Hiroshi Kobayashi

Temperature Measurement of Detonation Using UV-Absorption of O2, (9999)

Tsuboi,Takao, Egawa,Makoto, Kobayashi,Hiroshi, Hirose,Tsuneo, Kamei,Masaki

Temperature-dependent molar extinction coefficients of O2 were measured behind reflected shock waves. Using this temperature dependence of the molar extinction coefficients, the overall temperature...

Dust ring formation due to sublimation of dust grains drifting radially inward by the Poynting-Robertson drag: An analytical model (2009)

Kobayashi, Hiroshi, Watanabe, Sei-ichiro, Kimura, Hiroshi, Yamamoto, Tetsuo

Dust particles exposed to the stellar radiation and wind drift radially inward by the Poynting-Robertson (P-R) drag and pile up at the zone where they begin to sublime substantially. The reason they...

Expression of excess receptors and negative feedback control of signal pathways are required for rapid activation and prompt cessation of signal transduction (2009)

Kobayashi, Hiroshi, Azuma, Ryuzo, Yasunaga, Takuo

Abstract Background Cellular signal transduction is initiated by the binding of extracellular ligands to membrane receptors. Receptors are often expressed in excess, and cells are activated when a...

Comet 9P/Tempel 1: Interpretation with the Deep Impact Results (2007)

Yamamoto, Satoru, Kimura, Hiroshi, Zubko, Evgenij, Kobayashi, Hiroshi, Wada, Koji, Ishiguro, Masateru, ...

According to our common understandings, the original surface of a short-period comet nucleus has been lost by sublimation processes during its close approaches to the Sun. Sublimation results in the...

Which is the Better Pathological Prognostic Factor, the Nottingham Histological Grade or the Japanese Nuclear Grade? A Large Scale Study with a Long-term Follow-up (2007)

Otsuki, Yoshiro, Shimizu, Shin-ichi, Suwa, Kaori, Yoshida, Masayuki, Kanzaki, Masao, Kobayashi, Hiroshi

Background We compared the Nottingham histological grade (H-grade) and the Japanese nuclear grade (N-grade) to select the better prognostic factor for breast cancers. Methods The series included...

Alternative methods to evaluate the protective ability of sunscreen against photo-genotoxicity (2007)

Toyoshima, Megumi, Hosoda, Kanako, Hanamura, Miho, Okamoto, Keinosuke, Kobayashi, Hiroshi, Negishi, Tomoe

Numerous epidemiological investigations show that sunlight is carcinogenic to humans and that the use of sunscreen may be effective in decreasing the risk of skin cancer. The biological activity of a...

Comminution of logging residues with a tub grinder: Calculation of productivity and procurement cost of wood chips (2006)

Yoshioka, Takuyuki, Sakurai, Rin, Aruga, Kazuhiro, Nitami, Toshio, Sakai, Hideo, Kobayashi, Hiroshi

An experiment on comminution of logging residues with a tub grinder was carried out in order to calculate the productivity and procurement cost of wood chips. At the investigated site, the tub...

Particle simulation approach for subcellular dynamics and interactions of biological molecules (2006)

Azuma, Ryuzo, Kitagawa, Tetsuji, Kobayashi, Hiroshi, Konagaya, Akihiko

Abstract Background Spatio-temporal dynamics within cells can now be visualized at appropriate resolution, due to the advances in molecular imaging technologies. Even single-particle tracking (SPT)...

Comminution of logging residues with a tub grinder: Calculation of productivity and procurement cost of wood chips (2006)

Takuyuki Yoshioka, Rin Sakurai, Kazuhiro Aruga, Toshio Nitami, Hideo Sakai, Hiroshi Kobayashi

An experiment on comminution of logging residues with a tub grinder was carried out in order to calculate the productivity and procurement cost of wood chips. At the investigated site, the tub...

Development of face robot for emotional communication between human and robot (2006)

Takuya Hashimoto, Sachio Hiramatsu, Hiroshi Kobayashi

Abstract- The purpose of this study is to develop the interactive communication system that communicate with human beings emotionally such as a human-friendly robot in an environment where human and...

The Whole-body Vibration Evaluation Criteria of Forestry Machines (2004)

OH, Jae-Heun, PARK, Bum-Jin, ARUGA, Kazuhiro, NITAMI, Toshio, CHA, Du-Song, KOBAYASHI, Hiroshi

Ride vibration is a problem in forestry machines that can cause both injuries and discomfort to the operator. In order to evaluate forestry machine design with improved ride characteristics, it is...

A Case of Primary Plasma Cell Leukemia with Hairy-cell Morphology and Lambda-type Bence-Jones Protein. Immunohistochemical and Molecular Analysis (2003)

Tanioka, Fumihiko, Tamashima, Sadahiro, Shimizu, Shin-ichi, Kobayashi, Hiroshi, Kobayashi, Yukio, Sugimura, Haruhiko

A case of primary plasma cell leukemia with hairy-cell morphology and lambda-type Bence–Jones protein is reported. Most of the atypical cells in the peripheral blood of this case were small...

CYP2A6 gene deletion reduces oral cancer risk in betel quid chewers in Sri Lanka (2002)

Topcu, Zeki, Chiba, Itsuo, Fujieda, Masaki, Shibata, Toshiyuki, Ariyoshi, Noritaka, Yamazaki, Hiroshi, ...

We investigated the relationship between inter-individual difference in CYP2A6 genotype and susceptibility to oral cancer among habitual betel quid chewers in a Sri Lanka population. A total of 286...

トリチルカチオン生成反応に及ぼすリチウムイオンの求電子反応性の定量化 (2001)

池田, 慎哉, 小林, 宏, 園田, 高明, 聶, 進, 苑田, 晃成, ヤグポルスキー, ユーリー・A, ...

A trityl cation was generated from the reactions of trityl chloride and trityl alcohol with alkaline salt catalysts in weakly coordinating dichloromethane. The generated trityl cation was monitored...

The Effects of a Stellar Encounter on a Planetesimal Disk (2001)

Kobayashi, Hiroshi, Ida, Shigeru

We investigate the effects of a passing stellar encounter on a planetesimal disk through analytical calculations and numerical simulations, and derive the boundary radius ($a_{\rm planet}$) outside...

Human myometrial cells in culture express specific binding sites for urinary trypsin inhibitor (2000)

Kobayashi, Hiroshi, Hirashima, Yasuyuki, Terao, Toshihiko

Urinary trypsin inhibitor (UTI), which is present in amniotic fluid, prevents uterine contractility during pregnancy possibly via specific binding protein mechanisms. To test for the presence of UTI...

Urinary trypsin inhibitor down-regulates hyaluronic acid fragment-induced prostanoid release in cultured human amnion cells by inhibiting cyclo-oxygenase-2 expression (1999)

Kobayashi, Hiroshi, Sun, Guang Wei, Terao, Toshihiko

We postulated that urinary trypsin inhibitor (UTI), a Kunitz-type protease inhibitor, may inhibit low molecular weight hyaluronic acid (HA) fragment-induced prostanoid release and de-novo expression...

Role of Coccoliths in the Utilization of Inorganic Carbon by a Marine Unicellular Coccolithophorid, Emiliania huxleyi: a Survey Using Intact Cells and Protoplasts (1996)

Sekino, Keisuke, Kobayashi, Hiroshi, Shiraiwa, Yoshihiro

The utilization of inorganic carbon and role of the coccoliths were investigated in intact cells and protoplasts of a marine unicellular calcareous alga, Emiliania huxleyi. Protoplasts with high...

Synthesis, Lipophilicity, and Stability of Tetrakis (pentafluorophenyl) borate (FTPB) Anion under Highly Acidic Conditions in Comparison with Those of Tetrakis (3,5-bis (trifluoromethyl) phenyl) borate (TFPB) Anion (1995)

Isshiki, Minoru, Kobayashi, Hiroshi, Sonoda, Takaaki, 一色, 実, 小林, 宏, 園田, 高明, ...

An improved synthetic method for tetramethylammonium FTPB by a metal-halogen exchange reaction of pentafluorophenyl bromide with magnesium in the presence of a catalytic amount of butyl bromide and...

Synthesis and Properties of Poly ((Perfluoroalkyl) sulfonyl) amides and Methanide Ions as New Types of Anionic Phase-Transfer Catalysts in Azo Coupling Reactions (1995)

Kobayashi, Hiroshi, Meyer Zu Duttingdorf, Hans-Dieter, Nie, Jin, Sonoda, Takaaki, 小林, 宏, 聶, 進, ...

A series of lithium salts of bis ((perfluoroalkyl) sulfonyl) amides (1) with different chain lengths of perfluoroalkyl group and tris ((trifluoromethyl) sulfonyl) methanide (TTM) were prepared. The...

Development of Free Neuromasts with Special Reference to Sensory Polarity in Larvae of the Willow Shiner, Gnathopogon elongatus caerulescens (Teleostei, Cyprinidae) (1995)

Yukinori Mukai, Hiroshi Kobayashi

To find how larval fish sense mechanical stimuli via their free neuromasts, we examined morphological changes in free neuromasts in the larval willow shiner, Gnathopogon elongatus caerulescens. Free...

TFPB塩の溶液化学 : 裸のアルカリ金属イオンの親電子反応性について (1993)

小林, 宏, 藤木, 寛治, 柳楽, 明久, 聶, 進, 苑田, 晃成, 園田, 高明, ...

The electrophilicity of highly desolvated naked alkali metal ions ionpaired with tetrakis(3, 5-bis(trifluoromethy)phenyl)borate (TFPB) anion in nonpolar organic solvents was investigated in the C-C...

Syntheses of Some Arylazospiropyrans (1993)

Kobayashi, Hiroshi, Sonoda, Akinari, Sonoda, Takaaki, 小林, 宏, 苑田, 晃成, 園田, 高明, ...

The 6-(4-nitrophenylazo)-, 5'-chloro-6-(4-nitrophenylazo)-, and 5'-(4-fluorophenylazo)-derivatives of 1',3',3'-trimethylspiro[2H-1-benzopyran-2,2'-indoline] were synthesized and their structures were...

高次機能発現のための触媒設計 : ポリフルオロ置換ホウ素アート錯体の高脂溶性を利用する触媒効果 (1990)

小林, 宏, Kobayashi, Hiroshi, コバヤシ, ヒロシ

The article describes the molecular design of anionic phase transfer catalysts, which function as cationic-reagent carrier in hydrophobic organic media. Tetraphenyl-boron ate-complexes modified with...

Maintenance of a Neutral Cytoplasmic pH Is Not Obligatory for Growth of Escherichia coli and Streptococcus faecalis at an Alkaline pH (1990)

Mugikura, Shigeru, Nishikawa, Masuhiro, Igarashi, Kazuei, Kobayashi, Hiroshi

Both Escherichia coli and Streptococcus faecalis grew in an alkaline medium containing 100 μM carbonyl cyanide m-chlorophenylhydrazone (CCCP). Our data suggested that CCCP functioned as a...

Profitable Logging Operation System in Thinning with a Truck-Crane (1990)

KOBAYASHI, Hiroshi, ONO, Masamichi, NITAMI, Toshio, MINAMIKATA, Yasushi, TAKAHASHI, Yasuo, KAWAHARA, Shigeru, ...

北海道演習林のヨーロッパトウヒの人工林において平均傾斜20度前後の試験地を設定し,トラッククレーンによって搬出作業を行った。集材作業は,...

Effect of Polyamines on Mitochondrial F1-ATPase Catalyzed Reactions (1989)

Igarashi, Kazuei, Kashiwagi, Keiko, Kobayashi, Hiroshi, Ohnishi, Reiko, Kakegawa, Tomohito, Nagasu, Atsuko, ...

The effect of polyamines on F1 -ATPase catalyzed reactions has been studied through the use of submitochondrial particles and F1 -ATPase. ATP degradation catalyzed by submitochon-drial particles and...

Fluorinated Tetraarylborates as Anionic Phase-transfer Catalysts : An Example of Molecular Design of Functional Fluoroaromatics (1988)

Ichikawa, Junji, Kobayashi, Hiroshi, Sonoda, Takaaki, 市川, 淳士, 小林, 宏, 園田, 高明, ...

Tetrakis [3,5-bis (trifluoromethyl) phenyl] borate (TFPB), a highly lipophilic fluoroaromatic borate ion which is remarkably stable under acid and oxidative conditions, was designed as an anionic...

Metabolic predisposition of a novel mutant (LEC rats) to hereditary hepatitis and hepatoma: alterations of the drug metabolizing enzymes (1988)

Sugiyama, Toshihiro, Takeichi, Noritoshi, Kobayashi, Hiroshi, Yoshida, Michihiro C., Sasaki, Motomichi, Taniguchi, Naoyuki

Previously we established that ‘LEC rats’ have displayed spontaneous fulminant hepatitis with severe jaundice, which progressed to liver cancer, and a single autosomal recessive gene is...

Some lipophilic pyridylpyridinium tetrakis [3, 5-bis (trifluoromethyl) phenyl] borates as catalytic electron mediators (1987)

Shimizu, Tomonobu, Takuma, Keisuke, Sonoda, Takaaki, Kobayashi, Hiroshi, 園田, 高明, 小林, 宏, ...

1-Butyl-4-(4-pyridyl) pyridinium bromide, 1, 3-bis [4-(4-pyridyl) pyridinio] propane dibromide, and 1, 8-bis [4-(4-pyridyl) pyridiniomethyl] naphthalene dibromide were prepared. Their redox...

Synergistic Effects of the Myc and Ras Oncogenes on Ganglioside Synthesis by BALB/c 3T3 Fibroblasts1 (1986)

TAKIMOTO, Masato, HIRAKAWA, Tadashi, ODCAWA, Tsuneyuki, NAIKI, Masahani, MTYOSHI, Ichirou, KOBAYASHI, Hiroshi

The effects of oncogene activation on glycosphingolipid (GSL) synthesis by a mouse fibroblast clonal cell line were studied. A transfectant that expressed the activated ras gene showed a definite...

Detection of Tumor-Associated Antigens of Osteosarcoma in Humans by the Mixed Lymphocyte Tumor Cell Culture Assay (1979)

MINAMI, AKIO, HAYAKAWA, KUNIO, OKAYASU, TAKESHI, SASAKI, TETSUTO, YAMAWAKI, SHINYA, KOBAYASHI, HIROSHI

Tumor-associated antigens of human osteosarcoma cells were studied by the mixed lymphocyte tumor cell culture (MLTC) assay. Peripheral blood lymphocytes from patients with osteosarcomas reacted with...

Studies on the Turnovers In Vivo of Adenosine Di- and Triphosphates in a Coupling Factor of Escherichia coil (1977)

MAEDA, Masatomo, KOBAYASHI, Hiroshi, FUTAI, Masamitsu, ANRAKU, Yasuhiro

The metabolic stabilities of bound adenine nucleotides in a membrane-bound ATPase (EF1) [EC 3.6.1.3] of Escherichia coil were studied by estimating their rates of turnover in vivo. Two-thirds of the...

Membrane-Bound Adenosine Triphosphatase of Escherichia coli: III. Effects of Sodium Azide on the Enzyme Functions (1977)

KOBAYASHI, Hiroshi, MAEDA, Masatomo, ANRAKU, Yasuhiro

Sodium azide and diphenyl phosphorazidate (DPPA) inhibited purified membrane-bound ATPase [coupling factor of oxidative phosphorylation; EC 3.6.1.3] of Escherichia coli noncompetitively with K1...

Transport of Sugars and Amino Acids in Bacteria: X. Sources of Energy and Energy Coupling Reactions of the Active Transport Systems for Isoleucine and Proline in E. coii (1974)

KOBAYASHI, Hiroshi, KIN, Emi, ANRAKU, Yasuhiro

The sources of energy and energy coupling reactions of the active transport systems for isoleucine and proline in Escherichia coli cells were studied. It was concluded that the isoleucine transport...

Membrane-bound Adenosinetriphosphatase of Escherichia coli: II. Physicochemical Properties of the Enzyme (1974)

KOBAYASHI, Hiroshi, ANRAKU, Yasuhiro

Membrane-bound adenosinetriphosphatase [ATPase,** EC 3.6.1.3] of Escherichia coli was purified on a large scale. The purified ATPase contained 0.72 μg of total phosphorus per mg of protein. Less...

Transport of Sugars and Amino Acids in Bacteria: VII. Characterization of the Reaction of Restoration of Active Transport Mediated by Binding Protein (1973)

ANRAKU, Yasuhiro, KOBAYASHI, Hiroshi, AMANUMA, Hiroshi, YAMAGUCHI, Akihito

Studies were made on the protein factors released by osmotic shock, which were active in restoration of active transport in osmotically shocked cells of Escherichia coli. Binding proteins were...

Membrane-bound Adenosine Triphosphatase of Escherichia coli: I. Partial Purification and Properties (1972)

KOBAYASHI, Hiroshi, ANRAKU, Yasuhiro

A simple procedure was developed for releasing membrane-bound adenosine triphosphatase [EC 3. 6. 1. 3] from the membrane fraction of Escherichia coli. This involved washing the fraction with dilute...

Expression of Outer Membrane Proteins in Escherichia coli Growing at Acid pH

Sato, Mikiko, Machida, Kazuhiro, Arikado, Eri, Saito, Hiromi, Kakegawa, Tomohito, Kobayashi, Hiroshi

It is generally accepted for Escherichia coli that (i) the level of OmpC increases with increased osmolarity when cells are growing in neutral and alkaline media, whereas the level of OmpF decreases...

Membrane-Bound ATPase Contributes to Hop Resistance of Lactobacillus brevis

Sakamoto, Kanta, Van Veen, H. W., Saito, Hiromi, Kobayashi, Hiroshi, Konings, Wil N.

The activity of the membrane-bound H+-ATPase of the beer spoilage bacterium Lactobacillus brevis ABBC45 increased upon adaptation to bacteriostatic hop compounds. The ATPase activity was optimal...

Bikunin Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor Alpha Induction in Macrophages

Matsuzaki, Hidenori, Kobayashi, Hiroshi, Yagyu, Tatsuo, Wakahara, Kiyoshi, Kondo, Toshiharu, Kurita, Noriyuki, ...

Bikunin, a Kunitz-type protease inhibitor, exhibits anti-inflammatory activity in protection against cancer and inflammation. To investigate the molecular mechanism of this inhibition, we analyzed...

Expression of Outer Membrane Proteins in Escherichia coli Growing at Acid pH

Sato, Mikiko, Machida, Kazuhiro, Arikado, Eri, Saito, Hiromi, Kakegawa, Tomohito, Kobayashi, Hiroshi

It is generally accepted for Escherichia coli that (i) the level of OmpC increases with increased osmolarity when cells are growing in neutral and alkaline media, whereas the level of OmpF decreases...

Membrane-Bound ATPase Contributes to Hop Resistance of Lactobacillus brevis

Sakamoto, Kanta, Van Veen, H. W., Saito, Hiromi, Kobayashi, Hiroshi, Konings, Wil N.

The activity of the membrane-bound H+-ATPase of the beer spoilage bacterium Lactobacillus brevis ABBC45 increased upon adaptation to bacteriostatic hop compounds. The ATPase activity was optimal...

Bikunin Inhibits Lipopolysaccharide-Induced Tumor Necrosis Factor Alpha Induction in Macrophages

Matsuzaki, Hidenori, Kobayashi, Hiroshi, Yagyu, Tatsuo, Wakahara, Kiyoshi, Kondo, Toshiharu, Kurita, Noriyuki, ...

Bikunin, a Kunitz-type protease inhibitor, exhibits anti-inflammatory activity in protection against cancer and inflammation. To investigate the molecular mechanism of this inhibition, we analyzed...

RNA expression in a cartilaginous fish cell line reveals ancient 3′ noncoding regions highly conserved in vertebrates

Forest, David, Nishikawa, Ryuhei, Kobayashi, Hiroshi, Parton, Angela, Bayne, Christopher J., Barnes, David W.

We have established a cartilaginous fish cell line [Squalus acanthias embryo cell line (SAE)], a mesenchymal stem cell line derived from the embryo of an elasmobranch, the spiny dogfish shark S....

Copper Proteins and Oxygen : Correlations between structure and function of the copper oxidases

Frieden, Earl, Osaki, Shigemasa, Kobayashi, Hiroshi

A comprehensive survey of the interaction of the copper proteins and oxygen is presented including a correlation of structure, function, and other properties of the known copper oxidases and of...

Staphylococcus aureus MazF Specifically Cleaves a Pentad Sequence, UACAU, Which Is Unusually Abundant in the mRNA for Pathogenic Adhesive Factor SraP ▿

Zhu, Ling, Inoue, Koichi, Yoshizumi, Satoshi, Kobayashi, Hiroshi, Zhang, Yonglong, Ouyang, Ming, ...

Escherichia coli mRNA interferases, such as MazF and ChpBK, are sequence-specific endoribonucleases encoded by toxin-antitoxin (TA) systems present in its genome. A MazF homologue in Staphylococcus...