Boekema, Egbert J., Schouten, Stefan, Folea, Mihaela, Schwarz, Heinz, Hobel, Cedric F.V., Pitcher, Angela, ...
The crenarchaea Sulfolobus acidocaldarius, S. solfataricus and S. tokodaii, release membrane vesicles into the medium. These membrane vesicles consist of tetraether lipids and are coated with an...
Ripper, D., Schwarz, Heinz, Stierhof, York-Dieter
BACKGROUND INFORMATION: Electron microscopic immunolabelling of ultrathin thawed cryo-sections, according to the method of Tokuyasu, is widely used as a very sensitive high-resolution localization...
Ulrich, Martina, Petre, Alina, Youhnovski, Nikolay, Prömm, Franziska, Schirle, Markus, Schumm, Michael, ...
Nitration of tyrosine residues has been observed during various acute and chronic inflammatory diseases. However, the mechanism of tyrosine nitration and the nature of the proteins that become...
Moussian, Bernard, Veerkamp, Justus, Müller, Ursula, Schwarz, Heinz
The apical plasma membrane of epithelial cells plays a central role in producing and shaping the apical extracellular matrix (aECM) that eventually adopts a stereotypic architecture required for the...
Plant cytokinesis requires de novo secretory trafficking but not endocytosis. (2007)
Reichardt, I., Stierhof, York-Dieter, Mayer, U., Richter, S., Schwarz, Heinz, Schumacher, K., ...
During plant cytokinesis membrane vesicles are efficiently delivered to the cell-division plane, where they fuse with one another to form a laterally expanding cell plate. These membrane vesicles...
Varmark, H, Llamazares, S, Rebollo, E, Lange, B., Reina, J., Schwarz, Heinz, ...
BACKGROUND: Centrosomes, the major organizers of the microtubule network in most animal cells, are composed of centrioles embedded in a web of pericentriolar material (PCM). Recruitment and...
Correlative light and electron microscopy using immunolabeled resin sections. (2007)
In correlative microscopy, light microscopy provides the overview and orientation in the complex cells and tissue, whereas electron microscopy offers the detailed localization and correlation to...
A comprehensive model for the cellular uptake of cationic cell-penetrating peptides. (2007)
Duchardt, F, Fotin-Mleczek, M., Schwarz, Heinz, Fischer, R, Brock, R.
The plasma membrane represents an impermeable barrier for most macromolecules. Still some proteins and so-called cell-penetrating peptides enter cells efficiently. It has been shown that endocytosis...
Aaron, M., Charbon, G., Lam, H., Schwarz, Heinz, Vollmer, Waldemar, Jacobs-Wagner, C.
The tubulin homologue FtsZ is well known for its essential function in bacterial cell division. Here, we show that in Caulobacter crescentus, FtsZ also plays a major role in cell elongation by...
Drosophila MICAL regulates myofilament organization and synaptic structure. (2007)
Beuchle, Dirk, Schwarz, Heinz, Langegger, Maria, Koch, Iris, Aberle, Hermann
The overall size and structure of a synaptic terminal is an important determinant of its function. In a large-scale mutagenesis screen, designed to identify Drosophila mutants with abnormally...
The vacuolar transporter chaperone (VTC) complex is required for microautophagy. (2007)
Uttenweiler, A., Schwarz, Heinz, Neumann, H., Mayer, A.
Microautophagy involves direct invagination and fission of the vacuolar/lysosomal membrane under nutrient limitation. This occurs by an autophagic tube, a specialized vacuolar membrane invagination...
Varmark, Hanne, Llamazares, Salud, Rebollo, Elena, Lange, Bodo, Reina, Jose, Schwarz, Heinz, ...
Background Centrosomes, the major organizers of the microtubule network in most animal cells, are composed of centrioles embedded in a web of pericentriolar material (PCM). Recruitment and...
Tonning, A, Helms, Sigrun, Schwarz, Heinz, Uv, AE, Moussian, Bernard
Many epithelia produce apical extracellular matrices (aECM) that are crucial for organ morphogenesis or physiology. Apical ECM formation relies on coordinated synthesis and modification of...
Moussian, Bernard, Tang, E., Tonning, A., Helms, Sigrun, Schwarz, Heinz, Nüsslein-Volhard, Christiane, ...
Precise epithelial tube diameters rely on coordinated cell shape changes and apical membrane enlargement during tube growth. Uniform tube expansion in the developing Drosophila trachea requires the...
Cuticle Diffentiation during Drosophila embryogenesis (2006)
Moussian, Bernard, Seifarth, C., Müller, Ursula, Berger, Jürgen, Schwarz, Heinz
Vogt, Nina, Koch, Iris, Schwarz, Heinz, Schnorrer, Frank, Nüsslein-Volhard, Christiane
The gamma-tubulin ring complex (gammaTuRC) forms an essential template for microtubule nucleation in animal cells. The molecular composition of the gammaTuRC has been described; however, the...
Perez Godwyn, P., Peredassadko, A., Schwarz, Heinz, Kastner, Victoria, Gorb, S.
The morphology, ultrastructure, effective elastic modulus, and adhesive properties of two different smooth-type attachment pads were studied in two orthopteran species. Tettigonia viridissima...
Drumea-Mirancea, M., Wessels, J. T., Müller, C. A., Essl, M., Eble, J. A., Tolosa, E., ...
T cells develop in the thymus in a highly specialized cellular and extracellular microenvironment. The basement membrane molecule, laminin-5 (LN-5), is predominantly found in the medulla of the human...
Pogoda, Hans-Martin, Von Der Hardt, Sonja, Herzog, Wiebke, Kramer, C., Schwarz, Heinz, Hammerschmidt, Matthias
Mammalian basic helix-loop-helix proteins of the achaete-scute family are proneural factors that, in addition to the central nervous system, are required for the differentiation of peripheral neurons...
Cheng, K., Koeck, P. J. B., Elmlund, H., Idakieva, K., Parvanova, K., Schwarz, Heinz, ...
Three-dimensional (3D) reconstructions of the two 8.4 MDa Rapana thomasiana hemocyanin isoforms, RtH1 and RtH2, have been obtained by cryoelectron microscopy of molecules embedded in vitreous ice and...
Nica, Gabriella, Herzog, Wiebke, Sonntag, C., Nowak, M., Schwarz, Heinz, Zapata, A. G., ...
The homeodomain transcription factor Six1 and its modulator, the protein phosphatase Eya1, cooperate to promote cell differentiation and survival during mouse organ development. Here, we studied the...
Wietzorrek, A., Schwarz, Heinz, Herrmann, C., Braun, Volkmar
A new Escherichia coli phage, named Rtp, was isolated and shown to be closely related to phage T1. Electron microscopy revealed that phage Rtp has a morphologically unique tail tip consisting of four...
Böttcher, C., Wicky, S., Schwarz, Heinz, Singer-Krüger, B.
Sjl2p is one of three yeast phosphoinositide 5'-phosphatases that belong to the conserved family of synaptojanins. Here, we show that Sjl2p is specifically associated with cortical actin patches...
Cytotoxicity of single-wall carbon nanotubes on human fibroblasts. (2006)
Tian, F., Cui, D., Schwarz, Heinz, Gomez Estrada, G., Kobayashi, H.
We present a toxicological assessment of five carbon nanomaterials on human fibroblast cells in vitro. We correlate the physico-chemical characteristics of these nanomaterials to their toxic effect...
Involvement of chitin in exoskeleton morphogenesis in Drosophila melanogaster. (2005)
Moussian, Bernard, Schwarz, Heinz, Bartoszewski, S., Nusslein-Volhard, Christiane
Exoskeletons stabilize cell, tissue, and body morphology in many living organisms including fungi, plants, and arthropods. In insects, the exoskeleton, the cuticle, is produced by epidermal cells as...
Moussian, Bernard, Soding, Johannes, Schwarz, Heinz, Nusslein-Volhard, Christiane
Mutations in the rtv gene cause disarrangement of chitin fibers in the cuticle of the Drosophila larva, and occasionally the cuticle detaches from the epidermis. We have identified the rtv gene, and...
Grosshans, J., Wenzl, C., Herz, H.M., Bartoszewski, S., Schnorrer, Frank, Vogt, Nina, ...
The physical interaction of the plasma membrane with the associated cortical cytoskeleton is important in many morphogenetic processes during development. At the end of the syncytial blastoderm of...
Seiler, C., Finger-Baier, K.C., Rinner, O., Makhankov, Y.V., Schwarz, Heinz, Neuhauss, S.C., ...
In the sensory receptors of both the eye and the ear, specialized apical structures have evolved to detect environmental stimuli such as light and sound. Despite the morphological divergence of these...
Tunggal, J.A., Helfrich, I., Schmitz, A., Schwarz, Heinz, Gunzel, D., Fromm, M., ...
Cadherin adhesion molecules are key determinants of morphogenesis and tissue architecture. Nevertheless, the molecular mechanisms responsible for the morphogenetic contributions of cadherins remain...
Neuronal migration in the murine rostral migratory stream requires serum response factor. (2005)
Alberti, S., Krause, S.M., Kretz, O., Philippar, U., Lemberger, T., Casanova, E., ...
The central nervous system is fundamentally dependent on guided cell migration, both during development and in adulthood. We report an absolute requirement of the transcription factor serum response...
Sonawane, Mahendra, Carpio, Y., Geisler, Robert, Schwarz, Heinz, Maischein, Hansmartin, Nuesslein-Volhard, Christiane
Epithelial cells are equipped with junctional complexes that are involved in maintaining tissue architecture, providing mechanical integrity and suppressing tumour formation as well as invasiveness....
Schoenthaler, Helia Berit, Lampert, JM, Von Lintig, J, Schwarz, Heinz, Geisler, Robert, Neuhauss, Stephan
Forward genetic screens have been instrumental in defining molecular components of visual function. The zebrafish mutant fading vision (fdv) has been identified in such a screen due to defects in...
Microautophagic vacuole invagination requires calmodulin in a Ca2+-independent function. (2005)
Uttenweiler, A, Schwarz, Heinz, Mayer, A
Microautophagy is the uptake of cytosolic compounds by direct invagination of the vacuolar/lysosomal membrane. In Saccharomyces cerevisiae microautophagic uptake of soluble cytosolic proteins occurs...
Luedeke, C, Frei, SB, Sbalzarini, I, Schwarz, Heinz, Spang, Anne, Barral, Y
Polarized cells frequently use diffusion barriers to separate plasma membrane domains. It is unknown whether diffusion barriers also compartmentalize intracellular organelles. We used photobleaching...
Serratia marcescens internalization and replication in human bladder epithelial cells. (2004)
BACKGROUND: Serratia marcescens, a frequent agent of catheterization-associated bacteriuria, strongly adheres to human bladder epithelial cells in culture. The epithelium normally provides a barrier...
Restricted Mobility of Cell Surface Proteins in the Polar Regions of Escherichia coli. (2004)
DePedro, Miguel, Grunfelder, C. G., Schwarz, Heinz
The polar regions of the Escherichia coli murein sacculus are metabolically inert and stable in time. Because the sacculus and the outer membrane are tightly associated, we investigated whether polar...
Cava, F., DePedro, Miguel, Schwarz, Heinz, Henne, A., Berenguer, J.
Electron microscopy of isolated cell walls of the ancient bacterium Thermus thermophilus revealed that most of the peptidoglycan (PG) surface, apart from the septal region, was shielded against...
Schratt, G., Philippar, U., Hockemeyer, D., Schwarz, Heinz, Alberti, S., Nordheim, A.
The transcription factor serum response factor (SRF) controls the expression of genes involved in cellular proliferation and differentiation. Interestingly, SRF also promotes cell survival by...
Engstler, M., Thilo, L., Weise, F., Grunfelder, C. G., Schwarz, Heinz, Boshard, M., ...
The dense coat of glycosylphosphatidylinositol (GPI)-anchored variant surface glycoprotein (VSG) covering parasitic African trypanosomes is essential for survival in mammalian hosts. VSG is...
Determination of four sequential stages during microautophagy in vitro. (2004)
Kunz, J. B., Schwarz, Heinz, Mayer, A.
Microautophagy is the transfer of cytosolic components into the lysosome by direct invagination of the lysosomal membrane and subsequent budding of vesicles into the lysosomal lumen. This process is...
Söllner, C., Schwarz, Heinz, Geisler, Robert, Nicolson, Teresa
Otoliths in bony fishes and otoconia in mammals are composite crystals consisting of calcium carbonate and proteins. These biominerals are part of the gravity and linear acceleration detection system...
Wicky, S., Schwarz, Heinz, Singer-Kruger, B.
Neo1p is an essential yeast member of the highly conserved Drs2 family of P-type ATPases with proposed aminophospholipid translocase activity. Here we present evidence that Neo1p localizes to...
Control of crystal size and lattice formation by starmaker in otolith biomineralization (2003)
Söllner, Christian, Burghammer, M., Busch-Nentwich, Elisabeth, Berger, Juergen, Schwarz, Heinz, Riekel, C., ...
The stone-like otoliths from the ears of teleost fishes are involved in balance and hearing and consist of calcium carbonate crystallites embedded in a protein framework. We report that a previously...
Efflux-dependent auxin gradients establish the apical-basal axis of Arabidopsis (2003)
Friml, J., Vieten, A., Sauer, M., Weijers, D., Schwarz, Heinz, Hamann, T., ...
Axis formation occurs in plants, as in animals, during early embryogenesis. However, the underlying mechanism is not known. Here we show that the first manifestation of the apical-basal axis in...
Grünfelder, C. G., Engstler, M., Weise, F., Schwarz, Heinz, Stierhof, York Dieter, Morgan, G. W., ...
Recently, proteins linked to glycosylphosphatidylinositol (GPI) residues have received considerable attention both for their association with lipid microdomains and for their specific transport...
Schwab, B., Mathur, J., Saedler, R., Schwarz, Heinz, Frey, B., Scheidegger, C., ...
The control of the directionality of cell expansion was investigated using a class of eight genes, the so-called DISTORTED (DIS) genes, that are required for proper expansion of leaf trichomes in...
Patchiness of murein insertion into the sidewall of Escherichia coli. (2003)
De Pedro, Miguel Angel, Schwarz, Heinz, Koch, A. L.
This paper extends, with computer techniques, the authors' previous work on the kinetics of pole wall and sidewall synthesis in Escherichia coli. These findings extend the conclusion that the nascent...
Sandmann, T., Herrmann, J. M., Dengjel, J., Schwarz, Heinz, Spang, Anne
Protein trafficking is achieved by a bidirectional vesicle flow between the various compartments of the eukaryotic cell. COPII coated vesicles mediate anterograde protein transport from the...
Special issue on high pressure freezing - Foreword (2003)
Hohenberg, H., Müller-Reichert, T., Schwarz, Heinz, Zierold, K.
Steinborn, Katharina, Maulbetsch, Christoph, Priester, Bianca, Trautmann, Susanne, Pacher, Tobias, Geiges, Bernd, ...
Müller, Oliver, Sattler, Tanja, Flötenmeyer, Matthias, Schwarz, Heinz, Plattner, Helmut, Mayer, Andreas
Many intracellular compartments of eukaryotic cells do not adopt a spherical shape, which would be expected in the absence of mechanisms organizing their structure. However, little is known about the...
Koszinowski, Ulrich H., Keil, Günther M., Schwarz, Heinz, Schickedanz, Jörg, Reddehase, Matthias J.
We have constructed target cells by cotransfection of the MHC gene Ld and fragments of murine cytomegalovirus (MCMV) DNA coding for nonstructural immediate-early (IE) proteins. Transfectants were...
Thesis (doctoral)--Universität zu Köln, 1977.
Thesis (doctoral)--Eberhard-Karls-Universität zu Tübingen, 1973.
Stützmomente kreuzweise durchlaufender Rechteckplatten. (1965)
Aus: Dt. Ausschuss f. Stahlbeton. [Veröffentlichungen.] H. 191. - Ursprünglich eingereicht u. d. T.: Berechnung und Konstruktion von Stahlbetonbauten
Thesis (doctoral)--Technische Hochschule Darmstadt, 1962.
The influence of the amber light on starting delay at intersections. (1961)
M.S. (Civil engineering) - Northwestern University, 1961.
Nur Auszug vorhanden
Thesis (doctoral)--München, 1956.
Sulfonamidblutspiegelbestimmungen sowie Literaturübersicht über Vergiftungen bei Ziegen. (1952)
Leipzig, Vet.-med. F., Diss. v. 19. März 1952 (Nicht f. d. Aust.).
Schratt, Gerhard, Weinhold, Birgit, Lundberg, Ante S., Schuck, Sebastian, Berger, Jürgen, Schwarz, Heinz, ...
Addition of serum to mitogen-starved cells activates the cellular immediate-early gene (IEG) response. Serum response factor (SRF) contributes to such mitogen-stimulated transcriptional induction of...
Bormann, Christiane, Baier, Daniel, Hörr, Ingmar, Raps, Claudia, Berger, Jürgen, Jung, Günther, ...
The afp1 gene, which encodes the antifungal protein AFP1, was cloned from nikkomycin-producing Streptomyces tendae Tü901, using a nikkomycin-negative mutant as a host and screening transformants for...
Castán, Pablo, De Pedro, Miguel A., Risco, Cristina, Vallés, Cristina, Fernández, Luis A., Schwarz, Heinz, ...
The role of the 5′ untranslated region (5′UTR) of the S-layer gene from Thermus thermophilus was analyzed through the isolation of Δ5′UTR mutants. In these mutants the half-life of splA mRNA...
De Pedro, Miguel A., Donachie, William D., Höltje, Joachim-Volker, Schwarz, Heinz
The pattern of peptidoglycan (murein) segregation in cells of Escherichia coli with impaired activity of the morphogenetic proteins penicillin-binding protein 2 and RodA has been investigated by the...
Kwok, Terry, Backert, Steffen, Schwarz, Heinz, Berger, Jürgen, Meyer, Thomas F.
Although Helicobacter pylori has generally been considered an extracellular pathogen, a number of in vitro infection experiments and biopsy examinations have shown that it is capable of occasionally...
Jochum, Alexandra, Jackson, David, Schwarz, Heinz, Pipkorn, Rüdiger, Singer-Krüger, Birgit
We previously described the isolation of ysl2-1 due to its genetic interaction with Δypt51/vps21, a mutant with a deletion of the coding sequence for the yeast Rab5 homolog, which regulates...
Branching of Escherichia coli Cells Arises from Multiple Sites of Inert Peptidoglycan†
De Pedro, Miguel A., Young, Kevin D., Höltje, Joachim-Volker, Schwarz, Heinz
Some strains of Escherichia coli defective for dacA, the gene coding for penicillin-binding protein 5, exhibit a strong branching phenotype when cell division is blocked. Since such branch formation...
Heidrich, Christoph, Ursinus, Astrid, Berger, Jürgen, Schwarz, Heinz, Höltje, Joachim-Volker
The multiplicity of murein hydrolases found in most bacteria presents an obstacle to demonstrating the necessity of these potentially autolytic enzymes. Therefore, Escherichia coli mutants with...
Steinborn, Katharina, Maulbetsch, Christoph, Priester, Bianca, Trautmann, Susanne, Pacher, Tobias, Geiges, Bernd, ...
Plant microtubules are organized into specific cell cycle-dependent arrays that have been implicated in diverse cellular processes, including cell division and organized cell expansion. Mutations in...
Grünfelder, Christoph G., Engstler, Markus, Weise, Frank, Schwarz, Heinz, Stierhof, York-Dieter, Morgan, Gareth W., ...
Recently, proteins linked to glycosylphosphatidylinositol (GPI) residues have received considerable attention both for their association with lipid microdomains and for their specific transport...
Sandmann, Thomas, Herrmann, Johannes M., Dengjel, Jörn, Schwarz, Heinz, Spang, Anne
Protein trafficking is achieved by a bidirectional vesicle flow between the various compartments of the eukaryotic cell. COPII coated vesicles mediate anterograde protein transport from the...
Srf–/– ES cells display non-cell-autonomous impairment in mesodermal differentiation
Weinhold, Birgit, Schratt, Gerhard, Arsenian, Sergei, Berger, Jürgen, Kamino, Kenji, Schwarz, Heinz, ...
The serum response factor (SRF) transcription factor is essential for murine embryogenesis. Srf–/– embryos stop developing at the onset of gastrulation, lacking detectable mesoderm. This...
Restricted Mobility of Cell Surface Proteins in the Polar Regions of Escherichia coli
De Pedro, Miguel A., Grünfelder, Christoph G., Schwarz, Heinz
The polar regions of the Escherichia coli murein sacculus are metabolically inert and stable in time. Because the sacculus and the outer membrane are tightly associated, we investigated whether polar...
SRF regulates Bcl-2 expression and promotes cell survival during murine embryonic development
Schratt, Gerhard, Philippar, Ulrike, Hockemeyer, Dirk, Schwarz, Heinz, Alberti, Siegfried, Nordheim, Alfred
The transcription factor serum response factor (SRF) controls the expression of genes involved in cellular proliferation and differentiation. Interestingly, SRF also promotes cell survival by...
Wicky, Sidonie, Schwarz, Heinz, Singer-Krüger, Birgit
Neo1p is an essential yeast member of the highly conserved Drs2 family of P-type ATPases with proposed aminophospholipid translocase activity. Here we present evidence that Neo1p localizes to...
E-cadherin is essential for in vivo epidermal barrier function by regulating tight junctions
Tunggal, Judith A, Helfrich, Iris, Schmitz, Annika, Schwarz, Heinz, Günzel, Dorothee, Fromm, Michael, ...
Cadherin adhesion molecules are key determinants of morphogenesis and tissue architecture. Nevertheless, the molecular mechanisms responsible for the morphogenetic contributions of cadherins remain...
Neuronal migration in the murine rostral migratory stream requires serum response factor
Alberti, Siegfried, Krause, Sven M., Kretz, Oliver, Philippar, Ulrike, Lemberger, Thomas, Casanova, Emilio, ...
The central nervous system is fundamentally dependent on guided cell migration, both during development and in adulthood. We report an absolute requirement of the transcription factor serum response...
Wietzorrek, Andreas, Schwarz, Heinz, Herrmann, Christina, Braun, Volkmar
Anew Escherichia coli phage, named Rtp, was isolated and shown to be closely related to phage T1. Electron microscopy revealed that phage Rtp has a morphologically unique tail tip consisting of four...
The Vacuolar Transporter Chaperone (VTC) Complex Is Required for Microautophagy
Uttenweiler, Andreas, Schwarz, Heinz, Neumann, Heinz, Mayer, Andreas
Microautophagy involves direct invagination and fission of the vacuolar/lysosomal membrane under nutrient limitation. This occurs by an autophagic tube, a specialized vacuolar membrane invagination...
Septin-dependent compartmentalization of the endoplasmic reticulum during yeast polarized growth
Luedeke, Cosima, Frei, Stéphanie Buvelot, Sbalzarini, Ivo, Schwarz, Heinz, Spang, Anne, Barral, Yves
Polarized cells frequently use diffusion barriers to separate plasma membrane domains. It is unknown whether diffusion barriers also compartmentalize intracellular organelles. We used photobleaching...
The Arabidopsis KNOLLE Protein Is a Cytokinesis-specific Syntaxin
Lauber, Martina H., Waizenegger, Irene, Steinmann, Thomas, Schwarz, Heinz, Mayer, Ulrike, Hwang, Inwhan, ...
In higher plant cytokinesis, plasma membrane and cell wall originate by vesicle fusion in the plane of cell division. The Arabidopsis KNOLLE gene, which is required for cytokinesis, encodes a protein...
Wilsch-Bräuninger, Michaela, Schwarz, Heinz, Nüsslein-Volhard, Christiane
Localization of maternally provided RNAs during oogenesis is required for formation of the antero–posterior axis of the Drosophila embryo. Here we describe a subcellular structure in nurse cells...
Oliferenko, Snezhana, Paiha, Karin, Harder, Thomas, Gerke, Volker, Schwärzler, Christoph, Schwarz, Heinz, ...
CD44, the major cell surface receptor for hyaluronic acid (HA), was shown to localize to detergent-resistant cholesterol-rich microdomains, called lipid rafts, in fibroblasts and blood cells. Here,...
Schratt, Gerhard, Philippar, Ulrike, Berger, Jürgen, Schwarz, Heinz, Heidenreich, Olaf, Nordheim, Alfred
The activity of serum response factor (SRF), an essential transcription factor in mouse gastrulation, is regulated by changes in actin dynamics. Using Srf(−/−) embryonic stem (ES) cells, we...
Knaut, Holger, Pelegri, Francisco, Bohmann, Kerstin, Schwarz, Heinz, Nüsslein-Volhard, Christiane
Work in different organisms revealed that the vasa gene product is essential for germline specification. Here, we describe the asymmetric segregation of zebrafish vasa RNA, which distinguishes germ...
Müller, Oliver, Sattler, Tanja, Flötenmeyer, Matthias, Schwarz, Heinz, Plattner, Helmut, Mayer, Andreas
Many intracellular compartments of eukaryotic cells do not adopt a spherical shape, which would be expected in the absence of mechanisms organizing their structure. However, little is known about the...
Structure of the Head of the Bartonella Adhesin BadA
Szczesny, Pawel, Linke, Dirk, Ursinus, Astrid, Bär, Kerstin, Schwarz, Heinz, Riess, Tanja M., ...
Trimeric autotransporter adhesins (TAAs) are a major class of proteins by which pathogenic proteobacteria adhere to their hosts. Prominent examples include Yersinia YadA, Haemophilus Hia and Hsf,...
Harris, Matthew P., Rohner, Nicolas, Schwarz, Heinz, Perathoner, Simon, Konstantinidis, Peter, Nüsslein-Volhard, Christiane
The genetic basis of the development and variation of adult form of vertebrates is not well understood. To address this problem, we performed a mutant screen to identify genes essential for the...
Organotypical tissue cultures from adult murine colon as an in vitro model of intestinal mucosa
Bareiss, Petra M., Metzger, Marco, Sohn, Kai, Rupp, Steffen, Frick, Julia S., Autenrieth, Ingo B., ...
Together with animal experiments, organotypical cell cultures are important models for analyzing cellular interactions of the mucosal epithelium and pathogenic mechanisms in the gastrointestinal...
Analysis of a Novel Insect Cell Culture Medium-Based Growth Medium for Bartonella Species▿
Riess, Tanja, Dietrich, Florian, Schmidt, Katja V., Kaiser, Patrick O., Schwarz, Heinz, Schäfer, Andrea, ...
Human- and animal-pathogenic Bartonella species are fastidious and slow-growing bacteria difficult to isolate and cultivate. We describe a novel, easy-to-prepare liquid medium for the fast and...
Bui, Nhat Khai, Gray, Joe, Schwarz, Heinz, Schumann, Peter, Blanot, Didier, Vollmer, Waldemar
Upon nutrient limitation cells of the swarming soil bacterium Myxococcus xanthus form a multicellular fruiting body in which a fraction of the cells develop into myxospores. Spore development...
Slanchev, Krasimir, Carney, Thomas J., Stemmler, Marc P., Koschorz, Birgit, Amsterdam, Adam, Schwarz, Heinz, ...
The aberrant expression of the transmembrane protein EpCAM is associated with tumor progression, affecting different cellular processes such as cell–cell adhesion, migration, proliferation,...
Cuticle differentiation in the embryo of the amphipod crustacean Parhyale hawaiensis
Havemann, Johanna, Müller, Ursula, Berger, Jürgen, Schwarz, Heinz, Gerberding, Matthias, Moussian, Bernard
The arthropod cuticle is a multilayered extracellular matrix produced by the epidermis during embryogenesis and moulting. Molecularly and histologically, cuticle differentiation has been extensively...
Ulrich, Martina, Petre, Alina, Youhnovski, Nikolay, Prömm, Franziska, Schirle, Markus, Schumm, Michael, ...
Nitration of tyrosine residues has been observed during various acute and chronic inflammatory diseases. However, the mechanism of tyrosine nitration and the nature of the proteins that become...