T Kuroda, H Sasaki, T Tateishi, K Maeda, Y Yasumuro, Y Manabe, ...
aids based on wearable/ubiquitous computing – aiming at
Destabilization of mixed Rossby gravity waves and the formation of equatorial zonal jets (2008)
HUA, Bach-Lien, D'ORGEVILLE, Marc, FRUMAN, Mark, MENESGUEN, Claire, SCHOPP, Richard, KLEIN, Patrice, ...
stability of mixed Rossby gravity (MRG) waves has been investigated numerically using three-dimensionally consistent high-resolution Simulations of the continuously stratified primitive equations....
XI. Neuroenergetics: Relevance for Functional Brain Imaging, eds P. J. (2008)
In Eukaryotes, R. Y. Tsien, K. Mikoshiba, J. Altman, R. Caminiti, ...
The HFSP workshops were initiated by Michel Cuénod (Secretary-General, HFSPO) with the support of the Board of Trustees and the Council of Scientists. The workshops, held in English, are organized...
KOMORI, N, OHFUCHI, W, TAGUCHI, B, SASAKI, H, KLEIN, Patrice
In order to investigate the deep ocean inertia-gravity waves, a high-resolution global coupled atmosphere-ocean simulation is carried out with a coupling interval of 20 minutes. Large (similar to...
Intraseasonal meridional current variability in the eastern equatorial Indian Ocean (2008)
Ogata, T., Sasaki, H., Murty, V.S.N., Sarma, M.S.S., Masumoto, Y.
Intraseasonal variability in meridional current in the eastern equatorial Indian Ocean is investigated by use of results from a high-resolution ocean general circulation model. Both the simulated and...
OPA-9: French experiments on the Earth Simulator and Teraflop workbench timings (2008)
Masson, S., Foujols, M-A., Madec, G., Hua, L., Levy, M., Sasaki, H., ...
D'ORGEVILLE, Marc, HUA, Bach-Lien, SASAKI, H
The response of the deep equatorial ocean to an oscillatory baroclinic western boundary current is investigated in a continuously stratified primitive equation model. The symmetry of the current...
Sasaki, H., Takagi, S., Shikida, M., Sato, K.
We have previously proposed an arrayed vertical motion system based on a tulip-shaped electrostatic clutch for producing haptic displays. The system has an advantage in that it is able to...
Electrostatic Latch Mechanism for Handling Projection on Arrayed Vertical Motion System (2007)
Takagi, S., Sasaki, H., Shikida, M., Sato, K.
We have previously proposed an arrayed vertical motion system based on a tulip-shaped electrostatic clutch for producing haptic displays. The system has an advantage in that it is able to...
Decadal variability in the Kuroshio-Oyashio Extension simulated in an eddy-resolving OGCM (2006)
Nonaka, M, Nakamura, H, Tanimoto, Y, Kagimoto, T, Sasaki, H, 谷本, 陽一
Through analysis of a hindcast integration of an eddy-resolving quasi-global ocean general circulation model, decadal variability in the Kuroshio–Oyashio Extension region is investigated, with...
Decadal variability in the Kuroshio-Oyashio Extension simulated in an eddy-resolving OGCM (2006)
Nonaka, M, Nakamura, H, Tanimoto, Y, Kagimoto, T, Sasaki, H
Through analysis of a hindcast integration of an eddy-resolving quasi-global ocean general circulation model, decadal variability in the Kuroshio–Oyashio Extension region is investigated, with...
Decadal variability in the Kuroshio-Oyashio Extension simulated in an eddy-resolving OGCM (2006)
Nonaka, M, Nakamura, H, Tanimoto, Y, Kagimoto, T, Sasaki, H
Through analysis of a hindcast integration of an eddy-resolving quasi-global ocean general circulation model, decadal variability in the Kuroshio–Oyashio Extension region is investigated, with...
Growth of anthracene derivative thin films with a π-stacking structure (2006)
Sasaki, H., Wakayama, Y., Chikyow, T., Barrena, E., Dosch, H., Kobayashi, K.
Sasaki, H., Shikida, M., Sato, K.
This paper proposes a novel type mechanical transmission system for driving arrayed elements. The main advantage of this system is that it is able to operate individually arrayed elements with...
Nonlinear rheology and retraction of entangled thread-like micelles (2006)
Takagi, A, Sasaki, H, Kuriyama, A, Matsumiya, Y, Inoue, T, Watanabe, H
Maekawa, S., Horie, T., Yamauchi, T., Sawaya, T., Ishikawa, M., Hayakawa, M., ...
A superimposed epoch analysis has been undertaken, in order to find the correlation of the ionospheric perturbations with seismic activity. We take the wave path from the Japanese LF transmitter...
Maekawa, S., Horie, T., Yamauchi, T., Sawaya, T., Ishikawa, M., Hayakawa, M., ...
A superimposed epoch analysis has been undertaken, in order to find the correlation of the ionospheric perturbations with seismic activity. We take the wave path from the Japanese LF transmitter...
Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study. (2005)
Jonsson, O, Damji, K F, Jonasson, F, Arnarsson, A, Eysteinsson, T, Sasaki, H, ...
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
KING,N. W., Jones,L. D., Sasaki,H., Schaffner,F.
The administration of intravenous fat emulsion to rats produces dilatation of the hepatic rough endoplasmic reticulum similar to that which occurs in choline deficiency. In the present study the...
Tsuchiya, M., Nakao, H., Katoh, T., Sasaki, H., Hiroshima, M., Tanaka, T., ...
BACKGROUND: Endometriosis, an estrogen-dependent disease, is believed to be influenced by multiple genetic and environmental factors. Here, we evaluated whether the risk and severity of endometriosis...
Tsuchiya, M., Nakao, H., Katoh, T., Sasaki, H., Hiroshima, M., Tanaka, T., ...
BACKGROUND: Endometriosis, an estrogen-dependent disease, is believed to be influenced by multiple genetic and environmental factors. Here, we evaluated whether the risk and severity of endometriosis...
During anatomical practice between 2001-2002 at the Tokyo Women¿s Medical University, a defect in the hepatic segment of the inferior vena cava was encountered in a 94-year-old male cadaver....
During anatomical practice between 2001-2002 at the Tokyo Women¿s Medical University, a defect in the hepatic segment of the inferior vena cava was encountered in a 94-year-old male cadaver....
Prevalence of open-angle glaucoma in Iceland: Reykjavik Eye Study (2003)
Jonasson, F, Damji, K F, Arnarsson, A, Sverrisson, T, Wang, L, Sasaki, H, ...
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
Caveolin-3 gene mutation in Japanese with rippling muscle disease (2003)
Yabe, Ichiro, Kawashima, A, Kikuchi, S, Higashi, T, Fukazawa, T, Hamada, T, ...
Objectives: Rippling muscle disease (RMD) is a rare myopathy characterized by percussion-induced rapid muscle contractions, muscle mounding, and rippling. Recently a caveolin-3 gene (CAV3) mutation...
Caveolin-3 gene mutation in Japanese with rippling muscle disease (2003)
Yabe, Ichiro, Kawashima, A, Kikuchi, S, Higashi, T, Fukazawa, T, Hamada, T, ...
Objectives: Rippling muscle disease (RMD) is a rare myopathy characterized by percussion-induced rapid muscle contractions, muscle mounding, and rippling. Recently a caveolin-3 gene (CAV3) mutation...
Caveolin-3 gene mutation in Japanese with rippling muscle disease (2003)
Yabe, Ichiro, Kawashima, A, Kikuchi, S, Higashi, T, Fukazawa, T, Hamada, T, ...
Objectives: Rippling muscle disease (RMD) is a rare myopathy characterized by percussion-induced rapid muscle contractions, muscle mounding, and rippling. Recently a caveolin-3 gene (CAV3) mutation...
Protein adsorption on carbon-negative ion (C-)-implanted polystyrene as neuronal guidance. (2003)
Sato, H, Tsuji, H, Izukawa, M, Sasaki, H, Utsumi, Y, Gotoh, Y, ...
Selective neurite outgrowth on silver negative ion (Ag-)-implanted polystyrene surfaces (2003)
Sato, H, Tsuji, H, Sasaki, H, Ikemura, S, Gotoh, Y, Ishikawa, J, ...
Gudmundsdottir, E, Jonasson, F, Jonsson, V, Stefansson, E, Sasaki, H, Sasaki, K
To access publisher full text version of this article. Please click on the hyperlink in Additional Links field
WORKSHOP VIII THE REGULATION OF SLEEP EDITORS (2000)
W. Fangman, T. Kishimoto, M. Kohiyama, C. Coath, S. Ang, R. Behringer, ...
To be published:
Sekikawa, A, Eguchi, H, Tominaga, M, Manaka, H, Sasaki, H, Chang, YF, ...
An Experimental Study on BEM-Based Cortical Imaging of Human SEP Activities (1998)
Zhang, X., Towle, V. L., Sasaki, H., Lian, J., Li, G. L.
The boundary element method (BEM) based cortical imaging technique (CIT) has been applied to an experimental study on human somatorsensory evoked potentials (SEPs) recorded from a patient. The...
Acoustic properties of dialysed kidney by scanning acoustic microscopy (1997)
Sasaki, H, Saijo, Y, Tanaka, M, Nitta, S, Terasawa, Y, Yambe, T, ...
The observation of the muonic decay D$^{\pm}_{s}$ --> $\mu^{\pm}\nu_{\mu}$ (1993)
Aoki, S, Baroni, Giustina, Bisi, V, Breslin, A C, Catanesi, M G, Chiba, K, ...
The first observation of the muonic decay D$^{\pm}_{s}$ --> $\mu^{\pm}\nu_{\mu}$ (1992)
Aoki, S, Baroni, Giustina, Bisi, V, Breslin, A C, Catanesi, M G, Chiba, K, ...
Charm production by 350 GeV/c $\pi^{-}$ interactions in nuclear emulsion (1992)
Aoki, S, Arnold, R, Baroni, Giustina, Bisi, V, Breslin, A C, Catanesi, M G, ...
Charm production by 350 GeV/c $\pi^-$ interactions in nuclear emulsion (1992)
Aoki, S., Arnold, R., Baroni, G., Bisi, V., Breslin, A.C., Catanesi, M.G., ...
Charm production by 350 GeV/c $\pi^-$ interactions in nuclear emulsion (1992)
Aoki, S., Arnold, R., Baroni, G., Bisi, V., Breslin, A.C., Catanesi, M.G., ...
Direct observation of the decay of beauty particles into charm particles (1990)
Albanese, J P, Alpe, V, Aoki, S, Arnold, R, Baroni, Giustina, Barth, Monique, ...
A hybrid experiment to search for beauty particles (1990)
Aoki, S, Arnold, R, Baroni, Giustina, Barth, Monique, Bartley, J H, Bertrand, D, ...
Some properties of charmed particles produced in pi-.nucleus interactions (1990)
Aoki, S, Arnold, R, Baroni, Giustina, Barth, Monique, Bertrand-Coremans, G H, Bisi, V, ...
MAGNET DESIGN STUDIES FOR THE TRIUMF KAON FACTORY PROPOSAL (1989)
Otter, A J, Ellstrom, L, Haddock, C, Harold, M, Reeve, P, Sasaki, H, ...
A hybrid experiment to search for beauty particles (1989)
Aoki, S., Arnold, R., Baroni, G., Barth, M., Bartley, J.H., Bertrand, D., ...
A hybrid experiment to search for beauty particles (1989)
Aoki, S., Arnold, R., Baroni, G., Barth, M., Bartley, J.H., Bertrand, D., ...
Some properties of charmed particles produced in $\pi^-$- nucleus interactions (1988)
Aoki, S., Arnold, R., Baroni, G., Barth, M., Bertrand-Coremans, G., Bisi, V., ...
Some properties of charmed particles produced in $\pi^-$- nucleus interactions (1988)
Aoki, S., Arnold, R., Baroni, G., Barth, M., Bertrand-Coremans, G., Bisi, V., ...
Direct observation of the decay of beauty particles into charm particles (1985)
Albanese, J.P., Alpe, V., Aoki, S., Arnold, R., Baroni, G., Barth, M., ...
Direct observation of the decay of beauty particles into charm particles (1985)
Albanese, J.P., Alpe, V., Aoki, S., Arnold, R., Baroni, G., Barth, M., ...
Application of Fracture Mechanics to Strength Analysis of Glued Lap Joints (1976)
KOMATSU, K., SASAKI, H., MAKU, T.
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。
Estimating Fracture Toughness from Nonlinear Load-Deflection Relation (1976)
KOMATSU, K., SASAKI, H., MAKU, T.
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。
KIMOTO, K., ISHIMORI, E., SASAKI, H., MAKU, T.
この論文は国立情報学研究所の学術雑誌公開支援事業により電子化されました。
Moore, T., Constancia, M., Zubair, M., Bailleul, B., Feil, R., Sasaki, H., ...
The mouse insulin-like growth factor 2 (Igf2) locus is a complex genomic region that produces multiple transcripts from alternative promoters. Expression at this locus is regulated by parental...
Mutoh, H, Fukuda, T, Kitamaoto, T, Masushige, S, Sasaki, H, Shimizu, T, ...
We have studied the effects of retinoic acid (RA) and thyroid hormone (3,3',5-triiodothyronine; T3) on platelet-activating factor receptor (PAFR) gene expression in intact rats and the ability of two...
Sasaki, H, Nakamura, M, Ohno, T, Matsuda, Y, Yuda, Y, Nonomura, Y
We examined the potential role of myosin and actin in the release of human immunodeficiency virus type 1 (HIV-1) from infected cells. Wortmannin (100 nM to 5 microM), an effective inhibitor of myosin...
Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.
Sumimoto, H, Kage, Y, Nunoi, H, Sasaki, H, Nose, T, Fukumaki, Y, ...
The phagocyte NADPH oxidase, dormant in resting cells, is activated during phagocytosis to produce superoxide, a precursor of microbicidal oxidants. The activated oxidase is a complex of...
Tanaka, N, Asao, H, Ohbo, K, Ishii, N, Takeshita, T, Nakamura, M, ...
The functional interleukin 2 (IL-2) receptors contain the beta and gamma chains which are necessary for the transduction of cell growth signals. Monoclonal antibodies specific for the beta chain and...
Taniguchi, S, Hirabayashi, Y, Inoue, T, Kanisawa, M, Sasaki, H, Komatsu, K, ...
It has been reported that SCID (severe combined immunodeficiency, scid/scid) mice are more radiosensitive than normal mice. In the present studies, graded doses of radiation were given to bone marrow...
K-sam gene encodes secreted as well as transmembrane receptor tyrosine kinase.
Katoh, M, Hattori, Y, Sasaki, H, Tanaka, M, Sugano, K, Yazaki, Y, ...
K-sam was first identified as a gene amplified in the stomach cancer cell line KATO-III. The size of the major transcript of the K-sam gene was 3.5 kilobases in KATO-III cells, and we have previously...
Ogawa, T, Oda, N, Nakashima, K, Sasaki, H, Hattori, M, Sakaki, Y, ...
As a step toward understanding the structure and function of phospholipases A2 (PLA2s), we isolated and sequenced several cDNAs encoding Trimeresurus flavoviridis venom PLA2 isozymes including two...
Establishment of a highly sensitive and specific exon-trapping system.
Hamaguchi, M, Sakamoto, H, Tsuruta, H, Sasaki, H, Muto, T, Sugimura, T, ...
We have established a highly sensitive and specific exon-trapping system (SETS) with a specific plasmid vector in which an exon in a given DNA segment is identified by its ability to remain as a...
Kato, S, Sasaki, H, Suzawa, M, Masushige, S, Tora, L, Chambon, P, ...
We describe here a novel class of cis-acting response elements for retinoid, vitamin D, and estrogen receptors which are widely spaced (10 to 200 bp) direct repeats (DRs) of the canonical 5'-AGGTCA...
Matsuzaki, K, Yoshitake, Y, Matuo, Y, Sasaki, H, Nishikawa, K
Two monoclonal antibodies (mAbs) against bovine heparin-binding growth factor II (HBGF-II)/basic fibroblast growth factor (bFGF) were obtained from mouse hybridoma cell lines. They were highly...
A HindIII polymorphism detected by the cDNA encoding amyloid beta protein of Alzheimer's disease.
Sasaki, H, Oishi, N, Furuya, H, Yoshioka, K, Yamada, T, Ogawa, S, ...
Specific DNA binding of the two chicken Deformed family homeodomain proteins, Chox-1.4 and Chox-a.
Sasaki, H, Yokoyama, E, Kuroiwa, A
The cDNA clones encoding two chicken Deformed (Dfd) family homeobox containing genes Chox-1.4 and Chox-a were isolated. Comparison of their amino acid sequences with another chicken Dfd family...
Activation of an imprinted Igf 2 gene in mouse somatic cell cultures.
Eversole-Cire, P, Ferguson-Smith, A C, Sasaki, H, Brown, K D, Cattanach, B M, Gonzales, F A, ...
The mouse insulin-like growth factor II gene (Igf 2), located on distal chromosome 7, is parentally imprinted such that the paternal allele is expressed while the maternal allele is transcriptionally...
Kaneko-Ishino, T, Kume, T U, Sasaki, H, Obinata, M, Oishi, M
By employing cell fusion between two genetically marked mouse erythroleukemia (MEL) cells in which an artificially introduced c-myc gene had been placed under the control of human metallothionein...
Identification of glucagon in the gastrointestinal tract.
Sasaki, H, Rubalcava, B, Baetens, D, Blazquez, E, Srikant, C B, Orci, L, ...
Gel filtration studies on Bio-Gel P-10 columns of a 50-fold purified porcine duodenal extract revealed a main peak of glucagon-like immunoreactivity (GLI) in the 2,900 mol wt zone and a smaller peak...
Furuya, H, Yoshioka, K, Sasaki, H, Sakaki, Y, Nakazato, M, Matsuo, H, ...
A Japanese family with atypical type I familial amyloidotic polyneuropathy (FAP) in Iiyama, Japan was studied. Most of the family members have dysfunctions in the central nervous system, in addition...
Ancestral Origins of the Machado-Joseph Disease Mutation: A Worldwide Haplotype Study
Gaspar, C., Lopes-Cendes, I., Hayes, S., Goto, J., Arvidsson, K., Dias, A., ...
Machado-Joseph disease (MJD) is an autosomal dominant neurodegenerative disorder originally described in families of Portuguese-Azorean ancestry. The cloning of the MJD1 gene allowed identification...
Sakai, T, Komuro, H, Katoh, Y, Sasaki, H, Momose-Sato, Y, Kamino, K
1. Employing an optical method for multiple-site simultaneous recording of electrical activity, we have determined the conduction velocity in cervical vagus nerve bundles isolated from 5- to...
Moore, T., Constancia, M., Zubair, M., Bailleul, B., Feil, R., Sasaki, H., ...
The mouse insulin-like growth factor 2 (Igf2) locus is a complex genomic region that produces multiple transcripts from alternative promoters. Expression at this locus is regulated by parental...
Mutoh, H, Fukuda, T, Kitamaoto, T, Masushige, S, Sasaki, H, Shimizu, T, ...
We have studied the effects of retinoic acid (RA) and thyroid hormone (3,3',5-triiodothyronine; T3) on platelet-activating factor receptor (PAFR) gene expression in intact rats and the ability of two...
Sasaki, H, Nakamura, M, Ohno, T, Matsuda, Y, Yuda, Y, Nonomura, Y
We examined the potential role of myosin and actin in the release of human immunodeficiency virus type 1 (HIV-1) from infected cells. Wortmannin (100 nM to 5 microM), an effective inhibitor of myosin...
Role of Src homology 3 domains in assembly and activation of the phagocyte NADPH oxidase.
Sumimoto, H, Kage, Y, Nunoi, H, Sasaki, H, Nose, T, Fukumaki, Y, ...
The phagocyte NADPH oxidase, dormant in resting cells, is activated during phagocytosis to produce superoxide, a precursor of microbicidal oxidants. The activated oxidase is a complex of...
Tanaka, N, Asao, H, Ohbo, K, Ishii, N, Takeshita, T, Nakamura, M, ...
The functional interleukin 2 (IL-2) receptors contain the beta and gamma chains which are necessary for the transduction of cell growth signals. Monoclonal antibodies specific for the beta chain and...
Taniguchi, S, Hirabayashi, Y, Inoue, T, Kanisawa, M, Sasaki, H, Komatsu, K, ...
It has been reported that SCID (severe combined immunodeficiency, scid/scid) mice are more radiosensitive than normal mice. In the present studies, graded doses of radiation were given to bone marrow...
K-sam gene encodes secreted as well as transmembrane receptor tyrosine kinase.
Katoh, M, Hattori, Y, Sasaki, H, Tanaka, M, Sugano, K, Yazaki, Y, ...
K-sam was first identified as a gene amplified in the stomach cancer cell line KATO-III. The size of the major transcript of the K-sam gene was 3.5 kilobases in KATO-III cells, and we have previously...
Ogawa, T, Oda, N, Nakashima, K, Sasaki, H, Hattori, M, Sakaki, Y, ...
As a step toward understanding the structure and function of phospholipases A2 (PLA2s), we isolated and sequenced several cDNAs encoding Trimeresurus flavoviridis venom PLA2 isozymes including two...
Establishment of a highly sensitive and specific exon-trapping system.
Hamaguchi, M, Sakamoto, H, Tsuruta, H, Sasaki, H, Muto, T, Sugimura, T, ...
We have established a highly sensitive and specific exon-trapping system (SETS) with a specific plasmid vector in which an exon in a given DNA segment is identified by its ability to remain as a...
Kato, S, Sasaki, H, Suzawa, M, Masushige, S, Tora, L, Chambon, P, ...
We describe here a novel class of cis-acting response elements for retinoid, vitamin D, and estrogen receptors which are widely spaced (10 to 200 bp) direct repeats (DRs) of the canonical 5'-AGGTCA...
Matsuzaki, K, Yoshitake, Y, Matuo, Y, Sasaki, H, Nishikawa, K
Two monoclonal antibodies (mAbs) against bovine heparin-binding growth factor II (HBGF-II)/basic fibroblast growth factor (bFGF) were obtained from mouse hybridoma cell lines. They were highly...
A HindIII polymorphism detected by the cDNA encoding amyloid beta protein of Alzheimer's disease.
Sasaki, H, Oishi, N, Furuya, H, Yoshioka, K, Yamada, T, Ogawa, S, ...
Specific DNA binding of the two chicken Deformed family homeodomain proteins, Chox-1.4 and Chox-a.
Sasaki, H, Yokoyama, E, Kuroiwa, A
The cDNA clones encoding two chicken Deformed (Dfd) family homeobox containing genes Chox-1.4 and Chox-a were isolated. Comparison of their amino acid sequences with another chicken Dfd family...
Activation of an imprinted Igf 2 gene in mouse somatic cell cultures.
Eversole-Cire, P, Ferguson-Smith, A C, Sasaki, H, Brown, K D, Cattanach, B M, Gonzales, F A, ...
The mouse insulin-like growth factor II gene (Igf 2), located on distal chromosome 7, is parentally imprinted such that the paternal allele is expressed while the maternal allele is transcriptionally...
Kaneko-Ishino, T, Kume, T U, Sasaki, H, Obinata, M, Oishi, M
By employing cell fusion between two genetically marked mouse erythroleukemia (MEL) cells in which an artificially introduced c-myc gene had been placed under the control of human metallothionein...
Identification of glucagon in the gastrointestinal tract.
Sasaki, H, Rubalcava, B, Baetens, D, Blazquez, E, Srikant, C B, Orci, L, ...
Gel filtration studies on Bio-Gel P-10 columns of a 50-fold purified porcine duodenal extract revealed a main peak of glucagon-like immunoreactivity (GLI) in the 2,900 mol wt zone and a smaller peak...
Furuya, H, Yoshioka, K, Sasaki, H, Sakaki, Y, Nakazato, M, Matsuo, H, ...
A Japanese family with atypical type I familial amyloidotic polyneuropathy (FAP) in Iiyama, Japan was studied. Most of the family members have dysfunctions in the central nervous system, in addition...
Sakai, T, Komuro, H, Katoh, Y, Sasaki, H, Momose-Sato, Y, Kamino, K
1. Employing an optical method for multiple-site simultaneous recording of electrical activity, we have determined the conduction velocity in cervical vagus nerve bundles isolated from 5- to...
Ancestral Origins of the Machado-Joseph Disease Mutation: A Worldwide Haplotype Study
Gaspar, C., Lopes-Cendes, I., Hayes, S., Goto, J., Arvidsson, K., Dias, A., ...
Machado-Joseph disease (MJD) is an autosomal dominant neurodegenerative disorder originally described in families of Portuguese-Azorean ancestry. The cloning of the MJD1 gene allowed identification...
Restricted expression of cell adhesion kinase-beta in rat tissues.
Mitaka, T., Shindoh, M., Mochizuki, Y., Sasaki, H., Ishino, M., Matsuya, M., ...
Cell adhesion kinase-beta (CAK-beta) is a protein tyrosine kinase of the focal adhesion kinase subfamily, which contains large amino- and carboxyl-terminal domains. We studied the tissue distribution...
Increased susceptibility to airway responses in CD40-deficient mice
TAKAHASHI, H, EBIHARA, S, KANDA, A, KAMANAKA, M, SATO, T, HABU, S, ...
The interaction between CD40 and its ligand (CD154) is crucial for IL-12 production and effective humoral immunity such as IgE production. Although the interaction seems to play a crucial role in...
Pulmonary tuberculosis and serum IgE
Ohrui, T, Zayasu, K, Sato, E, Matsui, T, Sekizawa, K, Sasaki, H
Several recent studies indicate that mycobacterium or viral infection may reduce IgE levels or suppress atopy or both. The present study was undertaken to investigate whether Mycobacterium...
Epidemiology of the optic nerve grey crescent in the Reykjavik Eye Study
Jonsson, O, Damji, K F, Jonasson, F, Arnarsson, A, Eysteinsson, T, Sasaki, H, ...
Aim: To establish the epidemiology of the grey crescent in a white population within the age range most susceptible to glaucoma.
The role of cyclic AMP in non-adrenergic non-cholinergic contraction in guinea-pig bronchi.
Aikawa, T., Sekizawa, K., Morikawa, M., Itabashi, S., Sasaki, H., Takishima, T.
1. We investigated the role of adenosine 3':5'-cyclic monophosphate (cyclic AMP) in non-adrenergic non-cholinergic (NANC) contraction in guinea-pig bronchial strips. 2. Forskolin (3 nM to 1 microM)...
Pinto, A., Sekizawa, K., Yamaya, M., Ohrui, T., Jia, Y. X., Sasaki, H.
1. The airway and pulmonary vascular effects of adrenomedullin were studied in the guinea-pig isolated trachea, main bronchi and pulmonary artery in vitro and compared to the effects of calcitonin...
Aikawa, T., Sekizawa, K., Itabashi, S., Sasaki, H., Takishima, T.
We have investigated the effect of prostaglandin E1 (PGE1) on non-adrenergic, non-cholinergic (NANC) contraction in guinea-pig bronchial strips. PGE1 (10 nM to 10 microM) did not alter baseline...
The role of nitric oxide in cholinergic neurotransmission in rat trachea.
Sekizawa, K., Fukushima, T., Ikarashi, Y., Maruyama, Y., Sasaki, H.
1. We have investigated the role of nitric oxide (NO) in cholinergic contraction in rat trachea. 2. Methylene blue (10 nM to 30 microM) potentiated cholinergic contraction induced by electrical field...
Effect of inspiratory flow rate on bronchomotor tone in normal and asthmatic subjects.
Hida, W, Arai, M, Shindoh, C, Liu, Y N, Sasaki, H, Takishima, T
The effect of the inspiratory flow rate during deep inspiration on the regulation of bronchomotor tone was studied in nine normal and 22 asthmatic subjects. Changes in bronchial tone were assessed by...
Laryngeal resistance immediately after panting in asthmatic subjects.
Yanai, M, Ohrui, T, Sekizawa, K, Sasaki, H, Takishima, T
The panting manoeuvre may be used during the assessment of airway resistance and in asthmatic patients during bronchial provocation testing or spontaneous asthma. To study whether panting opens the...
Nephropathy and growth hormone deficiency in a patient with mitochondrial tRNA(Leu(UUR)) mutation.
Yorifuji, T, Kawai, M, Momoi, T, Sasaki, H, Furusho, K, Muroi, J, ...
A mitochondrial A 3243 G mutation in the tRNA(Leu(UUR)) gene was first described as a common cause of MELAS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis, and stroke-like...
Yorifuji, T, Muroi, J, Kawai, M, Uematsu, A, Sasaki, H, Momoi, T, ...
We analysed parental origin and X inactivation status of X derived marker (mar(X)) or ring X (r(X)) chromosomes in six Turner syndrome patients. Two of these patients had mental retardation of...
Wakisaka, A, Sasaki, H, Takada, A, Fukazawa, T, Suzuki, Y, Hamada, T, ...
Spinocerebellar ataxia 1 (SCA1) is caused by expansion of an unstable CAG triplet repeat located on the short arm of chromosome 6. Precise mapping has shown a positional relationship to closely...
Erdheim-Chester disease and slowly progressive cerebellar dysfunction.
Fukazawa, T, Tsukishima, E, Sasaki, H, Hamada, K, Hamada, T, Tashiro, K
A 59 year old woman developed pronounced thirst, increased water intake, and increased urinary output followed by slowly progressive cerebellar symptoms. Brain MRI showed abnormal hyperintensity on...
Antineutrophil cytoplasmic antibodies and the optic-spinal form of multiple sclerosis in Japan.
Fukazawa, T, Hamada, T, Kikuchi, S, Sasaki, H, Tashiro, K, Maguchi, S
Hereditary caeruloplasmin deficiency: clinicopathological study of a patient.
Kawanami, T, Kato, T, Daimon, M, Tominaga, M, Sasaki, H, Maeda, K, ...
A 58 year old patient with dementia, oral dyskinesia, and diabetes mellitus is described. He had an undetectable concentration of serum caeruloplasmin, as an autosomal recessive trait. Brain MRI...
Twenty CAG repeats are sufficient to cause the SCA6 phenotype
Komeichi, K., Sasaki, H., Yabe, I., Yamashita, I., Kikuchi, S., Tashiro, K.
Predisposing chromosome for spinocerebellar ataxia type 6 (SCA6) in Japanese
Yabe, I, Sasaki, H, Yamashita, I, Tashiro, K, Takei, A, Suzuki, Y, ...
Spastin gene mutation in Japanese with hereditary spastic paraplegia
Yabe, I, Sasaki, H, Tashiro, K, Matsuura, T, Takegami, T, Satoh, T
Vocal cord abductor paralysis in spinocerebellar ataxia type 1
SHIOJIRI, T, TSUNEMI, T, MATSUNAGA, T, SASAKI, H, YABE, I, TASHIRO, K, ...
A case of acute urinary retention caused by periaqueductal grey lesion
Yaguchi, H, Soma, H, Miyazaki, Y, Tashiro, J, Yabe, I, Kikuchi, S, ...
Tuberculin responses and risk of pneumonia in immobile elderly patients
Nakayama, K., Monma, M., Fukushima, T., Ohrui, T., Sasaki, H.
BACKGROUND—Delayed type hypersensitivity (DTH) response to tuberculin is an important marker of T helper 1 (Th1) mediated acquired immunity against tuberculosis. Depressed DTH responses to...
Relationship between asthma severity and progression of Alzheimer's disease
Ohrui, T, Arai, H, Ichinose, M, Matsui, T, Yamaya, M, Sasaki, H
Increased blood carboxyhaemoglobin concentrations in inflammatory pulmonary diseases
Yasuda, H, Yamaya, M, Yanai, M, Ohrui, T, Sasaki, H
Background: Exhaled carbon monoxide has been reported to increase in inflammatory pulmonary diseases and to be correlated with blood carboxyhaemoglobin (Hb-CO) concentration. A study was undertaken...
Yokota, T, Sasaki, H, Iwabuchi, K, Shiojiri, T, Yoshino, A, Otagiri, A, ...
OBJECTIVES—To characterise electrophysiologically the central motor conduction of spinocerebellar atrophy type 1 (SCA1), type 2 (SCA2), and Machado-Joseph disease (MJD). METHODS—Motor evoked...
Yamada, M, Kubo, H, Ishizawa, K, Kobayashi, S, Shinkawa, M, Sasaki, H
Background: Tissue repair often occurs in organs damaged by various inflammatory diseases including pneumonia. Inflammatory stimuli induce a rapid and massive release of inflammatory cells from the...
CT and MR imagings of single thyroid lobe (thyroid hemiagenesis) with Graves' disease.
Sasaki, H., Futata, T., Ninomiya, H., Higashi, Y., Okumura, M.
Sasaki, H., Tsutsu, N., Asano, T., Yamamoto, T., Kikuchi, M., Okumura, M.
Primary hyperparathyroidism associated with Albright's hereditary osteodystrophy was diagnosed in a 22 year old Japanese woman, the second such case to be reported. Albright's hereditary...
Yasuda, H, Okinaga, S, Yamaya, M, Ohrui, T, Higuchi, M, Shinkawa, M, ...
Prognostic significance of histopathological subtypes in stage I pure yolk sac tumour of the ovary.
Sasaki, H., Furusato, M., Teshima, S., Kiyokawa, T., Tada, A., Aizawa, S., ...
The correlation between histological subtype [endodermal sinus (ES), polyvesicular vitelline (PV), glandular (G) and hepatoid (H) subtypes] and the prognosis of pure yolk sac tumours (YSTs) of the...
Tumour angiogenesis in latent prostatic carcinoma.
Furusato, M., Wakui, S., Sasaki, H., Ito, K., Ushigome, S.
Unrestrained growth of various malignant tumours has been shown to depend upon a critical number of tumour cells which have switched to the angiogenic phenotype. Angiogenic phenotypes were noted in...
Liu, C Q, Sasaki, H, Fahey, M T, Sakamoto, A, Sato, S, Tanaka, T
In 40 patients with TNM stage T1 ovarian clear cell adenocarcinoma, we used nuclear morphometry to study the relations among morphometric variables, clinical prognostic factors and outcome. The...