Neuhaus, Jean-Marc, Soppa, Jörg, Wright, J.Keith, Riede, Isolde, Blöcker, Helmut, Frank, Ronand, ...
The cysteine residue at position 148 in the lactose carrier protein of Escherichia coli has been replaced by serine using oligonucleotide-directed, site-specific mutagenesis of the lacY gene. The...
Neuhaus, Jean-Marc, Soppa, Jörg, Wright, J.Keith, Riede, Isolde, Blöcker, Helmut, Frank, Ronand, ...
The cysteine residue at position 148 in the lactose carrier protein of Escherichia coli has been replaced by serine using oligonucleotide-directed, site-specific mutagenesis of the lacY gene. The...
Gross, Roy, Guzman, Carlos A, Sebaihia, Mohammed, Martins Dos Santos, Vítor AP, Pieper, Dietmar H, Koebnik, Ralf, ...
Abstract Background Bordetella petrii is the only environmental species hitherto found among the otherwise host-restricted and pathogenic members of the genus Bordetella . Phylogenetically, it...
BIOINFORMATICS Analysis of disturbed images (2008)
Motivation: Images in cellular and molecular biology (from microscopy, blots, biochips, etc.) are often disturbed, so that the detection and analysis of the respective relevant geometrical objects...
The full-ORF clone resource of the German cDNA Consortium (2007)
Bechtel, Stephanie, Rosenfelder, Heiko, Duda, Anny, Schmidt, Christian, Ernst, Ute, Wellenreuther, Ruth, ...
Abstract Background With the completion of the human genome sequence the functional analysis and characterization of the encoded proteins has become the next urging challenge in the post-genome era....
BMC Genomics Methodology article The full-ORF clone resource of the German cDNA Consortium (2007)
Stephanie Bechtel, Heiko Rosenfelder, Anny Duda, Christian Peter Schmidt, Ute Ernst, Ruth Wellenreuther, ...
© 2007 Bechtel et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License
Complete genome sequence of the myxobacterium Sorangium cellulosum. (2007)
Schneiker, Susanne, Perlova, Olena, Kaiser, Olaf, Gerth, Klaus, Alici, Aysel, Altmeyer, Matthias, ...
FeatureScan: revealing property-dependent similarity of nucleotide sequences (2006)
Igor V. Deyneko, Björn Bredohl, Daniel Wesely, Yulia M. Kalybaeva, Er E. Kel, Helmut Blöcker, ...
FeatureScan is a software package aiming to reveal novel types of DNA sequence similarity by comparing physico-chemical properties. Thirtyeight different parameters of DNA double strands such as...
FeatureScan: revealing property-dependent similarity of nucleotide sequences (2006)
Igor V. Deyneko, Björn Bredohl, Daniel Wesely, Yulia M. Kalybaeva, Er E. Kel, Helmut Blöcker, ...
FeatureScan is a software package aiming to reveal novel types of DNA sequence similarity by comparing physico-chemical properties. Thirtyeight different parameters of DNA double strands such as...
FeatureScan: revealing property-dependent similarity of nucleotide sequences (2006)
Deyneko, Igor V., Bredohl, Björn, Wesely, Daniel, Kalybaeva, Yulia M., Kel, Alexander E., Blöcker, Helmut, ...
FeatureScan is a software package aiming to reveal novel types of DNA sequence similarity by comparing physico-chemical properties. Thirty-eight different parameters of DNA double strands such as...
Analysis of disturbed images (2004)
Kauer, Gerhard, Blöcker, Helmut
Motivation: Images in cellular and molecular biology (from microscopy, blots, biochips etc.) are often disturbed so that the detection and analysis of the respective relevant geometrical objects may...
Analysis of disturbed images (2004)
Kauer, Gerhard, Blöcker, Helmut
Motivation: Images in cellular and molecular biology (from microscopy, blots, biochips, etc.) are often disturbed, so that the detection and analysis of the respective relevant geometrical objects...
Analysis of disturbed images (2004)
Kauer, Gerhard, Blöcker, Helmut
Motivation: Images in cellular and molecular biology (from microscopy, blots, biochips etc.) are often disturbed so that the detection and analysis of the respective relevant geometrical objects may...
Applying signal theory to the analysis of biomolecules (2003)
Kauer, Gerhard, Blöcker, Helmut
Motivation: The accumulation of sequence-related and other biological data for basic research and application purposes invites disaster. It appears very likely that neither traditional thinking nor...
Wiemann, Stefan, Weil, Bernd, Wellenreuther, Ruth, Gassenhuber, Johannes, Glassl, Sabine, Ansorge, Wilhelm, ...
Wiemann, Stefan, Weil, Bernd, Wellenreuther, Ruth, Gassenhuber, Johannes, Glassl, Sabine, Ansorge, Wilhelm, ...
Wiemann, Stefan, Weil, Bernd, Wellenreuther, Ruth, Gassenhuber, Johannes, Glassl, Sabine, Ansorge, Wilhelm, ...
Grafting of discontinuous sites: a protein modeling strategy (1996)
Hornischer, Klaus, Blöcker, Helmut
A strategy for modeling continuous as well as discontinuous sites in protein structures has been developed. Central to this modeling strategy is the search algorithm of FITSITE, a program to search a...
Blöcker, Helmut, Lincoln, David N.
In principle it is most economical to sequence large DNA fragments consecutively (‘primer walking’), provided there is an immediate supply of sequencing primers. To solve the problem of primer...
Heinemann, Udo, Rudolph, Lif-Nicola, Alings, Claudia, Morr, Michael, Heikens, Wiebke, Frank, Ronald, ...
The three-dimensional structure of the self-complementary DNA octamer d(GCCCGpGGC) has been determined in the crystalline state using X-ray diffraction data to a nominal resolution of 2.12 measured...
Collins, John, Szardenings, Michael, Maywald, Friedhelm, Blöcker, Helmut, Frank, Ronald, Hecht, Hans-Jürgen, ...
Edwards, Ulrike, Rogall, Till, Blöcker, Helmut, Emde, Monica, Böttger, Erik C.
Using a set of synthetic oligonucleotides homologous to broadly conserved sequences in-vitro amplification via the polymerase chain reaction followed by direct sequencing results in almost complete...
Complete nucleotide sequence of a 23S ribosomal RNA gene from Micrococcus luteus (1988)
Regensburger, Angela, Ludwig, Wolfgang, Frank, Ronald, Blöcker, Helmut, Schleifer, Karl H.
Crystal structure analysis of an A-DNA fragment at 1.8 A resolution: d(GCCCGGGC) (1987)
Heinemann, Udo, Lauble, Hanspeter, Frank, Ronald, Blöcker, Helmut
Single crystals of the self-complementary octadeoxyribonucleotide d(GCCCGGGC) have been analysed by X-ray diffraction methods at a resolution of 1.8 Å. The tetragonal unit cell of space group P43212...
Fliess, Anja, Wolfes, Heiner, Rosenthal, Andre, Schwellnus, Konrad, Blöcker, Helmut, Frank, Ronald, ...
We have synthesized a series of oligonucleotides containing the EcoRI (GAATTC) or EcoRV (GATATC) recognition site within which or adjacent to which thymidine was substituted by uridine or derivatives...
Atmadja, Johannes, Brimacombe, Richard, Blöcker, Helmut, Frank, Ronald
Intra-RNA cross-links were introduced into E. coli 30S ribosomal subunits by mild ultraviolet irradiation. The subunits were partially digested with cobra venom nuclease, followed in some cases by a...
Rinke, Jutta, Appel, Bernd, Blöcker, Helmut, Frank, Ronald, Lührmann, Reinhard
The 5′-terminal region of U1 snRNA is highly complementary to the consensus exon-intron regions of hnRNA and it has been suggested that U1 snRNP might play a role in the splicing of the pre-mRNA by...
Frank, Ronald, Heikens, Wiebke, Heisterberg-Moutsis, Gudrun, Blöcker, Helmut
A new approach is described which will allow the simultaneous synthesis of large numbers of pre-defined oligonucleotide chains No machine aid is needed. The simultaneous syntheses can be performed by...
Ultrafast sequencing of oligodeoxyribonucleo tides by FAB-mass spectrometry (1982)
Grotjahn, Lutz, Frank, Ronald, Blöcker, Helmut
A fully instrumental method is described for the bidirectional sequencing of oligodeoxyribonucleotides. The methcd makes use of the negative ion fragmentation patterns of fast atom bombardment mass...
Wiemann, Stefan, Weil, Bernd, Wellenreuther, Ruth, Gassenhuber, Johannes, Glassl, Sabine, Ansorge, Wilhelm, ...
With the complete human genomic sequence being unraveled, the focus will shift to gene identification and to the functional analysis of gene products. The generation of a set of cDNAs, both sequences...
Mertens, Gabriele, Hoffmann, Andrea, Blöcker, Helmut, Frank, Ronald, Kahmann, Regine
Inversion of the G segment in bacteriophage Mu DNA occurs by a site-specific recombination event and determines the host specificity of Mu phage particles produced. Inversion is mediated by a Mu...
FeatureScan: revealing property-dependent similarity of nucleotide sequences
Deyneko, Igor V., Bredohl, Björn, Wesely, Daniel, Kalybaeva, Yulia M., Kel, Alexander E., Blöcker, Helmut, ...
FeatureScan is a software package aiming to reveal novel types of DNA sequence similarity by comparing physico-chemical properties. Thirty-eight different parameters of DNA double strands such as...
Wiemann, Stefan, Weil, Bernd, Wellenreuther, Ruth, Gassenhuber, Johannes, Glassl, Sabine, Ansorge, Wilhelm, ...
With the complete human genomic sequence being unraveled, the focus will shift to gene identification and to the functional analysis of gene products. The generation of a set of cDNAs, both sequences...
Mertens, Gabriele, Hoffmann, Andrea, Blöcker, Helmut, Frank, Ronald, Kahmann, Regine
Inversion of the G segment in bacteriophage Mu DNA occurs by a site-specific recombination event and determines the host specificity of Mu phage particles produced. Inversion is mediated by a Mu...
FeatureScan: revealing property-dependent similarity of nucleotide sequences
Deyneko, Igor V., Bredohl, Björn, Wesely, Daniel, Kalybaeva, Yulia M., Kel, Alexander E., Blöcker, Helmut, ...
FeatureScan is a software package aiming to reveal novel types of DNA sequence similarity by comparing physico-chemical properties. Thirty-eight different parameters of DNA double strands such as...