Henry K. W. Fong

Gz, a guanine nucleotide-binding protein with unique biochemical properties (1990)

Casey, Patrick J., Fong, Henry K. W., Simon, Melvin I., Gilman, Alfred G.

Cloning of a complementary DNA (cDNA) for Gz alpha, a newly appreciated member of the family of guanine nucleotide-binding regulatory proteins (G proteins), has allowed preparation of specific...

Identification of a GTP-binding protein alpha subunit that lacks an apparent ADP-ribosylation site for pertussis toxin (1988)

Fong, Henry K. W., Yoshimoto, Kenneth K., Eversole-Cire, Pamela, Simon, Melvin I.

Recent molecular cloning of cDNA for the alpha subunit of bovine transducin (a guanine nucleotide-binding regulatory protein, or G protein) has revealed the presence of two retinal-specific...

Distinct forms of the ß subunit of GTP-binding regulatory proteins identified by molecular cloning (1987)

Fong, Henry K. W., Birren, Bruce W., Simon, Melvin I.

Two distinct β subunits of guanine nucleotide-binding regulatory proteins have been identified by cDNA cloning and are referred to as β 1 and β 2 subunits. The bovine transducin β subunit (β 1)...

Repetitive Segmental Structure of the Transducin β Subunit: Homology with the CDC4 Gene and Identification of Related mRNAs (1986)

Fong, Henry K. W., Hurley, James B., Hopkins, Rosemary S., Miake-Lye, Ryn, Johnson, Mark S., Doolittle, Russell F., ...

Retinal transducin, a guanine nucleotide regulatory protein (referred to as a G protein) that activates a cGMP phosphodiesterase in photoreceptor cells, is comprised of three subunits. We have...

Isolation and Characterization of a cDNA Clone for the gamma Subunit of Bovine Retinal Transducin (1984)

Hurley, James B., Fong, Henry K. W., Teplow, David B., Dreyer, William J., Simon, Melvin I.

We have isolated and characterized a cDNA clone that encodes the gamma subunit of transducin, the guanine nucleotide binding regulatory protein found in vertebrate photoreceptors. The gamma subunit...

Recovery of Visual Functions in a Mouse Model of Leber Congenital Amaurosis*

Van Hooser, J. Preston, Liang, Yan, Maeda, Tadao, Kuksa, Vladimir, Jang, Geeng-Fu, He, Yu-Guang, ...

The visual process is initiated by the photoisomerization of 11-cis-retinal to all-trans-retinal. For sustained vision the 11-cis-chromophore must be regenerated from all-trans-retinal. This requires...