Henrik Ekberg

CTLA4ig induces long-term graft survival of allogeneic skin grafts and totally inhibits T-cell proliferation in LFA-1-deficient mice. (2002)

Malm, Helene, Corbascio, Matthias, Osterholm, Cecilia, Cowan, Shannon, Larsen, Christian P, Pearson, Thomas C, ...

BACKGROUND: It was recently shown that some strains of mice are capable of rejecting transplants independently of B7 and CD40L signaling and that this rejection is mediated by CD8(+) T cells. LFA-1...

Simultaneous inhibition of B7 and LFA-1 signaling prevents rejection of discordant neural xenografts in mice lacking CD40L. (2002)

Larsson, Lena C, Corbascio, Matthias, Widner, Håkan, Pearson, Thomas C, Larsen, Christian P, Ekberg, Henrik

Transplantation of embryonic human neural tissue can restore dopamine neurotransmission and improve neurological function in patients with Parkinson's disease. Logistical and ethical factors limit...

Anti-lymphocyte function-associated antigen-1 monoclonal antibody inhibits CD40 ligand-independent immune responses and prevents chronic vasculopathy in CD40 ligand-deficient mice. (2002)

Corbascio, Matthias, Mahanty, Harish, Osterholm, Cecilia, Qi, Zhongquan, Pearson, Thomas C, Larsen, Christian P, ...

BACKGROUND: Blockade of CD40 ligand (CD40L; CD154, gp39) is a potential treatment for autoimmune disease and allograft rejection. However, CD40L-/- mice are capable of mobilizing cellular immune...

Kidneys from marginal donors: views of patients on informed consent. (2002)

Omnell Persson, Marie, Persson, Nils H, Källén, Ragnar, Ekberg, Henrik, Hermerén, Göran

BACKGROUND:Considering the fact that donor age is a major risk factor for graft survival, and taking into account the importance attached to the principle of autonomy in the Swedish Health Care Law,...

CTLA4Ig combined with anti-LFA-1 prolongs cardiac allograft survival indefinitely. (2002)

Corbascio, Matthias, Ekstrand, Helene, Osterholm, Cecilia, Qi, Zhongquan, Simanaitis, Mecislovas, Larsen, Christian P, ...

CTLA4Ig and anti-LFA-1 are members of a new generation of immunomodulatory drugs which inhibit important signaling pathways in T cell activation. Both substances target molecules which have pivitol...

The Ubiquity and Impressive Genomic Diversity of Human Skin Papillomaviruses Suggest a Commensalic Nature of These Viruses

Antonsson, Annika, Forslund, Ola, Ekberg, Henrik, Sterner, Gunnar, Hansson, Bengt Göran

Human papillomaviruses (HPV) are epitheliotropic viruses, with some types suggested to be associated with skin cancer. In this study, swab samples collected from five different sites on the skin of...

The Ubiquity and Impressive Genomic Diversity of Human Skin Papillomaviruses Suggest a Commensalic Nature of These Viruses

Antonsson, Annika, Forslund, Ola, Ekberg, Henrik, Sterner, Gunnar, Hansson, Bengt Göran

Human papillomaviruses (HPV) are epitheliotropic viruses, with some types suggested to be associated with skin cancer. In this study, swab samples collected from five different sites on the skin of...