Seki, Yoshitaka, Okusaka, Takuji, Ikeda, Masafumi, Morizane, Chigusa, Ueno, Hideki
Pancreatic acinar cell carcinoma (ACC) is a comparatively rare tumor and account for ∼1% of all cases of pancreatic cancer. Clinical presentation is usually related to either local spread or...
Ikeda, Masafumi, Okusaka, Takuji, Ueno, Hideki, Morizane, Chigusa, Kojima, Yasushi, Iwasa, Satoru, ...
Objective Systemic chemotherapy is an important treatment modality for metastatic hepatocellular carcinoma (HCC); however, the predictive factors of outcome and tumor response have not been fully...
Tanaka, Tsutomu, Ikeda, Masafumi, Okusaka, Takuji, Ueno, Hideki, Morizane, Chigusa, Hagihara, Atsushi, ...
Objective The purpose of the retrospective analysis is to elucidate the treatment efficacy and toxicity as well as to identify prognostic factors in Japanese patients with advanced pancreatic cancer...
Immunological intervention in human diseases (2007)
Ueno, Hideki, Hawrylowicz, Catherine M, Banchereau, Jacques
Abstract A recent Keystone Symposium Meeting on "Immunological Intervention in Human Disease" was held in Big Sky, Montana on January, 6–11, 2007, organized by Jacques Banchereau, Federica Sallusto...
Ueno, Hideki, Okusaka, Takuji, Ikeda, Masafumi, Morizane, Chigusa, Ogura, Takashi, Hagihara, Atsushi, ...
Objective The objectives of this study were to evaluate the efficacy and toxicity of combination chemotherapy with gemcitabine and cisplatin in patients with metastatic pancreatic cancer. Methods...
Kobayashi, Hirotoshi, Ueno, Hideki, Hashiguchi, Yojiro, Ishiguro, Megumi, Omata, Jiro, Kajiwara, Yoshiki, ...
Neuroendocrine carcinomas of the anal canal are rare, representing 1% of malignant tumors of the anal canal. This tumor behaves aggressively and leads to poor outcomes. The majority of tumors are...
Kobayashi, Hirotoshi, Ueno, Hideki, Hashiguchi, Yojiro, Ishiguro, Megumi, Omata, Jiro, Kajiwara, Yoshiki, ...
Neuroendocrine carcinomas of the anal canal are rare, representing 1% of malignant tumors of the anal canal. This tumor behaves aggressively and leads to poor outcomes. The majority of tumors are...
Okusaka, Takuji, Ishii, Hiroshi, Funakoshi, Akihiro, Ueno, Hideki, Furuse, Junji, Sumii, Toshihiko
Background: In an effort to improve efficacy of single-agent gemcitabine in pancreatic cancer, several studies have examined the effects of 5-FU combined with gemcitabine. However, no studies to date...
Furuse, Junji, Okusaka, Takuji, Funakoshi, Akihiro, Yamao, Kenji, Nagase, Michitaka, Ishii, Hiroshi, ...
Background: Standard chemotherapy for advanced biliary tract cancer has not been established. The purpose of this study was to evaluate the efficacy and toxicity of a combination chemotherapy of...
Furuse, Junji, Okusaka, Takuji, Funakoshi, Akihiro, Yamao, Kenji, Nagase, Michitaka, Ishii, Hiroshi, ...
Background: Standard chemotherapy for advanced biliary tract cancer has not been established. The purpose of this study was to evaluate the efficacy and toxicity of a combination chemotherapy of...
Okusaka, Takuji, Ishii, Hiroshi, Funakoshi, Akihiro, Ueno, Hideki, Furuse, Junji, Sumii, Toshihiko
Background: In an effort to improve efficacy of single-agent gemcitabine in pancreatic cancer, several studies have examined the effects of 5-FU combined with gemcitabine. However, no studies to date...
Kayo Nakamura, Hideki Ueno, Kazuki Miura
Maternally inherited bacteria that kill male but not female hosts during embryogenesis occur in Harmonia axyridis (Pallas). In two populations in Japan, Fukuyama, Hiroshima, and Muikamachi, Niigata,...
A Phase II Trial of Uracil-Tegafur (UFT) in Patients with Advanced Biliary Tract Carcinoma (2005)
Ikeda, Masafumi, Okusaka, Takuji, Ueno, Hideki, Morizane, Chigusa, Furuse, Junji, Ishii, Hiroshi
Background: Uracil-tegafur (UFT) has been reported to have broad antitumor activity in a variety of malignancies. However, its activity in biliary tract carcinoma has not been fully evaluated. The...
Furuse, Junji, Ishii, Hiroshi, Okusaka, Takuji, Nagase, Michitaka, Nakachi, Kohei, Ueno, Hideki, ...
Objective: The purpose of this study was to determine the feasible dose of gemcitabine when administered as a fixed dose rate infusion (10 mg/m2/min) on a weekly schedule to Japanese patients with...
A Phase II Trial of Uracil-Tegafur (UFT) in Patients with Advanced Biliary Tract Carcinoma (2005)
Ikeda, Masafumi, Okusaka, Takuji, Ueno, Hideki, Morizane, Chigusa, Furuse, Junji, Ishii, Hiroshi
Background: Uracil–tegafur (UFT) has been reported to have broad antitumor activity in a variety of malignancies. However, its activity in biliary tract carcinoma has not been fully evaluated. The...
Furuse, Junji, Ishii, Hiroshi, Okusaka, Takuji, Nagase, Michitaka, Nakachi, Kohei, Ueno, Hideki, ...
Objective: The purpose of this study was to determine the feasible dose of gemcitabine when administered as a fixed dose rate infusion (10 mg/m2/min) on a weekly schedule to Japanese patients...
A Phase II Trial of Uracil-Tegafur (UFT) in Patients with Advanced Biliary Tract Carcinoma (2005)
Ikeda, Masafumi, Okusaka, Takuji, Ueno, Hideki, Morizane, Chigusa, Furuse, Junji, Ishii, Hiroshi
Background: Uracil-tegafur (UFT) has been reported to have broad antitumor activity in a variety of malignancies. However, its activity in biliary tract carcinoma has not been fully evaluated. The...
Furuse, Junji, Ishii, Hiroshi, Okusaka, Takuji, Nagase, Michitaka, Nakachi, Kohei, Ueno, Hideki, ...
Objective: The purpose of this study was to determine the feasible dose of gemcitabine when administered as a fixed dose rate infusion (10 mg/m2/min) on a weekly schedule to Japanese patients with...
Ikeda, Masafumi, Okada, Shuichi, Yamamoto, Seiichiro, Sato, Tosiya, Ueno, Hideki, Okusaka, Takuji, ...
Background: Transcatheter arterial embolization induces marked antitumor response in patients with hepatocellular carcinoma, but the survival benefit of transcatheter arterial embolization remains to...
Phase I Trial of Gemcitabine in Patients with Advanced Pancreatic Cancer (2001)
Okada, Shuichi, Ueno, Hideki, Okusaka, Takuji, Ikeda, Masafumi, Furuse, Junji, Maru, Yasushi
Background: Gemcitabine is the most promising new agent currently being tested in pancreatic cancer. The present study was conducted to confirm the tolerability of a weekly schedule of gemcitabine at...
Ikeda, Masafumi, Okada, Shuichi, Ueno, Hideki, Okusaka, Takuji, Kuriyama, Hitoshi
Spontaneous regression of hepatocellular carcinoma is an extraordinarily unusual phenomenon. We present here a case of a 75-year-old man in whom multiple lung metastases of hepatocellular carcinoma...
Ikeda, Masafumi, Okada, Shuichi, Ueno, Hideki, Okusaka, Takuji, Kuriyama, Hitoshi
Background: Radiofrequency ablation (RFA) is a novel thermal ablation technique to achieve coagulative necrosis of hepatocellular carcinoma. A study was conducted to compare the antitumor effect and...
Akatsuka, Yutaka, Egashira, Kensuke, Katsuda, Yousuke, Narishige, Takahiro, Ueno, Hideki, Shimokawa, Hiroaki, ...
Objective: The aim was to determine a role of ATP sensitive potassium (KATP) channels in adenosine A2 receptor mediated coronary vasodilatation in anaesthetised dogs in vivo. Methods: Coronary blood...
Ueno, Hideki, Mochizuki, Hidetaka, Hashiguchi, Yojiro, Ishikawa, Keiichi, Fujimoto, Hajime, Shinto, Eiji, ...
The preoperative evaluation of 3 parameters (histologic characteristics in the submucosal region, annularity, and gross appearance of tumor, which were selected as independent parameters of...
A New Prognostic Staging System for Rectal Cancer
Ueno, Hideki, Price, Ashley B., Wilkinson, Kay H., Jass, Jeremy R., Mochizuki, Hidetaka, Talbot, Ian C.
Based on 2 discrete cohorts of rectal cancer patients, tumor “budding” was identified as a reproducible independent prognostic indicator that can improve the erroneous staging of advanced disease...
Indicators for Treatment Strategies of Colorectal Liver Metastases
Ueno, Hideki, Mochizuki, Hidetaka, Hatsuse, Kazuo, Hase, Kazuo, Yamamoto, Tetsuhisa
Prognostic Determinants of Patients With Lateral Nodal Involvement by Rectal Cancer
Ueno, Hideki, Mochizuki, Hidetaka, Hashiguchi, Yojiro, Hase, Kazuo
Miyoshi, Masayoshi, Ueno, Hideki, Hashiguchi, Yojiro, Mochizuki, Hidetaka, Talbot, Ian C.
The extent of mesorectal tumor invasion was evaluated using 2 data sets comprising 196 and 247 patients at separate institutes to determine the significance of it as a prognostic factor for T3 rectal...
Ueno, Hideki, Mochizuki, Hidetaka, Hashiguchi, Yojiro, Ishikawa, Keiichi, Fujimoto, Hajime, Shinto, Eiji, ...
The preoperative evaluation of 3 parameters (histologic characteristics in the submucosal region, annularity, and gross appearance of tumor, which were selected as independent parameters of...
A New Prognostic Staging System for Rectal Cancer
Ueno, Hideki, Price, Ashley B., Wilkinson, Kay H., Jass, Jeremy R., Mochizuki, Hidetaka, Talbot, Ian C.
Based on 2 discrete cohorts of rectal cancer patients, tumor “budding” was identified as a reproducible independent prognostic indicator that can improve the erroneous staging of advanced disease...
Indicators for Treatment Strategies of Colorectal Liver Metastases
Ueno, Hideki, Mochizuki, Hidetaka, Hatsuse, Kazuo, Hase, Kazuo, Yamamoto, Tetsuhisa
Prognostic Determinants of Patients With Lateral Nodal Involvement by Rectal Cancer
Ueno, Hideki, Mochizuki, Hidetaka, Hashiguchi, Yojiro, Hase, Kazuo
Miyoshi, Masayoshi, Ueno, Hideki, Hashiguchi, Yojiro, Mochizuki, Hidetaka, Talbot, Ian C.
The extent of mesorectal tumor invasion was evaluated using 2 data sets comprising 196 and 247 patients at separate institutes to determine the significance of it as a prognostic factor for T3 rectal...
Ueno, Hideki, Mochizuki, Hidetaka, Hashiguchi, Yojiro, Ishiguro, Megumi, Miyoshi, Masayoshi, Kajiwara, Yoshiki, ...
Among 244 patients who underwent potentially curative surgery with lateral pelvic node dissection for advanced lower rectal cancer, lateral nodal involvement (LNI) was observed in 41 patients (17%),...
Immunological intervention in human diseases
Ueno, Hideki, Hawrylowicz, Catherine M, Banchereau, Jacques
A recent Keystone Symposium Meeting on "Immunological Intervention in Human Disease" was held in Big Sky, Montana on January, 6–11, 2007, organized by Jacques Banchereau, Federica Sallusto and...
Circulating tumor antigen-specific regulatory T cells in patients with metastatic melanoma
Vence, Luis, Palucka, A. Karolina, Fay, Joseph W., Ito, Tomoki, Liu, Yong-Jun, Banchereau, Jacques, ...
Although it is accepted that regulatory T cells (T regs) contribute to cancer progression, most studies in the field consider nonantigen-specific suppression. Here, we show the presence of tumor...