A Self-Learning Fuzzy Discrete Event System for HIV/AIDS Treatment Regimen Selection (2009)
Hao Ying, Senior Member, Senior Member, Rodger D. Macarthur, Jonathan A. Cohn, ...
Syndrome (AIDS) treatment guidelines are modified several times per year to reflect the rapid evolution of the field (e.g., emergence of new antiretroviral drugs). As such, a treatmentdecision...
Detectability of Discrete Event Systems 1 (2009)
Shaolong Shu, Feng Lin, Hao Ying
In this paper, we investigate the detectability problem in discrete event systems. We assume that we do not know initially which state the system is in. The problem is to determine the current and...
A Fuzzy Discrete Event System Approach to Determining Optimal HIV/AIDS Treatment Regimens (2009)
Hao Ying, Senior Member, Rodger D. Macarthur, Jonathan A. Cohn, Hong Ye, ...
Abstract—Treatment decision-making is complex and involves many factors. A systematic decision-making and optimization technology capable of handling variations and uncertainties of patient...
Agents with Fuzzy Recognition-Primed Decision Model (2008)
Hao Ying Professor, Yanqing Ji, Hao Ying, John Yen, Shizhuo Zhu, ...
Discovering unknown adverse drug reactions (ADRs) in postmarketing surveillance as early as possible is highly desirable. Nevertheless, current postmarketing surveillance methods largely rely on...
Kim, Caroline S., Ying, Hao, Willingham, Mark C., Cheng, Sheue-yann
Overexpression of the pituitary tumor-transforming gene (PTTG) has been associated with tumorigenesis. In a mouse model that spontaneously develops follicular thyroid cancer (FTC) with distant...
Hao Ying, Sood Sumita, Triadafilopoulos George, Kim Jong, Wang Zheng, Sahbaie Peyman, ...
Abstract Background Esophageal reflux and Barrett's esophagus represent two major risk factors for the development of esophageal adenocarcinoma. Previous studies have shown that brief exposure of the...
Ying, Hao, Suzuki, Hideyo, Furumoto, Hiroko, Walker, Robert, Meltzer, Paul, Willingham, Mark C., ...
The molecular genetics underlying thyroid carcinogenesis is not well understood. We have recently created a mutant mouse by targeting a mutation (PV) into the thyroid hormone receptor β gene (TRβPV...
Ying, Hao, Suzuki, Hideyo, Furumoto, Hiroko, Walker, Robert, Meltzer, Paul, Willingham, Mark C., ...
The molecular genetics underlying thyroid carcinogenesis is not well understood. We have recently created a mutant mouse by targeting a mutation (PV) into the thyroid hormone receptor β gene (TRβPV...
Ying, Hao, Suzuki, Hideyo, Furumoto, Hiroko, Walker, Robert, Meltzer, Paul, Willingham, Mark C., ...
The molecular genetics underlying thyroid carcinogenesis is not well understood. We have recently created a mutant mouse by targeting a mutation (PV) into the thyroid hormone receptor β gene (TRβPV...
Modeling and control of fuzzy discrete event systems (2002)
Feng Lin, Hao Ying, Senior Member
Abstract—In order to make it possible to effectively represent deterministic uncertainties and vagueness as well as human subjective observation and judgement inherent to many real-world problems...
Fuzzy Control and Modeling : Analytical Foundations and Applications (2000)
A pesar del gran impacto comercial de los sistemas difusos, debido a su lo práctico y poco costoso de sus aplicaciones, su habilidad se basa en que no es necesario conocer los modelos matemáticos...
Chih-Wei Chang, Hao Ying, Gilbert R. Hillman, Brain Mr Images, Thomas A. Kent, John Yen
In this paper, we present a rule-based fuzzy segmentation system that is capable of segmenting magnetic resonance (MR) images of diseased human brains into physiologically and pathologically...
Thesis (Ph. D.)--University of Alabama at Birmingham, 1990.
Furumoto, Hiroko, Ying, Hao, Chandramouli, G. V. R., Zhao, Li, Walker, Robert L., Meltzer, Paul S., ...
Thyroid-stimulating hormone (TSH)-secreting tumors (TSH-omas) are pituitary tumors that constitutively secrete TSH. The molecular genetics underlying this abnormality are not known. We discovered...
Ying, Hao, Furuya, Fumihiko, Willingham, Mark C., Xu, Jianming, O'Malley, Bert W., Cheng, Sheue-yann
Mutations of the thyroid hormone receptor β (TRβ) gene cause resistance to thyroid hormone (RTH). RTH is characterized by increased serum thyroid hormone associated with nonsuppressible...
Araki, Osamu, Ying, Hao, Furuya, Fumihiko, Zhu, Xuguang, Cheng, Sheue-yann
Thyroid hormone (T3) and peroxisome proliferators have overlapping metabolic effects in the maintenance of lipid homeostasis. Their actions are mediated by their respective receptors: thyroid hormone...
Ying, Hao, Furuya, Fumihiko, Zhao, Li, Araki, Osamu, West, Brian L., Hanover, John A., ...
Overexpression of pituitary tumor–transforming 1 (PTTG1) is associated with thyroid cancer. We found elevated PTTG1 levels in the thyroid tumors of a mouse model of follicular thyroid carcinoma...
Furumoto, Hiroko, Ying, Hao, Chandramouli, G. V. R., Zhao, Li, Walker, Robert L., Meltzer, Paul S., ...
Thyroid-stimulating hormone (TSH)-secreting tumors (TSH-omas) are pituitary tumors that constitutively secrete TSH. The molecular genetics underlying this abnormality are not known. We discovered...
Ying, Hao, Furuya, Fumihiko, Willingham, Mark C., Xu, Jianming, O'Malley, Bert W., Cheng, Sheue-yann
Mutations of the thyroid hormone receptor β (TRβ) gene cause resistance to thyroid hormone (RTH). RTH is characterized by increased serum thyroid hormone associated with nonsuppressible...
Araki, Osamu, Ying, Hao, Furuya, Fumihiko, Zhu, Xuguang, Cheng, Sheue-yann
Thyroid hormone (T3) and peroxisome proliferators have overlapping metabolic effects in the maintenance of lipid homeostasis. Their actions are mediated by their respective receptors: thyroid hormone...
Ying, Hao, Furuya, Fumihiko, Zhao, Li, Araki, Osamu, West, Brian L., Hanover, John A., ...
Overexpression of pituitary tumor–transforming 1 (PTTG1) is associated with thyroid cancer. We found elevated PTTG1 levels in the thyroid tumors of a mouse model of follicular thyroid carcinoma...
Rapid nongenomic actions of thyroid hormone
Hiroi, Yukio, Kim, Hyung-Hwan, Ying, Hao, Furuya, Fumihiko, Huang, Zhihong, Simoncini, Tommaso, ...
The binding of thyroid hormone to the thyroid hormone receptor (TR) mediates important physiological effects. However, the transcriptional effects of TR mediated by the thyroid response element (TRE)...
Impaired Adipogenesis Caused by a Mutated Thyroid Hormone α1 Receptor▿
Ying, Hao, Araki, Osamu, Furuya, Fumihiko, Kato, Yasuhito, Cheng, Sheue-Yann
Thyroid hormone (T3) is critical for growth, differentiation, and maintenance of metabolic homeostasis. Mice with a knock-in mutation in the thyroid hormone receptor α gene (TRα1PV) were created...
SMRT repression of nuclear receptors controls the adipogenic set point and metabolic homeostasis
Nofsinger, Russell R., Li, Pingping, Hong, Suk-Hyun, Jonker, Johan W., Barish, Grant D., Ying, Hao, ...
The nuclear receptor corepressor, silencing mediator of retinoid and thyroid hormone receptors (SMRT), is recruited by a plethora of transcription factors to mediate lineage and signal-dependent...