Development of Pair Monitor (2009)
Takubo, Yosuke, Ikeda, Hirokazu, Ito, Kazutoshi, Miyamoto, Akiya, Nagamine, Tadashi, Sasaki, Rei, ...
The pair monitor is a beam profile monitor at interaction point (IP) for the international linear collider (ILC). We have designed and developed the pair monitor as a silicon pixel sensor which is...
Yonemura, Masahito, Katsumata, Noriyuki, Hashimoto, Hironobu, Satake, Shoko, Kaneko, Masayuki, Kobayashi, Yuka, ...
Objective The aim of this study was to assess the non-inferiority of 1 mg to 3 mg granisetron (GRN) injection for the treatment of acute chemotherapy-induced nausea and vomiting (CINV) and to...
Ushiki, Atsuhito, Koizumi, Tomonobu, Kobayashi, Nobumitsu, Kanda, Shintarou, Yasuo, Masanori, Yamamoto, Hiroshi, ...
Somatic epidermal growth factor receptor (EGFR) mutations in exons 19 and 21 have been found in non-small cell lung cancer (NSCLC) and are associated with the therapeutic response to gefitinib in...
Sun, Li, Ishida, Tatsuro, Yasuda, Tomoyuki, Kojima, Yoko, Honjo, Tomoyuki, Yamamoto, Yasuhiko, ...
Aims Receptor for advanced glycation end products (RAGE) plays a pivotal role in the genesis of diabetic vascular diseases. To further explore the mechanisms underlying atherosclerosis under...
Efficient total syntheses of natural pterin glycosides: limipterin and tepidopterin (2008)
Hanaya, Tadashi, Baba, Hiroki, Toyota, Hiroki, Yamamoto, Hiroshi
The key, versatile precursors N-2-(N,N-dimethylaminomethylene)-1'-O-(4-methoxybenzyl)-3-[2-(4-nitrophenyl)ethyl]biopterin (29a) and its ciliapterin analog (29b) were prepared, respectively, from...
An efficient, one-pot synthesis of fosfomycin dialkyl esters from (R)-2-tosyloxypropanal (2008)
Hanaya, Tadashi, Nakamura, Yuichi, Yamamoto, Hiroshi
(R)-2-Tosyloxypropanal (4) was prepared from D-mannitol in a 7-step sequence (51% overall yield). Addition of dialkyl phosphonates to 4 in the presence of titanium isopropoxide and the subsequent...
Nishiyama, Takashi, Yamamoto, Hiroshi, Uchiumi, Toshio, Nakashima, Nobuhiko
The intergenic region-internal ribosome entry site (IGR-IRES) of dicistroviruses binds to 40S ribosomal subunits in the absence of eukaryotic initiation factors (eIFs). Although the conserved loop...
Lymphocyte cytotoxicity against allogeneic cultured cells in gynecologic malignancy. (2007)
Arata, Takiji, Momozaki, Fumitaka, Kazuta, Minoru, Yamamoto, Hiroshi, Sekiba, Kaoru
Peripheral blood lymphocytes from patients with gynecologic cancer were tested by micro-cytotoxicity assay against two types of allogeneic cultured cancer cell lines: squamous cell carcinoma and...
Computed tomographic arteriography in the diagnosis of hepatocellular carcinoma. (2007)
Ito, Toshio, Yamamoto, Hiroshi, Itoshima, Tatsuya, Ukida, Minoru, Ogawa, Hiromichi, Kitadai, Masahiro, ...
Computed tomographic arteriography (CTA) was performed in 30 patients with hepatocellular carcinoma (HCC). Detection of HCC by CTA was compared with that of conventional celiac or hepatic...
Shiota, Tetsuya, Watanabe, Akiharu, Itoshima, Tatsuya, Yamamoto, Hiroshi, Takahashi, Kenji, Nagashima, Hideo
Two cases of chronic unconjugated hyperbilirubinemia and marked retention of indocyanine green (ICG) are described. Since bilirubin uridine diphosphate (UDP)-glucuronyl transferase activities were...
Hidenori Koyama, Hiroshi Yamamoto, Yoshiki Nishizawa
Receptor for advanced glycation end-products (RAGE) is known to be involved in both micro- and macrovascular complications in diabetes. Among numerous truncated forms of RAGE recently described, the...
Nishiyama, Takashi, Yamamoto, Hiroshi, Uchiumi, Toshio, Nakashima, Nobuhiko
The intergenic region-internal ribosome entry site (IGR-IRES) of dicistroviruses binds to 40S ribosomal subunits in the absence of eukaryotic initiation factors (eIFs). Although the conserved loop...
On the principle of minimum growth rate in multiplicatively interacting stochastic processes (2006)
Fujihara, Akihiro, Ohtsuki, Toshiya, Yamamoto, Hiroshi
A method of moment inequalities is used to derive the principle of minimum growth rate in multiplicatively interacting stochastic processes(MISPs). When a value of a power-law exponent at the tail of...
Sunahori, Katsue, Yamamura, Masahiro, Yamana, Jiro, Takasugi, Kouji, Kawashima, Masanori, Yamamoto, Hiroshi, ...
Abstract S100A8 and S100A9, two Ca 2+ -binding proteins of the S100 family, are secreted as a heterodimeric complex (S100A8/A9) from neutrophils and monocytes/macrophages. Serum and synovial fluid...
Dissolution Kinetics of High Explosives Particles in a Saturated Sandy Soil (2006)
Morley, Matthew C., Yamamoto, Hiroshi, Clausen, Jay
Solid phase high explosive (HE) residues from munitions detonation may be a persistent source of soil and groundwater contamination at military training ranges. Saturated soil column tests were...
Inoue, Takamitsu, Satoh, Shigeru, Numakura, Kazuyuki, Saito, Mitsuru, Tsuchiya, Norihiko, Nanjo, Hiroshi, ...
Yamamoto, Hiroshi, Kato, Hideki, Shinzaki, Yuki, Horiguchi, Sayaka, Shikanai, Toshiharu, Hase, Toshiharu, ...
We tested the hypothesis that ferredoxin (Fd) limits the activity of cyclic electron flow around PSI (CEF-PSI) in vivo and that the relief of this limitation promotes the non-photochemical quenching...
Inoue, Takamitsu, Satoh, Shigeru, Numakura, Kazuyuki, Saito, Mitsuru, Tsuchiya, Norihiko, Nanjo, Hiroshi, ...
Yamamoto, Hiroshi, Kato, Hideki, Shinzaki, Yuki, Horiguchi, Sayaka, Shikanai, Toshiharu, Hase, Toshiharu, ...
We tested the hypothesis that ferredoxin (Fd) limits the activity of cyclic electron flow around PSI (CEF-PSI) in vivo and that the relief of this limitation promotes the non-photochemical quenching...
YAMAMOTO, Hiroshi, KAWAHARA, Kenji, TAKINE, Tetsuya, OIE, Yuji
Recent improvements in the performance of end-computers and networks have made it feasible to construct a grid system over the Internet. A grid environment consists of many computers, each having a...
Inoue, Takamitsu, Satoh, Shigeru, Numakura, Kazuyuki, Saito, Mitsuru, Tsuchiya, Norihiko, Nanjo, Hiroshi, ...
Log-normal distribution in growing systems with weighted multiplicative interactions (2005)
Fujihara, Akihiro, Tanimoto, Satoshi, Ohtsuki, Toshiya, Yamamoto, Hiroshi
Many-body stochastic processes with weighted multiplicative interactions are investigated analytically and numerically. An interaction rate between particles with quantities $x, y$ is controlled by a...
Asymptotic analysis of the model for distribution of high-tax payers (2005)
Yamamoto, Hiroshi, Ohtsuki, Toshiya, Fujihara, Akihiro, Tanimoto, Satoshi, Yamamoto, Keizo, Miyazima, Sasuke
The z-transform technique is used to investigate the model for distribution of high-tax payers, which is proposed by two of the authors (K. Y and S. M) and others. Our analysis shows an asymptotic...
日本中世訴訟制度における《裁許前誓約》 : 鎌倉幕府による濫訴対策の一側面 (2005)
山本, 弘, Yamamoto, Hiroshi, ヤマモト, ヒロシ
一 はじめに 二 打越請文 三 懸物押書 (1) 懸物押書に関する立法 (2) 懸物押書の事例 四 その他の《裁許前誓約》 (1) 所務沙汰請文 (2)...
Fujihara, Akihiro, Ohtsuki, Toshiya, Yamamoto, Hiroshi
Analytical and numerical studies on many-body stochastic processes with multiplicative interactions are reviewed. The method of moment relations is used to investigate effects of asymmetry and...
Fujihara, Akihiro, Ohtsuki, Toshiya, Yamamoto, Hiroshi
We consider stochastic processes where randomly chosen particles with positive quantities x, y (> 0) interact and exchange the quantities asymmetrically by the rule x' = c{(1-a) x + b y}, y' = d{a x...
EXPLORATION OF NEW CHEMOTHERAPEUTICS FOR INFECTIOUS DISEASES (2005)
Protomycin is a new antibiotic belonging to cycloheximide group with activities against Endameba hystolytica and saccharomyces, particularly resembling to streptimidone by Frohardt et. al. in Parke...
Miyake, Chikahiro, Horiguchi, Sayaka, Makino, Amane, Shinzaki, Yuki, Yamamoto, Hiroshi, Tomizawa, Ken-ichi
We tested the hypothesis that plants grown under high light intensity (HL-plants) had a large activity of cyclic electron flow around PSI (CEF-PSI) compared to plants grown under low light...
Miyake, Chikahiro, Horiguchi, Sayaka, Makino, Amane, Shinzaki, Yuki, Yamamoto, Hiroshi, Tomizawa, Ken-ichi
We tested the hypothesis that plants grown under high light intensity (HL-plants) had a large activity of cyclic electron flow around PSI (CEF-PSI) compared with plants grown under low light...
Compact and Low-Power-Consumption 40-Gbit/s, 1.55-{micro}m Electro-Absorption Modulators (2005)
ARIMOTO, Hideo, SHIMIZU, Jun-ichiro, KITATANI, Takeshi, SHINODA, Kazunori, TSUCHIYA, Tomonobu, SHIRAI, Masataka, ...
This paper describes 40-Gbit/s operation of 1.55-μm electro-absorption (EA) modulators applicable to compact and low-cost transmitters for very-short-reach (VSR) applications. We start by...
Miyake, Chikahiro, Horiguchi, Sayaka, Makino, Amane, Shinzaki, Yuki, Yamamoto, Hiroshi, Tomizawa, Ken-ichi
We tested the hypothesis that plants grown under high light intensity (HL-plants) had a large activity of cyclic electron flow around PSI (CEF-PSI) compared to plants grown under low light...
Wearable power assist device for hand grasping using pneumatic artificial rubber muscle (2004)
Noritsugu, Toshiro, Yamamoto, Hiroshi, Sasaki, Daisuke, Takaiwa, Masahiro
The purpose of this study is to develop a wearable power assist device for hand grasping in order to support activity of daily living (ADL) safely and easily. In this paper, the mechanism of the...
Wearable power assist device for hand grasping using pneumatic artificial rubber muscle (2004)
Noritsugu, Toshiro, Yamamoto, Hiroshi, Sasaki, Daisuke, Takaiwa, Masahiro
The purpose of this study is to develop a wearable power assist device for hand grasping in order to support activity of daily living (ADL) safely and easily. In this paper, the mechanism of the...
Yamamoto, Yasuhiko, Yonekura, Hideto, Sakurai, Shigeru, Tanaka, Nobushige, Hui, Li, Khin-Mar, Myint, ...
As is diabetes itself, diabetic vasculopathy is a multifactor disease. Studies conducted in this lab revealed advanced glycation endproducts (AGE) as the major environmental account for vascular cell...
Tokoyoda, Koji, Tsujikawa, Kazutake, Matsushita, Hiroaki, Ono, Yuichi, Hayashi, Tamon, Harada, Yohsuke, ...
The signal transduction of the cAMP/cAMP‐dependent protein kinase [protein kinase A (PKA)] pathway through multiple receptors is critical for many processes in all cell types. In...
Effects of Randomness on Power Law Tails in Multiplicatively Interacting Stochastic Processes (2003)
Ohtsuki, Toshiya, Fujihara, Akihiro, Yamamoto, Hiroshi
Effects of randomness on non-integer power law tails in multiplicatively interacting stochastic processes are investigated theoretically. Generally, randomness causes decrease of the exponent of...
Every non-trivial closed curve $C$ on a compact Riemann surface $R$ is freely homotopic to the $r$-fold iterate ${C_0}^r$ of some primitive closed geodesic $C_0$ on $R$. We call $r$ the multiplicity...
山本, 弘, Yamamoto, Hiroshi, ヤマモト, ヒロシ
１．はじめに ２．堺打越制度の立法と適用 (1)堺打越制度の立法 ①御成敗式目第三六条 ②鎌倉幕府追加法七六条 ③文法年中発給の関東御事...
Yamamoto, Hiroshi, Thys, Chantal, Kito, Morikazu
Platelet adhesion to damaged vessel wall and shear-induced platelet aggregation necessitate binding of the von Willebrand factor (VWF) A1 domain to platelet GPIbalpha. Blocking this interaction...
Interface Conduction between Conductive ReO3 Thin Films and NdBa2Cu3O6 Thin Film (2003)
Ohkubo, Manabu, Fukai, Kumiko, Matsuo, Kohji, Iwata, Nobuyuki, Yamamoto, Hiroshi
The Re oxide films were deposited on quartz glasses by RF reactive sputtering from a Re metal target. The lowest resistivity was observed in the film in-situ annealed at 200 deg. C in Ar atmosphere...
Data Dependent Circuit Design: A Case Study (2003)
Shoji Yamamoto, Shuichi Ichikawa, Hiroshi Yamamoto
Abstract. Data dependent circuits are logic circuits specialized to specific input data. They are smaller and faster than the original circuits, although they are not reusable and require circuit...
Nakahara, Ken, Yamamoto, Hiroshi, Miyake, Chikahiro, Yokota, Akiho
The whole genome sequence database for Synechocystis sp. PCC 6803 has revealed the presence of genes encoding class-I (CI) and class-II (CII) fructose-1,6-bisphosphate aldolases (FBAs) in this...
Nishiyama, Takashi, Yamamoto, Hiroshi, Shibuya, Norihiro, Hatakeyama, Yoshinori, Hachimori, Akira, Uchiumi, Toshio, ...
Plautia stali intestine virus (PSIV) has an internal ribosome entry site (IRES) at the intergenic region of the genome. The PSIV IRES initiates translation with glutamine rather than the universal...
The role of AGE-Rage system in the development of diabetic nephropathy in vivo (2002)
Yamamoto, Yasuhiko, Kato, Ichiro, Doi, Toshio, Yonekura, Hideto, Ohashi, Seiji, Takeuchi, Masayoshi, ...
Vascular complications are what eventually threaten the lives of diabetic patients. Here we show direct in vivo evidence that the interaction between advanced glycation end products (AGE), the...
Thesis (Ph. D.)--University of Texas at Austin, 2002.
Thesis (Ph. D.)--University of Texas at Austin, 2002.
Thesis (Ph. D.)--University of Texas at Austin, 2002.
Kawamori, Toshihiko, Uchiya, Naoaki, Nakatsugi, Seiichi, Watanabe, Kouji, Ohuchida, Shuichi, Yamamoto, Hiroshi, ...
Levels of prostaglandin E2 (PGE2) in human and rodent breast cancers are higher than surrounding normal tissues. PGE2 exhibits biological activity through binding to membrane receptors, EP1–4. The...
Delegation mechanism in agent-oriented framework for managing long-lived transaction (1999)
Yamamoto, Hiroshi, Guo, Yuntao, Suzuki, Koichiro, Watanabe, Toyohide
This paper addresses the long-lived transaction management paradigm based on workflows with a view to evaluating the un-exacutable works. In our 3-layer transaction model, each long-lived transaction...
Uemura, Koichi, Tokai, Hiroshi, Higuchi, Takashi, Murayama, Hiroshi, Yamamoto, Hiroshi, Enomoto, Yukito, ...
The biphasic reaction course, fallover, of carboxyla-tion catalysed by ribulose 1,5-bisphosphate carboxylase/ox-ygenase (RuBisCO) has been known as a characteristic of the enzyme from higher land...
Kitagawa, Yoshichika, Yamamoto, Hiroshi, Oritani, Takayuki
The rate of synthesis of abscisic acid (ABA) by the phytopathogenic fungus Cercospora cruenta was found to be increased 2.6-fold by water stress (0.5 M mannitol, 48 h). To characterize the oxidative...
Takeuchi, Tamotsu, Tamamoto, Tohru, Tamura, Hiroo, Yamamoto, Hiroshi, Takemori, T.
We previously reported that the nude mouse-derived splenic T cell clone, N-9F, exhibits a prollferative response to the SL10.3 thymic epithelial cell clone. In the present study we generated an...
Towards a Canonical Formalism of Field Theory on Discrete Spacetime (1993)
Yamamoto, Hiroshi, Hayashi, Akihisa, Hashimoto, Takaaki, Horibe, Minoru
It is shown that the difficulties in formulating the quantum field theory on discrete spacetime appear already in classical dynamics of one degree of freedom on discrete time. The difference equation...
Fukutomi, Takashi, Itabashi, Masayuki, Tsugane, Shoichiro, Yamamoto, Hiroshi, Nanasawa, Takeshi, Hirota, Teruyuki
Helix Pomatia (HPA) and carcinoembryonic antigen (CEA) staining were studied in 113 primary breast carcinomas, 63 metastatic lymph nodes and 10 resected local recurrences, using the...
SUGANUMA, Yoshiko, SHIMODE, Chieko, YAMAMOTO, Hiroshi
Complementary mating types (11 and IV) of Tetrahymena thermophila were mixed in various ratios to induce conjugation. Interactions that occurred during co-stimulation period, even in a numerical...
A Case of Neurogenic Sarcoma of the Stomach (1981)
MIZUTA, MASAO, NAKAJIMA, TAKASHI, ITABASHI, MASAYUKI, HIROTA, TERUYUKI, YAMAMOTO, HIROSHI, OGURO, YANAO, ...
A very rare case of neurogenic sarcoma of the stomach is reported. It is the only case (0.03%) among 3,643 patients with malignant tumors of the stomach operated on at the National Cancer...
Serum Lipids in Patients With Carcinoma and Benign Diseases of the Breast (1980)
ARAKI, EIJI, YAMAGUCHI, MIEKO, YAMAMOTO, HIROSHI, INOUE, GONJI, TOOMA, HIROYUKI, ISHIKAWA, HIROKI, ...
The serum levels of total triacylglycerol, cholesterol and phospholipids in 121 patients with breast carcinoma, 61 patients with benign breast diseases and 145 healthy females were studied especially...
門村, 浩, 高橋, 英紀, 山本, 博, 鈴木, 利吉, Kadomura, Hiroshi, Takahashi, Hidenori, ...
門村, 浩, 高橋, 英紀, 山本, 博, 鈴木, 利吉, Kadomura, Hiroshi, Takahashi, Hidenori, ...
Enzyme Immunoassay of Testosterone Using the Testosterone-Glucoamylase Complex (1976)
TATEISHI, Kayoko, YAMAMOTO, Hiroshi, OGIWARA, Toshio, HAYASHI, Chozo, KITAGAWA, Masayasu
A highly sensitive, reproducible method was established for enzyme-coupled immunoassay of testosterone, involving coupling of testosterone to glucoamylase (EC 3.2.1.3) with a water-soluble coupling...
IDENTIFICATION OF IMMUNOGLOBULINS IN CHICKEN EGGS AND THEIR ANTIBODY ACTIVITY (1975)
YAMAMOTO, Hiroshi, WATANABE, Hiroshi, SATO, Gihei, MIKAMI, Takeshi
The presence of immunoglobulins and a secretory component (SC) in the hen's egg and oviduct washings was investigated. In addition, the existence of transferred antibodies in the yolk and white of...
IDENTIFICATION OF IMMUNOGLOBULINS IN CHICKEN EGGS AND THEIR ANTIBODY ACTIVITY (1975)
YAMAMOTO, Hiroshi, WATANABE, Hiroshi, SATO, Gihei, MIKAMI, Takeshi
IDENTIFICATION OF IMMUNOGLOBULINS IN CHICKEN EGGS AND THEIR ANTIBODY ACTIVITY (1975)
YAMAMOTO, Hiroshi, WATANABE, Hiroshi, SATO, Gihei, MIKAMI, Takeshi
AIKAWA, Tadaomi, MATSUTAKA, Hisako, YAMAMOTO, Hiroshi, OKUDA, Toyoko, ISHIKAWA, Eiji, KAWANO, Tatsu, ...
Studies were made on the relative contributions of amino acids for hepatic gluconeogenesis in vivo and on inter-organal relations in amino acid metabolism in fasted rats. First, the plasma levels of...
MATSUTAKA, Hisako, AIKAWA, Tadaomi, YAMAMOTO, Hiroshi, ISHIKAWA, Eiji
Amino acid metabolism in non-hepatic splanchnic organs of fasted rats was studied both in vitro and in vivo to determine the roles of glutamine, glutamate, alanine, and ammonia in the amino acid...
Somesmall polymers obtained from nitrogen heterocycles (1968)
Processed. Includes bibliography.
Koizumi, Tomonobu, Kubo, Keishi, Kaneki, Toshimichi, Hanaoka, Masayuki, Hayano, Toshihide, Miyahara, Takayuki, ...
We have studied the pharmacokinetics of amphotericin B (AmB) in lung lymph circulation and bronchial-wash fluid after intravenous infusion and inhalation, respectively. For two experiments with awake...
Oxidative stress inhibits the repair of photodamage to the photosynthetic machinery
Nishiyama, Yoshitaka, Yamamoto, Hiroshi, Allakhverdiev, Suleyman I., Inaba, Masami, Yokota, Akiho, Murata, Norio
Absorption of excess light energy by the photosynthetic machinery results in the generation of reactive oxygen species (ROS), such as H2O2. We investigated the effects in vivo of ROS to clarify the...
Yamamoto, Hiroshi, Lee, Charlotte E., Marcus, Jacob N., Williams, Todd D., Overton, J. Michael, Lopez, Marisol E., ...
Glucagon-like peptide-1 (GLP-1) released from the gut functions as an incretin that stimulates insulin secretion. GLP-1 is also a brain neuropeptide that controls feeding and drinking behavior and...
Yamaguchi, Katsushi, Suzuki, Iwane, Yamamoto, Hiroshi, Lyukevich, Alexander, Bodrova, Irina, Los, Dmitry A., ...
Mn is an essential component of the oxygen-evolving machinery of photosynthesis and is an essential cofactor of several important enzymes, such as Mn–superoxide dismutase and Mn-catalase. The...
Nishiyama, Takashi, Yamamoto, Hiroshi, Shibuya, Norihiro, Hatakeyama, Yoshinori, Hachimori, Akira, Uchiumi, Toshio, ...
Plautia stali intestine virus (PSIV) has an internal ribosome entry site (IRES) at the intergenic region of the genome. The PSIV IRES initiates translation with glutamine rather than the universal...
Masuzaki, Hiroaki, Yamamoto, Hiroshi, Kenyon, Christopher J., Elmquist, Joel K., Morton, Nicholas M., Paterson, Janice M., ...
Obesity is closely associated with the metabolic syndrome, a combination of disorders including insulin resistance, diabetes, dyslipidemia, and hypertension. A role for local glucocorticoid...
Marin, Kay, Suzuki, Iwane, Yamaguchi, Katsushi, Ribbeck, Kathrin, Yamamoto, Hiroshi, Kanesaki, Yu, ...
In plants and microorganisms, salt stress regulates the expression of large numbers of genes. However, the machinery that senses salt stress remains to be characterized. In this study we identified...
Allakhverdiev, Suleyman I., Nishiyama, Yoshitaka, Miyairi, Sachio, Yamamoto, Hiroshi, Inagaki, Noritoshi, Kanesaki, Yu, ...
Light stress and salt stress are major environmental factors that limit the efficiency of photosynthesis. However, we have found that the effects of light and salt stress on photosystem II (PSII) in...
Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
Yamamoto, Yasuhiko, Kato, Ichiro, Doi, Toshio, Yonekura, Hideto, Ohashi, Seiji, Takeuchi, Masayoshi, ...
Vascular complications arising from multiple environmental and genetic factors are responsible for many of the disabilities and short life expectancy associated with diabetes mellitus. Here we...
Yamamoto, Hiroshi, Shimojo, Hiroto
Methods to measure T antigen-forming capacities of simian virus 40 (SV40) and adenovirus 12 (Ad12) were investigated, and a method to measure the capacity in terms of T antigen-forming units was...
Yamamoto, Hiroshi, Shimojo, Hiroto
Five out of 120 clones of a cyt mutant of adenovirus 12 were not defective in induction of the cell surface change and in tumorigenicity.
Someya, Kenji, Cecilia, Dayaraj, Ami, Yasushi, Nakasone, Tadashi, Matsuo, Kazuhiro, Burda, Sherri, ...
Although the correlates of vaccine-induced protection against human immunodeficiency virus type 1 (HIV-1) are not fully known, it is presumed that neutralizing antibodies (NAb) play a role in...
Abeyama, Kazuhiro, Stern, David M., Ito, Yuji, Kawahara, Ko-ichi, Yoshimoto, Yasushi, Tanaka, Motoyuki, ...
Thrombomodulin (TM) is an endothelial anticoagulant cofactor that promotes thrombin-mediated formation of activated protein C (APC). We have found that the N-terminal lectin-like domain (D1) of TM...
Yonekura, Hideto, Yamamoto, Yasuhiko, Sakurai, Shigeru, Petrova, Ralica G, Abedin, Md Joynal, Li, Hui, ...
The binding of advanced glycation end-products (AGE) to the receptor for AGE (RAGE) is known to deteriorate various cell functions and is implicated in the pathogenesis of diabetic vascular...
The role of AGE-Rage system in the development of diabetic nephropathy in vivo
Yamamoto, Yasuhiko, Kato, Ichiro, Doi, Toshio, Yonekura, Hideto, Ohashi, Seiji, Takeuchi, Masayoshi, ...
Vascular complications are what eventually threaten the lives of diabetic patients. Here we show direct in vivo evidence that the interaction between advanced glycation end products (AGE), the...
Yamamoto, Yasuhiko, Yonekura, Hideto, Sakurai, Shigeru, Tanaka, Nobushige, Hui, Li, Khin-Mar, Myint, ...
As is diabetes itself, diabetic vasculopathy is a multifactor disease. Studies conducted in this lab revealed advanced glycation endproducts (AGE) as the major environmental account for vascular cell...
Sunahori, Katsue, Yamamura, Masahiro, Yamana, Jiro, Takasugi, Kouji, Kawashima, Masanori, Yamamoto, Hiroshi, ...
S100A8 and S100A9, two Ca2+-binding proteins of the S100 family, are secreted as a heterodimeric complex (S100A8/A9) from neutrophils and monocytes/macrophages. Serum and synovial fluid levels of...
Harashima, Ai, Yamamoto, Yasuhiko, Cheng, Chunmei, Tsuneyama, Koichi, Myint, Khin Mar, Takeuchi, Akihiko, ...
The cell-surface RAGE [receptor for AGE (advanced glycation end-products)] is associated with the development of diabetic vascular complications, neurodegenerative disorders and inflammation....
Koizumi, Tomonobu, Kubo, Keishi, Kaneki, Toshimichi, Hanaoka, Masayuki, Hayano, Toshihide, Miyahara, Takayuki, ...
We have studied the pharmacokinetics of amphotericin B (AmB) in lung lymph circulation and bronchial-wash fluid after intravenous infusion and inhalation, respectively. For two experiments with awake...
Oxidative stress inhibits the repair of photodamage to the photosynthetic machinery
Nishiyama, Yoshitaka, Yamamoto, Hiroshi, Allakhverdiev, Suleyman I., Inaba, Masami, Yokota, Akiho, Murata, Norio
Absorption of excess light energy by the photosynthetic machinery results in the generation of reactive oxygen species (ROS), such as H2O2. We investigated the effects in vivo of ROS to clarify the...
Yamamoto, Hiroshi, Lee, Charlotte E., Marcus, Jacob N., Williams, Todd D., Overton, J. Michael, Lopez, Marisol E., ...
Glucagon-like peptide-1 (GLP-1) released from the gut functions as an incretin that stimulates insulin secretion. GLP-1 is also a brain neuropeptide that controls feeding and drinking behavior and...
Yamaguchi, Katsushi, Suzuki, Iwane, Yamamoto, Hiroshi, Lyukevich, Alexander, Bodrova, Irina, Los, Dmitry A., ...
Mn is an essential component of the oxygen-evolving machinery of photosynthesis and is an essential cofactor of several important enzymes, such as Mn–superoxide dismutase and Mn-catalase. The...
Nishiyama, Takashi, Yamamoto, Hiroshi, Shibuya, Norihiro, Hatakeyama, Yoshinori, Hachimori, Akira, Uchiumi, Toshio, ...
Plautia stali intestine virus (PSIV) has an internal ribosome entry site (IRES) at the intergenic region of the genome. The PSIV IRES initiates translation with glutamine rather than the universal...
Masuzaki, Hiroaki, Yamamoto, Hiroshi, Kenyon, Christopher J., Elmquist, Joel K., Morton, Nicholas M., Paterson, Janice M., ...
Obesity is closely associated with the metabolic syndrome, a combination of disorders including insulin resistance, diabetes, dyslipidemia, and hypertension. A role for local glucocorticoid...
Marin, Kay, Suzuki, Iwane, Yamaguchi, Katsushi, Ribbeck, Kathrin, Yamamoto, Hiroshi, Kanesaki, Yu, ...
In plants and microorganisms, salt stress regulates the expression of large numbers of genes. However, the machinery that senses salt stress remains to be characterized. In this study we identified...
Allakhverdiev, Suleyman I., Nishiyama, Yoshitaka, Miyairi, Sachio, Yamamoto, Hiroshi, Inagaki, Noritoshi, Kanesaki, Yu, ...
Light stress and salt stress are major environmental factors that limit the efficiency of photosynthesis. However, we have found that the effects of light and salt stress on photosystem II (PSII) in...
Development and prevention of advanced diabetic nephropathy in RAGE-overexpressing mice
Yamamoto, Yasuhiko, Kato, Ichiro, Doi, Toshio, Yonekura, Hideto, Ohashi, Seiji, Takeuchi, Masayoshi, ...
Vascular complications arising from multiple environmental and genetic factors are responsible for many of the disabilities and short life expectancy associated with diabetes mellitus. Here we...
Yamamoto, Hiroshi, Shimojo, Hiroto
Methods to measure T antigen-forming capacities of simian virus 40 (SV40) and adenovirus 12 (Ad12) were investigated, and a method to measure the capacity in terms of T antigen-forming units was...
Yamamoto, Hiroshi, Shimojo, Hiroto
Five out of 120 clones of a cyt mutant of adenovirus 12 were not defective in induction of the cell surface change and in tumorigenicity.
Someya, Kenji, Cecilia, Dayaraj, Ami, Yasushi, Nakasone, Tadashi, Matsuo, Kazuhiro, Burda, Sherri, ...
Although the correlates of vaccine-induced protection against human immunodeficiency virus type 1 (HIV-1) are not fully known, it is presumed that neutralizing antibodies (NAb) play a role in...
Abeyama, Kazuhiro, Stern, David M., Ito, Yuji, Kawahara, Ko-ichi, Yoshimoto, Yasushi, Tanaka, Motoyuki, ...
Thrombomodulin (TM) is an endothelial anticoagulant cofactor that promotes thrombin-mediated formation of activated protein C (APC). We have found that the N-terminal lectin-like domain (D1) of TM...
Yonekura, Hideto, Yamamoto, Yasuhiko, Sakurai, Shigeru, Petrova, Ralica G, Abedin, Md Joynal, Li, Hui, ...
The binding of advanced glycation end-products (AGE) to the receptor for AGE (RAGE) is known to deteriorate various cell functions and is implicated in the pathogenesis of diabetic vascular...
Harashima, Ai, Yamamoto, Yasuhiko, Cheng, Chunmei, Tsuneyama, Koichi, Myint, Khin Mar, Takeuchi, Akihiko, ...
The cell-surface RAGE [receptor for AGE (advanced glycation end-products)] is associated with the development of diabetic vascular complications, neurodegenerative disorders and inflammation....
Sunahori, Katsue, Yamamura, Masahiro, Yamana, Jiro, Takasugi, Kouji, Kawashima, Masanori, Yamamoto, Hiroshi, ...
S100A8 and S100A9, two Ca2+-binding proteins of the S100 family, are secreted as a heterodimeric complex (S100A8/A9) from neutrophils and monocytes/macrophages. Serum and synovial fluid levels of...
The role of AGE-Rage system in the development of diabetic nephropathy in vivo
Yamamoto, Yasuhiko, Kato, Ichiro, Doi, Toshio, Yonekura, Hideto, Ohashi, Seiji, Takeuchi, Masayoshi, ...
Vascular complications are what eventually threaten the lives of diabetic patients. Here we show direct in vivo evidence that the interaction between advanced glycation end products (AGE), the...
Yamamoto, Yasuhiko, Yonekura, Hideto, Sakurai, Shigeru, Tanaka, Nobushige, Hui, Li, Khin-Mar, Myint, ...
As is diabetes itself, diabetic vasculopathy is a multifactor disease. Studies conducted in this lab revealed advanced glycation endproducts (AGE) as the major environmental account for vascular cell...
Shimozato, Osamu, Ugai, Shin-ichi, Chiyo, Masako, Takenobu, Hisanori, Nagakawa, Hiroyasu, Wada, Akihiko, ...
Interleukin (IL)-23 is a heterodimeric cytokine consisting of a novel p19 molecule and the p40 subunit of IL-12. Since secreted p40 can act as an antagonist for IL-12, we investigated whether p40...
Kohama, Yasuhiro, Shinoda, Shinji, Hagihara, Katsunobu, Hashimoto, Takeshi, Yamaguchi, Asuka, Nakamura, Akihiro, ...
An athymic mouse-derived immature T-cell clone, N-9F, was not maintained by interleukin-2 alone but required another soluble factor, contained in concanavalin A-stimulated rat splenocyte culture...
Nishiyama, Takashi, Yamamoto, Hiroshi, Uchiumi, Toshio, Nakashima, Nobuhiko
The intergenic region-internal ribosome entry site (IGR-IRES) of dicistroviruses binds to 40S ribosomal subunits in the absence of eukaryotic initiation factors (eIFs). Although the conserved loop...
矢野, 嘉政, 永田, 松夫(1951-), ナガタ,マツオ, Nagata,Matsuo, 山本, 宏(1953-), ヤマモト,ヒロシ, ...
RAGE and Soluble RAGE: Potential Therapeutic Targets for Cardiovascular Diseases
Koyama, Hidenori, Yamamoto, Hiroshi, Nishizawa, Yoshiki
Receptor for advanced glycation end-products (RAGE) is known to be involved in microvascular complications in diabetes. RAGE is also profoundly associated with macrovascular complications in diabetes...
Akabori, Hiroya, Yamamoto, Hiroshi, Tsuchihashi, Hiroshi, Mori, Tsuyoshi, Fujino, Kazunori, Shimizu, Tomoharu, ...
TRPV1 may be involved in the regulation of the cardiovascular responses to hemorrhagic shock. Capsazepine appears to be potentially therapeutically useful for hemorrhage shock.
Kageyama, Shunsuke, Yamamoto, Hiroshi, Nagano, Mitsuyo, Arisaka, Harumi, Kayahara, Takashi, Yoshimoto, Ryota
A murine anti-human vWF monoclonal antibody, AJvW-2, was developed that inhibited the interaction between platelet glycoprotein Ib (GPIb) and von Willebrand factor (vWF) during the ristocetin-...
Tsujikawa, Kazutake, Yayama, Katsutoshi, Hayashi, Tamon, Matsushita, Hiroaki, Yamaguchi, Taijiro, Shigeno, Tomomi, ...
Calcitonin gene-related peptide (CGRP) is thought to be a prominent neuropeptide in cardiovascular regulation and neuroimmune modulation. There are two isoforms of CGRP (αCGRP and βCGRP), and the...
Endogenous Secretory RAGE as a Novel Biomarker for Metabolic Syndrome and Cardiovascular Diseases
Koyama, Hidenori, Yamamoto, Hiroshi, Nishizawa, Yoshiki
Receptor for advanced glycation end-products (RAGE) is known to be involved in both micro- and macro-vascular complications in diabetes. Among numerous truncated forms of RAGE recently described, the...
Effects of Randomness on Power Law Tails in Multiplicatively Interacting Stochastic Processes
Toshiya Ohtsuki, Akihiro Fujihara, Hiroshi Yamamoto
Effects of randomness on non-integer power law tails in multiplicatively interacting stochastic processes are investigated theoretically. Generally, randomness causes decrease of the exponent of...
Asymptotic analysis of the model for distribution of high-tax payers
Hiroshi Yamamoto, Toshiya Ohtsuki, Akihiro Fujihara, Satoshi Tanimoto, Keizo Yamamoto, Sasuke Miyazima
The z-transform technique is used to investigate the model for distribution of high-tax payers, which is proposed by two of the authors (K. Y and S. M) and others. Our analysis shows an asymptotic...