Stephen Fishbane, Richard Bucala, Brian J G Pereira, Hank Founds, Helen Vlassara
Oishi, Kimihiko, Hofmann, Susanna, Diaz, George A., Brown, Tartania, Manwani, Deepa, Ng, Lily, ...
Thiamin-responsive megaloblastic anemia syndrome (TRMA) is characterized by diabetes mellitus, megaloblastic anemia and sensorineural deafness. Mutations in the thiamin transporter gene SLC19A2 cause...
The role of advanced glycosylation end-products in the pathogenesis of atherosclerosis (1996)
Makita, Zenji, Yanagisawa, Katsuyuki, Kuwajima, Satoru, Bucala, Richard, Vlassara, Helen, Koike, Takao
Coronary artery disease and cerebrovascular disease due to the rapid progression of atherosclerosis is the principal cause of death in diabetes mellitus. Modification of low-density lipoproteins...
Koschinsky, Theodore, He, Ci-Jiang, Mitsuhashi, Tomoko, Bucala, Richard, Liu, Cecilia, Buenting, Christina, ...
Endogenous advanced glycation endproducts (AGEs) include chemically crosslinking species (glycotoxins) that contribute to the vascular and renal complications of diabetes mellitus (DM). Renal...
Tobacco smoke is a source of toxic reactive glycation products
Cerami, Carla, Founds, Hank, Nicholl, Iain, Mitsuhashi, Tomoko, Giordano, Donna, Vanpatten, Sonya, ...
Smokers have a significantly higher risk for developing coronary and cerebrovascular disease than nonsmokers. Advanced glycation end products (AGEs) are reactive, cross-linking moieties that form...
Vlassara, Helen, Cai, Weijing, Crandall, Jill, Goldberg, Teresia, Oberstein, Robert, Dardaine, Veronique, ...
Diet is a major environmental source of proinflammatory AGEs (heat-generated advanced glycation end products); its impact in humans remains unclear. We explored the effects of two equivalent diets,...
Lu, Changyong, He, John Cijiang, Cai, Weijing, Liu, Huixian, Zhu, Li, Vlassara, Helen
Advanced glycation endproducts (AGE) contribute to kidney disease due to diabetes or aging by means of mesangial cell (MC) receptors, such as the receptor for AGE (RAGE), which promote...
Koschinsky, Theodore, He, Ci-Jiang, Mitsuhashi, Tomoko, Bucala, Richard, Liu, Cecilia, Buenting, Christina, ...
Endogenous advanced glycation endproducts (AGEs) include chemically crosslinking species (glycotoxins) that contribute to the vascular and renal complications of diabetes mellitus (DM). Renal...
Tobacco smoke is a source of toxic reactive glycation products
Cerami, Carla, Founds, Hank, Nicholl, Iain, Mitsuhashi, Tomoko, Giordano, Donna, Vanpatten, Sonya, ...
Smokers have a significantly higher risk for developing coronary and cerebrovascular disease than nonsmokers. Advanced glycation end products (AGEs) are reactive, cross-linking moieties that form...
Vlassara, Helen, Cai, Weijing, Crandall, Jill, Goldberg, Teresia, Oberstein, Robert, Dardaine, Veronique, ...
Diet is a major environmental source of proinflammatory AGEs (heat-generated advanced glycation end products); its impact in humans remains unclear. We explored the effects of two equivalent diets,...
Lu, Changyong, He, John Cijiang, Cai, Weijing, Liu, Huixian, Zhu, Li, Vlassara, Helen
Advanced glycation endproducts (AGE) contribute to kidney disease due to diabetes or aging by means of mesangial cell (MC) receptors, such as the receptor for AGE (RAGE), which promote...
Cai, Weijing, He, John C., Zhu, Li, Lu, Changyong, Vlassara, Helen
Advanced glycation end product receptors (AGERs) play distinct functional roles in both the toxicity and disposal of advanced glycation end products (AGEs), substances that are linked to diabetes and...
Reduced Acute Vascular Injury and Atherosclerosis in Hyperlipidemic Mice Transgenic for Lysozyme
Liu, Huixian, Zheng, Feng, Li, Zhu, Uribarri, Jaime, Ren, Bin, Hutter, Randolph, ...
Hyperlipidemia promotes oxidant stress, inflammation, and atherogenesis in apolipoprotein E-deficient (ApoE(−/−)) mice. Mice transgenic for lysozyme (LZ-Tg) are resistant to acute and chronic...
Cai, Weijing, Gao, Qiao-Di, Zhu, Li, Peppa, Melpomeni, He, Cijiang, Vlassara, Helen
BACKGROUND: The general increase in reactive oxygen species generated from glucose-derived advanced glycation endproducts (AGEs) is among the key mechanisms implicated in tissue injury due to...
Cai, Weijing, He, John Cijiang, Zhu, Li, Chen, Xue, Wallenstein, Sylvan, Striker, Gary E., ...
Aging is accompanied by increased oxidative stress (OS) and accumulation of advanced glycation end products (AGEs). AGE formation in food is temperature-regulated, and ingestion of nutrients prepared...
Catera, Rosa, Silverman, Gregg J, Hatzi, Katerina, Seiler, Till, Didier, Sebastien, Zhang, Lu, ...
Chronic lymphocytic leukemia (CLL) represents the outgrowth of a CD5+ B cell. Its etiology is unknown. The structure of membrane Ig on CLL cells of unrelated patients can be remarkably similar....
Cai, Weijing, He, John C., Zhu, Li, Chen, Xue, Zheng, Feng, Striker, Gary E., ...
We previously showed that the content of advanced glycation end products (AGEs) in the diet correlates with serum AGE levels, oxidant stress (OS), organ dysfunction, and lifespan. We now show that...
Linden, Ellena, Cai, Weijing, He, John C., Xue, Chen, Li, Zhu, Winston, Jonathan, ...
Background and objectives: Advanced glycation end products, known pro-inflammatory and pro-oxidative compounds that accumulate in patients with chronic kidney disease, may play a major role in their...