Hasan H. Otu

Grammar-based distance in progressive multiple sequence alignment (2008)

Russell, David J, Otu, Hasan H, Sayood, Khalid

Abstract Background We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithms. The...

Gene expression analysis of embryonic stem cells expressing VE-cadherin (CD144) during endothelial differentiation (2008)

Nikolova-Krstevski, Vesna, Bhasin, Manoj, Otu, Hasan H, Libermann, Towia, Oettgen, Peter

Abstract Background Endothelial differentiation occurs during normal vascular development in the developing embryo. This process is recapitulated in the adult when endothelial progenitor cells are...

Grammar-Based Distance in Progressive Multiple Sequence Alignment (2008)

Russell, David, Otu, Hasan H, Sayood, Khalid

Background: We propose a multiple sequence alignment (MSA) algorithm and compare the alignment-quality and execution-time of the proposed algorithm with that of existing algorithms. The proposed...

A new sequence distance measure for phylogenetic tree construction (2003)

Otu, Hasan H., Sayood, Khalid

Motivation: Most existing approaches for phylogenetic inference use multiple alignment of sequences and assume some sort of an evolutionary model. The multiple alignment strategy does not work for...

A divide-and-conquer approach to fragment assembly (2003)

Otu, Hasan H., Sayood, Khalid

Motivation: One of the major problems in DNA sequencing is assembling the fragments obtained by shotgun sequencing. Most existing fragment assembly techniques follow the overlap—layout—consensus...

The transcriptome of human oocytes

Kocabas, Arif Murat, Crosby, Javier, Ross, Pablo J., Otu, Hasan H., Beyhan, Zeki, Can, Handan, ...

The identification of genes and deduced pathways from the mature human oocyte can help us better understand oogenesis, folliculogenesis, fertilization, and embryonic development. Human metaphase II...

Serum proteome profiling detects myelodysplastic syndromes and identifies CXC chemokine ligands 4 and 7 as markers for advanced disease

Aivado, Manuel, Spentzos, Dimitrios, Germing, Ulrich, Alterovitz, Gil, Meng, Xiao-Ying, Grall, Franck, ...

Myelodysplastic syndromes (MDS) are among the most frequent hematologic malignancies. Patients have a short survival and often progress to acute myeloid leukemia. The diagnosis of MDS can be...

Gene Expression of Purified β-Cell Tissue Obtained from Human Pancreas with Laser Capture Microdissection

Marselli, Lorella, Thorne, Jeffrey, Ahn, Yu-Bae, Omer, Abdulkadir, Sgroi, Dennis C., Libermann, Towia, ...

Context: Human β-cell gene profiling is a powerful tool for understanding β-cell biology in normal and pathological conditions. Assessment is complicated when isolated islets are studied because of...