Integrative modeling of transcriptional regulation in response to antirheumatic therapy (2009)
Hecker, Michael, Goertsches, Robert, Engelmann, Robby, Thiesen, Hans-Juergen, Guthke, Reinhard
Abstract Background The investigation of gene regulatory networks is an important issue in molecular systems biology and significant progress has been made by combining different types of biological...
SysZNF: the C2H2 zinc finger gene database (2009)
Ding, Guohui, Lorenz, Peter, Kreutzer, Michael, Li, Yixue, Thiesen, Hans-Juergen
C2H2 zinc finger (C2H2-ZNF) genes are one of the largest and most complex gene super-families in metazoan genomes, with hundreds of members in the human and mouse genome. The ongoing investigation of...
Koczan, Dirk, Drynda, Susanne, Hecker, Michael, Drynda, Andreas, Guthke, Reinhard, Kekow, Joern, ...
Abstract Introduction About 30% of rheumatoid arthritis patients fail to respond adequately to TNFα-blocking therapy. There is a medical and socioeconomic need to identify molecular markers for an...
Pfaff, Michael, Woetzel, Dirk, Driesch, Dominik, Toepfer, Susanne, Huber, René, Pohlers, Dirk, ...
Zum Vol. I von: Computer science meets automation: 52. IWK, Internationales Wissenschaftliches Kolloquium ; proceedings ; 10 - 13 September 2007 Zum Vol. II von: Computer science meets automation:...
Perforin deficiency attenuates collagen-induced arthritis (2005)
Bauer, Kristin, Knipper, Annika, Tu-Rapp, Hoang, Koczan, Dirk, Kreutzer, Hans-Jürgen, Nizze, Horst, ...
Abstract Collagen-induced arthritis (CIA), an approved animal model for rheumatoid arthritis, is thought to be a T cell-dependent disease. There is evidence that CD8 + T cells are a major subset...
Mazón Peláez, Ignacio, Vogler, Susanne, Strauss, Ulf, Wernhoff, Patrik, Pahnke, Jens, Brockmann, Gudrun, ...
Experimental autoimmune encephalomyelitis (EAE) is a polygenic chronic inflammatory demyelinating disease of the nervous system, commonly used as an animal model of multiple sclerosis. Previous...
Peláez, Ignacio Mazón, Vogler, Susanne, Strauß, Ulf, Wernhoff, Patrik, Pahnke, Jens, Brockmann, Gudrun, ...
Experimental autoimmune encephalomyelitis (EAE) is a polygenic chronic inflammatory demyelinating disease of the nervous system, commonly used as an animal model of multiple sclerosis. Previous...
Perforin deficiency attenuates collagen-induced arthritis
Bauer, Kristin, Knipper, Annika, Tu-Rapp, Hoang, Koczan, Dirk, Kreutzer, Hans-Jürgen, Nizze, Horst, ...
Collagen-induced arthritis (CIA), an approved animal model for rheumatoid arthritis, is thought to be a T cell-dependent disease. There is evidence that CD8+ T cells are a major subset controlling...
Perforin deficiency attenuates collagen-induced arthritis
Bauer, Kristin, Knipper, Annika, Tu-Rapp, Hoang, Koczan, Dirk, Kreutzer, Hans-Jürgen, Nizze, Horst, ...
Collagen-induced arthritis (CIA), an approved animal model for rheumatoid arthritis, is thought to be a T cell-dependent disease. There is evidence that CD8+ T cells are a major subset controlling...
mtDNA nt13708A Variant Increases the Risk of Multiple Sclerosis
Yu, Xinhua, Koczan, Dirk, Sulonen, Anna-Maija, Akkad, Denis A., Kroner, Antje, Comabella, Manuel, ...
Koczan, Dirk, Drynda, Susanne, Hecker, Michael, Drynda, Andreas, Guthke, Reinhard, Kekow, Joern, ...
Riclet, Raphaël, Chendeb, Mariam, Vonesch, Jean-Luc, Koczan, Dirk, Thiesen, Hans-Juergen, Losson, Régine, ...
Here, we identified the imprinted mesoderm-specific transcript (MEST) gene as an endogenous TIF1β primary target gene and demonstrated that transcriptional intermediary factor (TIF) 1β, through its...
SysZNF: the C2H2 zinc finger gene database
Ding, Guohui, Lorenz, Peter, Kreutzer, Michael, Li, Yixue, Thiesen, Hans-Juergen
C2H2 zinc finger (C2H2-ZNF) genes are one of the largest and most complex gene super-families in metazoan genomes, with hundreds of members in the human and mouse genome. The ongoing investigation of...