Halina Was

Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice (2008)

Nowis, Dominika, Bugajski, Marek, Winiarska, Magdalena, Bil, Jacek, Szokalska, Angelika, Salwa, Pawel, ...

Abstract Background HO-1 participates in the degradation of heme. Its products can exert unique cytoprotective effects. Numerous tumors express high levels of HO-1 indicating that this enzyme might...

Effects of 15d-PGJ2 on VEGF-induced angiogenic activities and expression of VEGF receptors in endothelial cells

Funovics, Philip, Brostjan, Christine, Nigisch, Anneliese, Fila, Anna, Grochot, Anna, Mleczko, Katarzyna, ...

15-deoxy-12,14Δ-prostaglandin-J2 (15d-PGJ2) upregulates expression of vascular endothelial growth factor (VEGF), but may inhibit angiogenesis. We found that 15d-PGJ2 (1-10 μM) attenuated all...

Overexpression of Heme Oxygenase-1 in Murine Melanoma : Increased Proliferation and Viability of Tumor Cells, Decreased Survival of Mice

Was, Halina, Cichon, Tomasz, Smolarczyk, Ryszard, Rudnicka, Dominika, Stopa, Magdalena, Chevalier, Catherine, ...

Heme oxygenase-1 (HO-1), a cytoprotective enzyme, can be induced in tumors in response to anti-cancer therapies. We investigated the role of HO-1 in B16(F10), S91, and Sk-mel188 melanoma cells....

Stromal cell–derived factor 1 promotes angiogenesis via a heme oxygenase 1–dependent mechanism

Deshane, Jessy, Chen, Sifeng, Caballero, Sergio, Grochot-Przeczek, Anna, Was, Halina, Li Calzi, Sergio, ...

Stromal cell–derived factor 1 (SDF-1) plays a major role in the migration, recruitment, and retention of endothelial progenitor cells to sites of ischemic injury and contributes to...

Zinc protoporphyrin IX, a heme oxygenase-1 inhibitor, demonstrates potent antitumor effects but is unable to potentiate antitumor effects of chemotherapeutics in mice

Nowis, Dominika, Bugajski, Marek, Winiarska, Magdalena, Bil, Jacek, Szokalska, Angelika, Salwa, Pawel, ...

Heme Oxygenase-1 Accelerates Cutaneous Wound Healing in Mice

Grochot-Przeczek, Anna, Lach, Radoslaw, Mis, Jacek, Skrzypek, Klaudia, Gozdecka, Malgorzata, Sroczynska, Patrycja, ...

Heme oxygenase-1 (HO-1), a cytoprotective, pro-angiogenic and anti-inflammatory enzyme, is strongly induced in injured tissues. Our aim was to clarify its role in cutaneous wound healing. In wild...