Ishimoto, Hiroshi, Mukae, Hiroshi, Sakamoto, Noriho, Amenomori, Misato, Kitazaki, Takeshi, Imamura, Yoshifumi, ...
Objectives Mucus hypersecretion is a prominent feature in patients with chronic respiratory tract infections such as cystic fibrosis and diffuse panbronchiolitis, and the clinical effectiveness of...
Yanagi, Shigehisa, Ashitani, Jun-ichi, Ishimoto, Hiroshi, Date, Yukari, Mukae, Hiroshi, Chino, Naoyoshi, ...
Abstract Background Human β-defensin-4 (hBD-4), a new member of the β-defensin family, was discovered by an analysis of the genomic sequence. The objective of this study was to clarify hBD-4...
G-protein gamma subunit 1 is required for sugar reception in Drosophila
Ishimoto, Hiroshi, Takahashi, Kuniaki, Ueda, Ryu, Tanimura, Teiichi
Though G-proteins have been implicated in the primary step of taste signal transduction, no direct demonstration has been done in insects. We show here that a G-protein gamma subunit, Gγ1, is...
Molecular clearance of ataxin-3 is regulated by a mammalian E4
Matsumoto, Masaki, Yada, Masayoshi, Hatakeyama, Shigetsugu, Ishimoto, Hiroshi, Tanimura, Teiichi, Tsuji, Shoji, ...
Insoluble aggregates of polyglutamine-containing proteins are usually conjugated with ubiquitin in neurons of individuals with polyglutamine diseases. We now show that ataxin-3, in which the abnormal...
G-protein gamma subunit 1 is required for sugar reception in Drosophila
Ishimoto, Hiroshi, Takahashi, Kuniaki, Ueda, Ryu, Tanimura, Teiichi
Correction to: The EMBO Journal (2005) 24, 3259–3265. doi:10.1038/sj.emboj.7600796
Isolation of human β-defensin-4 in lung tissue and its increase in lower respiratory tract infection
Yanagi, Shigehisa, Ashitani, Jun-ichi, Ishimoto, Hiroshi, Date, Yukari, Mukae, Hiroshi, Chino, Naoyoshi, ...
G-protein gamma subunit 1 is required for sugar reception in Drosophila
Ishimoto, Hiroshi, Takahashi, Kuniaki, Ueda, Ryu, Tanimura, Teiichi
Though G-proteins have been implicated in the primary step of taste signal transduction, no direct demonstration has been done in insects. We show here that a G-protein gamma subunit, Gγ1, is...
Molecular clearance of ataxin-3 is regulated by a mammalian E4
Matsumoto, Masaki, Yada, Masayoshi, Hatakeyama, Shigetsugu, Ishimoto, Hiroshi, Tanimura, Teiichi, Tsuji, Shoji, ...
Insoluble aggregates of polyglutamine-containing proteins are usually conjugated with ubiquitin in neurons of individuals with polyglutamine diseases. We now show that ataxin-3, in which the abnormal...
G-protein gamma subunit 1 is required for sugar reception in Drosophila
Ishimoto, Hiroshi, Takahashi, Kuniaki, Ueda, Ryu, Tanimura, Teiichi
Correction to: The EMBO Journal (2005) 24, 3259–3265. doi:10.1038/sj.emboj.7600796
Isolation of human β-defensin-4 in lung tissue and its increase in lower respiratory tract infection
Yanagi, Shigehisa, Ashitani, Jun-ichi, Ishimoto, Hiroshi, Date, Yukari, Mukae, Hiroshi, Chino, Naoyoshi, ...
Kasuya, Junko, Ishimoto, Hiroshi, Kitamoto, Toshihiro
The fruit fly Drosophila melanogaster is an excellent model organism to identify genes and genetic pathways important for learning and memory. However, its small size makes surgical treatment and...
Ishimoto, Hiroshi, Sakai, Takaomi, Kitamoto, Toshihiro
Improved survival is likely linked to the ability to generate stable memories of significant experiences. Considerable evidence in humans and mammalian model animals shows that steroid hormones,...