H. Takimoto

Publication List Details

Number

13

Co-Authors

Importance of fatty acid substituents of chemically synthesized lipid A-subunit analogs in the expression of immunopharmacological activity.

Kumazawa, Y, Nakatsuka, M, Takimoto, H, Furuya, T, Nagumo, T, Yamamoto, A, ...

The immunopharmacological activities of chemically synthesized lipid A-subunit analogs, 4-O-phosphono-D-glucosamine derivatives carrying different N- and 3-O-linked acyl groups, were investigated....

Enhancement of immunoglobulin G responses in mice against hepatitis B virus surface antigen, influenza virus hemagglutinin vaccine, and tetanus toxoid by 6-O-acylated muramyl dipeptides.

Furuya, T, Kumazawa, Y, Takimoto, H, Nagumo, T, Watanabe, M, Aizawa, C, ...

The adjuvant activity of chemically synthesized 6-O-acylated muramyl dipeptides (MDP) was tested in aqueous form. The activity was assessed by determining immunoglobulin G (IgG) titers in sera of...

Immunopharmacological activities of 2-keto-3-deoxyoctonic acid-(alpha 2----6)-linked 4-O-phosphono-D-glucosamine derivatives carrying N- and 3-O-acyl substituents.

Kumazawa, Y, Matsuura, M, Homma, J Y, Furuya, T, Takimoto, H, Inagaki, K, ...

The immunopharmacological activities of 2-keto-3-deoxyoctonic acid (KDO)-(alpha 2----6)-linked lipid A-subunit analogs, 4-O-phosphono-D-glucosamine derivatives carrying N- and 3-O-acyl substituents,...

Importance of fatty acid substituents of chemically synthesized lipid A-subunit analogs in the expression of immunopharmacological activity.

Kumazawa, Y, Nakatsuka, M, Takimoto, H, Furuya, T, Nagumo, T, Yamamoto, A, ...

The immunopharmacological activities of chemically synthesized lipid A-subunit analogs, 4-O-phosphono-D-glucosamine derivatives carrying different N- and 3-O-linked acyl groups, were investigated....

Enhancement of immunoglobulin G responses in mice against hepatitis B virus surface antigen, influenza virus hemagglutinin vaccine, and tetanus toxoid by 6-O-acylated muramyl dipeptides.

Furuya, T., Kumazawa, Y., Takimoto, H., Nagumo, T., Watanabe, M., Aizawa, C., ...

The adjuvant activity of chemically synthesized 6-O-acylated muramyl dipeptides (MDP) was tested in aqueous form. The activity was assessed by determining immunoglobulin G (IgG) titers in sera of...

Immunopharmacological activities of 2-keto-3-deoxyoctonic acid-(alpha 2----6)-linked 4-O-phosphono-D-glucosamine derivatives carrying N- and 3-O-acyl substituents.

Kumazawa, Y., Matsuura, M., Homma, J. Y., Furuya, T., Takimoto, H., Inagaki, K., ...

The immunopharmacological activities of 2-keto-3-deoxyoctonic acid (KDO)-(alpha 2----6)-linked lipid A-subunit analogs, 4-O-phosphono-D-glucosamine derivatives carrying N- and 3-O-acyl substituents,...

TCR alpha beta+ CD4- CD8- T cells differentiate extrathymically in an lck-independent manner and participate in early response against Listeria monocytogenes infection through interferon-gamma production.

Kadena, T, Matsuzaki, G, Fujise, S, Kishihara, K, Takimoto, H, Sasaki, M, ...

T-cell receptor (TCR) alpha beta+ CD4- CD8- (double-negative; DN) T cells appear in the peritoneal cavity at an early stage of intraperitoneal (i.p.) infection with the intracellular pathogen...

The stage of negative selection in tolerance induction in neonatal mice.

Ando, T, Yoshikai, Y, Matsuzaki, G, Takimoto, H, Nomoto, K

In flow microfluorometry analysis of thymus and lymph node cells of C57BL/6(I-E-,Mlsb) mice rendered neonatally tolerant to (C57BL/6 x AKR/J)F1 (I-E+,Mlsb/a) lymphoid cells, both CD4+ and CD8+ cells...

Persistent infection with Listeria monocytogenes in the kidney induces anti-inflammatory invariant fetal-type γδ T cells

Ikebe, H, Yamada, H, Nomoto, M, Takimoto, H, Nakamura, T, Sonoda, K-H, ...

After intraperitoneal inoculation with Listeria monocytogenes, γδ T cells appear in the peritoneal cavity preceding the appearance of αβ T cells. Such γδ T cells predominantly express T-cell...

Interferon-γ independent formation of pulmonary granuloma in mice by injections with trehalose dimycolate (cord factor), lipoarabinomannan and phosphatidylinositol mannosides isolated from Mycobacterium tuberculosis

Takimoto, H, Maruyama, H, Shimada, K-I, Yakabe, R, Yano, I, Kumazawa, Y

The mechanisms by which pulmonary granuloma formation is caused by administration of mycobacterial glycolipids such as trehalose dimycolate (TDM), lipoarabinomannan (LAM) and phosphatidylinositol...

Retrograde temporal order amnesia resulting from damage to the fornix

Yasuno, F., Hirata, M., Takimoto, H., Taniguchi, M., Nakagawa, Y., Ikejiri, Y., ...

Some amnesic patients show an impairment of temporal order memory that cannot be accounted for by content memory deficits. The performance of an amnesic patient on memory tasks assessing the...

Characterization of CD4– CD8– CD3+ T-cell receptor-αβ+ T cells in murine cytomegalovirus infection

Hossain, M S, Takimoto, H, Ninomiya, T, Yoshida, H, Kishihara, K, Matsuzaki, G, ...

In this study, we have investigated that after the intraperitoneal infection with murine cytomegalovirus (MCMV), the CD3+ CD4– CD8–(double negative; DN) T-cell receptor (TCR)αβ+ T cells...

Vγ1+ γδ T cells play protective roles at an early phase of murine cytomegalovirus infection through production of interferon-γ

Ninomiya, T, Takimoto, H, Matsuzaki, G, Hamano, S, Yoshida, H, Yoshikai, Y, ...

Cytomegalovirus (CMV) causes severe opportunistic infection in immunocompromised hosts. The importance of conventional αβ T cells in protection against CMV infection has been well documented....