Hirokuni Taguchi

Hematological studies on iron- and folate-requirements in pregnancy (2007)

Taguchi, Hirokuni, Sanada, Hiroshi, Hara, Koichi, Hasei, Toshio, Iwasaki, Ichiro, Sumitomo, Ryogo

Hematological changes and serum iron, vitamin B12 and folate levels after administration of iron plus folic acid were com· pared with changes and levels after supplement of iron alone in 100...

Clinical and experimental studies on folic acid deficiency due to anticonvulsants. 2. Investigations on patients receiving anticonvulsants and experimental study on the effect of diphenylhydantoin on the absorption of folic acid in rats (2007)

Taguchi, Hirokuni

A high incidence of subnormal serum folic acid levels was observed in 48 patients receiving anticonvulsants (75 %). In peripheral blood, macrocytosis was detected in 46 % and an increase of...

Clinical and experimental studies on folic acid deficiency due to anticonvulsants. I. Clinical and nutritional study on megalobastic anemia due to anticonvulsants (2007)

Taguchi, Hirokuni

Two cases of megaloblastic anemia associated with anticonvulsant drugs were studied. Both cases were inpatients of psychiatric hospitals and had quite inadequate intakes of food. The former had lung...

Folic acid metabolism in Rauscher murine leukemia and effect of methotrexate on the blood picture (2007)

Taguchi, Hirokuni, Sanada, Hiroshi

Folic acid contents of plasma, whole blood, liver and spleen in Rauscher leukemic mice were estimated. Plasma and liver folate in the leukemic mice was lower than that of normal mice, suggesting that...

Megaloblastic anemia in Japan (2007)

Taguchi, Hirokuni

Since 1903, 744 cases of megaloblastic anemia have been reported in Japan: 490 cases of pernicious anemia; 95 cases associated with pregnancy; 66 cases after gastrectomy; 22 cases of megaloblastic...

Anemia in the elderly patients with special reference to folic acid status (2007)

Taguchi, Hirokuni, Sanada, Hiroshi

To investigate the role of folic acid deficiency in the pathogenesis of anemia in the elderly, hematological examinationa and assays of serum iron, vitamin B12 and folate were carried out on the 86...

Deoxyuridine suppression test: a comparison of two methods and effect of thymidine on the incorporation of 3H-deoxyuridine into DNA in human bone marrow cells (2007)

Taguchi, Hirokuni, Stafford, Denise M., Chanarin, Israel

Deoxyuridine suppression tests have been performed by two different methods of six normoblastic and eight megaloblastic marrows. A good correlation was obtained between the results by the modified...

Cryptococcal pleural effusion in an HTLV-I carrier with Waldenstroem's macroglobulinemia. (2007)

Taguchi, Hirokuni, Kotani, Shigemitsu, Sugito, Sawa, Kobayashi, Makoto, Kubonishi, Ichiro, Miyoshi, Isao

A 70-year-old woman with Waldenstroem's macroglobulinemia developed bilateral pleural effusions due to Cryptococcus neoformans. She was found to be a carrier of HTLV-I. It is speculated that the...

Immune suppression in HTLV-I carriers: a predictive sign of adult T-cell leukemia. (2007)

Taguchi, Hirokuni, Miyoshi, Isao

Suppression of the cellular immune system appears to be a prerequisite for the manifestation of adult T-cell leukemia (ATL). In other words, ATL will develop when impairment of the immune system is...

Trichosporon beigelii Pneumonia in a Patient with Malignant Histiocytosis (1986)

KOBAYASHI, MAKOTO, MATSUOKA, TOMOKO, TAGUCHI, HIROKUNI, MORIKI, TOSHIAKI, ENZAN, HIDEAKI, HARA, HIROSHI, ...

A 30-year-old previously healthy housewife presented with bilateral pulmonary infiltrates. She was treated with various antibiotics but died with disseminated intravascular coagulation. Cultures of...

Induction of Lytic Epstein-Barr Virus (EBV) Infection by Synergistic Action of Rituximab and Dexamethasone Renders EBV-Positive Lymphoma Cells More Susceptible to Ganciclovir Cytotoxicity In Vitro and In Vivo

Daibata, Masanori, Bandobashi, Kentaro, Kuroda, Masayuki, Imai, Shosuke, Miyoshi, Isao, Taguchi, Hirokuni

The purposeful induction of the lytic form of Epstein-Barr virus (EBV) infection combined with ganciclovir (GCV) treatment has been advocated as a novel strategy for EBV-positive B-cell lymphoma. We...

A Human T-Cell Lymphotropic Virus Type 1 Enhancer of Myc Transforming Potential Stabilizes Myc-TIP60 Transcriptional Interactions

Awasthi, Soumya, Sharma, Anima, Wong, Kasuen, Zhang, Junyu, Matlock, Elizabeth F., Rogers, Lowery, ...

The human T-cell lymphotropic virus type 1 (HTLV-1) infects and transforms CD4+ lymphocytes and causes adult T-cell leukemia/lymphoma (ATLL), an aggressive lymphoproliferative disease that is often...

Induction of Lytic Epstein-Barr Virus (EBV) Infection by Synergistic Action of Rituximab and Dexamethasone Renders EBV-Positive Lymphoma Cells More Susceptible to Ganciclovir Cytotoxicity In Vitro and In Vivo

Daibata, Masanori, Bandobashi, Kentaro, Kuroda, Masayuki, Imai, Shosuke, Miyoshi, Isao, Taguchi, Hirokuni

The purposeful induction of the lytic form of Epstein-Barr virus (EBV) infection combined with ganciclovir (GCV) treatment has been advocated as a novel strategy for EBV-positive B-cell lymphoma. We...

A Human T-Cell Lymphotropic Virus Type 1 Enhancer of Myc Transforming Potential Stabilizes Myc-TIP60 Transcriptional Interactions

Awasthi, Soumya, Sharma, Anima, Wong, Kasuen, Zhang, Junyu, Matlock, Elizabeth F., Rogers, Lowery, ...

The human T-cell lymphotropic virus type 1 (HTLV-1) infects and transforms CD4+ lymphocytes and causes adult T-cell leukemia/lymphoma (ATLL), an aggressive lymphoproliferative disease that is often...