Heidi F. Horton

An essential role in liver development for transcription factor XBP-1 (2000)

Reimold, Andreas M., Etkin, Amit, Clauss, Isabelle, Perkins, Andrew, Friend, Daniel S., Zhang, John, ...

Multiple differences in gene expression in regulatory Vα24JαQ T cells from identical twins discordant for type I diabetes

Wilson, S. Brian, Kent, Sally C., Horton, Heidi F., Hill, Andrew A., Bollyky, Paul L., Hafler, David A., ...

Quantitative and qualitative defects in CD1d-restricted T cells have been demonstrated in human and murine autoimmune diseases. To investigate the transcriptional consequences of T cell receptor...

Rac2, a Hematopoiesis-Specific Rho GTPase, Specifically Regulates Mast Cell Protease Gene Expression in Bone Marrow-Derived Mast Cells

Gu, Yi, Byrne, Michael C., Paranavitana, Nivanka C., Aronow, Bruce, Siefring, Jamie E., D'Souza, Maria, ...

Rho family GTPases activate intracellular kinase cascades to modulate transcription of multiple genes. Previous studies have examined the roles of the ubiquitously expressed Rho GTPase, Rac1, in...

An essential role in liver development for transcription factor XBP-1

Reimold, Andreas M., Etkin, Amit, Clauss, Isabelle, Perkins, Andrew, Friend, Daniel S., Zhang, John, ...

XBP-1 is a CREB/ATF family transcription factor highly expressed in hepatocellular carcinomas. Here we report that XBP-1 is essential for liver growth. Mice lacking XBP-1 displayed hypoplastic fetal...

Multiple differences in gene expression in regulatory Vα24JαQ T cells from identical twins discordant for type I diabetes

Wilson, S. Brian, Kent, Sally C., Horton, Heidi F., Hill, Andrew A., Bollyky, Paul L., Hafler, David A., ...

Quantitative and qualitative defects in CD1d-restricted T cells have been demonstrated in human and murine autoimmune diseases. To investigate the transcriptional consequences of T cell receptor...

Rac2, a Hematopoiesis-Specific Rho GTPase, Specifically Regulates Mast Cell Protease Gene Expression in Bone Marrow-Derived Mast Cells

Gu, Yi, Byrne, Michael C., Paranavitana, Nivanka C., Aronow, Bruce, Siefring, Jamie E., D'Souza, Maria, ...

Rho family GTPases activate intracellular kinase cascades to modulate transcription of multiple genes. Previous studies have examined the roles of the ubiquitously expressed Rho GTPase, Rac1, in...

An essential role in liver development for transcription factor XBP-1

Reimold, Andreas M., Etkin, Amit, Clauss, Isabelle, Perkins, Andrew, Friend, Daniel S., Zhang, John, ...

XBP-1 is a CREB/ATF family transcription factor highly expressed in hepatocellular carcinomas. Here we report that XBP-1 is essential for liver growth. Mice lacking XBP-1 displayed hypoplastic fetal...

Engagement of the Pd-1 Immunoinhibitory Receptor by a Novel B7 Family Member Leads to Negative Regulation of Lymphocyte Activation

Freeman, Gordon J., Long, Andrew J., Iwai, Yoshiko, Bourque, Karen, Chernova, Tatyana, Nishimura, Hiroyuki, ...

PD-1 is an immunoinhibitory receptor expressed by activated T cells, B cells, and myeloid cells. Mice deficient in PD-1 exhibit a breakdown of peripheral tolerance and demonstrate multiple autoimmune...