Skulina, Christian, Schmidt, Stephan, Dornmair, Klaus, Babbe, Holger, Roers, Axel, Rajewsky, Klaus, ...
Trotz erheblicher Forschungsanstrengungen ist die Pathogenese der Multiplen Sklerose (MS) nach wie vor weitgehend ungeklärt. Die MS-Läsion - das charakteristische pathologische Kennzeichen der...
Erscheinungsjahr auf Haupttitels.: 2001
Köln, Univ., Diss., 2002.
Hofbauer, Monika, Wiesener, Solveigh, Babbe, Holger, Roers, Axel, Wekerle, Hartmut, Dornmair, Klaus, ...
Clonal expansions of CD8+ T cells have been identified in muscle and blood of polymyositis patients by PCR techniques, including T cell receptor (TCR) complementarity-determining region (CDR)3 length...
Skulina, Christian, Schmidt, Stephan, Dornmair, Klaus, Babbe, Holger, Roers, Axel, Rajewsky, Klaus, ...
We surveyed the T cell receptor repertoire in three separate compartments (brain, cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic brain biopsies to...
Hofbauer, Monika, Wiesener, Solveigh, Babbe, Holger, Roers, Axel, Wekerle, Hartmut, Dornmair, Klaus, ...
Clonal expansions of CD8+ T cells have been identified in muscle and blood of polymyositis patients by PCR techniques, including T cell receptor (TCR) complementarity-determining region (CDR)3 length...
Skulina, Christian, Schmidt, Stephan, Dornmair, Klaus, Babbe, Holger, Roers, Axel, Rajewsky, Klaus, ...
We surveyed the T cell receptor repertoire in three separate compartments (brain, cerebrospinal fluid, and blood) of two multiple sclerosis patients who initially had diagnostic brain biopsies to...
Mutation of the Murine Bloom's Syndrome Gene Produces Global Genome Destabilization
Chester, Nicholas, Babbe, Holger, Pinkas, Jan, Manning, Charlene, Leder, Philip
Bloom's syndrome (BS) is a genetic disorder characterized cellularly by increases in sister chromatid exchanges (SCEs) and numbers of micronuclei. BS is caused by mutation in the BLM DNA helicase...
The Bloom's Syndrome Helicase Is Critical for Development and Function of the αβ T-Cell Lineage▿ †
Babbe, Holger, Chester, Nicholas, Leder, Philip, Reizis, Boris
Bloom's syndrome is a genetic disorder characterized by increased incidence of cancer and an immunodeficiency of unknown origin. The BLM gene mutated in Bloom's syndrome encodes a DNA helicase...
Babbe, Holger, Roers, Axel, Waisman, Ari, Lassmann, Hans, Goebels, Norbert, Hohlfeld, Reinhard, ...
Clonal composition and T cell receptor (TCR) repertoire of CD4+ and CD8+ T cells infiltrating actively demyelinating multiple sclerosis (MS) lesions were determined with unprecedented resolution at...