Hans Duimel

Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis (2005)

Losen, Mario, Stassen, Maurice H. W., Martínez-Martínez, Pilar, Machiels, Barbie M., Duimel, Hans, Frederik, Peter, ...

Myasthenia gravis is usually caused by autoantibodies to the acetylcholine receptor (AChR). The AChR is clustered and anchored in the postsynaptic membrane of the neuromuscular junction (NMJ) by a...

Increased expression of rapsyn in muscles prevents acetylcholine receptor loss in experimental autoimmune myasthenia gravis (2005)

Losen, Mario, Stassen, Maurice H. W., Martínez-Martínez, Pilar, Machiels, Barbie M., Duimel, Hans, Frederik, Peter, ...

Myasthenia gravis is usually caused by autoantibodies to the acetylcholine receptor (AChR). The AChR is clustered and anchored in the postsynaptic membrane of the neuromuscular junction (NMJ) by a...

Atrial high energy phosphate content and mitochondrial enzyme activity during chronic atrial fibrillation (2000)

Ausma, Jannie, Coumans, Will A, Duimel, Hans, Van Der Vusse, Ger J, Allessie, Maurits A, Borgers, Marcel

Objective: Prolonged atrial fibrillation (AF) results in (ultra)structural remodelling of atrial cardiomyocytes resembling alterations seen in ischemia-induced ventricular hibernation. The mechanisms...

Overexpression of Rapsyn in Rat Muscle Increases Acetylcholine Receptor Levels in Chronic Experimental Autoimmune Myasthenia Gravis

Martínez-Martínez, Pilar, Losen, Mario, Duimel, Hans, Frederik, Peter, Spaans, Frank, Molenaar, Peter, ...

The primary autoantigen in myasthenia gravis, the acetylcholine receptor (AChR), is clustered and anchored in the postsynaptic membrane of the neuromuscular junction by rapsyn. Previously, we found...

Silencing rapsyn in vivo decreases acetylcholine receptors and augments sodium channels and secondary postsynaptic membrane folding

Martinez-Martinez, Pilar, Phemambucq, Marko, Steinbusch, Laura, Schaeffer, Laurent, Berrih-Aknin, Sonia, Duimel, Hans, ...

The receptor-associated protein of the synapse (rapsyn) is required for anchoring and stabilizing the nicotinic acetylcholine receptor (AChR) in the postsynaptic membrane of the neuromuscular...

Silencing rapsyn in vivo decreases acetylcholine receptors and augments sodium channels and secondary postsynaptic membrane folding

Martinez-Martinez, Pilar, Phemambucq, Marko, Steinbusch, Laura, Schaeffer, Laurent, Berrih-Aknin, Sonia, Duimel, Hans, ...

The receptor-associated protein of the synapse (rapsyn) is required for anchoring and stabilizing the nicotinic acetylcholine receptor (AChR) in the postsynaptic membrane of the neuromuscular...