Heiko Peters

A genome wide analysis of the response to uncapped telomeres in budding yeast reveals a novel role for the NAD+biosynthetic gene BNA2in chromosome end protection (2008)

Greenall, Amanda, Lei, Guiyuan, Swan, Daniel C, James, Katherine, Wang, Liming, Peters, Heiko, ...

Abstract Background Telomeres prevent the ends of eukaryotic chromosomes from being recognized as damaged DNA and protect against cancer and ageing. When telomere structure is perturbed, a...

Haploinsufficiency of the germ cell-specific nuclear RNA binding protein hnRNP G-T prevents functional spermatogenesis in the mouse (2008)

Ehrmann, Ingrid, Dalgliesh, Caroline, Tsaousi, Aikaterini, Paronetto, Maria Paola, Heinrich, Bettina, Kist, Ralf, ...

Human HNRNPGT, encoding the protein hnRNP G-T, is one of several autosomal retrogenes derived from RBMX. It has been suggested that HNRNPGT functionally replaces the sex-linked RBMX and RBMY genes...

Mitochondrial Dysfunction Accounts for the Stochastic Heterogeneity in Telomere-Dependent Senescence (2007)

João F. Passos, Gabriele Saretzki, Shaheda Ahmed, Glyn Nelson, Torsten Richter, Heiko Peters, ...

Aging is an inherently stochastic process, and its hallmark is heterogeneity between organisms, cell types, and clonal populations, even in identical environments. The replicative lifespan of primary...

The role of PI3K/AKT, MAPK/ERK and NF{kappa}{beta} signalling in the maintenance of human embryonic stem cell pluripotency and viability highlighted by transcriptional profiling and functional analysis (2006)

Armstrong, Lyle, Hughes, Owen, Young, Sun, Hyslop, Louise, Stewart, Rebecca, Wappler, Ilka, ...

Understanding the molecular mechanism by which pluripotency is maintained in human embryonic stem cells (hESC) is important for the development of improved methods to derive, culture and...

Reduction of Pax9 gene dosage in an allelic series of mouse mutants causes hypodontia and oligodontia (2005)

Kist, Ralf, Watson, Michelle, Wang, Xiaomeng, Cairns, Paul, Miles, Colin, Reid, Donald J., ...

Missing teeth (hypodontia and oligodontia) are a common developmental abnormality in humans and heterozygous mutations of PAX9 have recently been shown to underlie a number of familial, non-syndromic...

Reduction of Pax9 gene dosage in an allelic series of mouse mutants causes hypodontia and oligodontia (2005)

Kist, Ralf, Watson, Michelle, Wang, Xiaomeng, Cairns, Paul, Miles, Colin, Reid, Donald J., ...

Missing teeth (hypodontia and oligodontia) are a common developmental abnormality in humans and heterozygous mutations of PAX9 have recently been shown to underlie a number of familial, non-syndromic...

Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency

Wilm, Bettina, Dahl, Edgar, Peters, Heiko, Balling, Rudi, Imai, Kenji

The murine paired box-containing gene Pax1 is required for normal development of the vertebral column, the sternum, and the scapula. Previous studies have shown that three natural Pax1 mouse mutants,...

Altered regulation of platelet-derived growth factor receptor-α gene-transcription in vitro by spina bifida-associated mutant Pax1 proteins

Hol, Frans A., Peters, Heiko, Hamel, Ben C. J., Afink, Gijs B., ...

Mouse models show that congenital neural tube defects (NTDs) can occur as a result of mutations in the platelet-derived growth factor receptor-α gene (PDGFRα). Mice heterozygous for the...

Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities

Peters, Heiko, Neubüser, Annette, Kratochwil, Klaus, Balling, Rudi

Pax genes have been shown to play important roles in mammalian development and organogenesis. Pax9, a member of this transcription factor family, is expressed in somites, pharyngeal pouches,...

Targeted disruption of Pax1 defines its null phenotype and proves haploinsufficiency

Wilm, Bettina, Dahl, Edgar, Peters, Heiko, Balling, Rudi, Imai, Kenji

The murine paired box-containing gene Pax1 is required for normal development of the vertebral column, the sternum, and the scapula. Previous studies have shown that three natural Pax1 mouse mutants,...

Altered regulation of platelet-derived growth factor receptor-α gene-transcription in vitro by spina bifida-associated mutant Pax1 proteins

Hol, Frans A., Peters, Heiko, Hamel, Ben C. J., Afink, Gijs B., ...

Mouse models show that congenital neural tube defects (NTDs) can occur as a result of mutations in the platelet-derived growth factor receptor-α gene (PDGFRα). Mice heterozygous for the...

Pax9-deficient mice lack pharyngeal pouch derivatives and teeth and exhibit craniofacial and limb abnormalities

Peters, Heiko, Neubüser, Annette, Kratochwil, Klaus, Balling, Rudi

Pax genes have been shown to play important roles in mammalian development and organogenesis. Pax9, a member of this transcription factor family, is expressed in somites, pharyngeal pouches,...

Mitochondrial Dysfunction Accounts for the Stochastic Heterogeneity in Telomere-Dependent Senescence

Passos, João F, Saretzki, Gabriele, Ahmed, Shaheda, Nelson, Glyn, Richter, Torsten, Peters, Heiko, ...

Aging is an inherently stochastic process, and its hallmark is heterogeneity between organisms, cell types, and clonal populations, even in identical environments. The replicative lifespan of primary...

Assimilation and Cohort Effects for German Immigrants

Sebastian Gundel, Heiko Peters

Demographic change and the rising demand for highly qualified labor in Germany attracts notice to the analysis of immigration. In addition, the pattern of immigration changed markedly during the past...

What Determines the Duration of Stay of Immigrants in Germany? : Evidence from a Longitudinal Duration Analysis

Sebastian Gundel, Heiko Peters

We analyze the return-migration of German immigrants using the latest data of the German Socio- Economic Panel from 1984 to 2006. We conduct a Cox proportional hazard model with years of residence in...

Lohnungleichheit innerhalb und zwischen Bevölkerungsgruppen in Deutschland und den USA

Heiko Peters

In diesem Beitrag wird die Entwicklung der Lohnungleichheit in den USA und Deutschland betrachtet. Für Deutschland wird als Datengrundlage die harmonisierte Version des Sozioökonomischen Panels und...

Theorie optimaler Währungsräume vor dem Hintergrund der EU-Erweiterung

Heiko Peters

The first step towards integration of the ten new member countries of the European Union was their accession. The second step will be their intregration into the European Monetary Union. Here, they...

Development of Wage Inequality for Natives and Immigrants in Germany : Evidence from Quantile Regression and Decomposition

Heiko Peters

To study the development of wage inequality is important for the economic performance as well as for the development of employment. First, I estimate the remuneration to personal characteristics for...

International mobility of jobs--Diversion from Western to Eastern locations?

Jungnickel, Rolf, Keller, Dietmar, Peters, Heiko, Borrmann, Christine

This contribution discusses to what extent the expansion of German firms in Central East European (CEE) leads to FDI diversion from traditional host countries. Diversion is defined as reduction of...

Family Background or the Characteristics of Children : What Determines High School Success in Germany?

Benjamin Balsmeier, Heiko Peters

It is becoming more and more important to be highly skilled in order to integrate successfully into the labor market. Highly skilled workers receive higher wages and face a lower risk of becoming...

What determines the duration of stay of immigrants in Germany?: Evidence from a longitudinal duration analysis

Sebastian Gundel, Heiko Peters

Purpose – Because of the increasing importance of immigration for Germany due to the ageing population and the lack of highly skilled in some industries, the purpose of this paper is to analyse the...

20 Years of German Unification: Evidence on Income Convergence and Heterogeneity

Brück, Tilman, Peters, Heiko

We analyse the convergence and heterogeneity of living standards between East and West Germany since unification. Based on data from the German Socio-Economic Panel (GSOEP), we compare total...

20 Years of German Unification: Evidence on Income Convergence and Heterogeneity

Tilman Brück, Heiko Peters

We analyse the convergence and heterogeneity of living standards between East and West Germany since unification. Based on data from the German Socio-Economic Panel (GSOEP), we compare total...

20 Years of German Unification: Evidence on Income Convergence and Heterogeneity

Tilman Brück, Heiko Peters

We analyse the convergence and heterogeneity of living standards between East and West Germany since unification. Based on data from the German Socio-Economic Panel (GSOEP), we compare total...