Hiroshi Shimada

Effect of obesity on intraoperative bleeding volume in open gastrectomy with D2 lymph-node dissection for gastric cancer (2008)

Makino, Hirochika, Kunisaki, Chikara, Akiyama, Hirotoshi, Ono, Hidetaka A, Kosaka, Takashi, Takagawa, Ryo, ...

Abstract Background To investigate the effect of obesity on open gastrectomy with D2 lymph-node dissection. Methods Between January 2005 and March 2007, 100 patients with preoperatively diagnosed...

Spin Polarization and Magneto-Coulomb Oscillations in Ferromagnetic Single Electron Devices (1998)

Ono, Keiji, Shimada, Hiroshi, Ootuka, Youiti

The magneto-Coulomb oscillation, the single electron repopulation induced by external magnetic field, observed in a ferromagnetic single electron transistor is further examined in various...

Magneto-Coulomb Oscillation in Ferromagnetic Single Electron Transistors (1997)

Shimada, Hiroshi, Ono, Keiji, Ootuka, Youiti

The mechanism of the magneto-Coulomb oscillation in ferromagnetic single electron transistors (SET's) is theoretically considered. Variations in the chemical potentials of the conduction electrons in...

Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases

Yang, Meng, Baranov, Eugene, Jiang, Ping, Sun, Fang-Xian, Li, Xiao-Ming, Li, Lingna, ...

We have imaged, in real time, fluorescent tumors growing and metastasizing in live mice. The whole-body optical imaging system is external and noninvasive. It affords unprecedented continuous visual...

Governing step of metastasis visualized in vitro

Chishima, Takashi, Yang, Meng, Miyagi, Yohei, Li, Lingna, Tan, Yuying, Baranov, Eugene, ...

Metastasis is the ultimate life-threatening stage of cancer. The lack of accurate model systems thwarted studies of the metastatic cell’s basic biology. To follow continuously the succeeding stages...

Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: Finding of a lipase motif and the induction by methyl jasmonate

Tsuchiya, Tohru, Ohta, Hiroyuki, Okawa, Katsuya, Iwamatsu, Akihiro, Shimada, Hiroshi, Masuda, Tatsuru, ...

Chlorophyllase (Chlase) is the first enzyme involved in chlorophyll (Chl) degradation and catalyzes the hydrolysis of ester bond to yield chlorophyllide and phytol. In the present study, we isolated...

Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays

Miki, Rika, Kadota, Koji, Bono, Hidemasa, Mizuno, Yosuke, Tomaru, Yasuhiro, Carninci, Piero, ...

We have systematically characterized gene expression patterns in 49 adult and embryonic mouse tissues by using cDNA microarrays with 18,816 mouse cDNAs. Cluster analysis defined sets of genes that...

Two types of MGDG synthase genes, found widely in both 16:3 and 18:3 plants, differentially mediate galactolipid syntheses in photosynthetic and nonphotosynthetic tissues in Arabidopsis thaliana

Awai, Koichiro, Maréchal, Eric, Block, Maryse A., Brun, Delphine, Masuda, Tatsuru, Shimada, Hiroshi, ...

In Arabidopsis, monogalactosyldiacylglycerol (MGDG) is synthesized by a multigenic family of MGDG synthases consisting of two types of enzymes differing in their N-terminal portion: type A (atMGD1)...

Production of the Carotenoids Lycopene, β-Carotene, and Astaxanthin in the Food Yeast Candida utilis

Miura, Yutaka, Kondo, Keiji, Saito, Toshiko, Shimada, Hiroshi, Fraser, Paul D., Misawa, Norihiko

The food-grade yeast Candida utilis has been engineered to confer a novel biosynthetic pathway for the production of carotenoids such as lycopene, β-carotene, and astaxanthin. The exogenous...

Increased Carotenoid Production by the Food Yeast Candida utilis through Metabolic Engineering of the Isoprenoid Pathway

Shimada, Hiroshi, Kondo, Keiji, Fraser, Paul D., Miura, Yutaka, Saito, Toshiko, Misawa, Norihiko

The yeast Candida utilis does not possess an endogenous biochemical pathway for the synthesis of carotenoids. The central isoprenoid pathway concerned with the synthesis of prenyl lipids is present...

Whole-body optical imaging of green fluorescent protein-expressing tumors and metastases

Yang, Meng, Baranov, Eugene, Jiang, Ping, Sun, Fang-Xian, Li, Xiao-Ming, Li, Lingna, ...

We have imaged, in real time, fluorescent tumors growing and metastasizing in live mice. The whole-body optical imaging system is external and noninvasive. It affords unprecedented continuous visual...

Governing step of metastasis visualized in vitro

Chishima, Takashi, Yang, Meng, Miyagi, Yohei, Li, Lingna, Tan, Yuying, Baranov, Eugene, ...

Metastasis is the ultimate life-threatening stage of cancer. The lack of accurate model systems thwarted studies of the metastatic cell’s basic biology. To follow continuously the succeeding stages...

Cloning of chlorophyllase, the key enzyme in chlorophyll degradation: Finding of a lipase motif and the induction by methyl jasmonate

Tsuchiya, Tohru, Ohta, Hiroyuki, Okawa, Katsuya, Iwamatsu, Akihiro, Shimada, Hiroshi, Masuda, Tatsuru, ...

Chlorophyllase (Chlase) is the first enzyme involved in chlorophyll (Chl) degradation and catalyzes the hydrolysis of ester bond to yield chlorophyllide and phytol. In the present study, we isolated...

Delineating developmental and metabolic pathways in vivo by expression profiling using the RIKEN set of 18,816 full-length enriched mouse cDNA arrays

Miki, Rika, Kadota, Koji, Bono, Hidemasa, Mizuno, Yosuke, Tomaru, Yasuhiro, Carninci, Piero, ...

We have systematically characterized gene expression patterns in 49 adult and embryonic mouse tissues by using cDNA microarrays with 18,816 mouse cDNAs. Cluster analysis defined sets of genes that...

Two types of MGDG synthase genes, found widely in both 16:3 and 18:3 plants, differentially mediate galactolipid syntheses in photosynthetic and nonphotosynthetic tissues in Arabidopsis thaliana

Awai, Koichiro, Maréchal, Eric, Block, Maryse A., Brun, Delphine, Masuda, Tatsuru, Shimada, Hiroshi, ...

In Arabidopsis, monogalactosyldiacylglycerol (MGDG) is synthesized by a multigenic family of MGDG synthases consisting of two types of enzymes differing in their N-terminal portion: type A (atMGD1)...

Production of the Carotenoids Lycopene, β-Carotene, and Astaxanthin in the Food Yeast Candida utilis

Miura, Yutaka, Kondo, Keiji, Saito, Toshiko, Shimada, Hiroshi, Fraser, Paul D., Misawa, Norihiko

The food-grade yeast Candida utilis has been engineered to confer a novel biosynthetic pathway for the production of carotenoids such as lycopene, β-carotene, and astaxanthin. The exogenous...

Increased Carotenoid Production by the Food Yeast Candida utilis through Metabolic Engineering of the Isoprenoid Pathway

Shimada, Hiroshi, Kondo, Keiji, Fraser, Paul D., Miura, Yutaka, Saito, Toshiko, Misawa, Norihiko

The yeast Candida utilis does not possess an endogenous biochemical pathway for the synthesis of carotenoids. The central isoprenoid pathway concerned with the synthesis of prenyl lipids is present...

果樹花粉の発芽におよぼす核酸関連物質の影響 : I. ナシ花粉の発芽におよぼす核酸関連物質の影響

大野, 正夫, オオノ, マサオ, Ōno, Masao, OHNO, Masao, 林, 修一郎, ハヤシ, シュウイチロウ, ...

1.核酸関連物質としてのアデノシン, シチジン, グワノシソ, イノシソ, ウリジン, 5'AMP-2Na, 5'CMP-2Na, 5'GMP-2Na,...

果樹花粉の発芽におよぼす核酸関連物質の影響 : I. ナシ花粉の発芽におよぼす核酸関連物質の影響

大野, 正夫, オオノ, マサオ, Ōno, Masao, OHNO, Masao, 林, 修一郎, ハヤシ, シュウイチロウ, ...

1.核酸関連物質としてのアデノシン, シチジン, グワノシソ, イノシソ, ウリジン, 5'AMP-2Na, 5'CMP-2Na, 5'GMP-2Na,...

Management of Massive Arterial Hemorrhage After Pancreatobiliary Surgery: Does Embolotherapy Contribute to Successful Outcome?

Fujii, Yoshiro, Shimada, Hiroshi, Endo, Itaru, Yoshida, Ken-ichi, Matsuo, Ken-ichi, Takeda, Kazuhisa, ...

Massive arterial hemorrhage is, although unusual, a life-threatening complication of major pancreatobiliary surgery. Records of 351 patients who underwent major surgery for malignant pancreatobiliary...

Outcomes of Adult-to-Adult Living Donor Liver Transplantation: A Single Institution's Experience With 335 Consecutive Cases

Morioka, Daisuke, Egawa, Hiroto, Kasahara, Mureo, Ito, Takashi, Haga, Hironori, Takada, Yasutsugu, ...

Surgical outcomes of adult-to-adult living donor liver transplantation (AALDLT) donors were significantly affected by the graft type and accumulation of case experience. Survival outcomes of AALDLT...

Activities of Daily Living and Quality of Life of Elderly Patients After Elective Surgery for Gastric and Colorectal Cancers

Amemiya, Takeshi, Oda, Koji, Ando, Masahiko, Kawamura, Takashi, Kitagawa, Yuichi, Okawa, Yayoi, ...

Radical surgical treatment should be considered for elderly patients 75 years old or older with gastric or colorectal cancer, as only a few patients who underwent radical surgery showed a protracted...

Arabidopsis Cotyledon-Specific Chloroplast Biogenesis Factor CYO1 Is a Protein Disulfide Isomerase[W]

Shimada, Hiroshi, Mochizuki, Mariko, Ogura, Kan, Froehlich, John E., Osteryoung, Katherine W., Shirano, Yumiko, ...

Chloroplast development in cotyledons differs in a number of ways from that in true leaves, but the cotyledon-specific program of chloroplast biogenesis has not been clarified. The cyo1 mutant in...