H. Tsukamoto

Publication List Details

Period

1991 - 2008

Number

42

Co-Authors

A dose-escalation study of rituximab for treatment of systemic lupus erythematosus and Evans' syndrome: immunological analysis of B cells, T cells and cytokines (2008)

Tamimoto, Y., Horiuchi, T., Tsukamoto, H., Otsuka, J., Mitoma, H., Kimoto, Y., ...

Objective. Accumulating evidence suggests that B-cell depletion therapy by rituximab may be effective for autoimmune disorders. However, an optimal dose of rituximab and a mechanism of its action...

Association of polymorphisms in complement component C3 gene with susceptibility to systemic lupus erythematosus (2008)

Miyagawa, H., Yamai, M., Sakaguchi, D., Kiyohara, C., Tsukamoto, H., Kimoto, Y., ...

Objective. Identification of the genes responsible for systemic lupus erythematosus (SLE). Methods. All the exons and putative promoter regions of 53 candidate genes (TNFRSF6/Fas, TNFSF6/FasL, Fli1,...

Signaling role of intracellular iron in NF-kappa B activation (2003)

Xiong, S.G., She, H.Y., Takeuchi, H., Han, B., Engelhardt, J.F., Barton, C.H., ...

Iron chelators inhibit endotoxin-induced NF-B activation in hepatic macrophages (HMs), suggesting a role for the intracellular chelatable pool of iron in NF-B activation. The present study tested...

A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus (2003)

Koyama, T., Tsukamoto, H., Masumoto, K., Himeji, D., Hayashi, K., Harada, M., ...

Objective. We investigated the association of gene polymorphisms in APRIL, a new member of the TNF family, with systemic lupus erythematosus. Methods. To detect polymorphisms of the human APRIL gene...

A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus (2003)

Koyama, T., Tsukamoto, H., Masumoto, K., Himeji, D., Hayashi, K., Harada, M., ...

Objective. We investigated the association of gene polymorphisms in APRIL, a new member of the TNF family, with systemic lupus erythematosus. Methods. To detect polymorphisms of the human APRIL gene...

A novel polymorphism of the human APRIL gene is associated with systemic lupus erythematosus (2003)

Koyama, T., Tsukamoto, H., Masumoto, K., Himeji, D., Hayashi, K., Harada, M., ...

Objective. We investigated the association of gene polymorphisms in APRIL, a new member of the TNF family, with systemic lupus erythematosus. Methods. To detect polymorphisms of the human APRIL gene...

CISCO: Cooled Infrared Spectrograph and Camera for OHS on the Subaru Telescope (2002)

Motohara, K., Iwamuro, F., Maihara, T., Oya, S., Tsukamoto, H., Imanishi, M., ...

This paper describes a Cooled Infrared Spectrograph and Camera for OHS (CISCO), mounted on the Nasmyth focus of the Subaru telescope. It is primarily designed as a back-end camera of the OH-Airglow...

Plastic Anisotropy of Metal Matrix Composites With Multidirectional Elastic Fibers. (1998)

Wakashima, K., Mori, T., Tsukamoto, H.

This paper concerned mmc in some important way and contained information about, utilized, or discussed these subjects: basic topics:, data, mmc, mmc data materials and material types:, c/al, elastic...

Mean-Field Micromechanics Model and Its Application to the Analysis of Thermomechanical Behaviour of Composite Materials. (1998)

Wakashima, K., Tsukamoto, H.

This overview article is concerned with the mean-field micromechanics model that has been developed by several investigators as a powerful modification of eshelby's theory for the study of the...

Experimental liver cirrhosis induced by alcohol and iron. (1995)

Tsukamoto, H, Horne, W, Kamimura, S, Niemel , O, Parkkila, S, ...

To determine if alcoholic liver fibrogenesis is exacerbated by dietary iron supplementation, carbonyl iron (0.25% wt/vol) was intragastrically infused with or without ethanol to rats for 16 wk....

IMAGING STUDY ON THE MODE OF DEVELOPMENT AND CHANGES IN AVASCULAR NECROSIS OF THE FEMORAL HEAD IN SYSTEMIC LUPUS ERYTHEMATOSUS: LONG-TERM OBSERVATIONS (1994)

NAGASAWA, K., TSUKAMOTO, H., TADA, Y., MAYUMI, T., SATOH, H., ONITSUKA, H., ...

To find out when and how avascular necrosis of the femoral head (ANFH) develops in patients with SLE who are receiving corticosteroids, we carried outa 3-yr prospective study using imaging methods....

Experimental liver cirrhosis induced by alcohol and iron.

Tsukamoto, H, Horne, W, Kamimura, S, Niemelä, O, Parkkila, S, Ylä-Herttuala, S, ...

To determine if alcoholic liver fibrogenesis is exacerbated by dietary iron supplementation, carbonyl iron (0.25% wt/vol) was intragastrically infused with or without ethanol to rats for 16 wk....

Differential expression in glioblastoma multiforme and cerebral hemangioblastoma of cytoplasmic proteins that bind two different domains within the 3'-untranslated region of the human glucose transporter 1 (GLUT1) messenger RNA.

Tsukamoto, H, Boado, R J, Pardridge, W M

The glucose transporter 1 (GLUT1) protein is underexpressed in human glioblastoma multiforme and is overexpressed in human cerebral hemangioblastoma. To gain in-sight into possible...

Experimental liver cirrhosis induced by alcohol and iron.

Tsukamoto, H, Horne, W, Kamimura, S, Niemelä, O, Parkkila, S, Ylä-Herttuala, S, ...

To determine if alcoholic liver fibrogenesis is exacerbated by dietary iron supplementation, carbonyl iron (0.25% wt/vol) was intragastrically infused with or without ethanol to rats for 16 wk....

Differential expression in glioblastoma multiforme and cerebral hemangioblastoma of cytoplasmic proteins that bind two different domains within the 3'-untranslated region of the human glucose transporter 1 (GLUT1) messenger RNA.

Tsukamoto, H, Boado, R J, Pardridge, W M

The glucose transporter 1 (GLUT1) protein is underexpressed in human glioblastoma multiforme and is overexpressed in human cerebral hemangioblastoma. To gain in-sight into possible...

Synthesis and regulation of the fourth component of complement (C4) in the human monocytic cell line U937: comparison with that of the third component of complement (C3).

Tsukamoto, H, Nagasawa, K, Yoshizawa, S, Tada, Y, Ueda, A, Ueda, Y, ...

Production of the fourth component of complement (C4) by the human monocytic cell line U937 and its regulation were investigated in comparison with the production of the third component of complement...

Effects of cell differentiation on the synthesis of the third and fourth component of complement (C3, C4) by the human monocytic cell line U937.

Tsukamoto, H, Nagasawa, K, Ueda, Y, Mayumi, T, Furugo, I, Tsuru, T, ...

Association of complement synthesis with cell differentiation in U937 cells was investigated using granulocyte-macrophage colony-stimulating factor (GM-CSF), vitamin D3 and interferon-gamma...

Production of the third and fourth component of complement (C3, C4) by smooth muscle cells.

Ueda, Y, Nagasawa, K, Tsukamoto, H, Horiuchi, T, Nishizaka, H, Ikeda, K, ...

Production of the third and fourth components of complement (C3, C4) by smooth muscle cells was investigated by using normal human aortic smooth muscle cells (AoSMC), human smooth muscle cell line...

Liver abnormalities and liver membrane autoantibodies in systemic lupus erythematosus.

Kushimoto, K, Nagasawa, K, Ueda, A, Mayumi, T, Ishii, Y, Yamauchi, Y, ...

The hepatic involvement of 57 patients with systemic lupus erythematosus (SLE) was studied with special reference to liver membrane autoantibody (LMA). Liver abnormalities were found predominantly in...

Potentiation of ethanol-induced pancreatic injury by dietary fat. Induction of chronic pancreatitis by alcohol in rats.

Tsukamoto, H., Towner, S. J., Yu, G. S., French, S. W.

Effects of sustained ethanol intoxication and dietary fat content on pancreatic morphology were investigated in the rat model implanted with gastrostomy catheters, which permitted continuous...

Increased production of the third component of complement (C3) by monocytes from patients with systemic lupus erythematosus.

Tsukamoto, H, Ueda, A, Nagasawa, K, Tada, Y, Niho, Y

We measured in vitro C3 production by peripheral blood monocytes from patients with systemic lupus erythematosus (SLE), and found it to be significantly greater than that from normal controls. We...

Raised serum APRIL levels in patients with systemic lupus erythematosus

Koyama, T, Tsukamoto, H, Miyagi, Y, Himeji, D, Otsuka, J, Miyagawa, H, ...

Methods: Serum samples from 48 patients with SLE, 41 normal healthy subjects, and 21 patients with rheumatoid arthritis (RA) were assayed for APRIL by enzyme linked immunosorbent assay. Medical...

Large-scale culture system of human CD4+ helper/killer T cells for the application to adoptive tumour immunotherapy.

Nakamura, Y., Tokuda, Y., Iwasawa, M., Tsukamoto, H., Kidokoro, M., Kobayashi, N., ...

A simple method for the rapid expansion of human CD4+ T cells with both helper and killer functions was established. CD4+ T cells separated from peripheral blood mononuclear cells using...