Han-Cheng Zhang

Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor

Andrade-Gordon, Patricia, Maryanoff, Bruce E., Derian, Claudia K., Zhang, Han-Cheng, Addo, Michael F., Darrow, Andrew L., ...

Protease-activated receptors (PARs) represent a unique family of seven-transmembrane G protein-coupled receptors, which are enzymatically cleaved to expose a truncated extracellular N terminus that...

Design, synthesis, and biological characterization of a peptide-mimetic antagonist for a tethered-ligand receptor

Andrade-Gordon, Patricia, Maryanoff, Bruce E., Derian, Claudia K., Zhang, Han-Cheng, Addo, Michael F., Darrow, Andrew L., ...

Protease-activated receptors (PARs) represent a unique family of seven-transmembrane G protein-coupled receptors, which are enzymatically cleaved to expose a truncated extracellular N terminus that...