DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange (2009)
Ishida, Takako, Takizawa, Yoshimasa, Kainuma, Takashi, Inoue, Jin, Mikawa, Tsutomu, Shibata, Takehiko, ...
RAD51, an essential eukaryotic DNA recombinase, promotes homologous pairing and strand exchange during homologous recombination and the recombinational repair of double strand breaks. Mutations that...
Relapse of Stage I Small Cell Lung Cancer Ten or More Years after the Start of Treatment (2006)
Matsui, Kaoru, Sawa, Toshiyuki, Suzuki, Hidekazu, Nakagawa, Katsuhiro, Okamoto, Norio, Tada, Takuhito, ...
Most patients with small cell lung cancer (SCLC) usually show relapse within 1 or 2 years. Relapses after a 5-year disease-free survival are extremely rare. This report describes two patients with...
Relapse of Stage I Small Cell Lung Cancer Ten or More Years after the Start of Treatment (2006)
Matsui, Kaoru, Sawa, Toshiyuki, Suzuki, Hidekazu, Nakagawa, Katsuhiro, Okamoto, Norio, Tada, Takuhito, ...
Most patients with small cell lung cancer (SCLC) usually show relapse within 1 or 2 years. Relapses after a 5-year disease-free survival are extremely rare. This report describes two patients with...
Previously Unknown Virus Infects Marine Diatom (2004)
Keizo Nagasaki, Yuji Tomaru, Yoshitake Takao, Kensho Nishida, Yoko Shirai, Hidekazu Suzuki, ...
Diatoms are a major phytoplankton group that play important roles in maintaining oxygen levels in the atmosphere and sustaining the primary nutritional production of the aquatic environment. Among...
Mima, Joji, Suzuki, Hidekazu, Takahashi, Mieko, Hayashi, Rikimaru
Carboxypeptidase Y (CPY) inhibitor, Ic, a cytoplasmic inhibitor of vacuolar proteinases in yeast, Saccharomyces cerevisiae, was purified by means of a high-level expression system using a...
Immunocytochemical Evaluation of Trichinella spiralis Larval Antigen (1990)
Takahashi, Yuzo, Uno, Takako, Mizuno, Naoto, Suzuki, Hidekazu, Wada, Teruo, Araki, Tsuneji
The antigenicity of Trichinella spiralis muscle larvae was studied for the purpose of developing an immunodiagnostic test for trichinosis. Ultrathin sections of fixed larvae were treated with sera...
Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats
Suzuki, Hidekazu, DeLano, Frank A., Parks, Dale A., Jamshidi, Neema, Granger, D. Neil, Ishii, Hiromasa, ...
Recent evidence in vivo indicates that spontaneously hypertensive rats (SHR) exhibit an increase in oxyradical production in and around microvascular endothelium. This study is aimed to examine...
Previously Unknown Virus Infects Marine Diatom
Nagasaki, Keizo, Tomaru, Yuji, Takao, Yoshitake, Nishida, Kensho, Shirai, Yoko, Suzuki, Hidekazu, ...
Diatoms are a major phytoplankton group that play important roles in maintaining oxygen levels in the atmosphere and sustaining the primary nutritional production of the aquatic environment. Among...
Nishizawa, Toshihiro, Suzuki, Hidekazu, Kurabayashi, Kumiko, Masaoka, Tatsuhiro, Muraoka, Hiroe, Mori, Mikiji, ...
A high resistance rate (47.9%) to gatifloxacin (GAT; 8-methoxy fluoroquinolone) in Helicobacter pylori (H. pylori) strains from 48 Japanese patients is observed after unsuccessful H. pylori...
Xanthine oxidase activity associated with arterial blood pressure in spontaneously hypertensive rats
Suzuki, Hidekazu, DeLano, Frank A., Parks, Dale A., Jamshidi, Neema, Granger, D. Neil, Ishii, Hiromasa, ...
Recent evidence in vivo indicates that spontaneously hypertensive rats (SHR) exhibit an increase in oxyradical production in and around microvascular endothelium. This study is aimed to examine...
Previously Unknown Virus Infects Marine Diatom
Nagasaki, Keizo, Tomaru, Yuji, Takao, Yoshitake, Nishida, Kensho, Shirai, Yoko, Suzuki, Hidekazu, ...
Diatoms are a major phytoplankton group that play important roles in maintaining oxygen levels in the atmosphere and sustaining the primary nutritional production of the aquatic environment. Among...
Nishizawa, Toshihiro, Suzuki, Hidekazu, Kurabayashi, Kumiko, Masaoka, Tatsuhiro, Muraoka, Hiroe, Mori, Mikiji, ...
A high resistance rate (47.9%) to gatifloxacin (GAT; 8-methoxy fluoroquinolone) in Helicobacter pylori (H. pylori) strains from 48 Japanese patients is observed after unsuccessful H. pylori...
Nishizawa, Toshihiro, Suzuki, Hidekazu, Umezawa, Ayako, Muraoka, Hiroe, Iwasaki, Eisuke, Masaoka, Tatsuhiro, ...
Helicobacter pylori strains with reduced susceptibility to fluoroquinolones have a mutation at either codon 87 Asn or 91 Asp of the gyrA gene. A rapid test based on an allele-specific PCR (AS-PCR)...
Proton Pump Inhibitors and Gastritis
Suzuki, Masayuki, Suzuki, Hidekazu, Hibi, Toshifumi
Proton pump inhibitors (PPIs) are novel compounds that strongly inhibit the H+/K+-ATPase in the gastric parietal cells to cause profound suppression of acid secretion. Acid-generating ATPase, also...
Gastric Epithelial Cell Modality and Proton Pump Inhibitor
Masaoka, Tatsuhiro, Suzuki, Hidekazu, Hibi, Toshifumi
Proton pump inhibitors (PPIs) are now commonly used for the treatment of acid related diseases such as peptic ulcer and reflux esophagitis. Because of their ability to produce direct inhibition of...
Asahi, Atsuko, Nishimoto, Tetsuya, Okazaki, Yuka, Suzuki, Hidekazu, Masaoka, Tatsuhiro, Kawakami, Yutaka, ...
Immune thrombocytopenia purpura (ITP) is a bleeding disorder in which platelet-specific autoantibodies cause a loss of platelets. In a subset of patients with ITP and infected with Helicobacter...
Shirai, Yoko, Tomaru, Yuji, Takao, Yoshitake, Suzuki, Hidekazu, Nagumo, Tamotsu, Nagasaki, Keizo
Diatoms are important components of the biological community and food web in the aquatic environment. Here, we report the characteristics of a single-stranded RNA (ssRNA) virus (CtenRNAV01) that...
Quinolone-Based Third-Line Therapy for Helicobacter pylori Eradication
Nishizawa, Toshihiro, Suzuki, Hidekazu, Hibi, Toshifumi
Currently, a standard third-line therapy for Helicobacter pylori (H. pylori) eradication remains to be established. Quinolones show good oral absorption, no major side effects, and marked activity...
DIDS, a chemical compound that inhibits RAD51-mediated homologous pairing and strand exchange
Ishida, Takako, Takizawa, Yoshimasa, Kainuma, Takashi, Inoue, Jin, Mikawa, Tsutomu, Shibata, Takehiko, ...
RAD51, an essential eukaryotic DNA recombinase, promotes homologous pairing and strand exchange during homologous recombination and the recombinational repair of double strand breaks. Mutations that...
Tomaru, Yuji, Takao, Yoshitake, Suzuki, Hidekazu, Nagumo, Tamotsu, Nagasaki, Keizo
Diatoms are very significant primary producers in the world's oceans. Various environmental factors affect the depletion of diatom populations. The importance of viruses as a potential mortality...
Helicobacter pylori: present status and future prospects in Japan
Suzuki, Hidekazu, Hibi, Toshifumi, Marshall, Barry James
The discovery of Helicobacter pylori has already changed the natural history of peptic ulcer disease, with most patients being cured at their first presentation. Similarly, the incidence of gastric...