Heather E. Peckham

Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding (2009)

McKernan, Kevin Judd, Peckham, Heather E., Costa, Gina L., McLaughlin, Stephen F., Fu, Yutao, Tsung, Eric F., ...

We describe the genome sequencing of an anonymous individual of African origin using a novel ligation-based sequencing assay that enables a unique form of error correction that improves the raw...

Rapid whole-genome mutational profiling using next-generation sequencing technologies (2008)

Smith, Douglas R., Quinlan, Aaron R., Peckham, Heather E., Makowsky, Kathryn, Tao, Wei, Woolf, Betty, ...

Forward genetic mutational studies, adaptive evolution, and phenotypic screening are powerful tools for creating new variant organisms with desirable traits. However, mutations generated in the...

Stem cell transcriptome profiling via massive-scale mRNA sequencing (2008)

Cloonan, Nicole, Forrest, Alistair R. R., Kolle, Gabriel, Gardiner, Brooke B. A., Faulkner, Geoffrey J., Brown, Mellissa K., ...

We developed a massive-scale RNA sequencing protocol, short quantitative random RNA libraries or SQRL, to survey the complexity, dynamics and sequence content of transcriptomes in a near-complete...

Nucleosome positioning signals in genomic DNA (2007)

Peckham, Heather E., Thurman, Robert E., Fu, Yutao, Stamatoyannopoulos, John A., Noble, William Stafford, Struhl, Kevin, ...

Although histones can form nucleosomes on virtually any genomic sequence, DNA sequences show considerable variability in their binding affinity. We have used DNA sequences of Saccharomyces cerevisiae...

Nucleosome positioning signals in genomic DNA

Peckham, Heather E., Thurman, Robert E., Fu, Yutao, Stamatoyannopoulos, John A., Noble, William Stafford, Struhl, Kevin, ...

Although histones can form nucleosomes on virtually any genomic sequence, DNA sequences show considerable variability in their binding affinity. We have used DNA sequences of Saccharomyces cerevisiae...

Rapid whole-genome mutational profiling using next-generation sequencing technologies

Smith, Douglas R., Quinlan, Aaron R., Peckham, Heather E., Makowsky, Kathryn, Tao, Wei, Woolf, Betty, ...

Forward genetic mutational studies, adaptive evolution, and phenotypic screening are powerful tools for creating new variant organisms with desirable traits. However, mutations generated in the...

Sequence and structural variation in a human genome uncovered by short-read, massively parallel ligation sequencing using two-base encoding

McKernan, Kevin Judd, Peckham, Heather E., Costa, Gina L., McLaughlin, Stephen F., Fu, Yutao, Tsung, Eric F., ...

We describe the genome sequencing of an anonymous individual of African origin using a novel ligation-based sequencing assay that enables a unique form of error correction that improves the raw...