Harold Legg

Purification and Characterization of Oligomeric Envelope Glycoprotein from a Primary R5 Subtype B Human Immunodeficiency Virus

Srivastava, Indresh K., Stamatatos, Leonidas, Legg, Harold, Kan, Elaine, Fong, Anne, Coates, Stephen R., ...

Human immunodeficiency virus (HIV) continues to be a major public health problem throughout the world, with high levels of mortality and morbidity associated with AIDS. Considerable efforts to...

An Alphavirus Replicon Particle Chimera Derived from Venezuelan Equine Encephalitis and Sindbis Viruses Is a Potent Gene-Based Vaccine Delivery Vector

Perri, Silvia, Greer, Catherine E., Thudium, Kent, Doe, Barbara, Legg, Harold, Liu, Hong, ...

Alphavirus replicon particle-based vaccine vectors derived from Sindbis virus (SIN), Semliki Forest virus, and Venezuelan equine encephalitis virus (VEE) have been shown to induce robust...

Characterization of Human Immunodeficiency Virus Gag-Specific Gamma Interferon-Expressing Cells following Protective Mucosal Immunization with Alphavirus Replicon Particles

Gupta, Soumi, Janani, Ramesh, Bin, Qian, Luciw, Paul, Greer, Catherine, Perri, Silvia, ...

A safe, replication-defective viral vector that can induce mucosal and systemic immune responses and confer protection against many infectious pathogens, such as human immunodeficiency virus type 1...

Purification and Characterization of Oligomeric Envelope Glycoprotein from a Primary R5 Subtype B Human Immunodeficiency Virus

Srivastava, Indresh K., Stamatatos, Leonidas, Legg, Harold, Kan, Elaine, Fong, Anne, Coates, Stephen R., ...

Human immunodeficiency virus (HIV) continues to be a major public health problem throughout the world, with high levels of mortality and morbidity associated with AIDS. Considerable efforts to...

An Alphavirus Replicon Particle Chimera Derived from Venezuelan Equine Encephalitis and Sindbis Viruses Is a Potent Gene-Based Vaccine Delivery Vector

Perri, Silvia, Greer, Catherine E., Thudium, Kent, Doe, Barbara, Legg, Harold, Liu, Hong, ...

Alphavirus replicon particle-based vaccine vectors derived from Sindbis virus (SIN), Semliki Forest virus, and Venezuelan equine encephalitis virus (VEE) have been shown to induce robust...

Characterization of Human Immunodeficiency Virus Gag-Specific Gamma Interferon-Expressing Cells following Protective Mucosal Immunization with Alphavirus Replicon Particles

Gupta, Soumi, Janani, Ramesh, Bin, Qian, Luciw, Paul, Greer, Catherine, Perri, Silvia, ...

A safe, replication-defective viral vector that can induce mucosal and systemic immune responses and confer protection against many infectious pathogens, such as human immunodeficiency virus type 1...

β7-integrin-independent enhancement of mucosal and systemic anti-HIV antibody responses following combined mucosal and systemic gene delivery

Goodsell, Amanda, Zhou, Fengmin, Gupta, Soumi, Singh, Manmohan, Malyala, Padma, Kazzaz, Jina, ...

Vaccination strategies that can block or limit heterosexual human immunodeficiency virus (HIV) transmissions to local and systemic tissues are the goal of much research effort. Herein, in a mouse...