H. Stanley Kim

X MECHANISMS OF HUMAN PATHOGENESIS Chair: (2008)

Axel Brakhage, Laszlo Kredics, William C. Nierman, C. Kim Nguyen, H. Stanley Kim, Yan Yu, ...

neutrophil attack

Transcriptional Regulation of Chemical Diversity in Aspergillus fumigatus by LaeA (2007)

Robyn M. Perrin, Natalie D. Fedorova, Jin Woo Bok, Robert A. Cramer Jr., Jennifer R. Wortman, H. Stanley Kim, ...

Secondary metabolites, including toxins and melanins, have been implicated as virulence attributes in invasive aspergillosis. Although not definitively proved, this supposition is supported by the...

Genome sequence alterations detected upon passage of Burkholderia malleiATCC 23344 in culture and in mammalian hosts (2006)

Romero, Claudia M, DeShazer, David, Feldblyum, Tamara, Ravel, Jacques, Woods, Donald, Kim, H Stanley, ...

Abstract Background More than 12,000 simple sequence repeats (SSRs) have been identified in the genome of Burkholderia mallei ATCC 23344. As a demonstrated mechanism of phase variation in other...

Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis (2006)

Yu, Yiting, Kim, H Stanley, Chua, Hui, Lin, Chi, Sim, Siew, Lin, Daoxun, ...

Abstract Background The Gram-negative bacterium Burkholderia pseudomallei (Bp) is the causative agent of the human disease melioidosis. To understand the evolutionary mechanisms contributing to Bp...

Bacterial genome adaptation to niches: Divergence of the potential virulence genes in three Burkholderiaspecies of different survival strategies (2005)

Kim, H Stanley, Schell, Mark A, Yu, Yan, Ulrich, Ricky L, Sarria, Saul H, Nierman, William C, ...

Abstract Background Two closely related species Burkholderia mallei (Bm) and Burkholderia pseudomallei (Bp) are serious human health hazards and are potential bio-warfare agents, whereas another...

BioMed Central (2005)

Bmc Genomics, H Stanley Kim, Mark A Schell, Yan Yu, Ricky L Ulrich, Saul H Sarria, ...

Research article Bacterial genome adaptation to niches: Divergence of the potential virulence genes in three Burkholderia species of different survival strategies

Structural flexibility in the Burkholderia mallei genome

Nierman, William C., DeShazer, David, Kim, H. Stanley, Tettelin, Herve, Nelson, Karen E., Feldblyum, Tamara, ...

The complete genome sequence of Burkholderia mallei ATCC 23344 provides insight into this highly infectious bacterium's pathogenicity and evolutionary history. B. mallei, the etiologic agent of...

The Aspergillus fumigatus StuA Protein Governs the Up-Regulation of a Discrete Transcriptional Program during the Acquisition of Developmental CompetenceD⃞

Sheppard, Donald C., Doedt, Thomas, Chiang, Lisa Y., Kim, H. Stanley, Chen, Dan, Nierman, William C., ...

Members of the Asm1p, Phd1p, Sok2p, Efg1p, and StuAp (APSES) family of fungal proteins regulate morphogenesis and virulence in ascomycetes. We cloned the Aspergillus fumigatus APSES gene encoding...

Bacterial genome adaptation to niches: Divergence of the potential virulence genes in three Burkholderia species of different survival strategies

Kim, H Stanley, Schell, Mark A, Yu, Yan, Ulrich, Ricky L, Sarria, Saul H, Nierman, William C, ...

Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis

Yu, Yiting, Kim, H Stanley, Chua, Hui Hoon, Lin, Chi Ho, Sim, Siew Hoon, Lin, Daoxun, ...

Genome sequence alterations detected upon passage of Burkholderia mallei ATCC 23344 in culture and in mammalian hosts

Romero, Claudia M, DeShazer, David, Feldblyum, Tamara, Ravel, Jacques, Woods, Donald, Kim, H Stanley, ...

Structural flexibility in the Burkholderia mallei genome

Nierman, William C., DeShazer, David, Kim, H. Stanley, Tettelin, Herve, Nelson, Karen E., Feldblyum, Tamara, ...

The complete genome sequence of Burkholderia mallei ATCC 23344 provides insight into this highly infectious bacterium's pathogenicity and evolutionary history. B. mallei, the etiologic agent of...

The Aspergillus fumigatus StuA Protein Governs the Up-Regulation of a Discrete Transcriptional Program during the Acquisition of Developmental CompetenceD⃞

Sheppard, Donald C., Doedt, Thomas, Chiang, Lisa Y., Kim, H. Stanley, Chen, Dan, Nierman, William C., ...

Members of the Asm1p, Phd1p, Sok2p, Efg1p, and StuAp (APSES) family of fungal proteins regulate morphogenesis and virulence in ascomycetes. We cloned the Aspergillus fumigatus APSES gene encoding...

Bacterial genome adaptation to niches: Divergence of the potential virulence genes in three Burkholderia species of different survival strategies

Kim, H Stanley, Schell, Mark A, Yu, Yan, Ulrich, Ricky L, Sarria, Saul H, Nierman, William C, ...

Genomic patterns of pathogen evolution revealed by comparison of Burkholderia pseudomallei, the causative agent of melioidosis, to avirulent Burkholderia thailandensis

Yu, Yiting, Kim, H Stanley, Chua, Hui Hoon, Lin, Chi Ho, Sim, Siew Hoon, Lin, Daoxun, ...

Genome sequence alterations detected upon passage of Burkholderia mallei ATCC 23344 in culture and in mammalian hosts

Romero, Claudia M, DeShazer, David, Feldblyum, Tamara, Ravel, Jacques, Woods, Donald, Kim, H Stanley, ...

Transcriptional Regulation of Chemical Diversity in Aspergillus fumigatus by LaeA

Perrin, Robyn M, Fedorova, Natalie D, Bok, Jin Woo, Cramer, Robert A, Wortman, Jennifer R, Kim, H. Stanley, ...

Secondary metabolites, including toxins and melanins, have been implicated as virulence attributes in invasive aspergillosis. Although not definitively proved, this supposition is supported by the...

Genes Differentially Expressed in Conidia and Hyphae of Aspergillus fumigatus upon Exposure to Human Neutrophils

Sugui, Janyce A., Kim, H. Stanley, Zarember, Kol A., Chang, Yun C., Gallin, John I., Nierman, Willian C., ...

Impaired Ribosome Biogenesis Disrupts the Integration between Morphogenesis and Nuclear Duplication during the Germination of Aspergillus fumigatus▿

Bhabhra, Ruchi, Richie, Daryl L., Kim, H. Stanley, Nierman, William C., Fortwendel, Jarrod, Aris, John P., ...

Aspergillus fumigatus is an important opportunistic fungal pathogen that is responsible for high mortality rates in the immunosuppressed population. CgrA, the A. fumigatus ortholog of a Saccharomyces...

Opine-Based Agrobacterium Competitiveness: Dual Expression Control of the Agrocinopine Catabolism (acc) Operon by Agrocinopines and Phosphate Levels ▿ †

Kim, H. Stanley, Yi, Hyojeong, Myung, Jaehee, Piper, Kevin R., Farrand, Stephen K.

Agrobacterium tumefaciens strain C58 can transform plant cells to produce and secrete the sugar-phosphate conjugate opines agrocinopines A and B. The bacterium then moves in response to the opines...

SreA-mediated iron regulation in Aspergillus fumigatus

Schrettl, Markus, Kim, H Stanley, Eisendle, Martin, Kragl, Claudia, Nierman, William C, Heinekamp, Thorsten, ...

Aspergillus fumigatus, the most common airborne fungal pathogen of humans, employs two high-affinity iron uptake systems: iron uptake mediated by the extracellular siderophore triacetylfusarinine C...