Holger Römpler

The Genetic Basis of Phenotypic Convergence in Beach Mice: Similar Pigment Patterns but Different Genes (2009)

Steiner, Cynthia C., Römpler, Holger, Boettger, Linda M., Schöneberg, Torsten, Hoekstra, Hopi E.

Convergent evolution is a widespread phenomenon seen in diverse organisms inhabiting similar selective environments. However, it is unclear if similar phenotypes are produced by the same or different...

Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo (2004)

Sangkuhl, Katrin, Schulz, Angela, Römpler, Holger, Yun, June, Wess, Jürgen, Schöneberg, Torsten

Many human diseases are caused by inactivating mutations in specific G-protein-coupled receptors (GPCRs). In about 10% of these cases, a premature stop codon leads to the generation of a truncated,...

Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo (2004)

Sangkuhl, Katrin, Schulz, Angela, Römpler, Holger, Yun, June, Wess, Jürgen, Schöneberg, Torsten

Many human diseases are caused by inactivating mutations in specific G-protein-coupled receptors (GPCRs). In about 10% of these cases, a premature stop codon leads to the generation of a...

Aminoglycoside-mediated rescue of a disease-causing nonsense mutation in the V2 vasopressin receptor gene in vitro and in vivo (2004)

Sangkuhl, Katrin, Schulz, Angela, Römpler, Holger, Yun, June, Wess, Jürgen, Schöneberg, Torsten

Many human diseases are caused by inactivating mutations in specific G-protein-coupled receptors (GPCRs). In about 10% of these cases, a premature stop codon leads to the generation of a truncated,...

Involvement of the V2 Vasopressin Receptor in Adaptation to Limited Water Supply

Böselt, Iris, Römpler, Holger, Hermsdorf, Thomas, Thor, Doreen, Busch, Wibke, Schulz, Angela, ...

Mammals adapted to a great variety of habitats with different accessibility to water. In addition to changes in kidney morphology, e.g. the length of the loops of Henle, several hormone systems are...