Yamada, Hidetaka, Shinmura, Kazuya, Goto, Masanori, Iwaizumi, Moriya, Konno, Hiroyuki, Kataoka, Hideki, ...
Abstract Background Germline mono-allelic promoter hypermethylation of the MLH1 or MSH2 gene in families with hereditary nonpolyposis colorectal cancer has recently been reported. The purpose of this...
Altered expression of the human base excision repair gene NTH1 in gastric cancer (2009)
Goto, Masanori, Shinmura, Kazuya, Igarashi, Hisaki, Kobayashi, Minatsu, Konno, Hiroyuki, Yamada, Hidetaka, ...
A base excision repair enzyme, NTH1, has activity that is capable of removing oxidized pyrimidines, such as thymine glycol (Tg), from DNA. To clarify whether the NTH1 gene is involved in gastric...
ARA54 is involved in transcriptional regulation of the cyclin D1 gene in human cancer cells (2007)
Kikuchi, Hirotoshi, Uchida, Chiharu, Hattori, Takayuki, Isobe, Tomoyasu, Hiramatsu, Yoshihiro, Kitagawa, Kyoko, ...
Cyclin D1 is one of the major enhancers of cell cycle progression and its expression is regulated in several growth stimulatory signaling pathways. ARA54 is an androgen receptor (AR) co-activator...
Chromosomal Numerical Abnormality Profiles of Gastrointestinal Stromal Tumors (2006)
Yamashita, Kimihiro, Igarashi, Hisaki, Kitayama, Yasuhiko, Ozawa, Takachika, Kiyose, Shinichiro, Konno, Hiroyuki, ...
Background: Biological variations in and the heterogeneity of gastrointestinal stromal tumors (GISTs) are well known, but chromosomal numerical abnormality (CNA) has not been fully examined...
Chromosomal Numerical Abnormality Profiles of Gastrointestinal Stromal Tumors (2006)
Yamashita, Kimihiro, Igarashi, Hisaki, Kitayama, Yasuhiko, Ozawa, Takachika, Kiyose, Shinichiro, Konno, Hiroyuki, ...
Background: Biological variations in and the heterogeneity of gastrointestinal stromal tumors (GISTs) are well known, but chromosomal numerical abnormality (CNA) has not been fully examined...
Sunayama, Ken-ichi, Konno, Hiroyuki, Nakamura, Toshio, Kashiwabara, Hidehumi, Shoji, Tsuyoshi, Tsuneyoshi, Toshihiro, ...
The expression of COX-2 participates strongly in polyp formation of adenomatous polyposis coli (APC)-mutated mice. However, the mechanism of growth inhibition by COX-2 inhibition remains unclear. The...