Parasitism and Mutualism in Wolbachia: What the Phylogenomic Trees Can and Cannot Say (2009)
Bordenstein, Seth R., Paraskevopoulos, Charalampos, Dunning Hotopp, Julie C., Sapountzis, Panagiotis, Lo, Nathan, Bandi, Claudio, ...
Ecological and evolutionary theories predict that parasitism and mutualism are not fixed endpoints of the symbiotic spectrum. Rather, parasitism and mutualism may be host or environment dependent,...
Sheng-mei Jiang, Nadeeza Ishmael, Manuela Puliti, Luciana Tissi, Nikhil Kumar, ...
in the group B Streptococcus CsrRS regulon and effects on pathogenicity
Correction: Comparative Genomics of Emerging Human Ehrlichiosis Agents (2006)
Mingqun Lin, Ramana Madupu, Jonathan Crabtree, Samuel V. Angiuoli, Jonathan A. Eisen, ...
Comparative Genomics of Emerging Human Ehrlichiosis Agents (2006)
Mingqun Lin, Ramana Madupu, Jonathan Crabtree, Samuel V. Angiuoli, Jonathan Eisen, ...
Anaplasma (formerly Ehrlichia) phagocytophilum, Ehrlichia chaffeensis, and Neorickettsia (formerly Ehrlichia) sennetsu are intracellular vector-borne pathogens that cause human ehrlichiosis, an...
Savard, Joël, Tautz, Diethard, Richards, Stephen, Weinstock, George M., Gibbs, Richard A., Werren, John H., ...
Comparative studies require knowledge of the evolutionary relationships between taxa. However, neither morphological nor paleontological data have been able to unequivocally resolve the major groups...
Savard, Joël, Tautz, Diethard, Richards, Stephen, Weinstock, George M., Gibbs, Richard A., Werren, John H., ...
Comparative studies require knowledge of the evolutionary relationships between taxa. However, neither morphological nor paleontological data have been able to unequivocally resolve the major groups...
Naomi Ward, Øivind Larsen, James Sakwa, Live Bruseth, Hoda Khouri, A. Scott Durkin, ...
Methanotrophs are bacteria that use methane as a sole carbon source. The genome sequence of Methylococcus capsulatus deepens our understanding of methanotroph biology and its relationship to global...
Naomi Ward, Øivind Larsen, James Sakwa, Live Bruseth, Hoda Khouri, A. Scott Durkin, ...
Methanotrophs are ubiquitous bacteria that can use the greenhouse gas methane as a sole carbon and energy source for growth, thus playing major roles in global carbon cycles, and in particular,...
Ward, Naomi, Larsen, Øivind, Sakwa, James, Bruseth, Live, Khouri, Hoda, Durkin, A. Scott, ...
Methanotrophs are ubiquitous bacteria that can use the greenhouse gas methane as a sole carbon and energy source for growth, thus playing major roles in global carbon cycles, and in particular,...
Martin Wu, Ling V. Sun, Jessica Vamathevan, Markus Riegler, Robert Deboy, Jeremy C. Brownlie, ...
The genome sequence of Wolbachia provides insights into the origins of mitochondria, as well as the ecology and evolution of endosymbiosis.
Martin Wu, Ling V. Sun, Jessica Vamathevan, Markus Riegler, Robert Deboy, Jeremy C. Brownlie, ...
The complete sequence of the 1,267,782 bp genome of Wolbachia pipientis wMel, an obligate intracellular bacteria of Drosophila melanogaster, has been determined. Wolbachia, which are found in a...
Wu, Martin, Sun, Ling V., Vamathevan, Jessica, Riegler, Markus, Deboy, Robert, Brownlie, Jeremy C., ...
The complete sequence of the 1,267,782 bp genome of Wolbachia pipientis wMel, an obligate intracellular bacteria of Drosophila melanogaster, has been determined. Wolbachia, which are found in a...
Interpolated Markov models for eukaryotic gene finding (1999)
Steven L. Salzberg, Mihaela Pertea, Arthur L. Delcher, Malcolm J. Gardner, Hervé Tettelin
Computational gene finding research has emphasized the development of gene finders for bacterial and human DNA. This has left genome projects for some small eukaryotes without a system that addresses...
Optimized multiplex PCR: efficiently closing a whole-genome shotgun sequencing project (1999)
Hervé Tettelin, Diana Radune, Simon Kasif, Hoda Khouri, Steven L. Salzberg
A new method has been developed for rapidly closing a large number of gaps in a whole-genome shotgun sequencing project. The method employs multiplex PCR and a novel pooling strategy to minimize the...
Optical Mapping of Plasmodium falciparum Chromosome 2 (1999)
Jing, Junping, Lai, Zhongwu, Aston, Christopher, Lin, Jieyi, Carucci, Daniel J., Gardner, Malcolm J., ...
Peterson, Scott, Cline, Robin T., Tettelin, Hervé, Sharov, Vasily, Morrison, Donald A.
Competence for genetic transformation in Streptococcus pneumoniae is coordinated by the competence-stimulating peptide (CSP), which induces a sudden and transient appearance of competence during...
Mu-Like Prophage in Serogroup B Neisseria meningitidis Coding for Surface-Exposed Antigens
Masignani, Vega, Giuliani, Marzia Monica, Tettelin, Hervé, Comanducci, Maurizio, Rappuoli, Rino, Scarlato, Vincenzo
Sequence analysis of the genome of Neisseria meningititdis serogroup B revealed the presence of an ∼35-kb region inserted within a putative gene coding for an ABC-type transporter. The region...
Eisen, Jonathan A., Nelson, Karen E., Paulsen, Ian T., Heidelberg, John F., Wu, Martin, Dodson, Robert J., ...
The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum...
Tettelin, Hervé, Masignani, Vega, Cieslewicz, Michael J., Eisen, Jonathan A., Peterson, Scott, Wessels, Michael R., ...
The 2,160,267 bp genome sequence of Streptococcus agalactiae, the leading cause of bacterial sepsis, pneumonia, and meningitis in neonates in the U.S. and Europe, is predicted to encode 2,175 genes....
Complete genome sequence of the Q-fever pathogen Coxiella burnetii
Seshadri, Rekha, Paulsen, Ian T., Eisen, Jonathan A., Read, Timothy D., Nelson, Karen E., Nelson, William C., ...
The 1,995,275-bp genome of Coxiella burnetii, Nine Mile phase I RSA493, a highly virulent zoonotic pathogen and category B bioterrorism agent, was sequenced by the random shotgun method. This...
Complete Genome Sequence of the Oral Pathogenic Bacterium Porphyromonas gingivalis Strain W83
Nelson, Karen E., Fleischmann, Robert D., DeBoy, Robert T., Paulsen, Ian T., Fouts, Derrick E., Eisen, Jonathan A., ...
The complete 2,343,479-bp genome sequence of the gram-negative, pathogenic oral bacterium Porphyromonas gingivalis strain W83, a major contributor to periodontal disease, was determined. Whole-genome...
Complete Genome Sequence of the Oral Pathogenic Bacterium Porphyromonas gingivalis Strain W83
Nelson, Karen E., Fleischmann, Robert D., DeBoy, Robert T., Paulsen, Ian T., Fouts, Derrick E., Eisen, Jonathan A., ...
Optical Mapping of Plasmodium falciparum Chromosome 2
Jing, Junping, Lai, Zhongwu, Aston, Christopher, Lin, Jieyi, Carucci, Daniel J., Gardner, Malcolm J., ...
Detailed restriction maps of microbial genomes are a valuable resource in genome sequencing studies but are toilsome to construct by contig construction of maps derived from cloned DNA. Analysis of...
Wu, Martin, Sun, Ling V, Vamathevan, Jessica, Riegler, Markus, Deboy, Robert, Brownlie, Jeremy C, ...
The complete sequence of the 1,267,782 bp genome of Wolbachia pipientis wMel, an obligate intracellular bacteria of Drosophila melanogaster, has been determined. Wolbachia, which are found in a...
Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes
Seshadri, Rekha, Myers, Garry S. A., Tettelin, Hervé, Eisen, Jonathan A., Heidelberg, John F., Dodson, Robert J., ...
We present the complete 2,843,201-bp genome sequence of Treponema denticola (ATCC 35405) an oral spirochete associated with periodontal disease. Analysis of the T. denticola genome reveals factors...
Genomic Insights into Methanotrophy: The Complete Genome Sequence of Methylococcus capsulatus (Bath)
Ward, Naomi, Larsen, Øivind, Sakwa, James, Bruseth, Live, Khouri, Hoda, Durkin, A. Scott, ...
Methanotrophs are ubiquitous bacteria that can use the greenhouse gas methane as a sole carbon and energy source for growth, thus playing major roles in global carbon cycles, and in particular,...
Tettelin, Hervé, Masignani, Vega, Cieslewicz, Michael J., Donati, Claudio, Medini, Duccio, Ward, Naomi L., ...
The development of efficient and inexpensive genome sequencing methods has revolutionized the study of human bacterial pathogens and improved vaccine design. Unfortunately, the sequence of a single...
Identification of a Universal Group B Streptococcus Vaccine by Multiple Genome Screen
Maione, Domenico, Margarit, Immaculada, Rinaudo, Cira D., Masignani, Vega, Mora, Marirosa, Scarselli, Maria, ...
Group B Streptococcus (GBS) is a multiserotype bacterial pathogen representing a major cause of life-threatening infections in newborns. To develop a broadly protective vaccine, we analyzed the...
Comparative Genomics of Emerging Human Ehrlichiosis Agents
Dunning Hotopp, Julie C., Lin, Mingqun, Madupu, Ramana, Crabtree, Jonathan, Angiuoli, Samuel V, Eisen, Jonathan, ...
Anaplasma (formerly Ehrlichia) phagocytophilum, Ehrlichia chaffeensis, and Neorickettsia (formerly Ehrlichia) sennetsu are intracellular vector-borne pathogens that cause human ehrlichiosis, an...
Peterson, Scott, Cline, Robin T., Tettelin, Hervé, Sharov, Vasily, Morrison, Donald A.
Competence for genetic transformation in Streptococcus pneumoniae is coordinated by the competence-stimulating peptide (CSP), which induces a sudden and transient appearance of competence during...
Mu-Like Prophage in Serogroup B Neisseria meningitidis Coding for Surface-Exposed Antigens
Masignani, Vega, Giuliani, Marzia Monica, Tettelin, Hervé, Comanducci, Maurizio, Rappuoli, Rino, Scarlato, Vincenzo
Sequence analysis of the genome of Neisseria meningititdis serogroup B revealed the presence of an ∼35-kb region inserted within a putative gene coding for an ABC-type transporter. The region...
Eisen, Jonathan A., Nelson, Karen E., Paulsen, Ian T., Heidelberg, John F., Wu, Martin, Dodson, Robert J., ...
The complete genome of the green-sulfur eubacterium Chlorobium tepidum TLS was determined to be a single circular chromosome of 2,154,946 bp. This represents the first genome sequence from the phylum...
Tettelin, Hervé, Masignani, Vega, Cieslewicz, Michael J., Eisen, Jonathan A., Peterson, Scott, Wessels, Michael R., ...
The 2,160,267 bp genome sequence of Streptococcus agalactiae, the leading cause of bacterial sepsis, pneumonia, and meningitis in neonates in the U.S. and Europe, is predicted to encode 2,175 genes....
Complete genome sequence of the Q-fever pathogen Coxiella burnetii
Seshadri, Rekha, Paulsen, Ian T., Eisen, Jonathan A., Read, Timothy D., Nelson, Karen E., Nelson, William C., ...
The 1,995,275-bp genome of Coxiella burnetii, Nine Mile phase I RSA493, a highly virulent zoonotic pathogen and category B bioterrorism agent, was sequenced by the random shotgun method. This...
Complete Genome Sequence of the Oral Pathogenic Bacterium Porphyromonas gingivalis Strain W83
Nelson, Karen E., Fleischmann, Robert D., DeBoy, Robert T., Paulsen, Ian T., Fouts, Derrick E., Eisen, Jonathan A., ...
The complete 2,343,479-bp genome sequence of the gram-negative, pathogenic oral bacterium Porphyromonas gingivalis strain W83, a major contributor to periodontal disease, was determined. Whole-genome...
Complete Genome Sequence of the Oral Pathogenic Bacterium Porphyromonas gingivalis Strain W83
Nelson, Karen E., Fleischmann, Robert D., DeBoy, Robert T., Paulsen, Ian T., Fouts, Derrick E., Eisen, Jonathan A., ...
Optical Mapping of Plasmodium falciparum Chromosome 2
Jing, Junping, Lai, Zhongwu, Aston, Christopher, Lin, Jieyi, Carucci, Daniel J., Gardner, Malcolm J., ...
Detailed restriction maps of microbial genomes are a valuable resource in genome sequencing studies but are toilsome to construct by contig construction of maps derived from cloned DNA. Analysis of...
Wu, Martin, Sun, Ling V, Vamathevan, Jessica, Riegler, Markus, Deboy, Robert, Brownlie, Jeremy C, ...
The complete sequence of the 1,267,782 bp genome of Wolbachia pipientis wMel, an obligate intracellular bacteria of Drosophila melanogaster, has been determined. Wolbachia, which are found in a...
Comparison of the genome of the oral pathogen Treponema denticola with other spirochete genomes
Seshadri, Rekha, Myers, Garry S. A., Tettelin, Hervé, Eisen, Jonathan A., Heidelberg, John F., Dodson, Robert J., ...
We present the complete 2,843,201-bp genome sequence of Treponema denticola (ATCC 35405) an oral spirochete associated with periodontal disease. Analysis of the T. denticola genome reveals factors...
Genomic Insights into Methanotrophy: The Complete Genome Sequence of Methylococcus capsulatus (Bath)
Ward, Naomi, Larsen, Øivind, Sakwa, James, Bruseth, Live, Khouri, Hoda, Durkin, A. Scott, ...
Methanotrophs are ubiquitous bacteria that can use the greenhouse gas methane as a sole carbon and energy source for growth, thus playing major roles in global carbon cycles, and in particular,...
Tettelin, Hervé, Masignani, Vega, Cieslewicz, Michael J., Donati, Claudio, Medini, Duccio, Ward, Naomi L., ...
The development of efficient and inexpensive genome sequencing methods has revolutionized the study of human bacterial pathogens and improved vaccine design. Unfortunately, the sequence of a single...
Comparative Genomics of Emerging Human Ehrlichiosis Agents
Dunning Hotopp, Julie C., Lin, Mingqun, Madupu, Ramana, Crabtree, Jonathan, Angiuoli, Samuel V, Eisen, Jonathan, ...
Anaplasma (formerly Ehrlichia) phagocytophilum, Ehrlichia chaffeensis, and Neorickettsia (formerly Ehrlichia) sennetsu are intracellular vector-borne pathogens that cause human ehrlichiosis, an...
Correction: Comparative Genomics of Emerging Human Ehrlichiosis Agents
Dunning Hotopp, Julie C, Lin, Mingqun, Madupu, Ramana, Crabtree, Jonathan, Angiuoli, Samuel V, Eisen, Jonathan A, ...
Lanie, Joel A., Ng, Wai-Leung, Kazmierczak, Krystyna M., Andrzejewski, Tiffany M., Davidsen, Tanja M., Wayne, Kyle J., ...
Streptococcus pneumoniae (pneumococcus) is a leading human respiratory pathogen that causes a variety of serious mucosal and invasive diseases. D39 is an historically important serotype 2 strain that...
Savard, Joël, Tautz, Diethard, Richards, Stephen, Weinstock, George M., Gibbs, Richard A., Werren, John H., ...
Comparative studies require knowledge of the evolutionary relationships between taxa. However, neither morphological nor paleontological data have been able to unequivocally resolve the major groups...
Variation in the Group B Streptococcus CsrRS Regulon and Effects on Pathogenicity▿ †
Jiang, Sheng-Mei, Ishmael, Nadeeza, Hotopp, Julie Dunning, Puliti, Manuela, Tissi, Luciana, Kumar, Nikhil, ...
CsrRS (or CovRS) is a two-component regulatory system that controls expression of multiple virulence factors in the important human pathogen group B Streptococcus (GBS). We now report global gene...
Evolution of Streptococcus pneumoniae and Its Close Commensal Relatives
Kilian, Mogens, Poulsen, Knud, Blomqvist, Trinelise, Håvarstein, Leiv S., Bek-Thomsen, Malene, Tettelin, Hervé, ...
Streptococcus pneumoniae is a member of the Mitis group of streptococci which, according to 16S rRNA-sequence based phylogenetic reconstruction, includes 12 species. While other species of this group...
Bek-Thomsen, Malene, Tettelin, Hervé, Hance, Ioana, Nelson, Karen E., Kilian, Mogens
We reinvestigated the clonal diversity and dynamics of Streptococcus mitis and two other abundant members of the commensal microbiota of the upper respiratory tract, Streptococcus oralis and...