MICROWAVE SPECTRA AND DIELECTRIC PROPERTIES OF VARIOUS AZIDES (2002)
Carter, C. P., Watkins, H., Rice, K., Turrell, G. C.
Two silver azide crystals (body centered tetrogonal) were studied. In addition, data were taken on one of these with the cavity in the magnetic field of a fixed magnet. The magnetic field strength,...
Mayosi, B. M., Keavney, B., Kardos, A., Davies, C. H., Ratcliffe, P. J., Farrall, M., ...
Aims Aims: To assess the heritability (i.e. relative contribution of genetic factors to the variability) of continuous measures of left ventricular hypertrophy determined by electrocardiography and...
Hypertrophic cardiomyopathy: from molecular and genetic mechanisms to clinical management (2001)
Molecular genetic research in hypertrophic cardiomyopathy (HCM) has shown that this heart muscle disorder, which was previously considered `idiopathic', is caused by a wide diversity of mutations...
A dinucleotide repeat polymorphism in the MYBPH gene (1994)
Watkins, H., MacRae, C.A., Fischman, D.A., Seidman, J.G., Seidman, C.E.
A dinucleotide repeat polymorphism in the MYBPH gene (1994)
Watkins, H, MacRae, CA, Fischman, DA, Seidman, JG, Seidman, CE
A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2.
Thierfelder, L, MacRae, C, Watkins, H, Tomfohrde, J, Williams, M, McKenna, W, ...
We report that a gene responsible for familial hypertrophic cardiomyopathy (FHC) in a kindred with a mild degree of cardiac hypertrophy maps to chromosome 15q2. The gene encoding cardiac actin,...
Anan, R, Greve, G, Thierfelder, L, Watkins, H, McKenna, W J, Solomon, S, ...
Three novel beta cardiac myosin heavy chain (MHC) gene missense mutations, Phe513Cys, Gly716Arg, and Arg719Trp, which cause familial hypertrophic cardiomyopathy (FHC) are described. One mutation in...
Sporadic hypertrophic cardiomyopathy due to de novo myosin mutations.
Watkins, H, Thierfelder, L, Hwang, D S, McKenna, W, Seidman, J G, Seidman, C E
Hypertrophic cardiomyopathy occurs as an autosomal dominant familial disorder or as a sporadic disease without familial involvement. While missense mutations in the beta cardiac myosin heavy chain...
Watkins, H, Seidman, C E, Seidman, J G, Feng, H S, Sweeney, H L
Mutations in the beta-myosin heavy chain gene are believed to cause hypertrophic cardiomyopathy (HCM) by acting as dominant negative alleles. In contrast, a truncated cardiac troponin T (TnT) that...
Watkins, H, Thierfelder, L, Anan, R, Jarcho, J, Matsumori, A, McKenna, W, ...
The origins of the beta cardiac myosin heavy-chain (MHC) gene missense mutations that cause familial hypertrophic cardiomyopathy (FHC) in 14 families have been evaluated. Of eight different...
A familial hypertrophic cardiomyopathy locus maps to chromosome 15q2.
Thierfelder, L, MacRae, C, Watkins, H, Tomfohrde, J, Williams, M, McKenna, W, ...
We report that a gene responsible for familial hypertrophic cardiomyopathy (FHC) in a kindred with a mild degree of cardiac hypertrophy maps to chromosome 15q2. The gene encoding cardiac actin,...
Anan, R, Greve, G, Thierfelder, L, Watkins, H, McKenna, W J, Solomon, S, ...
Three novel beta cardiac myosin heavy chain (MHC) gene missense mutations, Phe513Cys, Gly716Arg, and Arg719Trp, which cause familial hypertrophic cardiomyopathy (FHC) are described. One mutation in...
Sporadic hypertrophic cardiomyopathy due to de novo myosin mutations.
Watkins, H, Thierfelder, L, Hwang, D S, McKenna, W, Seidman, J G, Seidman, C E
Hypertrophic cardiomyopathy occurs as an autosomal dominant familial disorder or as a sporadic disease without familial involvement. While missense mutations in the beta cardiac myosin heavy chain...
Watkins, H, Seidman, C E, Seidman, J G, Feng, H S, Sweeney, H L
Mutations in the beta-myosin heavy chain gene are believed to cause hypertrophic cardiomyopathy (HCM) by acting as dominant negative alleles. In contrast, a truncated cardiac troponin T (TnT) that...
Watkins, H, Thierfelder, L, Anan, R, Jarcho, J, Matsumori, A, McKenna, W, ...
The origins of the beta cardiac myosin heavy-chain (MHC) gene missense mutations that cause familial hypertrophic cardiomyopathy (FHC) in 14 families have been evaluated. Of eight different...
Jesting Pilate, genetic case–control association studies, and Heart
“What is truth said jesting Pilate….” On truth, F Bacon 1561–1626
Mutations in cis can confound genotype-phenotype correlations in hypertrophic cardiomyopathy
Blair, E., Price, S., Baty, C., Ostman-Smith, I., Watkins, H.
Gaukrodger, N, Mayosi, B, Imrie, H, Avery, P, Baker, M, Connell, J, ...
Background: Rare mutations in the leptin (LEP) gene cause severe obesity. Common polymorphisms of LEP have been associated with obesity, but their association with cardiovascular disease has been...