Hans Scherübl

A novel approach in the treatment of neuroendocrine gastrointestinal tumors: Additive antiproliferative effects of interferon-γ and meta-iodobenzylguanidine (2004)

Höpfner, Michael, Sutter, Andreas P, Huether, Alexander, Ahnert-Hilger, Gudrun, Scherübl, Hans

Abstract Background Therapeutic options to effectively inhibit growth and spread of neuroendocrine gastrointestinal tumors are still limited. As both meta-iodobenzylguanidine (MIBG) and interferon-γ...

Growth factor receptors and related signalling pathways as targets for novel treatment strategies of hepatocellular cancer

Höpfner, Michael, Schuppan, Detlef, Scherübl, Hans

Growth factors and their corresponding receptors are commonly overexpressed and/or dysregulated in many cancers including hepatocellular cancer (HCC). Clinical trials indicate that growth factor...

Treatment of gastrointestinal neuroendocrine tumors with inhibitors of growth factor receptors and their signaling pathways: Recent advances and future perspectives

Höpfner, Michael, Schuppan, Detlef, Scherübl, Hans

The limited efficacy of conventional cytotoxic treatment regimes for advanced gastrointestinal neuroendocrine cancers emphasizes the need for novel and more effective medical treatment options....

Targeted medical therapy of biliary tract cancer: Recent advances and future perspectives

Höpfner, Michael, Schuppan, Detlef, Scherübl, Hans

The limited efficacy of cytotoxic therapy for advanced biliary tract and gallbladder cancers emphasizes the need for novel and more effective medical treatment options. A better understanding of the...