Karlsson, Jenny, Pütsep, Katrin, Chu, Hiutung, Kays, Robert J, Bevins, Charles L, Andersson, Mats
Abstract Background Enteric antimicrobial peptides secreted from Paneth cells, including α-defensins (in mice named cryptdins), are key effector molecules of innate immunity in the small intestine....
Reduced Paneth cell α-defensins in ileal Crohn's disease
Wehkamp, Jan, Salzman, Nita H., Porter, Edith, Nuding, Sabine, Weichenthal, Michael, Petras, Robert E., ...
The pathogenesis of Crohn′s disease (CD), an idiopathic inflammatory bowel disease, is attributed, in part, to intestinal bacteria that may initiate and perpetuate mucosal inflammation in...
Reduced Paneth cell α-defensins in ileal Crohn's disease
Wehkamp, Jan, Salzman, Nita H., Porter, Edith, Nuding, Sabine, Weichenthal, Michael, Petras, Robert E., ...
The pathogenesis of Crohn′s disease (CD), an idiopathic inflammatory bowel disease, is attributed, in part, to intestinal bacteria that may initiate and perpetuate mucosal inflammation in...
Raffatellu, Manuela, Santos, Renato L., Chessa, Daniela, Wilson, R. Paul, Winter, Sebastian E., Rossetti, Carlos A., ...
The viaB locus contains genes for the biosynthesis and export of the Vi capsular antigen of Salmonella enterica serotype Typhi. Wild-type serotype Typhi induces less CXC chemokine production in...
Regional variations in Paneth cell antimicrobial peptide expression along the mouse intestinal tract
Karlsson, Jenny, Pütsep, Katrin, Chu, Hiutung, Kays, Robert J, Bevins, Charles L, Andersson, Mats
Regulation of C-type Lectin Antimicrobial Activity by a Flexible N-terminal Prosegment*S⃞
Mukherjee, Sohini, Partch, Carrie L., Lehotzky, Rebecca E., Whitham, Cecilia V., Chu, Hiutung, Bevins, Charles L., ...
Members of the RegIII family of intestinal C-type lectins are directly antibacterial proteins that play a vital role in maintaining host-bacterial homeostasis in the mammalian gut, yet little is...
Godinez, Ivan, Raffatellu, Manuela, Chu, Hiutung, Paixão, Tatiane A., Haneda, Takeshi, Santos, Renato L., ...
Salmonella enterica serotype Typhimurium causes an acute inflammatory reaction in the ceca of streptomycin-pretreated mice that involves T-cell-dependent induction of gamma interferon (IFN-γ),...