Hitomi Takahira

Selective loss of GABAB receptors in orexin/hypocretin-producing neurons results in disrupted sleep/wakefulness architecture (2007)

Takeshi Sakurai, Taizo Matsuki, Hitomi Takahira, Noriko Hirashima, Thomas Kilduff, Satoshi Kunita, ...

We generated mice with a selective loss of GABAB receptors in orexin neurons. Orexin neurons in these GABAB1^-/-(orexin) mice showed reduced responsiveness to...

Selective loss of GABAB receptors in orexin-producing neurons results in disrupted sleep/wakefulness architecture

Matsuki, Taizo, Nomiyama, Mika, Takahira, Hitomi, Hirashima, Noriko, Kunita, Satoshi, Takahashi, Satoru, ...

Hypothalamic neurons that contain the neuropeptide orexin (hypocretin) play important roles in the regulation of sleep/wake. Here we analyze the in vivo and in vitro phenotype of mice lacking the...