Structure of the transcriptional regulator LmrR and its mechanism of multidrug recognition (2009)
Driessen, Arnold J.M., Agustiandari, Herfita, Madoori, Pramod Kumar
LmrR is a PadR-related transcriptional repressor that regulates the production of LmrCD, a major multidrug ABC transporter in Lactococcus lactis. Transcriptional regulation is presumed to follow a...
Agustiandari, Herfita, Lubelski, Jacek, Kuipers, Oscar P., Driessen, Arnold J.M.
LmrCD is an ABC-type multidrug transporter in Lactococcus lactis. LmrR encodes a putative transcriptional regulator. In a ΔlmrR strain, lmrCD is up-regulated. LmrR binds the promoter region of lmrCD...
Zaidi, Arsalan Haseeb, Bakkes, Patrick J., Lubelski, Jacek, Agustiandari, Herfita, Kuipers, Oscar P., Driessen, Arnold J.M.
Upon prolonged exposure to cholate and other toxic compounds, Lactococcus lactis develops a multidrug resistance phenotype that has been attributed to an elevated expression of the heterodimeric...
LmrCD is a major multidrug resistance transporter in Lactococcus lactis (2006)
Lubelski, Jacek, Jong, Anne De, Merkerk, Ronald Van, Agustiandari, Herfita, Kuipers, Oscar P., Kok, Jan, ...
When Lactococcus lactis is challenged with drugs it displays a multidrug resistance (MDR) phenotype. In silico analysis of the genome of L. lactis indicates the presence of at least 40 putative MDR...
Agustiandari, Herfita, Lubelski, Jacek, Kuipers, Oscar P., Driessen, Arnold J. M.
LmrCD is an ABC-type multidrug transporter in Lactococcus lactis. LmrR encodes a putative transcriptional regulator. In a ΔlmrR strain, lmrCD is up-regulated. LmrR binds the promoter region of lmrCD...
Zaidi, Arsalan Haseeb, Bakkes, Patrick J., Lubelski, Jacek, Agustiandari, Herfita, Kuipers, Oscar P., Driessen, Arnold J. M.
Upon prolonged exposure to cholate and other toxic compounds, Lactococcus lactis develops a multidrug resistance phenotype that has been attributed to an elevated expression of the heterodimeric...