Bozdech, Zbynek, Ginsburg, Hagai
Abstract The general paradigm that emerges from the analysis of the transcriptome of the malaria parasite Plasmodium falciparum is that the expression clusters of genes that code for enzymes engaged...
Antioxidant defense in Plasmodium falciparum– data mining of the transcriptome (2004)
Bozdech, Zbynek, Ginsburg, Hagai
Abstract The intraerythrocytic malaria parasite is under constant oxidative stress originating both from endogenous and exogenous processes. The parasite is endowed with a complete network of enzymes...
This Provisional Pdf, Zbynek Bozdech, Zbynek Bozdech, Hagai Ginsburg, Hagai Ginsburg
The intraerythrocytic malaria parasite is under constant oxidative stress originating both from endogenous and exogenous processes. The parasite is endowed with a complete network of enzymes and...
Bahl, Amit, Brunk, Brian, Crabtree, Jonathan, Fraunholz, Martin J., Gajria, Bindu, Grant, Gregory R., ...
PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates the recently completed P. falciparum genome sequence and...
Fiori, Pier Luigi, Rappelli, Paola, Mirkarimi, S. N., Ginsburg, Hagai, Cappuccinelli, Pietro Antonio, Turrini, Francesco Michelangelo
Oxidatively stressed red blood cells (RBC) and Plasmodium falciparum-infected RBC (PRBC) are avidly phago-cytosed by human peripheral monocytes. Following the ingestion of PRBC the monocytes' ability...
GINSBURG, HAGAI, GINZBURG, B. Z.
Techniques have been developed for continuous recording of electrical potential difference in maize root preparations. In this way the continuous p.d. profile along the lateral axis of the root could...
GINSBURG, HAGAI, GINZBURG, B. Z.
THO influx, 36Cl– influx and efflux and 22Na influx through maize cortex sleeves were assayed under different temperatures ranging from 5 to 40 °C. The highest Q10 and δH values for THO influx...
Potent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum
Tiffert, Teresa, Ginsburg, Hagai, Krugliak, Miriam, Elford, Barry C., Lew, Virgilio L.
The increasing resistance of the malaria parasite Plasmodium falciparum to currently available drugs demands a continuous effort to develop new antimalarial agents. In this quest, the identification...
Antimalarial Activities of Dermaseptin S4 Derivatives
Krugliak, Miriam, Feder, Rina, Zolotarev, Vadim Y., Gaidukov, Leonid, Dagan, Arie, Ginsburg, Hagai, ...
The hemolytic antimicrobial peptide dermaseptin S4 was recently shown to exert antimalarial activity. In this study, we attempted to understand the underlying mechanism(s) and identify derivatives...
In Vitro Antiplasmodium Effects of Dermaseptin S4 Derivatives
Dagan, Arie, Efron, Leah, Gaidukov, Leonid, Mor, Amram, Ginsburg, Hagai
The 13-residue dermaseptin S4 derivative K4S4(1-13)a (P) was previously shown to kill intraerythrocytic malaria parasites through the lysis of the host cells. In this study, we have sought peptides...
PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data
Bahl, Amit, Brunk, Brian, Crabtree, Jonathan, Fraunholz, Martin J., Gajria, Bindu, Grant, Gregory R., ...
PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates the recently completed P. falciparum genome sequence and...
Antioxidant defense in Plasmodium falciparum – data mining of the transcriptome
Bozdech, Zbynek, Ginsburg, Hagai
The intraerythrocytic malaria parasite is under constant oxidative stress originating both from endogenous and exogenous processes. The parasite is endowed with a complete network of enzymes and...
Bozdech, Zbynek, Ginsburg, Hagai
The general paradigm that emerges from the analysis of the transcriptome of the malaria parasite Plasmodium falciparum is that the expression clusters of genes that code for enzymes engaged in the...
Potent antimalarial activity of clotrimazole in in vitro cultures of Plasmodium falciparum
Tiffert, Teresa, Ginsburg, Hagai, Krugliak, Miriam, Elford, Barry C., Lew, Virgilio L.
The increasing resistance of the malaria parasite Plasmodium falciparum to currently available drugs demands a continuous effort to develop new antimalarial agents. In this quest, the identification...
Antimalarial Activities of Dermaseptin S4 Derivatives
Krugliak, Miriam, Feder, Rina, Zolotarev, Vadim Y., Gaidukov, Leonid, Dagan, Arie, Ginsburg, Hagai, ...
The hemolytic antimicrobial peptide dermaseptin S4 was recently shown to exert antimalarial activity. In this study, we attempted to understand the underlying mechanism(s) and identify derivatives...
In Vitro Antiplasmodium Effects of Dermaseptin S4 Derivatives
Dagan, Arie, Efron, Leah, Gaidukov, Leonid, Mor, Amram, Ginsburg, Hagai
The 13-residue dermaseptin S4 derivative K4S4(1-13)a (P) was previously shown to kill intraerythrocytic malaria parasites through the lysis of the host cells. In this study, we have sought peptides...
PlasmoDB: the Plasmodium genome resource. A database integrating experimental and computational data
Bahl, Amit, Brunk, Brian, Crabtree, Jonathan, Fraunholz, Martin J., Gajria, Bindu, Grant, Gregory R., ...
PlasmoDB (http://PlasmoDB.org) is the official database of the Plasmodium falciparum genome sequencing consortium. This resource incorporates the recently completed P. falciparum genome sequence and...
Antioxidant defense in Plasmodium falciparum – data mining of the transcriptome
Bozdech, Zbynek, Ginsburg, Hagai
The intraerythrocytic malaria parasite is under constant oxidative stress originating both from endogenous and exogenous processes. The parasite is endowed with a complete network of enzymes and...
Bozdech, Zbynek, Ginsburg, Hagai
The general paradigm that emerges from the analysis of the transcriptome of the malaria parasite Plasmodium falciparum is that the expression clusters of genes that code for enzymes engaged in the...
Tiffert, Teresa, Lew, Virgilio L., Ginsburg, Hagai, Krugliak, Miriam, Croisille, Laure, Mohandas, Narla
In most inherited red blood cell (RBC) disorders with high gene frequencies in malaria-endemic regions, the distribution of RBC hydration states is much wider than normal. The relationship between...
Bray, Patrick G., Janneh, Omar, Raynes, Kaylene J., Mungthin, Mathirut, Ginsburg, Hagai, Ward, Stephen A.
Here we provide definitive evidence that chloroquine (CQ) uptake in Plasmodium falciparum is determined by binding to ferriprotoporphyrin IX (FPIX). Specific proteinase inhibitors that block the...
The Homeostasis of Plasmodium falciparum-Infected Red Blood Cells
Mauritz, Jakob M. A., Esposito, Alessandro, Ginsburg, Hagai, Kaminski, Clemens F., Tiffert, Teresa, Lew, Virgilio L.
The asexual reproduction cycle of Plasmodium falciparum, the parasite responsible for severe malaria, occurs within red blood cells. A merozoite invades a red cell in the circulation, develops and...
Bozdech, Zbynek, Mok, Sachel, Hu, Guangan, Imwong, Mallika, Jaidee, Anchalee, Russell, Bruce, ...
Plasmodium vivax causes over 100 million clinical infections each year. Primarily because of the lack of a suitable culture system, our understanding of the biology of this parasite lags...