Heinz Bönisch

First evidence for an association of a functional variant in the microRNA-510 target site of the serotonin receptor-type 3E gene with diarrhea predominant irritable bowel syndrome (2008)

Kapeller, Johannes, Houghton, Lesley A., Mönnikes, Hubert, Walstab, Jutta, Möller, Dorothee, Bönisch, Heinz, ...

Diarrhea predominant irritable bowel syndrome (IBS-D) is a complex disorder related to dysfunctions in the serotonergic system. As cis-regulatory variants can play a role in the etiology of complex...

chi-Conopeptide MrIA partially overlaps desipramine and cocaine binding sites on the human norepinephrine transporter (2003)

Heinz Bönisch, Richard J. Lewis

Conotoxins are highly structured proteins that are valuable tools for defining the architecture of membrane-bound proteins, in this case the noradrenaline transporter (NET). This paper provides...

chi-Conopeptide MrIA partially overlaps desipramine and cocaine binding sites on the human norepinephrine transporter (2003)

Heinz Bönisch, Richard J. Lewis

Conotoxins are highly structured proteins that are valuable tools for defining the architecture of membrane-bound proteins, in this case the noradrenaline transporter (NET). This paper provides...

Pharmacological properties of the naturally occurring Ala457 Pro variant of the human norepinephrine transporter (2002)

Filip A. Paczkowski, Heinz Bönisch

This paper reports a detailed analysis of the pharmacological activity of one of the few naturally occurring variants of the human noradrenaline transporter with very low affinity for noradrenaline,...

Pharmacological properties of the naturally occurring Ala457 Pro variant of the human norepinephrine transporter (2002)

Filip A. Paczkowski, Heinz Bönisch

This paper reports a detailed analysis of the pharmacological activity of one of the few naturally occurring variants of the human noradrenaline transporter with very low affinity for noradrenaline,...

Expression and pharmacological profile of the human organic cation transporters hOCT1, hOCT2 and hOCT3

Hayer-Zillgen, Martina, Brüss, Michael, Bönisch, Heinz

Organic cation transporters (OCTs) are involved in the elimination of monoamines and cationic xenobiotics. To examine whether some cell lines express several different OCTs, we investigated seven...