Hans-Peter Wirth

Epithelial attachment alters the outcome of Helicobacter pylori infection

Guruge, Janaki L., Falk, Per G., Lorenz, Robin G., Dans, Maria, Wirth, Hans-Peter, Blaser, Martin J., ...

Genetically defined in vivo models are needed to assess the importance of target cell attachment in bacterial pathogenesis. Gastric colonization by Helicobacter pylori in human populations is common...

Experimental Infection of Mongolian Gerbils with Wild-Type and Mutant Helicobacter pylori Strains

Wirth, Hans-Peter, Beins, Michael H., Yang, Manqiao, Tham, Kyi T., Blaser, Martin J.

Experimental Helicobacter pylori infection was studied in Mongolian gerbils with fresh human isolates that carry or do not carry cagA (cagA-positive or cagA-negative, respectively), multiply passaged...

Helicobacter pylori strain-specific differences in genetic content, identified by microarray, influence host inflammatory responses

Israel, Dawn A., Salama, Nina, Arnold, Carrie N., Moss, Steven F., Ando, Takafumi, Wirth, Hans-Peter, ...

Helicobacter pylori enhances the risk for ulcer disease and gastric cancer, yet only a minority of H. pylori–colonized individuals develop disease. We examined the ability of two H. pylori isolates...

Epithelial attachment alters the outcome of Helicobacter pylori infection

Guruge, Janaki L., Falk, Per G., Lorenz, Robin G., Dans, Maria, Wirth, Hans-Peter, Blaser, Martin J., ...

Genetically defined in vivo models are needed to assess the importance of target cell attachment in bacterial pathogenesis. Gastric colonization by Helicobacter pylori in human populations is common...

Experimental Infection of Mongolian Gerbils with Wild-Type and Mutant Helicobacter pylori Strains

Wirth, Hans-Peter, Beins, Michael H., Yang, Manqiao, Tham, Kyi T., Blaser, Martin J.

Experimental Helicobacter pylori infection was studied in Mongolian gerbils with fresh human isolates that carry or do not carry cagA (cagA-positive or cagA-negative, respectively), multiply passaged...

Helicobacter pylori strain-specific differences in genetic content, identified by microarray, influence host inflammatory responses

Israel, Dawn A., Salama, Nina, Arnold, Carrie N., Moss, Steven F., Ando, Takafumi, Wirth, Hans-Peter, ...

Helicobacter pylori enhances the risk for ulcer disease and gastric cancer, yet only a minority of H. pylori–colonized individuals develop disease. We examined the ability of two H. pylori isolates...

Helicobacter pylori Modulates the T Helper Cell 1/T Helper Cell 2 Balance through Phase-variable Interaction between Lipopolysaccharide and DC-SIGN

Bergman, Mathijs P., Engering, Anneke, Smits, Hermelijn H., Van Vliet, Sandra J., Van Bodegraven, Ad A., Wirth, Hans-Peter, ...

The human gastric pathogen Helicobacter pylori spontaneously switches lipopolysaccharide (LPS) Lewis (Le) antigens on and off (phase-variable expression), but the biological significance of this is...