Machining of nonconductive ZrO2 ceramics with micro-EDM (2009)
Tests were undertaken using micro-EDM drilling with Tungsten Carbide Electrodes and ZrO2 ceramic. A starting layer, in literature often referred to as "assisting electrode" was used to set up a...
A novel approach to efficiency determination in micro electro discharge machining (2008)
The need for high-aspect ratio micro structures in hard to machine materials is constantly growing. Electro-Physical machining processes such as EDM offer distinct advantages to conventional...
Zeidler, J., Mittendorf, T., Vahldiek, G., Zeidler, H., Merkesdal, S.
Objectives. To examine the costs of inpatient and outpatient rehabilitation for musculoskeletal disorders from the perspective of a major statutory health insurance fund in Germany. Methods. A...
Jacobs, J Wg, Boers, M, Boumpas, D, Buttgereit, F, Caeyers, N, ...
OBJECTIVE: To develop evidence based recommendations for the management of systemic glucocorticoid (GC) therapy in rheumatic diseases. METHODS: The multidisciplinary guideline development group from...
Simultaneous registration of dissolved oxygen, Redox potential, hydrogen ion concentration and turbidity in growing bacterial cultures was carried out during the entire duration of culture. The...
Electric discharge machining is a thermally induced manufacturing process which works unaffected by workpiece hardness and toughness and applies nearly no mechanical force to the tool. As it can be...
Study of the energy dependence of the reactions $K^{\pm}$ p -> $K^{0}_{S} \pi^{\pm}$ p (2005)
Delfosse, A, Dorsaz, P, Extermann, P, Gloor, J, Guisan, O, ...
Braun, J., Baraliakos, X., Brandt, J., Listing, J., Zink, A., Alten, R., ...
Objective. Infliximab, a monoclonal antibody against tumour necrosis factor α (TNF-α), is approved in Europe for the treatment of patients with active ankylosing spondylitis (AS) who have responded...
Braun, J., Baraliakos, X., Brandt, J., Listing, J., Zink, A., Alten, R., ...
Objective. Infliximab, a monoclonal antibody against tumour necrosis factor α (TNF-α), is approved in Europe for the treatment of patients with active ankylosing spondylitis (AS) who have responded...
Braun, J., Baraliakos, X., Brandt, J., Listing, J., Zink, A., Alten, R., ...
Objective. Infliximab, a monoclonal antibody against tumour necrosis factor α (TNF-α), is approved in Europe for the treatment of patients with active ankylosing spondylitis (AS) who have responded...
Wagner, A. D., Ju, X. S., Wittkop, U., Peppmüller, M., Zeidler, H., Zenke, M.
Background: Giant cell arteritis (GCA) is a systemic granulomatous vasculitis and characterized by a prompt response to glucocorticoid therapy. Earlier studies demonstrated that dendritic cells (DC)...
Hülsemann, J.L., Hohlfeld, J.M., Schnarr, S., Stoll, M., Zeidler, H.
Infliximab ist ein humanisierender Antikörper gegen Tumor-Nekrose-Faktor [alpha] (TNF alpha] und wird zur Therapie der chronischen Polyarthritis und des M. Crohn eingesetzt. Ca. 200 000 Patienten...
Rapid prototyping of microcomponents and demonstrators in micro system technology (2000)
Fleischer, L., Faust, W., Dost, M., Michel, B., Vogel, J., Zeidler, H.
Clinical relevance of C-reactive protein in axial involvement of ankylosing spondylitis. (1999)
DOUGADOS, M, GUEGUEN, A, NAKACHE, JP, VELICITAT, P, ZEIDLER, H, Veys, Eric, ...
Calin, A., Gueguen, A., Zeidler, H., Mielants, H., Dougados, M.
Objective. Disease activity has been defined using a self-administered instrument, focusing on fatigue, axial pain, peripheral pain, enthesopathy and morning stiffness [Bath Ankylosing Spondylitis...
Brooks, P., Emery, P., Evans, J. F., Fenner, H., Hawkey, C. J., Patrono, C., ...
The International Consensus Meeting on the Mode of Action of COX-2 Inhibition (ICMMAC) brought together 17 international experts in arthritis, gastroenterology and pharmacology on 5–6 December...
Dougados, M, Gueguen, A, Nakache, JP, Velicitat, P, Veys, EM, Zeidler, H, ...
Objective. To consider the re3levance of the duration of a clinical trial in ankylosing spondylitis: long-term (i.e. 1 yr) vs short-term (i.e. 6 weeks) assessment of a non-steroidal anti-inflammatory...
ELEVATED SERUM NITRATE CONCENTRATIONS IN ACTIVE SPONDYLOARTHROPATHIES (1995)
STICHTENOTH, D. O., WOLLENHAUPT, J., ANDERSONE, D., ZEIDLER, H., FRÖLICH, J. C.
We determined the concentrations of nitrate, reflecting endogenous nitric oxide (NO) production, by gas chromatography in the sera of patients with spondyloarthropathy. In those patients with active...
Study of strange bosons decaying into baryon-antibaryon pairs (1990)
Cleland, W E, Delfosse, A, Dorsaz, P A, Extermann, Pierre, Gloor, J L, Guisan, O, ...
Dietl, H., Dobbins, J., Lorenz, E., Mageras, G., Pauss, F., Vogel, H., ...
Dietl, H., Dobbins, J., Lorenz, E., Mageras, G., Pauss, F., Vogel, H., ...
Circulating immune complexes in ankylosing spondylitis (1983)
Deicher, H, Ebringer, A, Hildebrand, S, Kemper, A, Zeidler, H
Persistence of Chlamydia trachomatis Is Induced by Ciprofloxacin and Ofloxacin In Vitro
Dreses-Werringloer, Ute, Padubrin, Ingrid, Jürgens-Saathoff, Barbara, Hudson, Alan P., Zeidler, H., Köhler, L.
An in vitro cell culture model was used to investigate the long-term effect of ciprofloxacin and ofloxacin on infection with Chlamydia trachomatis. Standard in vitro susceptibility testing clearly...
Kuipers, J G, Scharmann, K, Wollenhaupt, J, Nettelnbreker, E, Hopf, S, Zeidler, H
Routine microbiological diagnosis of Chlamydia-induced reactive arthritis is based mainly on the detection of Chlamydia trachomatis with urogenital swabs or in urine. Because chlamydial antigen,...
Persistence of Chlamydia trachomatis Is Induced by Ciprofloxacin and Ofloxacin In Vitro
Dreses-Werringloer, Ute, Padubrin, Ingrid, Jürgens-Saathoff, Barbara, Hudson, Alan P., Zeidler, H., Köhler, L.
An in vitro cell culture model was used to investigate the long-term effect of ciprofloxacin and ofloxacin on infection with Chlamydia trachomatis. Standard in vitro susceptibility testing clearly...
Kuipers, J G, Scharmann, K, Wollenhaupt, J, Nettelnbreker, E, Hopf, S, Zeidler, H
Routine microbiological diagnosis of Chlamydia-induced reactive arthritis is based mainly on the detection of Chlamydia trachomatis with urogenital swabs or in urine. Because chlamydial antigen,...
Stichtenoth, D O, Fauler, J, Zeidler, H, Frölich, J C
OBJECTIVES--To determine daily production of nitric oxide (NO) measured as urinary nitrate excretion, and the effect of prednisolone in patients with rheumatoid arthritis (RA). METHODS--Twenty four...
Hoffmann, J., Herklotz, C., Zeidler, H., Bayer, B., Rosenthal, H., Westermann, J.
OBJECTIVE—The purpose of this study was to investigate the therapeutic potential of the anti-CD2 mAb OX34 first with regard to bone protection in established rat adjuvant arthritis (AA) and...
Kuipers, J., Nietfeld, L., Dreses-Werringloe..., U., Koehler, L., Wollenhaupt, J., Zeidler, H., ...
OBJECTIVE—To optimise sample preparation of synovial fluid for Chlamydia trachomatis (CT) specific polymerase chain reaction (PCR). METHODS—Serial dilutions of purified CT elementary bodies in...
Dougados, M., Combe, B., Cantagrel, A., Goupille, P., Olive, P., Schattenkirchner, M., ...
OBJECTIVES—To investigate the potential clinical benefit of a combination therapy. METHODS—205 patients fulfilling the ACR criteria for rheumatoid arthritis (RA), not treated with disease...
OBJECTIVE—To evaluate the diagnostic performance of classification criteria for rheumatoid arthritis (RA) and reactive arthritis (ReA) in an early synovitis outpatient clinic. METHODS—In a...
Freise, J, Gerard, H, Bunke, T, Whittum-Hudson, J, Zeidler, H, Kohler, L, ...
OBJECTIVE—Molecular biology techniques such as polymerase chain reaction (PCR) and ligase chain reaction (LCR) are routinely used in research for detection of C trachomatis DNA in synovial samples,...
Zink, A, Listing, J, Niewerth, M, Zeidler, H
OBJECTIVE—To describe current treatment of patients with rheumatoid arthritis (RA) in German rheumatology. METHODS—Data from the German rheumatological database of 1998, comprising clinical...
Zink, A, Listing, J, Klindworth, C, Zeidler, H
OBJECTIVE—To describe the aims, principles, and content of the German rheumatological database and to present data on patient mix and healthcare provision for the year 1998. METHODS—The German...
Intra-articular co-infection by Borrelia burgdorferi and Chlamydia trachomatis
Putschky, N, Schnarr, S, Wollenhaupt, J, Zeidler, H, Kuipers, J
OBJECTIVE—Chlamydia trachomatis and Borrelia burgdorferi infections are frequently the cause of unexplained oligoarthritis, as shown by identification of bacteria specific DNA in joint material...
Kvien, T, Zeidler, H, Hannonen, P, Wollheim, F, Forre, O, Hafstrom, I, ...
Objective: To compare the three year safety and efficacy of cyclosporin and parenteral gold in the treatment of early, active, severe rheumatoid arthritis (RA), and to study the reversibility of...
Rau, R, Breedveld, F, Kalden, J, Malaise, M, ...
Objectives: To evaluate efficacy, dose response, safety, and tolerability of adalimumab (D2E7) in disease modifying antirheumatic drug (DMARD) refractory patients with longstanding, active rheumatoid...
Ruof, J, Hulsemann, J, Mittendorf, T, Handelmann, S, Von Der Schulenbu..., J M, Zeidler, H, ...
Objective: To develop a systematic set of German cost data in rheumatoid arthritis (RA) based solely on valid healthcare payer's cost data sources.
Woolf, A, Zeidler, H, Haglund, U, Carr, A, Chaussade, S, Cucinotta, D, ...
Objectives: To describe the impact of musculoskeletal pain (MP); to compare management of MP by the population and by primary care physicians; and to identify misconceptions about treatment.
Rihl, M, Baeten, D, Seta, N, Gu, J, De Keyser, F, Veys, E, ...
Objectives: To validate the use of cDNA based microarray on synovial biopsies by analysing the experimental variability due to amplification of RNA, reproducibility of the assay, heterogeneity of the...
HOFFMANN, J C, HERKLOTZ, C, ZEIDLER, H, BAYER, B, WESTERMANN, J
Anti-CD2 MoAbs have previously been shown to induce tolerance and to block B cell differentiation, T cell and monocyte activation. Since these immune functions are important in joint inflammation, we...
Rihl, M, Gu, J, Baeten, D, Marker-Hermann, E, Goodall, J, Gaston, J, ...
Methods: Complementary DNA based microarrays containing the specific sequence of 56 cytokine transcripts were used for screening. Selected genes were confirmed by reverse transcriptase-polymerase...
Wagner, A, Andresen, J, Raum, E, Lotz, J, Zeidler, H, Kuipers, J, ...
Background: Fever of unknown origin (FUO) is a diagnostic challenge. Rheumatologists are often in charge of patients with FUO because the vasculitides, especially, are potential and common causes of...
Two year maintenance of efficacy and safety of infliximab in the treatment of ankylosing spondylitis
Braun, J, Brandt, J, Listing, J, Zink, A, Alten, R, Burmester, G, ...
Objective: To obtain results of the second year extension of an original 3 month randomised, placebo controlled trial (and the 1 year extension study) assessing the use of infliximab, a monoclonal...
HOFFMANN, J C, BAYER, B, ZEIDLER, H
Reduced levels of a soluble form of the adhesion receptor and CD2 ligand CD58 (sCD58) were previously described in RA patients. In order to understand the biological significance of this finding we...
Direct costs related to rheumatoid arthritis: the patient perspective
Hulsemann, J, Mittendorf, T, Merkesdal, S, Zeh, S, Handelmann, S, Von Der Schulenbu..., J- M, ...
Objective: To determine rheumatoid arthritis related out of pocket expenditure (OOPE) in Germany and to disaggregate the total OOPE into contributing cost domains.
Rihl, M, Kruithof, E, Barthel, C, De Keyser, F, Veys, E, Zeidler, H, ...
Objective: To investigate whether expression of the four members of the neurotrophin (NT) family and their four corresponding receptors is related to synovial inflammation in patients with...
Lack of association of mannose binding lectin variant alleles with systemic lupus erythematosus
Momot, T, Ahmadi‐Simab, K, Gause, A, Gross, W L, Gromnica‐Ihle, E, Peter, H H, ...
Persistent infection of Chlamydia in reactive arthritis
Rihl, M, Köhler, L, Klos, A, Zeidler, H
Unravelling the molecular mechanisms