T., Uchida, M., Fujii, R., Maki, T., Sakai, H.

A continuous lacustrine sediment core obtained from the Kathmandu Valley in the Central Himalayas revealed that cyclical changes in C3/C4 vegetation corresponded to global glacial-interglacial cycles...

Changes in C3/C4 vegetation in the continental interior of the Central Himalayas associated with monsoonal paleoclimatic changes during the last 600 kyr (2007)

Mampuku, M., Yamanaka, T., Uchida, M., Fujii, R., Maki, T., Sakai, H.

A continuous lacustrine sediment core obtained from the Kathmandu Valley in the Central Himalayas revealed that cyclical changes in C3/C4 vegetation corresponded to global glacial-interglacial cycles...

Changes in C3/C4 vegetation in the continental interior of the Central Himalayas associated with monsoonal paleoclimatic changes during the last 600 kyr (2007)

M. Mampuku, T. Yamanaka, M. Uchida, R. Fujii, T. Maki, H. Sakai

A continuous lacustrine sediment core obtained from the Kathmandu Valley in the Central Himalayas revealed that cyclical changes in C3/C4 vegetation corresponded to global glacial-interglacial cycles...

Precision measurement of vector and tensor analyzing powers in elastic deuteron-proton scattering (2006)

Mardanpour, H., Amir-Ahmadi, H. R., Deltuva, A., Itoh, K., Kalantar-Nayestanaki, N., Kawabata, T., ...

High precision vector and tensor analyzing powers of elastic deuteron-proton d+p scattering have been measured at intermediate energies to investigate effects of three-nucleon forces (3NF). Angular...

Neutron Skin Thickness of 90Zr Determined By Charge Exchange Reactions (2006)

Yako, K., Sagawa, H., Sakai, H.

Charge exchange spin-dipole (SD) excitations of 90Zr are studied by the 90Zr(p,n) and 90Zr(n,p) reactions at 300 MeV. A multipole decomposition technique is employed to obtain the SD strength...

Spin gap in Tl2Ru2O7 and the possible formation of Haldane chains in three-dimensional crystals (2006)

Lee, S., Adroja, D.T., Khomskii, D., Streltsov, S., McEwen, K.A., ...

Dimensionality is one of the most important parameters of physical phenomena. Only two things determine the universality class of a phase transition: the dimensionality of a given system and the...

Magnetic state dynamics in itinerant paramagnet UM3B2 (M= Co, Ir) probed by 11B NMR (2006)

Fujimoto, T., Sakai, H., Tokunaga, Y., Kambe, S., Walstedt, R. E., Ikeda, S., ...

We have carried out the $^{11}$B NMR measurement on the itinerant paramagnetic systems U$M_{3}$B$_{2}$ ($M =$ Co, Ir) to investigate the low-dimensional characteristics of the $5f$-electrons due to...

Image contrast analysis of STM images of self-assembled dioctadecyl chalcogenides on graphite at the liquid-solid interface (2005)

L-i, D, Nishio, S, Sakai, H, Ohuchi, A

The structures of self-assembled monolayers of dioctadecyl selenide (CH3(CH2)(17))(2)Se and dioctadecyl telluride (CH3(CH2)(17))(2)Te, as well as dioctadecyl ether (CH3(CH2)(17))(2)O and dioctadecyl...

Resolving the Discrepancy of 135 MeV pd Elastic Scattering Cross Sections and Relativistic Effects (2005)

Sekiguchi, K., Sakai, H., Witała, H., Gloeckle, W., Golak, J., Hatanaka, K., ...

Three precise measurements for elastic pd scattering at 135 MeV/A have been performed with the three different experimental setups. The cross sections are described well by the theoretical...

Anisotropic superconducting gap in transuranium superconductor PuRhGa$_{5}$: Ga NQR study on a single crystal (2005)

Sakai, H., Tokunaga, Y., Fujimoto, T., Kambe, S., Walstedt, R. E., Yasuoka, H., ...

^{69,71}Ga NMR/NQR studies have been performed on a single crystal of the transuranium superconductor PuRhGa_{5} with Tc ~ 9 K. We have observed a ^{69}Ga NQR line at ~29.15 MHz, and assigned it to...

Performance of the neutron polarimeter NPOL3 for high resolution measurements (2005)

Wakasa, T., Hagihara, Y., Sasano, M., Asaji, S., Fujita, K., Hatanaka, K., ...

We describe the neutron polarimeter NPOL3 for the measurement of polarization transfer observables $D_{ij}$ with a typical high resolution of $\sim$300 keV at $T_n$ $\simeq$ 200 MeV. The NPOL3 system...

Unified Analysis of Spin Isospin Responses of Nuclei (2004)

Wakasa, T., Ichimura, M., Sakai, H.

We investigated the Gamow-Teller (GT) strength distribution, especially the quenching with respect to the GT sum rule, and the enhancement of the pionic responses in the quasielasic scattering...

Determination of the Gamow-Teller Quenching Factor from Charge Exchange Reactions on 90Zr (2004)

Yako, K., Sakai, H., Greenfield, M. B., Hatanaka, K., Hatano, M., Kamiya, J., ...

Double differential cross sections between 0-12 degrees were measured for the 90Zr(n,p) reaction at 293 MeV over a wide excitation energy range of 0-70 MeV. A multipole decomposition technique was...

Measurement of the tensor analyzing power T20 in the dd->^3Hen and dd->^3Hp at intermediate energies and at zero degree (2004)

Ladygin, V. P., Uesaka, T., Saito, T., Hatano, M., Isupov, A. Yu., Kato, H., ...

The data on the tensor analyzing power T20 in the dd->^3Hen and dd-> ^3Hp reactions at 140, 200 and 270 MeV of the deuteron kinetic energy and at zero degree obtained at RIKEN Accelerator Research...

Polarization Transfer Measurement for $^1H(\vec{d},\vec{p})^2 H$ Elastic Scattering at 135 MeV/u and Three Nucleon Force Effects (2004)

Sekiguchi, K., Sakai, H., Witała, H., Ermisch, K., Glöckle, W., Golak, J., ...

The deuteron to proton polarization transfer coefficients for the $d$--$p$ elastic scattering were precisely measured with an incoming deuteron energy of 135 MeV/u at the RIKEN Accelerator Research...

Sore throat and hoarseness after total intravenous anaesthesia (2004)

Maruyama, K., Sakai, H., Miyazawa, H., Toda, N., Iinuma, Y., Mochizuki, N., ...

Background. Sore throat and hoarseness are common complications, but these have not been studied after total i.v. anaesthesia. Methods. We prospectively studied 418 surgical patients, aged 15–92...

Sore throat and hoarseness after total intravenous anaesthesia (2004)

Maruyama, K., Sakai, H., Miyazawa, H., Toda, N., Iinuma, Y., Mochizuki, N., ...

Background. Sore throat and hoarseness are common complications, but these have not been studied after total i.v. anaesthesia. Methods. We prospectively studied 418 surgical patients, aged 15-92 yr,...

Sore throat and hoarseness after total intravenous anaesthesia (2004)

Maruyama, K., Sakai, H., Miyazawa, H., Toda, N., Iinuma, Y., Mochizuki, N., ...

Background. Sore throat and hoarseness are common complications, but these have not been studied after total i.v. anaesthesia. Methods. We prospectively studied 418 surgical patients, aged 15-92 yr,...

Achievement of ultra-low emittance beam in the ATF damping ring (2003)

Honda, Y, Anderson, S, Araki, S, Bane, Karl Leopold Freitag, Brachmann, A, Frisch, J, ...

We report on the smallest vertical emittance achieved in single-bunch-mode operation of the ATF. The emittances were measured with a laser-wire beam-profile monitor installed in the damping ring. The...

High-resolution Photoemission Study of Cd2Re2O7 (2002)

Irizawa, A., Higashiya, A., Kasai, S., Sasabayashi, T., Shigemoto, A., Sekiyama, A., ...

High-resolution bulk-sensitive photoemission has been measured for pyrochlore oxide Cd2Re2O7. Temperature variations of the spectral shapes between 20 and 250 K are obviously observed for the Re 4f...

Three-body dN interaction in the analysis of the 12C(pol_d,d') reaction at 270 MeV (2002)

Satou, Y., Ishida, S., Sakai, H., Okamura, H., Sakamoto, N., Otsu, H., ...

We have measured the cross sections and analyzing powers Ay and Ayy for the elastic and inelastic scattering of deuterons from the 0+(g.s.), 2+(4.44 MeV), 3-(9.64 MeV), 1+(12.71 MeV), and 2-(18.3...

Quenching of neutron E2 effective charge in neutron-rich nuclei and the ground-state spin-parity of C-17 (2002)

Asahi, K, Ueno, H, Sakai, H, Miyoshi, H, Kameda, D, ...

The electric quadrupole moment of B-17 and the g-factor of C-17 were measured by using the fragmentation-induced nuclear polarization technique combined with the beta-NMR method. The experimental...

Measurement of Single and Double Spin-Flip Probabilities in Inelastic Deuteron Scattering on 12C at 270 MeV (2001)

Satou, Y., Ishida, S., Sakai, H., Okamura, H., Otsu, H., Sakamoto, N., ...

The deuteron single and double spin-flip probabilities, S1 and S2, have been measured for the 12C(pol{d},pol{d}') reaction at Ed = 270 MeV for an excitation energy range between 4 and 24 MeV and a...

Superconductivity in a pyrochlore oxide Cd2Re2O7 (2001)

Sakai, H., Yoshimura, K., Ohno, H., Kato, H., Kambe, S., Walstedt, R. E., ...

We make the first report that a metallic pyrochlore oxide \Cd2Re2O7, exhibits type II superconductivity at 1.1 K. The pyrochlore oxide is known to be a geometrical frustrated system, which includes...

Reaction mechanism and characteristics of T_{20} in d + ^3He backward elastic scattering at intermediate energies (1999)

Tanifuji, M., Ishikawa, S., Iseri, Y., Uesaka, T., Sakamoto, N., Satou, Y., ...

For backward elastic scattering of deuterons by ^3He, cross sections \sigma and tensor analyzing power T_{20} are measured at E_d=140-270 MeV. The data are analyzed by the PWIA and by the general...

The Landau-Migdal Parameters, g'_NN and g'_N\Delta and Pion Condensations (1999)

Suzuki, T., Sakai, H., Tatsumi, T.

The Landau-Migdal parameters for nucleon-nucleon (g'_NN) and nucleon-\Delta (g'_N\Delta) couplings are estimated from recent experimental data on the giant Gamow-Teller state of 90Nb. The observed...

Pulse Shape Recognition for CdZnTe Semiconductor Detector by using Multi-Shaping Amplifiers Method with Neural Network Algorithm (1998)

Sakai, H., Uritani, A., Mori, C., Iguchi, T.

A new pulse shape recognition method with multi-shaping amplifiers, combined with a neural network algorithm, has been developed, where four pulse heights are sampled from one signal pulse through...

Endoscopic Diagnosis and Treatment of a Case of Respiratory Papillomatosis (1997)

T. Hirano, C. Konaka, S. Okada, H. Shibanuma, E. Shimizu, T. Okunaka, ...

Respiratory papilloma is a rare lesion that arises in the larynx, trachea and bronchus. We describe a patient with laryngeal papilloma that spread to the trachea and which was effectively treated by...

The Effect of EDTA on Incorporation of [3H] Methionine into Two-Cell Mouse Embryos (1996)

Tsujii, H, Sakai, H, Takagi, Y

To investigate the effect of EDTA on the in vitro development of mouse embryos from 1-cell to blastocyst, the embryos were cultured in M 16 and M 16 plus EDTA. The incorporation of[3H]methionine...

Bilinear structure and Schlesinger transforms of the $q$-P$_{\rm III}$ and $q$-P$_{\rm VI}$ equations (1996)

Jimbo, M., Sakai, H., Ramani, A., Grammaticos, B.

We show that the recently derived ($q$-) discrete form of the Painlev\'e VI equation can be related to the discrete P$_{\rm III}$, in particular if one uses the full freedom in the implementation of...

Video-Assisted Thoracoscopic Surgery in Patients With Clinically Resectable Lung Tumors (1996)

H. Sakai, P. J. Borgstein, M. A. Cuesta, S. Meijer, G. Sutedja, ...

To investigate the feasibility of thoracoscopic resection, a pilot study was performed in patients with clinically resectable lung tumors. In 40 patients, Video-assisted thoracic surgery (VATS) was...

Transmission of Medium Energy Neutrons Through Concrete Shields (1991)

Shin, K., Ishii, Y., Uwamino, Y., Sakai, H., Numata, S.

Transmission measurements of medium energy neutrons through concrete shields are described. Neutrons which were produced by the bombardment of 75 MeV protons on a thick Cu target, were collimated to...

ANALYZING POWER OF NEUTRON CONTINUUM SPECTRA FOR THE 93Nb([MATH], nX) REACTION AT 65 MeV (1984)

Sakai, H., Hatanaka, K., Matsuoka, N., Motobayashi, T., Saito, T ., Shibata, T., ...

Analyzing power of neutron continuum spectra for the 93Nb([MATH], nX) reaction at 65 MeV has been measured for the wide angular range θn = 20° -130°. The analyzing powers are positive and...

ANALYZING POWER OF NEUTRON CONTINUUM SPECTRA FOR THE 93Nb([MATH], nX) REACTION AT 65 MeV (1984)

Sakai, H., Hatanaka, K., Matsuoka, N., Motobayashi, T., Saito, T ., Shibata, T., ...

Analyzing power of neutron continuum spectra for the 93Nb([MATH], nX) reaction at 65 MeV has been measured for the wide angular range θn = 20° -130°. The analyzing powers are positive and...

ANALYZING POWER OF NEUTRON CONTINUUM SPECTRA FOR THE 93Nb([MATH], nX) REACTION AT 65 MeV (1984)

Sakai, H., Hatanaka, K., Matsuoka, N., Motobayashi, T., Saito, T ., Shibata, T., ...

Analyzing power of neutron continuum spectra for the 93Nb([MATH], nX) reaction at 65 MeV has been measured for the wide angular range θn = 20° -130°. The analyzing powers are positive and...

129I MÖSSBAUER STUDY OF CHARGE TRANSFER COMPLEXES OF IODINE IN THE FROZEN SOLUTION (1979)

Sakai, H., Maeda, Y., Ichiba, S., Negita, H.

The Mössbauer effect of 129I was used to investigate the charge transfer complexes of triethylamine-iodine and pyridine-iodine in the carbon disulfide frozen solution at 16 K. The Mössbauer spectra...

57Co MÖSSBAUER EMMISSION SPECTROSCOPY IN COBALT-OCTAETHYLPORPHYRIN (1979)

Sakai, H., Maeda, Y., Ogoshi, H., Sugimoto, H., Yoshida, Z.

57Fe Mössbauer emission spectra of 57Co(II)OEP and 57Co(III)OEP. Br.Py complexes (OEP= octaethylporphyrin) have been measured at various temperatures versus K4Fe(CN)6. 3H2O as absorber. The spectra...

A STUDY OF LOCAL ATOMIC AND ELECTRONIC STRUCTURES OF LIQUID-QUENCHED La-Au ALLOYS BY 197Au AND 57Fe SPECTROSCOPY (1979)

Nanao, S., Sugiura, J., Ino, H., Maeda, Y., Sakai, H.

Mössbauer spectra of 197 and 57 Fe nuclei in the liquid-quenched La-Au alloys were measured, with which the atomic structures of the amorphous phase and the supersaturated β-La phase were...

MÖSSBAUER STUDIES OF JAPANESE ANCIENT POTTERY (1979)

Maeda, Y., Sakai, H., Onoyama, S., Yoshida, E.

Mössbauer spectroscopy has been used to characterize Japanese ancient pottery from Haji and Sue wars. The firing conditions such as temperature and atmosphere were deduced from a model firing...

A STUDY OF LOCAL ATOMIC AND ELECTRONIC STRUCTURES OF LIQUID-QUENCHED La-Au ALLOYS BY 197Au AND 57Fe SPECTROSCOPY (1979)

Nanao, S., Sugiura, J., Ino, H., Maeda, Y., Sakai, H.

Mössbauer spectra of 197 and 57 Fe nuclei in the liquid-quenched La-Au alloys were measured, with which the atomic structures of the amorphous phase and the supersaturated β-La phase were...

MÖSSBAUER STUDIES OF JAPANESE ANCIENT POTTERY (1979)

Maeda, Y., Sakai, H., Onoyama, S., Yoshida, E.

Mössbauer spectroscopy has been used to characterize Japanese ancient pottery from Haji and Sue wars. The firing conditions such as temperature and atmosphere were deduced from a model firing...

129I MÖSSBAUER STUDY OF CHARGE TRANSFER COMPLEXES OF IODINE IN THE FROZEN SOLUTION (1979)

Sakai, H., Maeda, Y., Ichiba, S., Negita, H.

The Mössbauer effect of 129I was used to investigate the charge transfer complexes of triethylamine-iodine and pyridine-iodine in the carbon disulfide frozen solution at 16 K. The Mössbauer spectra...

57Co MÖSSBAUER EMMISSION SPECTROSCOPY IN COBALT-OCTAETHYLPORPHYRIN (1979)

Sakai, H., Maeda, Y., Ogoshi, H., Sugimoto, H., Yoshida, Z.

57Fe Mössbauer emission spectra of 57Co(II)OEP and 57Co(III)OEP. Br.Py complexes (OEP= octaethylporphyrin) have been measured at various temperatures versus K4Fe(CN)6. 3H2O as absorber. The spectra...

129I MÖSSBAUER STUDY OF CHARGE TRANSFER COMPLEXES OF IODINE IN THE FROZEN SOLUTION (1979)

Sakai, H., Maeda, Y., Ichiba, S., Negita, H.

The Mössbauer effect of 129I was used to investigate the charge transfer complexes of triethylamine-iodine and pyridine-iodine in the carbon disulfide frozen solution at 16 K. The Mössbauer spectra...

57Co MÖSSBAUER EMMISSION SPECTROSCOPY IN COBALT-OCTAETHYLPORPHYRIN (1979)

Sakai, H., Maeda, Y., Ogoshi, H., Sugimoto, H., Yoshida, Z.

57Fe Mössbauer emission spectra of 57Co(II)OEP and 57Co(III)OEP. Br.Py complexes (OEP= octaethylporphyrin) have been measured at various temperatures versus K4Fe(CN)6. 3H2O as absorber. The spectra...

A STUDY OF LOCAL ATOMIC AND ELECTRONIC STRUCTURES OF LIQUID-QUENCHED La-Au ALLOYS BY 197Au AND 57Fe SPECTROSCOPY (1979)

Nanao, S., Sugiura, J., Ino, H., Maeda, Y., Sakai, H.

Mössbauer spectra of 197 and 57 Fe nuclei in the liquid-quenched La-Au alloys were measured, with which the atomic structures of the amorphous phase and the supersaturated β-La phase were...

MÖSSBAUER STUDIES OF JAPANESE ANCIENT POTTERY (1979)

Maeda, Y., Sakai, H., Onoyama, S., Yoshida, E.

Mössbauer spectroscopy has been used to characterize Japanese ancient pottery from Haji and Sue wars. The firing conditions such as temperature and atmosphere were deduced from a model firing...

Fe57 POLARIMETRY BASED ON QUADRUPOLE INTERACTION (1976)

Gonser, U., Sakai, H., Keune, W.

A quadrupole Fe57 polarimeter consisting of single crystals of LiNbO3 : CO57 as source (polarizer) and of FeCO3 (siderite) as absorber (analyzer) is described. The quadrupole interactions of the two...

Fe57 POLARIMETRY BASED ON QUADRUPOLE INTERACTION (1976)

Gonser, U., Sakai, H., Keune, W.

A quadrupole Fe57 polarimeter consisting of single crystals of LiNbO3 : CO57 as source (polarizer) and of FeCO3 (siderite) as absorber (analyzer) is described. The quadrupole interactions of the two...

Fe57 POLARIMETRY BASED ON QUADRUPOLE INTERACTION (1976)

Gonser, U., Sakai, H., Keune, W.

A quadrupole Fe57 polarimeter consisting of single crystals of LiNbO3 : CO57 as source (polarizer) and of FeCO3 (siderite) as absorber (analyzer) is described. The quadrupole interactions of the two...

Effect of Heat Treatment of Anodic Oxide Films on Aluminium on Their Photoluminescent Properties (1976)

S. Tajima, K. Shimizu, N. Baba, H. Sakai

Heating of anodic oxide films on aluminium produced irreversible changes in their photoluminescent properties. In the case of oxalic acid films, for instance, PL intensity increased exponentially...

Heterogeneity of the DNA preparation from light-anaerobically grown Rhodopseudomonas spheroides cells as revealed by methylated albumin kieselguhr column chromatography (1975)

Higuchi, M., Sakai, H.

Biochemical properties of DNA preparations obtained from light-anaerobically growth R. spheroides cells and from dark-aerobically grown cells were examined comparatively using methylated albumin...

IDEALAB FOURIER TRANSFORM ANALOG COMPUTER (1967)

Pritchard, J., Bullard, A., Sakai, H., Vanasse, G.

The IFTAC is a special purpose analog computer designed to take the direct Fourier transform of a recorded function C(t). The system uses a recorded time base generated by a monochromatic source in...

MÖBIUS BAND INTERFEROMETER AND ITS APPLICATION TO FOURIER SPECTROSCOPY (1967)

Pritchard, J., Sakai, H., Steel, W., Vanasse, G.

In Fourier spectroscopy a tilting of the wavefront while the interferogram is being recorded gives rise to false structure in the computed spectrum. It is desirable to automatically tilt compensate...

IDEALAB FOURIER TRANSFORM ANALOG COMPUTER (1967)

Pritchard, J., Bullard, A., Sakai, H., Vanasse, G.

The IFTAC is a special purpose analog computer designed to take the direct Fourier transform of a recorded function C(t). The system uses a recorded time base generated by a monochromatic source in...

MÖBIUS BAND INTERFEROMETER AND ITS APPLICATION TO FOURIER SPECTROSCOPY (1967)

Pritchard, J., Sakai, H., Steel, W., Vanasse, G.

In Fourier spectroscopy a tilting of the wavefront while the interferogram is being recorded gives rise to false structure in the computed spectrum. It is desirable to automatically tilt compensate...

IDEALAB FOURIER TRANSFORM ANALOG COMPUTER (1967)

Pritchard, J., Bullard, A., Sakai, H., Vanasse, G.

The IFTAC is a special purpose analog computer designed to take the direct Fourier transform of a recorded function C(t). The system uses a recorded time base generated by a monochromatic source in...

MÖBIUS BAND INTERFEROMETER AND ITS APPLICATION TO FOURIER SPECTROSCOPY (1967)

Pritchard, J., Sakai, H., Steel, W., Vanasse, G.

In Fourier spectroscopy a tilting of the wavefront while the interferogram is being recorded gives rise to false structure in the computed spectrum. It is desirable to automatically tilt compensate...

Nascent polypeptide-associated complex protein prevents mistargeting of nascent chains to the endoplasmic reticulum.

Lauring, B, Sakai, H, Kreibich, G, Wiedmann, M

We show that, after removal of the nascent polypeptide-associated complex (NAC) from ribosome-associated nascent chains, ribosomes synthesizing proteins lacking signal peptides are efficiently...

Cloning and sequence analysis of the rat augmenter of liver regeneration (ALR) gene: expression of biologically active recombinant ALR and demonstration of tissue distribution.

Hagiya, M, Francavilla, A, Polimeno, L, Ihara, I, Sakai, H, Seki, T, ...

A full-length cDNA clone encoding a purified augmenter of liver regeneration (ALR) factor prepared from the cytosol of weanling rat livers was isolated. The 1.2-kb cDNA included a 299-bp 5'...

Functional division and reconstruction of a plasmid replication origin: molecular dissection of the oriV of the broad-host-range plasmid RSF1010.

Honda, Y, Sakai, H, Hiasa, H, Tanaka, K, Komano, T, Bagdasarian, M

Two single-stranded DNA initiation signals (designated ssi) present in the origin of vegetative DNA replication (oriV) of the broad-host-range plasmid RSF1010 are essential for the priming of...

EIN4 and ERS2 are members of the putative ethylene receptor gene family in Arabidopsis.

Hua, J, Sakai, H, Nourizadeh, S, Chen, Q G, Bleecker, A B, Ecker, J R, ...

The Arabidopsis ethylene receptor gene ETR1 and two related genes, ERS1 and ETR2, were identified previously. These three genes encode proteins homologous to the two-component regulators that are...

Functional features of an ssi signal of plasmid pGKV21 in Escherichia coli.

Jeong, J Y, Yoon, G M, Seo, H S, Cho, M J, Sakai, H, Komano, T, ...

A single-strand initiation (ssi) signal was detected on the Lactococcus lactis plasmid pGKV21 containing the replicon of pWV01 by its ability to complement the poor growth of an M13 phage derivative...

Effects of translation initiation factor eIF-5A on the functioning of human T-cell leukemia virus type I Rex and human immunodeficiency virus Rev inhibited trans dominantly by a Rex mutant deficient in RNA binding.

Katahira, J, Ishizaki, T, Sakai, H, Adachi, A, Yamamoto, K, Shida, H

The viral transactivator proteins Rex and Rev are necessary for the expression of structural proteins of human T-cell leukemia virus type I and human immunodeficiency virus type 1, respectively....

Targeted mutagenesis of the human papillomavirus type 16 E2 transactivation domain reveals separable transcriptional activation and DNA replication functions.

Sakai, H, Yasugi, T, Benson, J D, Dowhanick, J J, Howley, P M

The E2 gene products of papillomavirus play key roles in viral replication, both as regulators of viral transcription and as auxiliary factors that act with E1 in viral DNA replication. We have...

Mapping and characterization of the interaction domains of human papillomavirus type 16 E1 and E2 proteins.

Yasugi, T, Benson, J D, Sakai, H, Vidal, M, Howley, P M

The papillomavirus E1 and E2 proteins are both necessary and sufficient in vivo for efficient origin-dependent viral DNA replication. The ability of E1 and E2 to complex with each other appears to be...

Two classes of human papillomavirus type 16 E1 mutants suggest pleiotropic conformational constraints affecting E1 multimerization, E2 interaction, and interaction with cellular proteins.

Yasugi, T, Vidal, M, Sakai, H, Howley, P M, Benson, J D

Random mutagenesis of human papillomavirus type 16 (HPV16) E1 was used to generate E1 missense mutants defective for interaction with either hUBC9 or 16E1-BP, two cDNAs encoding proteins that have...

Transcriptional regulation of Bacillus thuringiensis subsp. israelensis mosquito larvicidal crystal protein gene cryIVA.

Yoshisue, H, Fukada, T, Yoshida, K, Sen, K, Kurosawa, S, Sakai, H, ...

The cryIVA gene encodes a component of the delta-endotoxin of Bacillus thuringiensis subsp. israelensis. By S1 nuclease mapping and primer extension analysis, we have identified the transcriptional...

Comparative analysis of functional and structural features in the primase-dependent priming signals, G sites, from phages and plasmids.

Tanaka, K, Rogi, T, Hiasa, H, Miao, D M, Honda, Y, Nomura, N, ...

The primase-dependent priming signals, G sites, are directly recognized by the Escherichia coli primase (dnaG gene product) and conduct the synthesis of primer RNAs. In nucleotide sequence and...

Cloning and sequencing of an Escherichia coli gene, nlp, highly homologous to the ner genes of bacteriophages Mu and D108.

Choi, Y L, Nishida, T, Kawamukai, M, Utsumi, R, Sakai, H, Komano, T

An nlp (Ner-like protein) gene was isolated from Escherichia coli. The nucleotide sequence of a 1,342-base-pair chromosomal DNA fragment containing the nlp gene was analyzed. It contained two open...

Inhibitory effect of adenosine 3',5'-phosphate on cell division of Escherichia coli K-12 mutant derivatives.

Utsumi, R, Tanabe, H, Nakamoto, Y, Kawamukai, M, Sakai, H, Himeno, M, ...

Cell division of Escherichia coli K-12 strain PA3092 was inhibited by the addition of adenosine 3',5'-phosphate (cAMP), and the cellular morphology was changed from rods into filaments. Nucleoids in...

Integration is essential for efficient gene expression of human immunodeficiency virus type 1.

Sakai, H, Kawamura, M, Sakuragi, J, Sakuragi, S, Shibata, R, Ishimoto, A, ...

A mutant of human immunodeficiency virus type 1 which carries a frameshift insertion in the integrase/endonuclease region of pol gene was constructed in vitro. Upon transfection into cells, although...

Cell-dependent requirement of human immunodeficiency virus type 1 Vif protein for maturation of virus particles.

Sakai, H, Shibata, R, Sakuragi, J, Sakuragi, S, Kawamura, M, Adachi, A

A highly sensitive single-round infection assay using a bacterial chloramphenicol acetyltransferase was developed to analyze an early stage of human immunodeficiency virus type 1 replication. By a...

Generation of a chimeric human and simian immunodeficiency virus infectious to monkey peripheral blood mononuclear cells.

Shibata, R, Kawamura, M, Sakai, H, Hayami, M, Ishimoto, A, Adachi, A

We constructed five chimeric clones between human immunodeficiency virus type 1 (HIV-1) and simian immunodeficiency virus (SIVMAC) and four SIVMAC mutants by recombinant DNA techniques. Three...

Functional comparison of transactivation by human retrovirus rev and rex genes.

Sakai, H, Siomi, H, Shida, H, Shibata, R, Kiyomasu, T, Adachi, A

The effect of rev-responsive element deletion on human immunodeficiency virus type 1 (HIV-1) and type 2 (HIV-2) gene expression was examined. The phenotypes of HIV-1 and HIV-2 provirus DNAs lacking...

Generation and characterization of infectious chimeric clones between human immunodeficiency virus type 1 and simian immunodeficiency virus from an African green monkey.

Shibata, R, Sakai, H, Kiyomasu, T, Ishimoto, A, Hayami, M, Adachi, A

A series of chimeric clones of human immunodeficiency virus type 1 and simian immunodeficiency virus isolated from an African green monkey was constructed in vitro. In transient transfection...

Identification of feline immunodeficiency virus rev gene activity.

Kiyomasu, T, Miyazawa, T, Furuya, T, Shibata, R, Sakai, H, Sakuragi, J, ...

We constructed 16 deletion mutants from an infectious molecular clone of feline immunodeficiency virus (FIV) and a reporter plasmid carrying the bacterial chloramphenicol acetyltransferase (CAT) gene...

Construction and characterization of an infectious DNA clone and of mutants of simian immunodeficiency virus isolated from the African green monkey.

Shibata, R, Miura, T, Hayami, M, Sakai, H, Ogawa, K, Kiyomasu, T, ...

We constructed a full-length molecular clone of simian immunodeficiency virus from an African green monkey. Upon transfection, this clone directed the production of virus particles cytopathic and...

Mutational analysis of the human immunodeficiency virus type 2 (HIV-2) genome in relation to HIV-1 and simian immunodeficiency virus SIV (AGM).

Shibata, R, Miura, T, Hayami, M, Ogawa, K, Sakai, H, Kiyomasu, T, ...

We constructed an infectious molecular clone of the human immunodeficiency virus type 2 (HIV-2) and generated nine frameshift mutants corresponding to nine open reading frames identified so far....

Complementation of the rev gene mutation among human and simian lentiviruses.

Sakai, H, Shibata, R, Miura, T, Hayami, M, Ogawa, K, Kiyomasu, T, ...

The functional exchangeability of the rev gene was assessed in transient transfection experiments by using in vitro-constructed rev and gag mutants of the following three primate lentiviruses: human...

Cofilin is a component of intranuclear and cytoplasmic actin rods induced in cultured cells.

Nishida, E, Iida, K, Yonezawa, N, Koyasu, S, Yahara, I, Sakai, H

Incubation of cultured cells under specific conditions induces a dramatic change in the actin organization: induction of intranuclear and/or cytoplasmic actin rods (actin paracrystal-like...

The interaction of RepC initiator with iterons in the replication of the broad host-range plasmid RSF1010.

Miao, D M, Sakai, H, Okamoto, S, Tanaka, K, Okuda, M, Honda, Y, ...

The replication origin of the broad host-range plasmid RSF1010 contains 3.5 copies of a 20mer iteron sequence that bind specifically to the plasmid-encoded initiator, RepC. Here we demonstrated that...

Functional difference between the two oppositely oriented priming signals essential for the initiation of the broad host-range plasmid RSF1010 DNA replication.

Tanaka, K, Kino, K, Taguchi, Y, Miao, D M, Honda, Y, Sakai, H, ...

The broad host-range plasmid RSF1010 contains two oppositely oriented priming signals, ssiA and ssiB, for DNA synthesis dependent on the origin of vegetative DNA replication (oriV). If either ssiA or...

A base-paired hairpin structure essential for the functional priming signal for DNA replication of the broad host range plasmid RSF1010.

Miao, D M, Honda, Y, Tanaka, K, Higashi, A, Nakamura, T, Taguchi, Y, ...

The two single-strand DNA initiation signals, ssiA(RSF1010) and ssiB(RSF1010) of the broad host-range plasmid RSF1010 contain proposed stem-loop structures. Nine single base-change mutations in the...

DnaG-dependent priming signals can substitute for the two essential DNA initiation signals in oriV of the broad host-range plasmid RSF1010.

Honda, Y, Nakamura, T, Tanaka, K, Higashi, A, Sakai, H, Komano, T, ...

Broad host-range plasmid RSF1010 contains in the oriV region two DNA initiation signals, ssiA(RSF1010) and ssiB(RSF1010), which are essential for plasmid replication. Each of ssiA and ssiB could be...

Structural features of the priming signal recognized by primase: mutational analysis of the phage G4 origin of complementary DNA strand synthesis.

Hiasa, H, Sakai, H, Komano, T, Godson, G N

45 mutations (insertion, deletion and base substitution) of the G4 Goric were tested for their functional activity in M13 and R199 in vivo. The critical mutants were also assayed for their ability to...

Structural and functional features of cis-acting sequences in the basic replicon of plasmid ColIb-P9.

Tanaka, K, Sakai, H, Honda, Y, Nakamura, T, Higashi, A, Komano, T

We have structurally and functionally analyzed the cis-elements essential for ColIb-P9 plasmid DNA replication. The putative oriV region encompassed a region of 172 base pairs (bp) located 152 bp...

Site-specific AT-cluster insertions in the mitochondrial 15S rRNA gene of the yeast S. cerevisiae.

Hüttenhofer, A, Sakai, H, Weiss-Brummer, B

By comparing the mitochondrial 15S rRNA sequences of four wildtype yeast strains together with their respective secondary structures, with those of the 16S-like ribosomal RNA from other organisms we...

Growth and DNA synthesis of bacteriophage phi x174 in a dnaP mutant of Escherichia coli.

Mano, Y, Sakai, H, Komano, T

phi X174am3trD, a temperature-resistant mutant of bacteriophage phi X174am3, exhibited a reduced ability to grow in a dnaP mutant, Escherichia coli KM107, at the restrictive temperature (43 degrees...

Two mammalian heat shock proteins, HSP90 and HSP100, are actin-binding proteins.

Koyasu, S, Nishida, E, Kadowaki, T, Matsuzaki, F, Iida, K, Harada, F, ...

Two high molecular weight heat shock proteins, HSP90 (Mr, 90,000) and HSP100 (Mr, 100,000), were separately purified from extracts of cultured cells of a mouse lymphoma cell line, L5178Y. Both of the...

Thiopeptin, a New Feed Additive Antibiotic: Microbiological and Chemical Studies

Miyairi, N., Miyoshi, T., Aoki, H., Kohsaka, M., Ikushima, H., Kunugita, K., ...

The thiopeptins are a new group of sulfur-containing peptide antibiotics produced by Streptomyces tateyamensis. The antibiotic consists of a major component (designated as thiopeptin B) and four...

Xenopus M phase MAP kinase: isolation of its cDNA and activation by MPF.

Gotoh, Y, Moriyama, K, Matsuda, S, Okumura, E, Kishimoto, T, Kawasaki, H, ...

MAP kinase is activated and phosphorylated during M phase of the Xenopus oocyte cell cycle, and induces the interphase-M phase transition of microtubule dynamics in vitro. We have carried out...

Immunohistochemical colocalization of glycoxidation products and lipid peroxidation products in diabetic renal glomerular lesions. Implication for glycoxidative stress in the pathogenesis of diabetic nephropathy.

Horie, K, Miyata, T, Maeda, K, Miyata, S, Sugiyama, S, Sakai, H, ...

Advanced glycation end products (AGEs) include a variety of protein adducts whose accumulation alters the structure and function of tissue proteins and stimulates cellular responses. They have been...

A mesangium-predominant gene, megsin, is a new serpin upregulated in IgA nephropathy.

Miyata, T, Nangaku, M, Suzuki, D, Inagi, R, Uragami, K, Sakai, H, ...

Mesangial cells play an important role in maintaining a structure and function of the glomerulus and in the pathogenesis of glomerular diseases. To identify a specific gene expressed in human...

Simultaneous Detection of Staphylococcus aureus and Coagulase-Negative Staphylococci in Positive Blood Cultures by Real-Time PCR with Two Fluorescence Resonance Energy Transfer Probe Sets

Sakai, H., Procop, G. W., Kobayashi, N., Togawa, D., Wilson, D. A., Borden, L., ...

A real-time PCR assay that uses two fluorescence resonance energy transfer probe sets and targets the tuf gene of staphylococci is described here. One probe set detects the Staphylococcus genus,...

Xenopus MAP kinase activator: identification and function as a key intermediate in the phosphorylation cascade.

Matsuda, S, Kosako, H, Takenaka, K, Moriyama, K, Sakai, H, Akiyama, T, ...

MAP kinase is thought to play a pivotal role not only in the growth factor-stimulated signalling pathway but also in the M phase phosphorylation cascade downstream of MPF. MAP kinase is fully active...

C-terminal topology of gastric H+,K(+)-ATPase.

Asano, S, Arakawa, S, Hirasawa, M, Sakai, H, Ohta, M, Ohta, K, ...

An antibody was prepared against a peptide corresponding to residues 1024-1034 (the putative C-terminus) of the alpha-subunit of hog gastric H+,K(+)-ATPase. The antibody bound to a 95 kDa band of...

Activation of complement by renal tissues from patients with IgA nephropathy.

Tomino, Y, Endoh, M, Nomoto, Y, Sakai, H

In a study of complement activation by renal tissues, renal biopsy specimens were obtained from patients with IgA nephropathy and other glomerular diseases. These specimens were incubated with...

Studies on the interaction between actin and cofilin purified by a new method.

Yonezawa, N, Nishida, E, Maekawa, S, Sakai, H

Cofilin is a 21,000-Mr actin-binding protein that widely exists in mammalian tissues. (1) A new purification procedure for porcine brain cofilin has been developed that involves (NH4)2SO4...

Three immunoidentical cytochromes P-450 from liver microsomes of phenobarbital-treated rats.

Sakai, H, Hino, Y, Minakami, S

Three forms of cytochrome P-450 were purified to homogeneity from liver microsomes of Wistar-strain rats treated with phenobarbital. They had minimum mol.wts. of 52 000, 53 000 and 54 000 as...

Effects of dibutyryl cyclic AMP on the syntheses of dolichol-linked saccharides and glycoproteins in cultured hepatoma cells. Correlation with the effect on the adhesiveness of the cells.

Okamoto, Y, Sakai, H, Sato, J, Akamatsu, N

When the hepatoma cells (AH 70Btc, Clone 10-5) were cultured in the presence of 1 mM-dibutyryl cyclic AMP for 2 days, the incorporation of [14C]glucosamine into protein was increased over 2-fold. At...

Thromboxane A2, released by the anti-tumour drug irinotecan, is a novel stimulator of Cl- secretion in isolated rat colon.

Sakai, H, Sato, T, Hamada, N, Yasue, M, Ikari, A, Kakinoki, B, ...

1. A camptothecin derivative, irinotecan (Cpt-11), is a topoisomerase I inhibitor and has a strong activity against a broad range of human cancer. One of the side-effects of this drug is diarrhoea....

Small-conductance Cl- channels in rabbit parietal cells activated by prostaglandin E2 and inhibited by GTP gamma S.

Sakai, H, Takeguchi, N

1. Small-conductance, sub-picosiemens (sub-pS) Cl- channels in the basolateral membrane of non-stimulated parietal cells in isolated rabbit gastric glands were studied by whole-cell patch-clamp and...

Arachidonic acid and prostaglandin E2 activate small-conductance Cl- channels in the basolateral membrane of rabbit parietal cells.

Sakai, H, Okada, Y, Morii, M, Takeguchi, N

1. Cl- channels in the basolateral membrane of non-stimulated parietal cells in isolated rabbit gastric glands were studied by patch-clamp and noise analysis techniques. 2. Voltage-independent...

An Aspergillus awamori acetylesterase: purification of the enzyme, and cloning and sequencing of the gene.

Koseki, T, Furuse, S, Iwano, K, Sakai, H, Matsuzawa, H

An inducible acetylesterase was purified from the culture medium of Aspergillus awamori strain IFO4033 growing on wheat-bran culture by ion-exchange, gel-filtration and hydrophobic-interaction...

Molecular cloning and cell-cycle-dependent expression of a novel NIMA (never-in-mitosis in Aspergillus nidulans)-related protein kinase (TpNrk) in Tetrahymena cells.

Wang, S, Nakashima, S, Sakai, H, Numata, O, Fujiu, K, Nozawa, Y

With the intention of investigating the signal-transduction pathway that mediates the cold-stress response in Tetrahymena, we isolated a gene that encodes a novel protein kinase of 561 amino acids,...

Comprehensive evaluation of variability in nicotine metabolism and CYP2A6 polymorphic alleles in four ethnic populations

Nakajima, Miki, Fukami, T., Yamanaka, H., Higashi, E., Sakai, H., Yoshida, R., ...

Human cytochrome P450 (CYP) 2A6 metabolizes nicotine to cotinine and is a possible modulator of nicotine addiction. Quantitative and qualitative differences in nicotine addiction have been observed...

Surface properties of LDL-binding lymphocytes in human peripheral blood.

Hiramatsu, K, Sakai, H, Endoh, M, Arimori, S

Surface properties of low density lipoprotein (LDL)-binding lymphocytes were evaluated to determine whether LDL binds with a subpopulation of human peripheral blood lymphocytes (PBL). B- and T-cell...

Fibroblasts from the inner granulation tissue of the pseudocapsule in hips at revision arthroplasty induce osteoclast differentiation, as do stromal cells

Sakai, H, Jingushi, S, Shuto, T, Urabe, K, Ikenoue, T, Okazaki, K, ...

Background: It has previously been shown that many osteoclast precursors are included in the granulation tissue within the pseudocapsule obtained at revision arthroplasty from hips with osteolysis....

Cathepsins D and E in normal, metaplastic, dysplastic, and carcinomatous gastric tissue: an immunohistochemical study.

Saku, T, Sakai, H, Tsuda, N, Okabe, H, Kato, Y, Yamamoto, K

Immunohistochemical distributions of cathepsins D and E were determined in normal mucosa, metaplastic, dysplastic, and cancerous lesions of the human stomach. Cathepsins D and E were localised in the...

PDX1 homeobox protein expression in pseudopyloric glands and gastric carcinomas

Sakai, H, Eishi, Y, Li, X-L, Akiyama, Y, Miyake, S, Takizawa, T, ...

Background and aims: Although it has been reported that intestinal metaplasia implicated in gastric carcinogenesis is induced by the ParaHox gene CDX2, it is unclear which genes are responsible for...

Immunofluorescent studies on S-protein in glomeruli from patients with IgA nephropathy.

Tomino, Y., Yagame, M., Eguchi, K., Nomoto, Y., Sakai, H.

Detection of S-protein, which is a regulatory component of the membrane attack complex (MAC), and of C9 in glomeruli by immunofluorescence in 11 of 15 patients with IgA nephropathy is described. The...

Increase of IgA-specific switch T cells in patients with IgA nephropathy.

Sakai, H, Miyazaki, M, Endoh, M, Nomoto, Y

Enumeration and functional analysis of CD4+ T cells with receptors for the Fc portion of IgA (i.e. T alpha 4 cells) in the peripheral blood of patients with IgA nephropathy, their relatives and...

Rheumatoid factor and glomerulonephritis

Miyazaki, M., Endoh, M., Suga, T., Yano, N., Kuramoto, T., Matsumoto, Y., ...

It is presently unknown whether rheumatoid factors have a pathogenic role in the development of various types of glomerulonephritis with immune deposits. Three isotypes of rheumatoid factors (RFs),...

In vivo alteration of antibody production in patients with IgA nephropathy.

Endoh, M, Suga, T, Miura, M, Tomino, Y, Nomoto, Y, Sakai, H

Augmentation of IgA production has been postulated for the development of IgA nephropathy. An influenza HA vaccine was administered to healthy adults and patients with IgA nephropathy to elucidate if...

Detection of polymeric IgA in glomeruli from patients with IgA nephropathy.

Tomino, Y, Sakai, H, Miura, M, Endoh, M, Nomoto, Y

A study on the detection of polymeric IgA in glomeruli from renal biopsy specimens in patients with IgA nephropathy is described. Renal biopsy specimens were obtained from patients with IgA...

Cross-reactivity of IgA antibodies between renal mesangial areas and nuclei of tonsillar cells in patients with IgA nephropathy.

Tomino, Y, Sakai, H, Endoh, M, Suga, T, Miura, M, Kaneshige, H, ...

A study on autoradiographical analysis of antigenic sites in patients with IgA nephropathy is described. Renal biopsy specimens were obtained from patients with IgA nephropathy. These specimens were...

Increase of IgA specific helper T alpha cells in patients with IgA nephropathy.

Sakai, H, Endoh, M, Tomino, Y, Nomoto, Y

Patients with IgA nephropathy show an emergence of IgA dominant circulating immune complexes (CIC) as well as increased levels of serum IgA and/or IgA bearing peripheral blood lymphocytes. In order...

Decrease of IgA-specific suppressor T cell activity in patients with IgA nephropathy.

Sakai, H, Nomoto, Y, Arimori, S

The activity of IgA-specific suppressor T cells was lower in eight patients with IgA nephropathy than in six patients with chronic proliferative glomerulonephritis without glomerular deposition of...

Characterization of an acidic nuclear protein recognized by autoantibodies in sera from patients with IgA nephropathy.

Nomoto, Y, Suga, T, Miura, M, Nomoto, H, Tomino, Y, Sakai, H

A nuclear antigen is recognized by autoantibodies in the sera of some patients with IgA nephropathy. Using these autoantibodies as a reagent, this antigen was purified 77.2-fold by ammonium sulfate...

Detection of IgA-class circulating immune complexes (CIC) in sera from patients with IgA nephropathy using a solid-phase anti-C3 Facb enzyme immunoassay (EIA).

Yagame, M, Tomino, Y, Miura, M, Tanigaki, T, Suga, T, Nomoto, Y, ...

The detection of circulating immune complexes (CIC) in sera from patients with IgA nephropathy is described. A solid-phase anti-C3 Facb enzyme immunoassay (EIA) was employed for detection of IgA-,...

Altered production of IgE and IgA induced by IL-4 in peripheral blood mononuclear cells from patients with IgA nephropathy.

Yano, N, Endoh, M, Miyazaki, M, Yamauchi, F, Nomoto, Y, Sakai, H

In order to elucidate the factors responsible for altered immunoglobulin production in patients with IgA nephropathy (IgAN), the in vitro effects of IL-4 and interferon-gamma (IFN-gamma) on the...

Cold reacting anti-nuclear factor (ANF) in families of patients with IgA nephropathy.

Nomoto, Y, Miura, M, Suga, T, Endoh, M, Tomino, Y, Sakai, H

The emergence of cold reacting anti-nuclear factor (ANF) in families of patients with IgA nephropathy was examined to determine whether some immunological alterations among family members affect the...

Solubilization of intraglomerular deposits of IgG immune complexes by human sera or gamma-globulin in patients with lupus nephritis.

Tomino, Y, Sakai, H, Takaya, M, Miura, M, Suga, T, Endoh, M, ...

A study of the solubilization of glomerular deposition of IgG immune complexes by sera from patients with lupus nephritis is described. Renal biopsy specimens were obtained from 11 patients with...

Immunofluorescent studies on alpha 2-plasmin inhibitor (alpha 2-PI) in glomeruli from patients with IgA nephropathy.

Miura, M, Tomino, Y, Yagame, M, Endoh, M, Suga, T, Nomoto, Y, ...

Detection of alpha 2-plasmin inhibitor (alpha 2-PI) and/or fibrinogen in glomeruli by immunofluorescence in 26 patients with IgA nephropathy was described. The present study showed that glomerular...

In vitro reactivity of human lymphocytes in chronic uraemia: analysis and interpretation

Daniels, J. C., Sakai, H., Remmers, A. R., Sarles, H. E., Fish, J. C., Cobb, E. K., ...

Altered cellular immunity complicating chronic uraemia includes lymphocytopenia, thymic atrophy, impaired allograft rejection and delayed hypersensitivity in skin tests, diminished appearances of...

Immunopathologic and histologic studies on benign recurrent hematuria. Clinicopathologic similarities with IgA nephropathy.

Nomoto, Y., Sakai, H., Arimori, S., Iwagaki, H., Osamura, R. Y., Hata, J., ...

From a series of 152 renal biopsy specimens examined by light, immunofluorescence, and electron microscopy, nine specimens were identified as being from patients with BRH. Histopathologic changes in...

The effects of diltiazem on hepatic drug metabolizing enzymes in man using antipyrine, trimethadione and debrisoquine as model substrates.

Sakai, H, Kobayashi, S, Hamada, K, Iida, S, Akita, H, Tanaka, E, ...

Six healthy male subjects were given single oral doses of antipyrine (7 mg kg-1), trimethadione (4 mg kg-1) and debrisoquine (10 mg) before and during diltiazem treatment (30 mg three times daily...

The mechanism of acidic pH-induced contraction in aortae from SHR and WKY rats enhanced by increasing blood pressure.

Furukawa, K., Komaba, J., Sakai, H., Ohizumi, Y.

1. Effect of pH on vascular smooth muscle contraction was analyzed by use of biochemical and pharmacological techniques. 2. In the aorta isolated from spontaneously hypertensive rats (SHR) decreasing...

A cyclic GMP-dependent housekeeping Cl- channel in rabbit gastric parietal cells activated by a vasodilator ecabapide.

Sakai, H., Ikari, A., Kumano, E., Takeguchi, N.

1. The membrane potential of rabbit gastric parietal cells is dominated by a Cl- channel with a subpicosiemens single channel conductance in the basolateral membrane. The effects of...

Analysis of the structure and expression of the augmenter of liver regeneration (ALR) gene.

Giorda, R., Hagiya, M., Seki, T., Shimonishi, M., Sakai, H., Michaelson, J., ...

BACKGROUND: The gene encoding the hepatotrophic factor Augmenter of Liver Regeneration (ALR) has recently been cloned in the rat. The availability of the mouse form of ALR would allow the analysis of...

Comparison of low attenuation areas on computed tomographic scans between inner and outer segments of the lung in patients with chronic obstructive pulmonary disease: incidence and contribution to lung function

Nakano, Y, Sakai, H, Muro, S, Hirai, T, Oku, Y, Nishimura, K, ...

BACKGROUND—The low attenuation areas on computed tomographic (CT) scans have been reported to represent emphysematous changes of the lung. However, the regional distribution of emphysema between...

Nuclear factor‐κB and caspases co‐operatively regulate the activation and apoptosis of human macrophages

Hida, A, Kawakami, A, Nakashima, T, Yamasaki, S, Sakai, H, Urayama, S, ...

Accumulating evidence suggests that macrophages function as major effector cells in the pathological process of various human diseases. We examined here the role of nuclear factor‐κB (NF‐κB)...

Video-Assisted Thoracoscopic Surgery in Patients With Clinically Resectable Lung Tumors

Sakai, H., Borgstein, P. J., Cuesta, M. A., Meijer, S., Van Mourik, J. C., Sutedja, G., ...

To investigate the feasibility of thoracoscopic resection, a pilot study was performed in patients with clinically resectable lung tumors. In 40 patients, Video-assisted thoracic surgery (VATS) was...

Endoscopic Diagnosis and Treatment of a Case of Respiratory Papillomatosis

Hirano, T., Konaka, C., Okada, S., Shibanuma, H., Shimizu, E., Okunaka, T., ...

Respiratory papilloma is a rare lesion that arises in the larynx, trachea and bronchus. We describe a patient with laryngeal papilloma that spread to the trachea and which was effectively treated by...

Histopathological and immunohistochemical studies of lenticules after epikeratoplasty for keratoconus

Nakamura, H, Riley, F, Sakai, H, Rademaker, W, Edward, D P

Aims: To examine histopathological and immunohistochemical changes in lenticules and host of corneal buttons from patients who previously underwent epikeratoplasty for keratoconus.

Aldosterone-producing microadenoma in a patient with primary aldosteronism.

Kaneshige, H., Endoh, M., Nomoto, Y., Sakai, H., Arimori, S.

A 54-year-old patient was found to have an aldosterone-producing microadenoma measuring 2.5 mm in diameter. Although adrenal venography by selective catheterization had failed to demonstrate the...

Precise Fabrication Of X-Band Detuned Accelerating Structure For Linear Collider

T. Higo, H. Sakai, Y. Higashi, T. Takatomi, S. Koike

microns along 1.2m stacking was obtained though a severe trouble happened to the jiggings. Based on these experiences, the possibility of a precise fabrication method for the detuned structure in...

Photokilling of T-24 human bladder cancer cells with titanium dioxide.

Kubota, Y., Shuin, T., Kawasaki, C., Hosaka, M., Kitamura, H., Cai, R., ...

A photoexcited titanium dioxide surface has a strong ability to decompose water into hydrogen and oxygen. We have studied this effect in order to use it to kill cancer cells in vitro and in vivo. A...